氧四环素相关的专利数据

序号	专利名	申请号	申请日	公开（公告）号	公开（公告）日	发明人
81	新颖的7-(取代)-8-(取代)-9-[(取代的甘氨酰)酰氨基]-6-去甲基-6-去氧四环素	CN93107916.0	1993-07-01	CN1033087C	1996-10-23	苏费恩; V·J·李; J·J·赫拉夫卡; R·T·泰斯塔
本发明提供了下式化合物：其中R，R3，R4，X和W如说明书中所定义。这些化合物作为抗生素是有用的。
82	新颖的7-(取代)-8-(取代)-9-[(取代的甘氨酰)酰氨基]-6-去甲基-6-去氧四环素	CN93107916.0	1993-07-01	CN1087626A	1994-06-08	苏费恩; V·J·李; J·J·赫拉夫卡; R·T·泰斯塔
本发明提供了式I化合物。其中R，R3，R4，X和W如说明书中所定义。这些化合物作为抗生素是有用的。
83	7－(取代－)－8－(取代)－9－(取代的氨基)－6－去甲基－6－去氧四环素及其制备方法、组合物和用途	CN93109819.X	1993-08-13	CN1048719C	2000-01-26	苏费恩; V·J·李; J·J·赫拉夫卡; R·T·泰斯塔
本发明提供了具下式结构的化合物，其中X，R及R1均如说明书中所定义。这些化合物作为抗生素是有用的。
84	6-deoxytetracyclines	US75118058	1958-07-28	US3160661A	1964-12-08	DANIEL MCCORMICK JERRY ROBERT

85	6 脫氧四環素之製造	TW06210809	1973-06-06	TW016130B	1974-06-01	意凡維拉克斯

86	Nu-ethyloxytetracycline	US42821765	1965-01-26	US3394178A	1968-07-23	DULANEY EUGENE L; IRVING PUTTER

87	12alpha-deoxytetracycline oxidation process	US20834362	1962-07-09	US3188348A	1965-06-08	KENNETH BUTLER; WOODWARD ROBERT B; GORDON PHILIP N

88	Substituted 6-deoxytetracyclines and 6-demethyl-6-deoxytetracyclines	US10294361	1961-04-14	US3219671A	1965-11-23	HLAVKA JOSEPH J

89	12alpha-deoxyanhydrotetracyclines	US69301857	1957-10-29	US2922817A	1960-01-26	ARTHUR GREEN

90	–6–去氧四環素之製造法	TW06312026	1974-09-27	TW025184B	1979-05-01	吉諾哥帝

91	6-데옥시테트라싸이클린의 제조방법	KR1019740002938	1974-06-29	KR100007876B1	1980-03-28	토마스아아서모리스쥬니어

92	氧四環素之新奇高產量製造法	TW010409	1964-06-27	TW002884B	1966-07-01	吉拉羅法布利齊歐博士; 吉歐巴尼歐利吉馬; 意樂銑利歐意西利

93	Process for the photooxygenation of anhydrotetracyclines	US23025262	1962-10-12	US3269929A	1966-08-30	VON WITTENAU MANFRED SCHACH

94	α-6-데옥시테트라싸이클린의 제조방법	KR1019750002807	1975-12-20	KR100008931B1	1980-11-27	허어만호오불

95	Process for the preparatin of .alpha.-6-deoxytetracyclines	US772923	1977-02-28	US4207258A	1980-06-10	Renato Broggi; Gino Cotti
A process is provided for preparing alpha-6-deoxytetracyclines depicted by the formula: ##STR1## wherein Y is H, F, Cl, Br or I; and R is H, OH or --O--CO--(C.sub.1-6 alkyl);which comprises: contacting a 6-demethyl-6-deoxy-6-methylene tetracycline or salt thereof having the formula ##STR2## in which Y and R are as given above, with hydrogen at a temperature of between 15.degree. C. and 80.degree. C. in the presence of a catalyst soluble in a polar solvent, said catalyst being a complex of rhodium with electron donor ligands of a tertiary phosphine selected from the group consisting of triphenylphosphine, tributylphosphine, triethylphosphine, diethylphenylphosphine and diphenylethylphosphine and said polar solvent being a mono- or polyhydric alcohol with from 1 to 4 carbon atoms, N,N-dimethylformamide, N,N-dimethylacetamide, dioxan, tetrahydrofuran, methoxyethanol, ethoxyethanol, acetonitrile or pyridine.
96	Tetracyclo epoxy ether monomer and compositions	US3472796D	1960-05-31	US3472796A	1969-10-14	TINSLEY SAMUEL W; STARCHER PAUL; MCGARY CHARLES W JR; PATRICK CHARLES T JR

97	α-6-데옥시-테트라싸이클린의 제조방법	KR1019840004933	1984-08-16	KR100024400B1	1987-10-29	필립로날드페이지

98	Aqueous calcium dioxytetracycline antibiotic composition	US57500456	1956-03-30	US2903395A	1959-09-08	SALIVAR CHARLES J

99	α-6-데옥시 테트라싸이클린류의 제조방법	KR1019860010792	1986-12-16	KR100033762B1	1990-06-15	요아오에메리꼬발락스; 필립로날드페이지

100	α-6-데옥시 테트라싸이클린류의 제조방법	KR1019860010792	1986-12-16	KR1019900000888B1	1990-02-17	요아오에메리꼬발락스; 필립로날드페이지
Alpha-6-deoxytetracyclines are prepd. from 6-deoxy-6-dimethyl -6- methylenetetracycline or 11a-chloro-6-deoxy-6-demethyl- 6methylenetetracycline in the presence of triphenylphosphine or a catalyst of formula (I). In the formula, Z means capability of generating bimolecular or trimolecular compound; R'1 is phenyl; benzenesulfonyl or hydrogen; R'2, R'3, R'4 are hydrogen. The alpha- 6-deoxytetracyclines are useful as antiotics.

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