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1. 发明申请

US20230114495A1 MICROFLUIDIC DEVICES COMPRISING ELECTROCHEMICAL SENSORS 有权
公开(公告)号：US20230114495A1
公开(公告)日：2023-04-13
申请号：US17991401
申请日：2022-11-21
申请人： Board of Regents, The University of Texas System
发明人： Hyejin MOON , Ali FARZBOD
IPC分类号： B01L3/00 , G01N27/416 , G01N27/403 , G01N27/30 , G01N27/333
摘要： An electrowetting-on-dielectric (EWOD) microfluidic device comprises at least one integrated electrochemical sensor, the electrochemical sensor comprising: a reference electrode; a sensing electrode; and an analyte-selective layer positioned over the sensing electrode. In some embodiments, the electrochemical sensor measures a concentration of an analyte in a fluid sample exposed to the electrochemical sensor based on a potential difference between the reference electrode and the sensing electrode. The first analyte and the second analyte can be selected from a group consisting of K+, Na+, Ca2+, Cl-, HCO3-, Mg2+, H+, Ba2+, Pb2+, Cu2+, I-, NH4+, (SO4)2-.

2. 发明申请

US20200070161A1 MICROFLUIDIC DEVICES COMPRISING ELECTROCHEMICAL SENSORS 审中-公开
公开(公告)号：US20200070161A1
公开(公告)日：2020-03-05
申请号：US16527859
申请日：2019-07-31
申请人： Board of Regents, The University of Texas System
发明人： Hyejin MOON , Ali Farzbod
IPC分类号： B01L3/00 , G01N27/416 , G01N27/403 , G01N27/30 , G01N27/333
摘要： An electrowetting-on-dielectric (EWOD) microfluidic device comprises at least one integrated electrochemical sensor, the electrochemical sensor comprising: a reference electrode; a sensing electrode; and an analyte-selective layer positioned over the sensing electrode. In some embodiments, the electrochemical sensor measures a concentration of an analyte in a fluid sample exposed to the electrochemical sensor based on a potential difference between the reference electrode and the sensing electrode. The first analyte and the second analyte can be selected from a group consisting of K+, Na+, Ca2+, Cl−, HCO3−, Mg2+, H+, Ba2+, Pb2+, Cu2+, I−, NH4+, (SO4)2−.

3. 发明申请

US20160175839A1 DIGITAL MICROFLUIDIC DEVICES AND METHODS OF DISPENSING AND SPLITTING DROPLETS IN DIGITAL MICROFLUIDIC DEVICES 审中-公开
标题翻译：数字微流体装置及其在数字微流体装置中的分配和分散滴液的方法
公开(公告)号：US20160175839A1
公开(公告)日：2016-06-23
申请号：US14976019
申请日：2015-12-21
申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人： Hyejin MOON , Jagath NIKAPITIYA
IPC分类号： B01L3/00
CPC分类号： B01L3/502792 , B01L7/52 , B01L2200/0605 , B01L2200/143 , B01L2300/0645 , B01L2300/0864 , B01L2300/161 , B01L2400/0427
摘要： In one aspect, digital microfluidic devices are described herein. In some embodiments, a device described herein comprises a droplet-dispensing component, the droplet-dispensing component comprising a first linear electrode segment, a second linear electrode segment, and a curved electrode segment connecting the first linear electrode segment and the second linear electrode segment. The curved electrode segment subtends an angle of about 90 degrees. Thus, in some embodiments, the droplet-dispensing component formed by the first linear electrode segment, the second linear electrode segment, and the curved electrode segment can be L-shaped or define an L-junction. Further, in some instances, the first and/or second linear electrode segment is formed from a plurality of contiguous electrodes. Additionally, the contiguous electrodes may be rectangular. The curved electrode segment of the droplet-dispensing component may also be formed from a plurality of electrodes, such as angled or sector-shaped electrodes.
摘要翻译：在一个方面，本文描述了数字微流体装置。在一些实施例中，本文所述的装置包括液滴分配组件，所述液滴分配组件包括第一线性电极段，第二线性电极段和连接第一线性电极段和第二线性电极段的弯曲电极段。弯曲的电极段对着大约90度的角度。因此，在一些实施例中，由第一线性电极段，第二线性电极段和弯曲电极段形成的液滴分配组件可以是L形或限定L结。此外，在一些情况下，第一和/或第二线性电极段由多个相邻的电极形成。另外，连续的电极可以是矩形的。液滴分配部件的弯曲电极段也可以由多个电极形成，例如角形或扇形电极。

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