专利检索_...有次磺酸基的硫原子连接在六元芳环以外的其他环的碳原子上专利检索_...有次磺酸基的硫原子连接在六元芳环以外的其他环的碳原子上专利检索查询

序号	专利名	申请号	申请日	公开（公告）号	公开（公告）日	发明人
1	一种制备环已基次磺酰氯的方法	CN201510950308.7	2015-12-18	CN106892846A	2017-06-27	赵福宝
本发明公开了一种制备环已基次磺酰氯的方法。采用二硫代二环已烷在煤油作为溶剂存在下，通入氯气反应，反应温度20-40℃，反应压力常压，反应时间为20～40分钟，反应液中环已基次磺酰氯含量达到96%以上。
2	PRODUCTION OF 4-FLUOROTHIOPHENOL	JP16705095	1995-06-09	JPH083130A	1996-01-09	HERUMUUTO FUIIGE; FUERUDEINANDO HAGEDORUN; BORUFUGANGU AIMAN; OTSUTOO NOINAA; HERUBERUTO MIYURAA

3		ES95108486	1995-06-02	ES2105816T3	1997-10-16	FIEGE HELMUT DR; HAGEDORN FERDINAND DR; EYMANN WOLFGANG DR; NEUNER OTTO DR; MULLER HERBERT DR
4-Fluorothiophenol is obtained in outstanding purifies and yields if 4-fluorobenzenesulphonyl chloride is reacted with sodium hydrogen sulphite solution to give a solution of sodium 4-fluorobenzenesulphinate, this solution is reduced with sulphur dioxide to give 4,4'-difluorodiphenyl disulphide and finally this is reacted with sodium borohydride in a water-miscible inert organic solvent to give 4-fluorothiophenol (sodium salt). Free 4-fluorothiophenol can be isolated from the sodium salt solution by acidification.
4		DE59500629	1995-06-02	DE59500629D1	1997-10-16	FIEGE HELMUT DR; HAGEDORN FERDINAND DR; EYMANN WOLFGANG DR; NEUNER OTTO DR; MUELLER HERBERT DR
4-Fluorothiophenol is obtained in outstanding purifies and yields if 4-fluorobenzenesulphonyl chloride is reacted with sodium hydrogen sulphite solution to give a solution of sodium 4-fluorobenzenesulphinate, this solution is reduced with sulphur dioxide to give 4,4'-difluorodiphenyl disulphide and finally this is reacted with sodium borohydride in a water-miscible inert organic solvent to give 4-fluorothiophenol (sodium salt). Free 4-fluorothiophenol can be isolated from the sodium salt solution by acidification.
5	4,4-(disubstituted) cyclohexan-1-ol monomers and related compounds	IL11649095	1995-12-21	IL116490D0	1996-03-31

6	Surfactants derived from 2-(2-hydroxyphenyl) benzenesulfinate	AU3010799	1999-03-18	AU3010799A	1999-10-11	LANGE ELAINE A; LIN QUN; NIELSEN KURT R; DOOYEMA CHRISTOPHER C
The present invention relates to compounds having utility as surfactants which are derived from intermediates produced in petroleum biodesulfurization processes. The compounds of the invention include acyloxybiphenylsulfinates, acyloxybiphenylsulfonates, alkyl sulfinatobiphenyl ethers and alkyl sulfonatobiphenyl ethers. The invention also provides methods of producing these compounds.
7	PHARMACEUTICAL COMPOUNDS	CA2218782	1997-10-17	CA2218782A1	1998-04-18	HARRIS JOHN RICHARD; CLARK BARRY PETER
Pharmaceutical compounds of the formula (see fig. I) in which R1 is Y or Y-C1-6 alkyl, where Y is carboxy, tetrazo yl, -SO2H, -SO3H, -OSO3H, -CONHOH, or -P(OH)OR', -PO(OH)OR', -OP(OH)OR' or -OPO(OH)OR' where R' is hydrogen, C1-6 alkyl, C2-6 alkenyl or optionally substituted phenyl-C1-6 alkyl, R2, R3 and R4 are each hydrogen, hydroxyl, halo, carboxy, C1-6 alkyl, carboxy-C1-6 alkyl, optionally substituted phenyl, optionally substituted phenyl-C1-6 alkyl or C2-6 alkenyl, X and Z are each hydrogen, C1-6 alkyl, C3-7 cycloalkyl, optionally substituted phenyl, optionally substituted phenyl-C1-6 alkyl, optionally substituted naphthylmethyl, optionally substituted anthracenylmethyl, (see fig. I) or (see fig. II) where R'' and R''' are optionally substituted phenyl, or (see fig. III) where n is 0 or 1 to 3, Q is -O-, -NH-, -S-, -SO-, -SO2-, -CH2-, -CH=CH-, -CH2S-, -CH2O-, -CH2CH2- or -CONR'''' where R'''' is hydrogen or C1-6 alkyl, and R5, R6, R7, R8 and R9 are each hydrogen, halo, C1-6 alkyl, C1-6 alkyloxy or hydroxy; provided that one of X and Z is hydrogen, or both of X and Z are hydrogen; or a salt or ester thereof.
8		FR1006341D	1947-12-20	FR1006341A	1952-04-22

9	4-fluoro - thiophenol of production method	JP16705095	1995-06-09	JP3832599B2	2006-10-11	オツトー・ノイナー; フエルデイナンド・ハゲドルン; ヘルベルト・ミユラー; ヘルムート・フイーゲ; ボルフガング・アイマン

10	PHARMACEUTICAL COMPOUND	JP28574397	1997-10-17	JPH10120635A	1998-05-12	CLARK BARRY PETER; JOHN RICHARD HARRIS
PROBLEM TO BE SOLVED: To obtain the subject new compound useful for the treatment of diseases of the central nervous system and as an antipsychotic agent, an analgesic, etc. SOLUTION: This compound is expressed by formula I [R<1> is Y or Y-(1-6C alkyl) (Y is carboxy, tetrazolyl, etc.); R<2> , R<3> and R<4> are each H, hydroxy, etc.; X and Z are each H, a 1-6C alkyl, etc.] or their salts or esters, e.g. 2-amino-2-(3- cis-carboxycyclobutyl)-3-(9-xanthyl)propionic acid. The compound of formula I is produced by hydrolyzing a compound of formula II. The hydrolysis reaction is carried out in a proper solvent (e.g. water) at a high temperature (50-200 deg.C) in the presence of an acid (e.g. hydrochloric acid) or a base (e.g. NaOH). The starting compound of formula II is produced by reacting a compound of formula III with KCN and (NH4 )2 CO3 in a hydrated ethanol under a Bucherer-Bergs reaction condition at 30-120 deg.C.
11	2-amino-2-(3-substituted cyclobutyl) acetic acid derivatives	US954675	1997-10-17	US6054448A	2000-04-25	Barry Peter Clark; John Richard Harris
Compounds of the formula ##STR1## in which R.sup.1 is Y or Y--C.sub.1-6 alkyl, where Y is carboxy, tetrazolyl, --SO.sub.2 H, --SO.sub.3 H, --OSO.sub.3 H, --CONHOH, or --P(OH)OR', --PO(OH)OR', --OP(OH)OR' or --OPO(OH)OR' where R' is hydrogen, C.sub.1-6 alkyl, C.sub.2-6 alkenyl or optionally substituted phenyl-C.sub.1-6 alkyl,and R.sup.2, R.sup.3, R.sup.4, X and Z are as defined in the specification, possess affinity for metabotropic glutamate receptors and are useful in the treatment of disorders of the central nervous system.
12	One vessel stereoselective glycosylation of purines and pyrimidines	US970691	1992-11-04	US5602245A	1997-02-11	Julie Wurster; Dennis C. Liotta; Jianying Wang; Lawrence J. Wilson
A process for the preparation of 2',3' dideoxynucleosides, 2'-deoxynucleosides, and 2',3'-dideoxy-2',3'-didehydronucleosides is provided that includes the synchronous addition of a stereoselecting moiety (a directing group) and a protected purine or pyrimidine base to 5-(S)-6-(protected-oxy)-4,5-dihydrofuran in the presence of a Lewis acid. This one vessel reaction eliminates the need to separately prepare and purify a 2'-substituted ribose derivative that in a second step is condensed with a purine or pyrimidine base. The process can be easily modified to increase the stereoselectivity of formation of the .beta.-anomeric nucleoside as necessary.
13	CYCLOHEXANOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM	IL11649095	1995-12-21	IL116490A	2001-08-08

14	Pharmaceutical compounds	GB9621789	1996-10-18	GB9621789D0	1996-12-11
Pharmaceutical compounds of the formula in which R<1> is Y or Y-C1-6 alkyl, where Y is carboxy, tetrazolyl, -SO2H, -SO3H, -OSO3H, -CONHOH, or -P(OH)OR', -PO(OH)OR'. -OP(OH)OR' or -OPO(OH)OR' where R' is hydrogen, C1-6 alkyl, C2-6 alkenyl or optionally substituted phenyl-C1-6 alkyl, R<2>, R<3> and R<4> are each hydrogen, hydroxyl, halo, carboxy, C1-6 alkyl, carboxy-C1-6 alkyl, optionally substituted phenyl, optionally substituted phenyl-C1-6 alkyl or C2-6 alkenyl, X and Z are each hydrogen, C1-6 alkyl, C3-7 cycloalkyl, optionally substituted phenyl, optionally substituted phenyl-C1-6 alkyl, optionally substituted naphthylmethyl, optionally substituted anthracenylmethyl, where R'' and R''' are optionally substituted phenyl, or where n is 0 or 1 to 3, Q is -O-, -NH-, -S-, -SO-, -SO2-, -CH2-, -CH=CH-, -CH2S-, -CH2O-, -CH2CH2- or -CONR'''' where R'''' is hydrogen or C1-6 alkyl, and R<5>, R<6>, R<7>, R<8> and R<9> are each hydrogen, halo, C1-6 alkyl, C1-6 alkyloxy or hydroxy; provided that one of X and Z is hydrogen, or both of X and Z are hydrogen; or a salt or ester thereof. R'
15		DE4420777	1994-06-15	DE4420777A1	1995-12-21	FIEGE HELMUT DIPL CHEM DR; HAGEDORN FERDINAND DIPL CHEM D; EYMANN WOLFGANG DIPL CHEM DR; NEUNER OTTO DIPL CHEM DR; MUELLER HERBERT DIPL CHEM DR
4-Fluorothiophenol is obtained in outstanding purifies and yields if 4-fluorobenzenesulphonyl chloride is reacted with sodium hydrogen sulphite solution to give a solution of sodium 4-fluorobenzenesulphinate, this solution is reduced with sulphur dioxide to give 4,4'-difluorodiphenyl disulphide and finally this is reacted with sodium borohydride in a water-miscible inert organic solvent to give 4-fluorothiophenol (sodium salt). Free 4-fluorothiophenol can be isolated from the sodium salt solution by acidification.
16		DE4227896	1992-08-22	DE4227896A1	1994-02-24	MISSLITZ ULF DR; MEYER NORBERT DR; KAST JUERGEN DR; KOLASSA DIETER DR; WESTPHALEN KARL-OTTO DR; GERBER MATTHIAS DR; KARDORFF UWE DR; WALTER HELMUT DR
Cyclohexenonoxime ethers have formula (I) in which the substituents have the following meaning: R<1> stands for alkyl; R<2> for alkyl, halogen alkyl, alkenyl, halogen alkenyl, alkinyl or halogen alkinyl; -A<1>-O-N=CH-Ph or A<2>-W, in which A<1> stands for possibly substituted C2-C4-alkylen, Ph stands for possibly substituted phenyl, A<2> stands for possibly substituted alkylen, alkenylen or alkinylen, or for possibly substituted alkylenoxy, alkenylenoxy or alkylenoxyalkylen, W stands for possibly substituted phenyl, pyridyl or thienyl; R<3> stands for substituted alkyl, possibly substituted cycloalkyl or cycloalkenyl, a possibly substituted 5-membered saturated heterocycle which may contain besides carbon ring members one or two oxygen and/or sulphur atoms, a possibly substituted 6 or 7-membered saturated or mono- or double-unsaturated heterocycle which may contain besides carbon ring members one or two oxygen and/or sulphur atoms, a possibly substituted 5-membered heteroaromate, which contains besides carbon ring members one or two nitrogen atoms and one oxygen or one sulphur atom; possibly substituted phenyl or pyridyl; R<4> stands for hydrogen, alkyl, halogen alkyl, alkenyl, halogen alkenyl, alkinyl, halogen alkinyl, alkyl carbonyl or halogen alkyl carbonyl, possibly substituted benzoyl, -S(=O)2-R; -P(=O)(OR)(OR) or - SiRRR, in which R, R, R, R and R represent independently from each other C1-C10-alkyl, C1-C10-halogen alkyl or possibly substituted phenyl. Also disclosed are their preparation, agents containing the same and their use.
17	Surfactants derived from 2-(2-hydroxyphenyl)benzenesulfinate and alkyl-substituted derivatives	US44272	1998-03-19	US5973195A	1999-10-26	Elaine A. Lange; Qun Lin; Kurt R. Nielsen; Christopher C. Dooyema
The present invention relates to compounds having utility as surfactants which are derived from intermediates produced in petroleum biodesulfurization processes. The compounds of the invention include acyloxybiphenylsulfinates, acyloxybiphenylsulfonates, alkyl sulfinatobiphenyl ethers and alkyl sulfonatobiphenyl ethers. The invention also provides methods of producing these compounds.
18	Process for the preparation of 4-fluorothiophenol	US456839	1995-06-01	US5659088A	1997-08-19	Helmut Fiege; Ferdinand Hagedorn; Wolfgang Eymann; Otto Neuner; Herbert Muller
4-Fluorothiophenol is obtained in outstanding purifies and yields if 4-fluorobenzenesulphonyl chloride is reacted with sodium hydrogen sulphite solution to give a solution of sodium 4-fluorobenzenesulphinate, this solution is reduced with sulphur dioxide to give 4,4'-difluorodiphenyl disulphide and finally this is reacted with sodium borohydride in a water-miscible inert organic solvent to give 4-fluorothiophenol (sodium salt). Free 4-fluorothiophenol can be isolated from the sodium salt solution by acidification.
19	Verfahren zur Herstellung von 4-Fluorthiophenol	EP95108486.2	1995-06-02	EP0687671B1	1997-09-10	Fiege, Helmut, Dr.; Hagedorn, Ferdinand, Dr.; Eymann, Wolfgang, Dr.; Neuner, Otto, Dr.; Müller, Herbert, Dr.

20	Verfahren zur Herstellung von 4-Fluorthiophenol	EP95108486.2	1995-06-02	EP0687671A1	1995-12-20	Fiege, Helmut, Dr.; Hagedorn, Ferdinand, Dr.; Eymann, Wolfgang, Dr.; Neuner, Otto, Dr.; Müller, Herbert, Dr.
4-Fluorthiophenol wird in hervorragenden Reinheiten und Ausbeuten erhalten, wenn man 4-Fluorbenzolsulfochlorid mit Natriumhydrogensulfitlösung zu einer 4-Fluorbenzolsulfinsäure-Na-Salzlösung umsetzt, diese Lösung mit Schwefeldioxid zu 4,4'-Difluordiphenyldisulfid reduziert und schließlich dieses mit Natriumborhydrid in einem mit Wasser mischbaren inerten organischen Lösungsmittel zu 4-Fluorthiophenol (Na-Salz) umsetzt. Aus der Natriumsalz-Lösung kann man freies 4-Fluorthiophenol durch Ansäuern gewinnen.

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