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1. 发明申请

WO2012010215A1 NON-PLANAR TREATMENT BEAM CONTROL 审中-公开
标题翻译：非平面处理梁控制
公开(公告)号：WO2012010215A1
公开(公告)日：2012-01-26
申请号：PCT/EP2010/060710
申请日：2010-07-23
申请人： BrainLAB AG , FROEHLICH, Stephan , GUM, Franz , BERLINGER, Kajetan
发明人： FROEHLICH, Stephan , GUM, Franz , BERLINGER, Kajetan
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61N5/10 , A61N5/103 , A61N5/1042 , A61N5/1082
摘要： The present invention relates to a data processing method for determining control data for controlling beam positions which beam positions describe positions which a treatment beam has or would have if emitted by a beam source, the treatment beam being for treating a treatment body part of a patient, said method constituted to be performed by a computer and comprising the steps of: • providing treatment data which comprise data on a position of the treatment body part; • providing condition data which describe: constraints on the beam positions and/or constraints on positional changes of the beam positions, wherein said constraints allow for at least a part of the beam positions to lie not in a common plane; • providing an arrangement of the beam positions on the basis of the treatment data which arrangement fulfils the condition data; • determining control data for controlling a change of a relative position of the beam source relative to the treatment body part for changing the beam positions and for controlling an emission of the treatment beam from the beam source, the determined control data being constituted to change the beam positions to follow the provided arrangement of the beam positions and to cause continuous emission of the treatment beam during a continuous change of the beam positions while the beam positions follow at least a part of the arrangement.
摘要翻译：本发明涉及一种用于确定用于控制光束位置的控制数据的数据处理方法，所述光束位置描述了由光束源发射时处理光束具有或将具有的位置，所述处理光束用于治疗患者的治疗主体部分所述方法构成为由计算机执行，并且包括以下步骤：提供处理数据，其包括关于处理主体部分的位置的数据; °提供条件数据，其描述：对波束位置的约束和/或波束位置的位置变化的约束，其中所述约束允许波束位置的至少一部分不在公共平面内; °基于处理数据提供波束位置的布置，该布置满足条件数据; °确定控制数据，用于控制用于改变光束位置的光束源相对于处理体部分的相对位置的改变，并且用于控制来自光束源的处理光束的发射，所确定的控制数据被构造成改变光束位置跟随所提供的光束位置的布置，并且在光束位置的连续变化期间引起处理光束的连续发射，而光束位置遵循该布置的至少一部分。

2. 发明申请

WO2013017164A2 DOSE-OPTIMISED PATIENT POSITIONING FOR RADIOTHERAPY 审中-公开
标题翻译：用于放射治疗的剂量优化患者定位
公开(公告)号：WO2013017164A2
公开(公告)日：2013-02-07
申请号：PCT/EP2011/063285
申请日：2011-08-02
申请人： BRAINLAB AG , GUM, Franz , FROEHLICH, Stephan
发明人： GUM, Franz , FROEHLICH, Stephan
IPC分类号： A61N5/10
CPC分类号： A61N5/1039 , A61B6/032 , A61B6/4085 , A61N5/1031 , A61N5/1048 , A61N5/1049 , A61N5/1077 , A61N2005/1061

3. 发明申请

WO2018019388A1 SYSTEM FOR MONITORING THE POSITION OF A PATIENT RECEIVING 4π RADIATION THERAPY 审中-公开
标题翻译：监测患者接受4π辐射治疗的位置的系统
公开(公告)号：WO2018019388A1
公开(公告)日：2018-02-01
申请号：PCT/EP2016/068196
申请日：2016-07-29
申请人： BRAINLAB AG
发明人： BERLINGER, Kajetan , FROEHLICH, Stephan
IPC分类号： A61N5/10
摘要： Disclosed is a computer-implemented medical data processing method for determining a deviation between a pianned and an actual relative position between an anatomical body of a patient's body, the method comprising executing, on at least one processor of at least one computer, steps of: a) acquiring (S11), at the at least one processor, planned control point data describing predetermined control points each describing a predetermined operational state of the radiation treatment apparatus, the control points having a predetermined temporal order in which they are planned to be assumed by the radiation treatment apparatus and each control point being associated with a predetermined planned relative position between the anatomical body part and a monitoring imaging apparatus; b) determining (S12), at the at least one processor, current control point data describing whether the radiation treatment apparatus has assumed a predetermined control point; c) acquiring (S13), at the at least one processor, monitoring image data describing at least one digital medical monitoring image of the anatomical body part in at least one monitoring relative position between the anatomical body part and the monitoring imaging apparatus, wherein the monitoring imaging apparatus is used to generate the monitoring image; d) acquiring (S14), at the at least one processor, patient image data describing a predetermined medical image of the anatomical body part; e) determining (S15), by the at least one processor and based on the patient image data and the current control point data and the planned control point data, comparison image data describing at least one digital medical comparison image of the anatomical body part in the monitoring relative position; f) determining (S16), by the at least one processor and based on the comparison image data and the monitoring image data, position deviation data describing a positional deviation between the pianned relative position associated with the planned control point assumed by the radiation treatment apparatus on the one hand and the monitoring relative position on the other hand.
摘要翻译：公开了一种用于确定患者身体的解剖身体之间的扁平和实际相对位置之间的偏差的计算机实现的医疗数据处理方法，所述方法包括：在至少一个处理器至少一个计算机执行以下步骤：a）在所述至少一个处理器处获取（S11）计划控制点数据，所述计划控制点数据描述预定控制点，每个预定控制点描述所述放射治疗装置的预定操作状态，所述控制点具有预定时间顺序其中它们被规划为由放射治疗设备采用并且每个控制点与解剖身体部位和监测成像设备之间的预定计划相对位置相关联; b）在所述至少一个处理器处确定（S12）当前控制点数据，所述当前控制点数据描述所述放射治疗装置是否已经呈现预定控制点; c）在所述至少一个处理器处获取（S13）在所述解剖身体部位与所述监测成像装置之间的至少一个监测相对位置处监测描述所述解剖身体部位的至少一个数字医学监测图像的图像数据，其中所述监视成像装置用于生成监视图像; d）在所述至少一个处理器处获取（S14）描述所述解剖身体部位的预定医学图像的患者图像数据; e）由所述至少一个处理器并且基于患者图像数据和当前控制点数据以及计划控制点数据来确定（S15）比较图像数据，所述比较图像数据描述所述解剖身体部位的至少一个数字医学比较图像监测相对位置; f）由所述至少一个处理器并且基于所述比较图像数据和所述监测图像数据来确定（S16）位置偏差数据，所述位置偏差数据描述与由所述放射治疗设备假定的所述计划控制点相关联的所述弹性相对位置另一方面监控相对位置。

4. 发明申请

WO2016086976A1 HUMAN BODY MEASUREMENT USING THERMOGRAPHIC IMAGES 审中-公开
标题翻译：人体测量使用热像图像
公开(公告)号：WO2016086976A1
公开(公告)日：2016-06-09
申请号：PCT/EP2014/076287
申请日：2014-12-02
申请人： BRAINLAB AG
发明人： KAISER, Hagen , FROEHLICH, Stephan , VILSMEIER, Stephan
IPC分类号： A61B5/01 , G03B35/00 , H04N13/02
CPC分类号： A61B5/1128 , A61B5/0035 , A61B5/0064 , A61B5/0077 , A61B5/015 , A61B5/055 , A61B5/11 , A61B5/113 , A61B5/7292 , A61B6/032 , A61B6/5247 , A61B2560/0223 , A61B2576/00 , A61B2576/02 , A61N5/1049 , A61N5/1068 , A61N5/1069 , G01J5/00 , G01J5/10 , G01J2005/0077 , G01J2005/0081 , G01R33/4808 , G03B35/02 , G06F19/00 , G06T7/0012 , G06T7/33 , G06T7/70 , G06T2207/10004 , G06T2207/10028 , G06T2207/10048 , G06T2207/10081 , G06T2207/10088 , G06T2207/30196 , H04N13/204 , H04N13/239 , H04N2013/0081
摘要： A medical data processing method, performed by a computer, for measuring the spatial location of a point on the surface of the body of a patient, comprising the steps of: - acquiring at least two two-dimensional image datasets, wherein each two-dimensional image dataset represents a two-dimensional image of at least a part of the surface which comprises the point, and wherein the two-dimensional images are taken from different and known viewing directions; - determining the pixels in the two-dimensional image datasets which show said point on the surface of the body; and - calculating the spatial location of the point from the locations of the determined pixels in the two-dimensional image datasets and the viewing directions of the two- dimensional images; wherein the two-dimensional images are thermographic images.
摘要翻译：一种由计算机执行的用于测量患者身体表面上的点的空间位置的医疗数据处理方法，包括以下步骤： - 获取至少两个二维图像数据集，其中每个二维图像数据集表示包括该点的表面的至少一部分的二维图像，并且其中二维图像取自不同的和已知的观看方向; - 确定显示身体表面上的所述点的二维图像数据集中的像素; 以及 - 从二维图像数据集中的确定的像素的位置和二维图像的观看方向计算点的空间位置; 其中所述二维图像是热成像图像。

5. 发明申请

WO2015120906A1 FRAMELESS PRE-POSITIONING FOR RADIOSURGERY 审中-公开
标题翻译：无缝预处理放射治疗
公开(公告)号：WO2015120906A1
公开(公告)日：2015-08-20
申请号：PCT/EP2014/052932
申请日：2014-02-14
申请人： BRAINLAB AG
发明人： GRUBER, Eva Maria , BERLINGER, Kajetan , FROEHLICH, Stephan
IPC分类号： A61B6/00 , A61N5/10
CPC分类号： A61B6/0492 , A61B6/032 , A61B6/0421 , A61B6/501 , A61B6/5211 , A61B6/547 , A61B90/14 , A61B90/39 , A61B2034/2055 , A61B2090/101 , A61B2090/364 , A61B2090/3937 , A61B2090/3983 , A61N5/1049 , A61N5/1069 , A61N2005/1061 , G01T7/005 , G06F19/00 , G06K9/00208 , G06K9/2054 , G06K9/2063 , G06K9/32 , G06K9/3216 , G06K9/6212 , G06K2009/2045 , G06K2009/3225 , G06K2009/3291 , G06T7/0014 , G06T7/74 , G06T2207/10081 , G06T2207/20221 , G06T2207/30004 , G06T2207/30204 , G06T2207/30208 , G06T2219/2004
摘要： A medical data processing method of determining positioning control data describing a positioning procedure for positioning an anatomical body part (2) of a patient (1), the method being constituted to be executed by a computer (11) and comprising the following steps: a) acquiring (SI) reference medical image data describing a reference image representation of a reference structure (3); b) acquiring (S2) patient medical image data describing a patient image representation of the anatomical body part (2) and the reference structure (3); c) acquiring treatment position data describing a predetermined treatment position of the anatomical body part (2) which it shall attain for conducting an envisaged medical procedure; d) acquiring marker reference position data describing a predetermined spatial relationship between a marker device (4) and the reference structure (3); e) acquiring actual marker position data describing the actual position of the marker device (4); f) determining, based on the reference medical image data and the patient medical image data, body part reference position data describing the spatial relationship between the anatomical body part (2) and the reference structure (3); g) determining, based on the body part reference position data and the marker reference position data, body part marker position data describing the spatial relationship between the anatomical body part (2) and the marker device (4); h) determining (S4), based on the treatment position data and the marker reference position data and the body part marker position data, positioning control data describing a positioning procedure for positioning the anatomical body part (2).
摘要翻译：一种医疗数据处理方法，用于确定描述用于定位患者（1）的解剖体部分（2）的定位过程的定位控制数据，所述方法被构造为由计算机（11）执行，并且包括以下步骤：获取描述参考结构（3）的参考图像表示的参考医学图像数据（SI）; b）获取（S2）描述解剖体部分（2）和参考结构（3）的患者图像表示的患者医学图像数据; c）获取描述解剖体部分（2）的预定治疗位置的治疗位置数据，所述治疗位置数据应用于进行设想的医疗程序; d）获取描述标记装置（4）和参考结构（3）之间的预定空间关系的标记参考位置数据; e）获取描述所述标记装置（4）的实际位置的实际标记位置数据; f）基于参考医学图像数据和患者医学图像数据确定描述解剖体部分（2）和参考结构（3）之间的空间关系的身体部位参考位置数据; g）基于身体部位参考位置数据和标记参考位置数据确定描述解剖体部分（2）和标记装置（4）之间的空间关系的身体部位标记位置数据; h）基于所述治疗位置数据和所述标记参考位置数据和所述身体部位标记位置数据确定（S4），描述用于定位所述解剖体部分（2）的定位过程的定位控制数据。

6. 发明申请

WO2015127970A1 TRACKING SOFT TISSUE IN MEDICAL IMAGES 审中-公开
标题翻译：跟踪医学图像中的软组织
公开(公告)号：WO2015127970A1
公开(公告)日：2015-09-03
申请号：PCT/EP2014/053760
申请日：2014-02-26
申请人： BRAINLAB AG
发明人： BERLINGER, Kajetan , FROEHLICH, Stephan
IPC分类号： A61B6/00 , A61N5/10
CPC分类号： A61N5/1049 , A61B6/022 , A61B6/032 , A61B6/487 , A61B6/5223 , A61B6/5235 , A61B6/5264 , A61B6/5288 , A61B6/541 , A61N5/1067 , A61N5/1068 , A61N5/107 , A61N2005/1061 , G06F19/00 , G06K9/6202 , G06T7/0014 , G06T7/11 , G06T7/248 , G06T7/73 , G06T2207/10021 , G06T2207/10081 , G06T2207/10124 , G06T2207/20104 , G16H50/50
摘要： The present invention relates to a medical data processing method of determining the representation of an anatomical body part (2) of a patient (1) in a sequence of medical images, the anatomical body part (2) being subject to a vital movement of the patient (1), the method being constituted to be executed by a computer and comprising the following steps; e) acquiring advance medical image data comprising a time-related advance medical image comprising a representation of the anatomical body part (2) in a specific movement phase; f) acquiring current medical image data describing a sequence of current medical images, wherein the sequence comprises a specific current medical image comprising a representation of the anatomical body part (2) in the specific movement phase, and a tracking current medical image which is different from the specific current medical image and comprises a representation of the anatomical body part (2) in a tracking movement phase which is different from the specific movement phase; g) determining, based on the advance medical image data and the current medical image data, specific image subset data describing a specific image subset of the specific current medical image, the specific image subset comprising the representation of the anatomical body part (2); h) determining, based on the current medical image data and the image subset data, subset tracking data describing a tracked image subset in the tracking current medical image, the tracked image subset comprising the representation of the anatomical body part (2).
摘要翻译：本发明涉及一种医学数据处理方法，其以医学图像序列确定患者（1）的解剖体部分（2）的表示，所述解剖体部分（2）经受所述医学图像的重要运动患者（1），该方法被构造成由计算机执行并且包括以下步骤： e）获取包括在特定运动阶段包括解剖体部分（2）的表示的时间相关的先进医学图像的推进医学图像数据; f）获取描述当前医学图像序列的当前医学图像数据，其中该序列包括特定的当前医学图像，该特定的当前医学图像包括特定移动阶段中的解剖体部分（2）的表示，以及不同的跟踪当前医学图像并且包括解剖体部分（2）在与特定运动相位不同的跟踪运动阶段中的表示; g）基于提前医学图像数据和当前医学图像数据确定描述特定当前医学图像的特定图像子集的特定图像子集数据，所述特定图像子集包括解剖体部分（2）的表示; h）基于当前医学图像数据和图像子集数据确定描述跟踪当前医学图像中的跟踪图像子集的子集跟踪数据，所述跟踪图像子集包括解剖体部分（2）的表示。

7. 发明申请

WO2014048490A1 Isocentric Patient Rotation for Detection of the Position of a Moving Object 审中-公开
标题翻译：用于检测移动物体位置的异心患者旋转
公开(公告)号：WO2014048490A1
公开(公告)日：2014-04-03
申请号：PCT/EP2012/069205
申请日：2012-09-28
申请人： BRAINLAB AG
发明人： BERLINGER, Kajetan , FROEHLICH, Stephan
IPC分类号： A61N5/10 , G06T7/00 , G06T7/20 , G06T11/00 , A61B6/02 , A61B6/04
CPC分类号： G06T7/0012 , A61B6/025 , A61B6/0492 , A61B6/486 , A61B6/5235 , A61B6/5264 , A61B6/5288 , A61B6/541 , A61N5/1049 , A61N5/1065 , A61N5/1068 , A61N2005/1051 , A61N2005/1059 , G06T7/20 , G06T7/70 , G06T2207/10081 , G06T2207/10112
摘要： The invention relates to a method for determining the position of an object moving within a body, wherein the body is connected to markers, a movement signal is determined based on the measured movement of the markers, images are taken from the object using a camera or detector, wherein the camera or detector is moved with respect to the object, it is determined from which direction or range of angles or segment the most images corresponding to a predefined cycle of the movement signal are taken, and using at least some or all of the images of the segment containing the most images for a specified movement cycle, an image of the object is reconstructed.
摘要翻译：本发明涉及一种用于确定在身体内移动的物体的位置的方法，其中身体连接到标记，基于所测量的标记的移动来确定移动信号，使用照相机从物体中取出图像，检测器，其中相机或检测器相对于物体移动，确定从哪个方向或角度范围或者划分对应于移动信号的预定周期的最多图像，并且使用至少部分或全部包含指定移动周期的最多图像的片段的图像，对象的图像被重建。

8. 发明授权

EP3104781B1 FRAMELESS PRE-POSITIONING FOR RADIOSURGERY 有权转让
公开(公告)号：EP3104781B1
公开(公告)日：2018-10-03
申请号：EP14704366.5
申请日：2014-02-14
申请人： Brainlab AG
发明人： GRONBACH, Eva Maria , BERLINGER, Kajetan , FROEHLICH, Stephan
IPC分类号： A61B6/00 , A61N5/10
CPC分类号： A61B6/0492 , A61B6/032 , A61B6/0421 , A61B6/501 , A61B6/5211 , A61B6/547 , A61B90/14 , A61B90/39 , A61B2034/2055 , A61B2090/101 , A61B2090/364 , A61B2090/3937 , A61B2090/3983 , A61N5/1049 , A61N5/1069 , A61N2005/1061 , G01T7/005 , G06F19/00 , G06K9/00208 , G06K9/2054 , G06K9/2063 , G06K9/32 , G06K9/3216 , G06K9/6212 , G06K2009/2045 , G06K2009/3225 , G06K2009/3291 , G06T7/0014 , G06T7/74 , G06T2207/10081 , G06T2207/20221 , G06T2207/30004 , G06T2207/30204 , G06T2207/30208 , G06T2219/2004
摘要： The presently described method is directed to determining a way of positioning a patient before execution of a medical procedure involving irradiating the patient with ionizing treatment radiation based on comparing medical images of the patient with a pre-acquired medical image. The planning computed tomography is searched for an image of the reference stricture in order to determine the position of the patient relative to a patient support device. A retroreflective marker device, having a known and advantageously fixed position relative to the base plate, is detected by a navigation system operatively coupled to a motor of the support device. Based on the detected position of the marker device, the motor of the support device is activated to drive the patient into a desired position relative to beam direction along which the treatment radiation is to be issued towards the patient to execute the medical procedure.

9. 发明授权

EP3248652B1 NON-PLANAR TREATMENT BEAM CONTROL 有权
公开(公告)号：EP3248652B1
公开(公告)日：2019-09-04
申请号：EP17173193.8
申请日：2010-07-23
申请人： Brainlab AG
发明人： BERLINGER, Kajetan , FROEHLICH, Stephan , GUM, Franz
IPC分类号： A61N5/10

10. 发明授权

EP2739355B1 DOSE-OPTIMISED PATIENT POSITIONING FOR RADIOTHERAPY 有权转让
标题翻译：剂量优化的放射治疗患者定位
公开(公告)号：EP2739355B1
公开(公告)日：2017-05-10
申请号：EP11738244.0
申请日：2011-08-02
申请人： Brainlab AG
发明人： GUM, Franz , FROEHLICH, Stephan
IPC分类号： A61N5/10 , A61B6/03 , A61B6/00
CPC分类号： A61N5/1039 , A61B6/032 , A61B6/4085 , A61N5/1031 , A61N5/1048 , A61N5/1049 , A61N5/1077 , A61N2005/1061

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