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    • 8. 发明授权
    • Device for the treatment of biological fluid
    • 用于治疗生物液体的装置
    • US09095817B2
    • 2015-08-04
    • US13148476
    • 2010-02-11
    • Andreas Maurer
    • Andreas Maurer
    • C12M1/00C12M3/00C12M1/34C12M1/36C12M1/38B01D63/02A61M1/16A61M1/34B01D63/04
    • B01D63/026A61M1/16A61M1/1698A61M1/34A61M1/3403A61M2205/3331A61M2205/3334B01D63/043B01D2317/08B01D2319/06
    • The invention relates to a device (1) for the treatment of a biological fluid, comprising at least three chambers, wherein a first chamber (3), which is provided for receiving the biological fluid, and a second chamber (7), which is provided for receiving a gas, are separated from each other by at least one gas-permeable and liquid-impermeable membrane (9), said membrane (9) being used to transfer gas molecules between the first and second chambers (3, 7), and wherein the first chamber (3) and a third chamber (13) are separated from each other by at least one liquid-permeable membrane (15) which is used to transfer one or more components between the first and third chambers (3, 13). The second chamber (7) is delimited or enclosed by the at least one gas-permeable and liquid-impermeable membrane (9) and is located inside the first chamber (3) or is substantially enclosed by the first chamber (3) such that the biological fluid surrounds the second chamber (7). Similarly, the third chamber (13) is delimited or enclosed by the at least one liquid-permeable membrane (15) and is located inside the first chamber (3) or is substantially enclosed by the first chamber (3) such that the biological fluid surrounds the third chamber (13).
    • 本发明涉及一种用于治疗生物流体的装置(1),其包括至少三个室,其中设置用于接收生物流体的第一室(3)和第二室(7) 被提供用于接收气体,通过至少一个透气和液体不可渗透的膜(9)彼此分离,所述膜(9)用于在第一和第二室(3,7)之间转移气体分子, 并且其中所述第一室(3)和第三室(13)通过至少一个液体可渗透膜(15)彼此分开,所述液体可透过膜(15)用于在所述第一和第三室(3,13)之间转移一个或多个组分 )。 第二腔室(7)由至少一个透气和液体不可渗透膜(9)限定或封闭,并且位于第一腔室(3)的内部或基本上被第一腔室(3)封闭,使得 生物流体围绕第二腔室(7)。 类似地,第三室(13)由至少一个液体可渗透膜(15)界定或封闭,并且位于第一室(3)的内部或基本上由第一室(3)封闭,使得生物流体 围绕第三室(13)。
    • 9. 发明授权
    • Combination oxygenator and arterial filter device with a fiber bundle of continuously wound hollow fibers for treating blood in an extracorporeal blood circuit
    • 组合式氧合器和动脉过滤器装置,其具有用于治疗体外血液回路中的血液的连续缠绕中空纤维的纤维束
    • US08685319B2
    • 2014-04-01
    • US13097290
    • 2011-04-29
    • Robert OlsonJohn L. Knoll
    • Robert OlsonJohn L. Knoll
    • A61M1/00A61M37/00
    • A61M1/1698A61M1/3627B01D63/025B01D2313/38B01D2319/06
    • A combination oxygenator and arterial filter device for treating blood in an extracorporeal blood circuit. The device includes a housing maintaining a core and a fiber bundle. The fiber bundle is formed by a plurality of hollow fibers continuously helically wound about the core to form layers of level wound fibers. The layers combine to define an oxygenator region and a radially outward depth filter region. A minimum gap spacing between fibers of the oxygenator region layers is greater than a minimum gap spacing of the depth filter region layers. The fiber bundle can function as a blood oxygenator and exhibits a filtration efficiency of not less than 92% in filtering particles having a particle size of about 45 microns. An oxygenator with integrated arterial filtering capability is provided that minimally impacts the extracorporeal blood circuit prime volume.
    • 用于治疗体外血液回路中的血液的组合氧合器和动脉过滤装置。 该装置包括保持芯部和纤维束的壳体。 纤维束由围绕芯连续螺旋缠绕的多个中空纤维形成,以形成水平缠绕纤维层。 这些层组合以限定氧合器区域和径向向外深度过滤器区域。 氧合器区域层的纤维之间的最小间隙间隔大于深度过滤器区域层的最小间隙间距。 纤维束可用作血液充氧器,并且在粒径约45微米的过滤颗粒中显示出不低于92%的过滤效率。 提供具有综合动脉过滤功能的充氧器,其最小程度地影响体外血液回路原始体积。