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1. 发明专利

JPH04632B2 失效
公开(公告)号：JPH04632B2
公开(公告)日：1992-01-08
申请号：JP11989082
申请日：1982-07-12
申请人： SEIKENKAI
发明人： HATA KOSEI , MARUOKA TOSHUKI
IPC分类号： A23C13/16 , A23C9/123 , A23L9/20 , A23L29/00 , A61K35/74 , A61K35/747 , A61P1/12 , C12N1/20 , C12R1/225
摘要： A novel Lactobacillus clearans, Lactobacillus sulfurica and Lactobacillus nitrosus:Which can decrease both Na 2 S.9H 2 0 and/or NH 3 when inoculated and cultured on:a medium comprising 5 g of meat extract, 5 g of peptone, 0.5 g of Na 2 S.9H 2 O, 5 g of glucose, 1 g of CaCO 3 , 0.5 ml of NH 3 (as 100% ammonia) and 1 liter of water (pH, neutral);which shows no growth acceleration action even when said bacteria is cultured on a medium comprising a Stephenson-Wetham medium (hereafter merely referred to as (S-W); KH 2 PO 4 1 g, MgSO 4 .7H 2 O 0.7 g, NaCl 1g, (NH 4 ) 2 HPO 4 4 g; FeSO 4 .7H 2 O 0.03 g, glucose 5 g) + vitamins (A: 900 IU, B 1 : 1 mg, B 2 : 1 mg, B 6 : 1 mg, B 12 : 5 gamma, nicotinamide: 1.6 mg, calcium pantothenate: 8 mg, C: 64 mg, D 2 : 120 IU) + casamino acid 1 g and 0.5 g of Na 2 S.9H 2 0 and/or 0.5 ml (100% conversion) of NH 3 are incorporated at the logarithmic growth phase; and;which has the following characteristics:gram-positive, rod, non-motile, catalase-negative, no reduction of nitrates, no decomposition of gelatin, no formation of indole or hydrogen sulfide, high ability of forming lactic acid from glucose and lactose, and growth being accelerated by the addition of acetic acid.

2. 发明专利

JPS5478859A PURIFIER* METHODS OF FABRICATING AND RESERVING SAME 失效
公开(公告)号：JPS5478859A
公开(公告)日：1979-06-23
申请号：JP14554677
申请日：1977-12-04
申请人： SEIKENKAI
发明人： HATA OKIMASA , MARUOKA TOSHIYUKI , HATA TADATSUGU
IPC分类号： C02F3/34 , C12N1/00

3. 发明专利

JPS5218879A METHOD FOR CULTURING A STOOL DEODORANT GERM BELONGING TO LACTOBACILLUS GENUS 失效
公开(公告)号：JPS5218879A
公开(公告)日：1977-02-12
申请号：JP7949475
申请日：1975-06-24
申请人： SEIKENKAI
发明人： HATA NORIYO , MARUOKA TOSHIYUKI , HATA TADATSUGU
IPC分类号： C02F3/34 , A61L9/01 , C12N1/00 , C12R1/225
摘要： PURPOSE:An efficient method for culturing stool deodorant germ which belongs to Lactobacillus and deodorizes in the intestine, by adding stool odorous components to its medium.

4. 发明专利

JPS51102356A 失效
公开(公告)号：JPS51102356A
公开(公告)日：1976-09-09
申请号：JP2776275
申请日：1975-03-05
申请人： SEIKENKAI
发明人： HATA KOSEI , HATA TADATSUGU , MARUOKA TOSHUKI
IPC分类号： C02F3/00 , A61L9/00 , A61L9/01 , A62D3/00 , A62D3/02 , C02F3/34 , C11D1/00

5. 发明专利

AU556996B2 LACTOBACILLUS 未知
公开(公告)号：AU556996B2
公开(公告)日：1986-11-27
申请号：AU1676583
申请日：1983-07-12
申请人： SEIKENKAI
发明人： HATA KOSEI , MARUOKA TOSHIYUKI
IPC分类号： A23C13/16 , A23C9/123 , A23L9/20 , A23L29/00 , A61K35/74 , A61K35/747 , A61P1/12 , C12N1/20 , C12R1/225 , A23L1/30 , A23L3/00
摘要： A novel Lactobacillus clearans, Lactobacillus sulfurica and Lactobacillus nitrosus:Which can decrease both Na 2 S.9H 2 0 and/or NH 3 when inoculated and cultured on:a medium comprising 5 g of meat extract, 5 g of peptone, 0.5 g of Na 2 S.9H 2 O, 5 g of glucose, 1 g of CaCO 3 , 0.5 ml of NH 3 (as 100% ammonia) and 1 liter of water (pH, neutral);which shows no growth acceleration action even when said bacteria is cultured on a medium comprising a Stephenson-Wetham medium (hereafter merely referred to as (S-W); KH 2 PO 4 1 g, MgSO 4 .7H 2 O 0.7 g, NaCl 1g, (NH 4 ) 2 HPO 4 4 g; FeSO 4 .7H 2 O 0.03 g, glucose 5 g) + vitamins (A: 900 IU, B 1 : 1 mg, B 2 : 1 mg, B 6 : 1 mg, B 12 : 5 gamma, nicotinamide: 1.6 mg, calcium pantothenate: 8 mg, C: 64 mg, D 2 : 120 IU) + casamino acid 1 g and 0.5 g of Na 2 S.9H 2 0 and/or 0.5 ml (100% conversion) of NH 3 are incorporated at the logarithmic growth phase; and;which has the following characteristics:gram-positive, rod, non-motile, catalase-negative, no reduction of nitrates, no decomposition of gelatin, no formation of indole or hydrogen sulfide, high ability of forming lactic acid from glucose and lactose, and growth being accelerated by the addition of acetic acid.

6. 发明专利

BR8303725A 未知
公开(公告)号：BR8303725A
公开(公告)日：1984-02-14
申请号：BR8303725
申请日：1983-07-12
申请人： SEIKENKAI
发明人： HATA KOSEI , MARUOKA TOSHIYKI
IPC分类号： A23C13/16 , A23C9/123 , A23L9/20 , A23L29/00 , A61K35/74 , A61K35/747 , A61P1/12 , C12N1/20 , C12R1/225
摘要： A novel Lactobacillus clearans, Lactobacillus sulfurica and Lactobacillus nitrosus:Which can decrease both Na 2 S.9H 2 0 and/or NH 3 when inoculated and cultured on:a medium comprising 5 g of meat extract, 5 g of peptone, 0.5 g of Na 2 S.9H 2 O, 5 g of glucose, 1 g of CaCO 3 , 0.5 ml of NH 3 (as 100% ammonia) and 1 liter of water (pH, neutral);which shows no growth acceleration action even when said bacteria is cultured on a medium comprising a Stephenson-Wetham medium (hereafter merely referred to as (S-W); KH 2 PO 4 1 g, MgSO 4 .7H 2 O 0.7 g, NaCl 1g, (NH 4 ) 2 HPO 4 4 g; FeSO 4 .7H 2 O 0.03 g, glucose 5 g) + vitamins (A: 900 IU, B 1 : 1 mg, B 2 : 1 mg, B 6 : 1 mg, B 12 : 5 gamma, nicotinamide: 1.6 mg, calcium pantothenate: 8 mg, C: 64 mg, D 2 : 120 IU) + casamino acid 1 g and 0.5 g of Na 2 S.9H 2 0 and/or 0.5 ml (100% conversion) of NH 3 are incorporated at the logarithmic growth phase; and;which has the following characteristics:gram-positive, rod, non-motile, catalase-negative, no reduction of nitrates, no decomposition of gelatin, no formation of indole or hydrogen sulfide, high ability of forming lactic acid from glucose and lactose, and growth being accelerated by the addition of acetic acid.

7. 发明专利

BR7703307A 未知
公开(公告)号：BR7703307A
公开(公告)日：1978-01-31
申请号：BR7703307
申请日：1977-05-23
申请人： SEIKENKAI
发明人： HATA K
IPC分类号： A23K10/12 , A23K10/18 , A23K10/26 , A23K20/00 , A23K20/142 , A23L31/00 , A61K8/99 , A61K35/74 , A61L9/01 , A61L11/00 , A61Q15/00 , C12N1/00 , C12N1/04 , C12N1/20 , C12N1/38 , C12K1/06 , A61K7/32 , C12K1/08

8. 发明专利

CA1274482A BIODEODORIZER AND THE PROCESS THEREOF 未知
公开(公告)号：CA1274482A
公开(公告)日：1990-09-25
申请号：CA486901
申请日：1985-07-16
申请人： SEIKENKAI
发明人： HATA KOSEI , MARUOKA TOSHIYUKI
IPC分类号： A61K35/74 , C12N1/20
摘要： A biodeodorizer and a process to prepare the biodeodorizer are described, the biodeodorizer comprising (a) at least one strain selected from the group consisting of Lactobacillus deodorans, Lactobacillus clearans and a mixed strain of Lactobacillus sulfurica and Lactobacillus nitrosus, and (b) Streptococcus faecalis having the ability to produce antibiotics.

9. 发明专利

IN162045B A PROCESS FOR PREPARING A BIODEODORIZER 未知
公开(公告)号：IN162045B
公开(公告)日：1988-03-19
申请号：IN548MA1985
申请日：1985-07-16
申请人： SEIKENKAI
发明人： KOSEI HATA , TOSHIYUKI MARUOKA
IPC分类号： A61K7/00

10. 发明专利

JPS6234731B2 失效
公开(公告)号：JPS6234731B2
公开(公告)日：1987-07-28
申请号：JP1922676
申请日：1976-02-23
申请人： SEIKENKAI
发明人： HATA KOSEI , HATA TADATSUGU , MARUOKA TOSHUKI
IPC分类号： C12N1/00 , A61K35/74 , A61K35/747 , A61P1/00 , A61P27/16 , A61P31/04
摘要： This invention comprising a single or plural strains of Lactobacillus having special characteristics that have been never known is a new type of pharmaceutical Lactobacillus preparation for the treatment of infectious diseases. Some of the characteristics of Lactobacillus used for the present invention as as follows. (a) They are able to grow in low nutrition. (b) The speed of multiplication is quick. (c) By odoriferous S-, N- & C-compound, is promoted the growth. The effects of the present invention are as follows. Unlike the antibiotics which serves only to kill the bacteria, the present preparation is characteristic in that (a) it is non-pathogenic; (b) it can produce antibiotics thereby killing bacteria; (c) it can survive in the growth competition with pathogenic or other bacteria; (d) it denatures the metabolites (including poisonous ones) of living bodies or convert them into constituents of its own cells; (e) it purifies an affected part; (f) it shows anti-inflammatory or anti-swelling activities; and finally (g), as said preparation is foreign to the living bodies and is non-pathogenic, it is at least digested after the inflammatory diseases disappear. Accordingly, the present invention can be used extensively to give better therapeutic effects, except where the physical structure does not permit to use it.

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