Document Document Title
US09970264B2 Downhole actuation apparatus and associated methods
A downhole actuating apparatus for actuating downhole. The apparatus is actuatable at the downhole location at, upon or during one or more particular cycle/s selectable from a sequence of cycles according to a predetermined selection. The downhole actuation comprises the release of at least one flowable object from the downhole location. The apparatus releases the at least one flowable object from the downhole location at, upon or during the particular cycle selectable from the sequence of cycles.
US09970249B2 Degradable anchor device with granular material
In one aspect, an anchoring device is disclosed, including: a degradable substrate with a first hardness; and a granular gripping material associated with the outer extent of the degradable substrate, wherein the granular gripping material has a second hardness greater than the first hardness. In certain embodiments, the granular gripping material is degradable. In another aspect, a method to anchor a downhole device is disclosed, including: providing a degradable substrate with a first hardness; and applying a granular gripping material to the outer extent of the degradable substrate, wherein the granular gripping material has a second hardness greater than the first hardness.
US09970247B2 MPD-capable flow spools
This disclosure includes flow spool riser segment assemblies that are suitable for managed pressure drilling (MPD) and that can be lowered (e.g., when connected to other riser segment assemblies) through a rotary of a drilling rig. Some embodiments are configured to have portions of the flow spool connected (e.g., without welding) below the rotary.
US09970246B2 Triggered heating of wellbore fluids by carbon nanomaterials
A method of triggering heating within a subterranean formation, that includes introducting a wellbore fluid containing a dispersed carbon nanomaterial into a wellbore through the subterranean formation; lowering a microwave or ultraviolet radiation source into the wellbore; and irradiating the wellbore with microwave or ultraviolet radiation, thereby increasing the temperature of the wellbore fluid and/or wellbore is disclosed.
US09970240B2 Polycrystalline diamond composite compact
A polycrystalline diamond (PCD) composite compact element comprising a PCD structure bonded to a cemented carbide substrate, in which at least a peripheral region of the substrate comprises cemented carbide material having a mean free path (MFP) characteristic of at least about 0.1 microns and at most about 0.7 microns; and an elastic limit of at least about 1.9 GPa.
US09970238B2 Method in putting together of a down-the-hole drilling apparatus and a down-the-hole drilling apparatus
A method for assembling a down-the-hole drilling apparatus including a drilling device including a casing and a drilling unit arranged during drilling in connection with the casing. The drilling unit includes a drilling head including a drilling arrangement including a first drilling member for drilling a center hole and a second drilling member for reaming the center hole. The drilling members are mutually power transmittingly coupled during drilling to cooperate for rotational, feeding and/or hammering, and removably coupled to enable removal of the first drilling member from a hole. The casing is arranged to be pulled into the hole through a shoulder arranged at an end of the casing. At an opposite end of the drilling arrangement with respect to a drilling surface, is arranged a skirt including a radial internal shoulder for pulling the casing into the hole by cooperation of the internal shoulder and an external shoulder at the end of the casing.
US09970227B2 Smart opening system and a method of operating a smart opening system
A smart opening system is provided. The smart opening system includes a vehicle defining an aperture, a door coupled to the vehicle to assume a first position at which the aperture is closed and multiple second positions at which the aperture is open and to move between the first and second positions, a sensor disposed to sense obstructions surrounding the vehicle and a processing element coupled to the sensor and configured to determine whether any of the obstructions are within a range of motion of the door.
US09970218B1 Remote controlled retractable leg restraint device
A remote controlled retractable leg iron device provides a restraint device which can be used by police or any other authority to maintain control of persons while in transport. The device is remote controlled so an operator can control the wearer from a distance. The cuffs are secured to the legs of the wearer and are attached to the housing unit by a cable which retracts into the housing unit. In a normal operation mode the cable freely extends and retracts so that the wearer can walk or move with little resistance. In an emergency mode, the device retracts the wire cable into the housing unit so that the wearer's legs are restrained tightly together—removing the lack of resistance and thus stopping the wearer's motion. The emergency mode is activated using the remote control.
US09970216B1 Security door features
A security door system includes a door jamb, a door, and a deadbolt mechanism. The door jamb includes a soffit and an aperture defined in the soffit. The deadbolt mechanism is mounted to a surface of the door and out of a plane of the door such that a deadbolt of the deadbolt mechanism is operable to project into the aperture in a locked position. In various implementations, the deadbolt mechanism may be mounted to the surface of the door by attachment members such as bolts that extend through attachment member apertures in the door. Shock absorbent material may be variously positioned around the attachment members in the attachment member apertures and may absorb at least some shock from a force applied to the deadbolt mechanism.
US09970215B2 Actuating assembly for a latching system
An actuating assembly of a locking system (200) to operate a displaceable component of a latching system (210), includes: (i) a first member (24) which is connected or connectable to the displaceable component of the latching system (210); (ii) a second member (26), the first and second members (24, 26) being disconnectably connectable to each other, with the first and second members (24, 26) being in an inoperative configuration when they are disconnected from each other such that the second member (26) is displaceable independently of the first member (24), and the first and second members (24, 26) being in an operative configuration when they are connected to each other such that displacement of the second member (26) causes the first member (24) to be displaced; (iii) a first actuating sub-assembly (46) including a first key receiver (230) for receiving a non-mechanical first key in the form of a predetermined electromagnetic signal transmitted via a cellular telecommunications network from the communications facility (224) of a monitoring facility (227) to an electronic controller (228); (iv) a second actuating sub-assembly (52) which is operable by a second key (226), the second actuating sub-assembly (52) being operably connected to the second member (26) and being configured, when actuated by the second key (226), to cause the second member (26) to be displaced, thereby to cause the first member (24) to be displaced when the first and second members (24, 26) are in their operative configuration; and (v) a timer for determining the time from receipt of a first key by the first actuating sub-assembly (46), wherein the first actuating subassembly (46) is configured, upon: (i) receipt of the first key, to cause the first and second members (24, 26) to assume their operative configuration; and (ii) elapse of a preset time stored in a storage means (236) measured by the timer from receipt of a first key by the first actuating sub-assembly (46), to cause the first and second members (24, 26) to assume their inoperative configuration.
US09970214B2 Door or other closable panel with lock-actuating linkage
A door or window arrangement has a panel movable relative to an opening bounded by a frame so as to close against a strike jamb or move away from it. A locking element moves between a locked state in which it engages between the panel and the strike jamb to prevent separation of the panel from the strike jamb and a released state in which the panel can be separated from the strike jamb. A linkage is displaced by a terminal part of a closing motion of the panel so that completion of the closing motion can only occur when the locking element assumes its locked state. Preferably, the linkage is deployed so that force applied to displace the panel through the terminal part of the closing motion results in a force applied to the locking element to displace it towards its locked state.
US09970212B2 Shade and clamp device
Disclosed herein are device and system for providing shade including: a) a deformable screen assembly having a border about its edge, the screen assembly including: i) a support frame defining the edge of the screen assembly, and ii) a screen component having at least two apertures for receiving an adjustable arm, the apertures being contained within the screen assembly edge; and; b) an adjustable arm. Also disclosed herein are devices for clamping an object.
US09970209B2 Method and apparatus for communicating over a two-wire power cable between an external power supply and a self-propelled robotic swimming pool cleaner
A robotic pool cleaner includes a housing with an interior chamber. A filter within the interior chamber filters water drawn through a water inlet provided in a bottom portion of the housing. Filtered water is discharged through a discharge port provided in a upper portion of the housing. Rotatably-mounted supports attached to the housing support and guide the cleaner on the pool surface. An electric motor mounted in the chamber is configured to move the cleaner on a pool surface. A pool cleaner controller electrically connected to the electric motor controls movement of the cleaner and receives communication signals transmitted by a remote power supply over a two-wire electric cable having first and second conductors. The pool cleaner controller is configured to provide uninterrupted electric power to the electric motor while the pool cleaner controller also receives pulsed communication signal from the remote power supply over the two-wire cable.
US09970196B1 Stand-off bracket
This invention relates to a bracket including a barrel with a screw-threaded recess, a disk-shaped cap and a fastener that is receivable in the recess. The fastener is configured to attached the cap to the barrel in a spaced apart arrangement, when the fastener is received in the recess. The barrel comprises a body of polymeric material, a metal bush embedded in the body and defining the screw threaded recess, and a metal sleeve that extends partially around the periphery of the body.
US09970193B1 System and method for the construction of dwellings
The present disclosure provides a building construction system and method for preventing the moisture of soil from reaching floor or foundation of the building. The method includes steps of digging in soil for piles to a depth determined based on soil nature, raising plurality of concrete piles from the depth to a height above the ground/grade, connecting the piles using steel beams and placing transversal members between steel beams allowing for blocks to be placed between the transversal members to define a surface wherein concrete can be poured creating a raised foundation floor.
US09970190B2 Rotary joint with actuator, framework construction kit and framework with rotary joints
A rotary joint includes a socket rod having a socket rod flange with a basically spheroid con-cave bearing surface at a first end, a housing nut encircling the socket rod and having a threaded wrenching head, a ball rod having a basically spheroid convex bearing surface and threaded side walls around the convex bearing surface, and a joint actuator configured to actuate relative movement of the socket rod flange and the ball rod. A diameter of the threaded side walls of the ball rod corresponds to a diameter of the threaded wrenching head of the housing nut.
US09970175B2 Anchor pier for manufactured building
An anchor pier for supporting a manufactured building, in which the anchor pier includes having a shaft with a connector and a helical flight proximate a driving tip, with a brace member attached to the connector and to the manufactured building with a connector, to transfer loading between the manufactured building and the ground. A method of supporting a manufactured building is disclosed.
US09970173B2 Device for deep driving of tubes having a large diameter
A tubing device is operatively connectable to an excavation machine. The tubing device comprises a base frame, at least one guiding tower operatively connected to the base frame, and a tube operating unit, operatively connected to the guiding tower. The tube operating unit is slidable along the guiding tower and is provided with engaging means capable of both selectively holding a tube segment, and of transmitting a rotary motion and an axial sliding movement to such a tube segment so as to allow the progressive driving in the ground and subsequent extraction from the ground.
US09970166B2 Concrete bridge system and related methods
A concrete culvert assembly includes multiple culvert units forming multiple side-by-side channels. One or more of the side-by-side channels have an interior side that is substantially vertical and an exterior side that is outwardly angled from top to bottom.
US09970162B2 Textile run and use thereof
A textile run with a slide surface (1, 51) consisting of looped fabric, the looped fabric comprising loops (4, 54) which are formed of warp threads by weaving or of pile threads by tufting and have a height (3, 53) of between at least 3 mm and at most 10 mm, 100 to 950 loops being disposed over an area of 1 dm 2. The invention further concerns the use of the textile run.
US09970157B2 Reducing content of hexenuronic acids in cellulosic pulp
The present invention provides an enzymatic method for reducing the content of hexenuronic acids in a chemical cellulosic pulp and/or improvement of the brightness of cellulosic pulp using haloperoxidase.
US09970152B2 Method for functionalizing a solid material surface with self assembling or self aggregating cyclodextrins and products thereof
The present invention relates to a method for functionalizing a solid material surface with self assembling or self aggregating cyclodextrins, said method comprising the steps of: providing an adsorption solution comprising at least one modified cyclodextrin and at least one solvent; and contacting a solid material surface with the adsorption solution.
US09970149B2 Detergent dosing controller
A detergent dosing controller that is convenient to use and has better effect is disclosed herein. One side of the main passage is a water inlet (101), another side of the main passage is outlet (102) connecting to liquid inlet of washing bucket, and valves A(2), B(3), C(4), D(5), pump (6) and nozzle (7) are equipped. The inlet of valve A connects to the bypass orifice A(a) of the main passage, inlet of valve B connects to liquid storage tank of detergent A, outlets of valve A and valve B connect to inlet of valve C, inlet of valve D connects to liquid storage tank of detergent B, outlets of valve C and valve D connect to inlet of the pump, outlet of the pump connects to bypass orifice B(b) of the main passage, and for the relative location of bypass orifices A and B of main passage, bypass orifice A is relatively close to the inlet of main passage, bypass orifice B is relatively close to the outlet of main passage, the nozzle connects to main passage by concatenation and between bypass orifices A and B. The invention is applicable to the dosing of detergent for electric washing equipments.
US09970146B2 Wall-mounted drum type washing machine
A wall-mounted drum type washing machine includes a rear panel mounted on a wall surface; a tub containing washing water, supported by the rear panel; a front panel on the tub; a cover unit covering the front panel; and a detachable detergent box inserted through the cover unit and into the front panel.
US09970141B2 Apparatus and method for washing an elongate textile article
Apparatus and method for washing an elongate textile article of extended indeterminate length utilizes a containment structure defining a channel extending upwardly from a lower end to an upper end thereof, with a plurality of undulations spaced-apart from one another within the channel between the lower and upper ends thereof, each undulation extending transversely across the channel. A portion of the lengthwise extent of the traveling textile article is advanced transiently within the channel upwardly from the lower end to the upward end and across the undulations, while a substantially continuous supply of cleansing liquid enters the channel at the upper end to flow downwardly against the upwardly traveling portion of the textile article for cleansing thereof.
US09970139B2 Microfibrous product and the use thereof for the preparation of covers and cases
The invention refers to a process for the preparation of a microfibrous non-woven fabric based on polyester or polyamide microfibers immersed in a polyurethane matrix, and having a thickness equal to or less than 0.65 mm, a flat or slightly mottled appearance and a nap length of less than 350 μm. The non-woven fabric is used for the preparation of coverings for consumer goods, particularly for the preparation of covers and cases for electronic products.
US09970138B2 Method of converting a glass fibre fabric material and products obtained by the method
In order to recycle glass fiber/fiber fabric production waste material, such as a material used in the manufacturing of rotor blades for wind turbines, and preferably where the material is bendable or flexible and reinforced in a plurality of layers in one or more directions in planes that are parallel with the surface of the material and stitch bonded together, the material is mechanically processed involving a size reduction of the material into shorter fiber length, in order to convert the material into one or more substantial pure glass fiber products. In this way it is possible inter alia to further process the material and create materials such as acoustic insulation wool, and chopped glass fiber strands.
US09970133B2 Woven fabric and garment
Provided are a woven fabric having excellent lightweightness and water resistance and a garment using the woven fabric. The woven fabric has an areal weight of 100 g/m2 or less and a cover factor of 1,800 or more. One of the warp and weft of the woven fabric contains a false-twist crimped yarn, and the other contains a non-crimped yarn.
US09970120B2 Porous, flow-through consumable anodes for use in selective electroplating
A method for electrodepositing a coating/free-standing layer on a workpiece in an electrolytic cell includes moving the workpiece and an anode applicator tool having a consumable anode insert relative to each other; anodically dissolving a metal from the insert and cathodically depositing the metal on the workpiece; providing flow of electrolyte solution through the insert to ensure that greater than 90% of the anodic reaction is represented by dissolution of the metal; recirculating collected electrolyte solution exiting the electrolytic cell through the insert; applying an electric current to the electrolytic cell; maintaining a concentration of the anodically dissolved metal within ±25% of each Ampere-hour per liter of electroplating solution; and creating a cathodic electrodeposit on the workpiece which includes the anodically dissolved metal, the chemical composition of the deposit varying by less than 25% in the deposition direction over a selected thickness of up to 25 microns of the deposit.
US09970115B2 Metal pretreatment composition containing zirconium, copper, zinc, and nitrate and related coatings on metal substrates
A pretreatment composition for metal that provides enhanced corrosion resistance, enhanced paint adhesion and reduced chip damage to a wide variety of metal substrates. The pretreatment is also cleaner because it is based on zirconium rather than zinc phosphates. The pretreatment coating composition in use preferably comprises 50 to 300 parts per million (ppm) zirconium, 0 to 100 ppm of SiO2, 150-2000 ppm of total fluorine and 10-100 ppm of free fluorine, 150 to 10000 ppm of zinc and 10 to 10000 ppm of an oxidizing agent and has a pH of 3.0 to 5.0, preferably about 4.0. The coating composition can optionally include 0 to 50 ppm of copper. The suitable oxidizing agents can be selected from a large group.
US09970103B2 Film deposition material, sealing film using the same and use thereof
The present invention relates to a film composed of a carbon-containing silicon oxide formed by CVD using, as the raw material, an organosilicon compound having a secondary hydrocarbon group directly bonded to at least one silicon atom and having an atomic ratio of 0.5 or less oxygen atom with respect to 1 silicon atom, which is used as a sealing film for a gas barrier equipment and materials, an FPD device, a semiconductor device and the like.
US09970098B2 Movable evaporation source
A moveable evaporation source system may have an insulator disposed above a cathode support member, and a cathode support member disposed beneath the insulator and exerting an upward force on the insulator so that the upward force exerted by the cathode support member urges the insulator toward a down force source. A cathode may be placed between the insulator and the down force source and translated so that material liberated from the cathode may strike different portions of a workpiece as the cathode is translated.
US09970097B2 Rotary evaporation source apparatus for OLED evaporation
The present disclosure discloses a rotary evaporation source apparatus for OLED evaporation, comprising a crucible for containing evaporation material, an evaporation source body for heating the crucible, a rotary disk for rotating the crucible, and a driving source member for driving the rotary disk to rotate; wherein the evaporation source body is provided with a receiving space for receiving the crucible therein, a through hole is disposed on the rotary disk, the rotary disk is movably laid over the evaporation source body, the crucible passes through the through hole disposed on the rotary disk and is placed in the receiving space, the crucible and the rotary disk are disposed in a relatively stationary manner; the driving source member is disposed at outside of the evaporation source body and drives the rotary disk to rotate about a central axis of the evaporation source body, the crucible rotates about the central axis of the evaporation source body along with the rotary disk.
US09970096B2 Intaglio printing plate coating apparatus
There is described an intaglio printing plate coating apparatus comprising a vacuum chamber having an inner space adapted to receive at least one intaglio printing plate to be coated, a vacuum system coupled to the vacuum chamber adapted to create vacuum in the inner space of the vacuum chamber, and a physical vapour deposition (PVD) system adapted to perform deposition of wear-resistant coating material under vacuum onto an engraved surface of the intaglio printing plate, which physical vapour deposition system includes at least one coating material target comprising a source of the wear-resistant coating material to be deposited onto the engraved surface of the intaglio printing plate. The vacuum chamber is arranged so that the intaglio printing plate to be coated sits substantially vertically in the inner space of the vacuum chamber with its engraved surface facing the at least one coating material target. The intaglio printing plate coating apparatus further comprises a movable carrier located within the inner space of the vacuum chamber and adapted to support and cyclically move the intaglio printing plate in front of and past the at least one coating material target.
US09970095B2 Ion assisted deposition top coat of rare-earth oxide
A method of manufacturing an article comprises providing an article. An ion assisted deposition (IAD) process is performed to deposit a second protective layer over a first protective layer. The second protective layer is a plasma resistant rare earth oxide having a thickness of less than 50 microns and a porosity of less than 1%. The second protective layer seals a plurality of cracks and pores of the first protective layer.
US09970091B2 Method for producing two-phase Ni—Cr—Mo alloys
In a method for making a wrought nickel-chromium-molybdenum alloy having homogeneous, two-phase microstructures the alloy in ingot form is subjected to a homogenization treatment at a temperature between 2025° F. and 2100° F., and then hot worked at start temperature between 2025° F. and 2100° F. The alloy preferably contains 18.47 to 20.78 wt. % chromium, 19.24 to 20.87 wt. % molybdenum, 0.08 to 0.62 wt. % aluminum, less than 0.76 wt. % manganese, less than 2.10 wt. % iron, less than 0.56 wt. % copper, less than 0.14 wt. % silicon, up to 0.17 wt. % titanium, less than 0.013 wt. % carbon, and the balance nickel.
US09970089B2 Nickel-chromium-phosphorous brazing alloys
Disclosed is the semi-amorphous, ductile brazing foil with composition consisting essentially of NibalCraBbPcSidMoeFef with approximately 24 atomic percent≤a≤approximately 31 atomic percent; b≤approximately 3 atomic percent; approximately 9 atomic percent≤c≤approximately 11 atomic percent; approximately 2 atomic percent≤d≤approximately 4 atomic percent; e≤approximately 2 atomic percent; f≤approximately 1 atomic percent; and the balance being Ni and other impurities; where b+c+d
US09970086B2 Machine component made of ferrous sintered metal
Raw material powder containing iron powder, copper powder, and tin powder is compressed to form a green compact. The green compact is sintered in a temperature range of from 750 to 900° C., to bond iron structures to each other with copper and tin.
US09970076B2 Method of apparatus for condensing metal vapours using a nozzle and a molten collector
Methods and apparatus for condensing vapour phase compounds or elements, typically metals such as magnesium, obtained by reduction processes.
US09970075B2 Sulfonamide-based separation media for rare earth element separations
A sulfonamide based rare earth element ion separation media and method of synthesis and use are provided. A bed or column of sulfonamide resin for separations can be prepared by exposing a sulfonate resin to chlorosulfonic acid to form a sulfonyl chloride resin; exposing the sulfonyl chloride resin to aqueous ammonia to form a sulfonamide resin; and then packing the sulfonamide resin into a separation column. Mixtures of lanthanide and other rare earth ions with very similar atomic radii and characteristics can be separated by flowing a mixture of lanthanide ions through a bed of sulfonamide resin followed by a mobile phase of an organic acid such as lactic acid to elute the separated rare earth element ions separated by the sulfonamide resin. Collected fractions of eluate can also be recycled through the sulfonamide media.
US09970071B2 Method for reducing iron oxide to metallic iron using coke oven gas
The present invention provides a method for reducing iron oxide to metallic iron using coke oven gas, including: dividing coke oven gas from a coke oven gas source into a plurality of coke oven gas streams; providing a first coke oven gas stream to a hydrogen enrichment unit to form a hydrogen-rich product stream that is delivered to a reduction shaft furnace as part of a reducing gas stream; and providing a tail gas stream from the hydrogen enrichment unit to a reforming reactor to form a reformed gas stream that is delivered to a reduction shaft furnace as part of the reducing gas stream. Optionally, a spent top gas stream from the reduction shaft furnace is cleansed of CO2 and recycled back to the reducing gas stream.
US09970066B2 Method of detecting Coccidioides species
The present technology provides methods and kits that may be used to detect and quantify the presence of Coccidioides species. The methods include quantification real-time PCR assays, and the kits and compositions include oligonucleotides used as primers and probes.
US09970060B2 Quantitation and profiling of vaginal microflora
Disclosed are methods of quantifying microflora in vaginal samples. Quantitative assessment of vaginal microflora by real-time PCR to create a profiling of Lactobacillus species, Gardnerella vaginalis, Atopobium vaginae, Megasphaera Type 1 and Type 2 and BVAB2 permits evaluation of bacterial vaginosis. Kits containing reagents for quantitative assessment of microflora are also disclosed.
US09970058B2 Digital amplification
The identification of pre-defined mutations expected to be present in a minor fraction of a cell population is important for a variety of basic research and clinical applications. The exponential, analog nature of the polymerase chain reaction is transformed into a linear, digital signal suitable for this purpose. Single molecules can be isolated by dilution and individually amplified; each product is then separately analyzed for the presence of pre-defined mutations. The process provides a reliable and quantitative measure of the proportion of variant sequences within a DNA sample.
US09970056B2 Methods and kits for diagnosing, prognosing and monitoring parkinson's disease
Network-based meta-analysis of four independent microarray studies identified the hepatocyte nuclear factor (HNF4A), a transcription factor associated with gluconeogenesis and diabetes, as a central regulatory hub gene upregulated in blood of PD patients. In parallel, the polypyrimidine tract binding protein 1 (PTBP1), involved in the stabilization and mRNA translation of insulin, was identified as the most downregulated gene. Using both markers, PD patients were classified with 90% sensitivity and 80% specificity. Longitudinal performance analysis demonstrated that relative abundance of HNF4A and PTBP1 mRNAs significantly decreased and increased, respectively, in PD patients during 3 years follow up period. The inverse regulation of HNF4A and PTBP1 provides a molecular rationale for the altered insulin signaling observed in PD patients. The longitudinally dynamic biomarkers identified in this study may be useful for monitoring disease-modifying therapies for PD.
US09970053B2 Washing-free template-ready PCR detection method for RNA
Provided in the present invention is a washing-free template-ready PCR detection method for RNA. On the basis of retaining the advantages of the original template-ready PCR method, i.e., there being no need to purify and extract the RNA, no need for a reverse transcription reaction, etc., the method of the present invention designs a probe for the restriction enzymes to thereby integrate the enzyme digestion reaction, so as to eliminate the interference of various pollution sources of double-stranded DNA with no need for a washing step.
US09970047B2 Quantitative assessment for cap efficiency of messenger RNA
The present invention provides, among other things, methods of quantitating mRNA capping efficiency, particularly for mRNA synthesized in vitro. In some embodiments, the methods comprise chromatographic methods of quantifying capping efficiency and methylation status of the caps.
US09970045B2 Cellular analysis of body fluids
Herein is provided a simple, reliable and accurate method for cellular analysis on hematology analyzers. In various aspects, the methods provide separation and/or differentiation between red blood cells (RBCs) and white blood cells (WBCs) by utilizing a fluorescent dye to selectively stain WBCs such that they emit stronger fluorescence signals. The method provides optimal detection limits on WBCs and RBCs, thereby allowing analysis of samples with sparse cellular concentrations. As few as one reagent may be used to prepare a single dilution for body fluid analysis, in order to simplify the body fluid analysis. Minimal damage to WBCs is attained using the lysis-free approach described in aspects of the disclosure.
US09970040B2 Engineering DNA assembly in vivo and methods of making and using the reverse transcriptase technology
Cells that can synthesize oligonucleotides in vivo to produce a nucleic acid nanostructure are described. Methods for producing oligonucleotide nanostructures for use in regulating gene expression and altering biological pathways are provided. Methods of performing multiplex automated genome editing (MAGE) are also provided.
US09970037B2 Methods and materials for making simvastatin and related compounds
The invention disclosed herein relates to methods and materials for producing simvastatin and related compounds such as huvastatin.
US09970031B2 Method for producing dicarboxylic acid
A method for producing a dicarboxylic acid is provided. A dicarboxylic acid is produced by culturing a bacterium having a dicarboxylic acid-producing ability, which has been modified so that the expression of one or more of the yeeA gene, ynfM gene, yjjP gene, and yjjB gene is increased, in a medium, and collecting the dicarboxylic acid from the medium.
US09970019B2 Regulatory nucleic acid molecules for enhancing seed-specific and/or seed-preferential gene expression in plants
The present invention is in the field of plant molecular biology and provides methods for production of high expressing seed-specific and/or seed-preferential promoters and the production of plants with enhanced seed-specific and/or seed-preferential expression of nucleic acids wherein nucleic acid expression enhancing nucleic acids (NEENAs) are functionally linked to the promoters and/or introduced into plants.
US09970014B2 Factor V/Va-targeting aptamer compositions and methods of using the same
Provided herein are Factor V/Factor Va-targeting aptamer compositions and antidote compositions targeting such aptamer compositions. Methods for preventing blood clots using such compositions are also provided.
US09970009B2 MicroRNA compounds and methods for modulating miR-21 activity
Described herein are compositions and methods for the inhibition of miR-21 activity. The compositions have certain nucleoside modification patterns that yield potent inhibitors of miR-21 activity. The compositions may be used to inhibit miR-21, and also to treat diseases associated with abnormal expression of miR-21, such as fibrosis and cancer.
US09970003B2 Method of treating pain with an antibody against netrin-4, Unc5B or neogenin
The present invention provides a screening method for pain suppressors, which method is characterized by using netrin-4 and/or a netrin-4 receptor to select a substance capable of inhibiting downstream signaling from netrin-4. According to the screening method of the present invention, pain suppressors useful as a preventive or therapeutic medicine for pain can be identified. The present invention also provides a pharmaceutical composition for prevention or treatment of pain, which composition comprises, as an active ingredient, a substance capable of inhibiting downstream signaling from netrin-4.
US09970002B2 Compositions and methods for functional nucleic acid delivery
Provided are derivatized therapeutic, prophylactic, or diagnostic agents, such as nucleic acids, that can be effectively delivered to cells and tissues. Also provided are methods of affecting a biological process by administering a therapeutic, prophylactic, or diagnostic agent, such as functional nucleic acid, to a cell or a subject, where the therapeutic, prophylactic, or diagnostic agent, such as functional nucleic acid, is derivatized therapeutic, prophylactic, or diagnostic agent, such as nucleic acid.
US09970001B2 Methods and compositions for nuclease design
Methods and compositions for genetic alteration of cells are provided.
US09970000B2 Cell-based composite materials with programmed structures and functions
The present invention is directed to the use of silicic acid to transform biological materials, including cellular architecture into inorganic materials to provide biocomposites (nanomaterials) with stabilized structure and function. In the present invention, there has been discovered a means to stabilize the structure and function of biological materials, including cells, biomolecules, peptides, proteins (especially including enzymes), lipids, lipid vesicles, polysaccharides, cytoskeletal filaments, tissue and organs with silicic acid such that these materials may be used as biocomposites. In many instances, these materials retain their original biological activity and may be used in harsh conditions which would otherwise destroy the integrity of the biological material. In certain instances, these biomaterials may be storage stable for long periods of time and reconstituted after storage to return the biological material back to its original form. In addition, by exposing an entire cell to form CSCs, the CSCs may function to provide a unique system to study enzymes or a cascade of enzymes which are otherwise unavailable.
US09969999B2 Method for producing alpha-santalene
The present invention provides a method of producing α-santalene by contacting at least one polypeptide with farnesyl phyrophosphate (fpp). In particular, the method may be carried out in vitro or in vivo to produce α-santalene, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of a polypeptide useful in the method of the invention. A nucleic acid encoding the polypeptide of the invention and an expression vector containing the nucleic acid represent part of the present invention. A non-human host organism and a cell transformed to be used in the method of producing α santalene are also part of the present invention.
US09969988B2 Pipecolinic acid 4-hydroxylase and method for producing 4-hydroxy amino acid using same
The present invention provides a pipecolic acid 4-hydroxylase protein exemplified by the following (A), (B), and (C), having activity to react with L-pipecolic acid in the presence of 2-oxoglutaric acid and iron(II) ions to produce trans-4-hydroxy-L-pipecolic acid, and a method for producing 4-hydroxy amino acid, which method comprises reacting the pipecolic acid 4-hydroxylase protein, cells containing the protein, a treated product of the cells, and/or a culture liquid obtained by culturing the cells, with α-amino acid to produce 4-hydroxy amino acid: (A) a polypeptide comprising the amino acid sequence represented by SEQ ID NO:2, 4, 6, 8, 10, 12, 16, or 18; (B) a polypeptide comprising the amino acid sequence represented by SEQ ID NO:2, 4, 6, 8, 10, 12, 16, or 18 except that one or several amino acids are deleted, substituted, and/or added, and having pipecolic acid 4-hydroxylase activity; and (C) a polypeptide having an amino acid sequence that is not less than 80% identical to the amino acid sequence represented by SEQ ID NO:2, 4, 6, 8, 10, 12, 16, or 18, and having pipecolic acid 4-hydroxylase activity.
US09969982B2 Differentiation of human embryonic stem cells
The present invention provides methods to promote the differentiation of pluripotent stem cells and the products related to or resulting from such methods. In particular, the present invention provides an improved method for the formation of pancreatic hormone expressing cells and pancreatic hormone secreting cells. In addition, the present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer and the products related to or resulting from such methods. The present invention also provides methods to promote glucose-stimulated insulin secretion in insulin-producing cells derived from pluripotent stem cells.
US09969978B2 Method for producing cardiomyocytes from human or mouse embryonic stem cells in a medium consisting of a serum-free medium and N2 supplement
The present invention relates to a method for producing embryonic stem cell-derived cardiomyocytes, cardiomyocytes produced by the method, a method for producing cardiomyocyte bodies from the cardiomyocytes, cardiomyocyte bodies produced by the method, a cellular therapeutic agent comprising the cardiomyocyte bodies as an active ingredient for the treatment of cardiac diseases, a method for treating cardiac diseases using the cellular therapeutic agent, and use of cardiomyocytes or cardiomyocyte bodies for the preparation of the cellular therapeutic agent. The method for producing cardiomyocytes of the present invention can be used to easily purify differentiated cardiomyocytes from embryonic stem cells. Further, the purified cardiomyocytes can be used to produce cardiomyocyte bodies, which can be used as a cellular therapeutic agent for treating cardiac diseases. Therefore, the cardiomyocyte bodies can be widely applied to the development of prophylactic or therapeutic agents for cardiac diseases.
US09969976B2 Cell populations having immunoregulatory activity, methods for the preparation and uses thereof
A method for the preparation and/or generation of immunomodulatory cells which comprises contacting a mesenchymal stem cell (MSC) and/or fibroblast cell population with peripheral blood leukocytes for between about 2 hours and about 25 days is described herein.
US09969975B1 Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene
Disclosed herein is a genetically-modified cell comprising in its genome a modified human T cell receptor alpha constant region gene, wherein the cell has reduced cell-surface expression of the endogenous T cell receptor. The present disclosure further relates to methods for producing such a genetically-modified cell, and to methods of using such a cell for treating a disease in a subject.
US09969971B2 Calcium-containing structures and methods of making and using the same
The present invention generally relates to calcium-containing structures and methods of making and using the structures. In one aspect, hollow calcium containing microstructures are used in conjunction with bone tissues/by-products to augment bone defects and extend the supply of bone tissues/by-products for bone augmentation. Bonding agents, such as calcium cements, are also used in the preparation of the hollow calcium microstructures combined with bone tissues/by-products or for use in preparing the hollow microstructures. The calcium-containing microstructures of the present invention are also useful as delivery vehicles of nitric oxide and/or nitric oxide containing or producing compounds for a variety of in vitro and in vivo uses. Calcium containing contoured substrates upon which cells/tissues can be grown in vitro for replacement and repair of tissues in vivo that conform in size and shape to the tissue surface to be replaced are also provided.
US09969968B2 Hydrodynamic separation (HDS) for removing protist predators from algal crops
A method and system removes biological contaminants from an algal crop. A flow of an algal crop containing biological contaminants is provided to a hydrodynamic separator (HDS) system. The flow is controlled by a control mechanism, wherein the biological contaminants are concentrated into a first portion of the flow of the algal crop within the HDS system, based on the size of the biological contaminants, and the first portion contains a majority of the biological contaminants in the flow of the algal crop. A second portion of the flow contains a majority of algal in the flow of the algal crop. The flow of the algal crop is split by use of a bi-furcated output of the HDS system. The splitting is between the first portion containing the majority of the biological contaminants in the flow of the algal crop, and the second portion which contains the majority of the algal of the algal crop. The first portion of the flow of the algal crop containing the majority of the biological contaminants is output from a first output of the bi-furcated output, and the second portion of the flow of the algal crop containing the majority of the algal of the algal crop is output from a second output of the bi-furcated output.
US09969964B2 Disease-on-a-chip
The invention generally relates to a cell culture system for coculturing non-neoplastic and neoplastic cells on a planar member which more faithfully mimics the in vivo geometry of a lumen or a cavity.
US09969963B2 Methods and apparatus for cell culture array
Methods and systems are described for improved handling and/or culturing and/or assaying of cells, chemically active beads, or similar materials in microfluidic systems and microfluidic culture arrays.
US09969943B2 Use of magnetic nanoparticles for depletion of aromatic compounds in oil
A method of treating crude oil comprising depleting the content of aromatic hydrocarbons comprising contacting the crude oil with super-paramagnetic or paramagnetic nanoparticles comprising chemical functional groups. The method increases the API gravity of crude oil and reduces the viscosity of said oil. Oil can be depleted in its content of sulphur-containing aromatics using functionalized nanoparticles.
US09969940B2 Use of renewable oil in hydrotreatment process
The use of bio oil from at least one renewable source in a hydrotreatment process, in which process hydrocarbons are formed from said glyceride oil in a catalytic reaction, and the iron content of said bio oil is less than 1 w-ppm calculated as elemental iron. A bio oil intermediate including bio oil from at least one renewable source and the iron content of said bio oil is less than 1 w-ppm calculated as elemental iron.
US09969924B2 Dual function internal breaker for crosslinked hydroxyethylcellulose
Treatment fluids for use in a well, the treatment fluids including: (a) water; (b) hydroxyalkylcellulose, wherein the hydroxyalkylcellulose is hydrated in the water-based continuous phase; (c) a crosslinker for the hydroxyalkylcellulose; (d) magnesium peroxide in particulate form; and (e) a transition metal containing complex having at least one organic ligand. Methods of treating a treatment zone in a well, the methods comprising: (A) forming a treatment fluid according to the disclosure; and (B) introducing the treatment fluid into a well.
US09969923B2 Sealant compositions for use in subterranean formation operations
Embodiments herein include methods comprising providing a sealant composition comprising an aqueous base fluid, a crosslinkable polymer composition, and a density segregation prevention agent, wherein the crosslinkable polymer composition comprises a crosslinkable organic polymer and a crosslinker; introducing a particulate density reducing agent into the sealant composition, wherein the particulate density reducing agent causes the sealant composition to adopt a reduced density as compared to the sealant composition without the particulate density reducing agent, thereby creating a reduced density sealant composition; introducing the reduced density sealant composition into a subterranean formation; and crosslinking the reduced density sealant composition into a gel to form a seal in the subterranean formation.
US09969919B2 Silicone composition and method for manufacturing heat-conductive silicone composition
A silicone composition that contains an organopolysiloxane having at least two aliphatic unsaturated hydrocarbon groups per molecule, a filler containing an aluminum powder and a zinc oxide powder, an organohydrogenpolysiloxane having two or more SiH groups per molecule, and a platinum group metal catalyst, in which when a storage and loss elastic modulus G″ of the silicone composition is measured by means a viscoelasticity measurement apparatus capable of measuring shear modulus, the silicone composition can provide a cured product wherein G′ after 3,000 seconds from the start of holding is 10,000 Pa or less, G′ after 7,200 seconds from the start of holding is 100,000 Pa or less, and G′ exceeds G″ after 800 seconds or more from the start of holding. As a result, there is provided a silicone composition excellent in crushability, spreadability, and heat conductivity, and further provided a method for manufacturing a heat-conductive silicone composition.
US09969908B2 Method for removing permeates from flat structures, and corresponding adhesive tape
The invention relates to an easy-to-carry-out and effective method and a suitable device for absorbing permeates from flat structures. The method according to the invention comprises the following steps: gluing an adhesive tape containing at least one getter material onto the flat structure, storing the composite so obtained and consisting of the adhesive tape and the flat structure, and removing at least part of the adhesive tape which contains a getter material from the flat structure, the adhesive tape being designed to absorb at least partially at least one permeate from the flat structure. The invention further relates to an adhesive tape comprising at least one substrate layer having a water vapor permeation rate of <1 g/(m2*d) (measured according to ASTM F-1249 at 38° C. and 90% relative humidity), to an adhesive compound and to at least one getter material arranged between the substrate layer and the adhesive compound or contained in the adhesive compound and capable of absorbing at least one substance capable of permeation, characterized in that the adhesive compound is reversible. In a preferred embodiment, the getter material is selected from the group comprising calcium oxide, calcium sulfate, calcium chloride, pyrogenic silica and zeolites and mixture of two or more of the above substances.
US09969906B2 Radical curable adhesive composition, and polarizing plate and optical member comprising same
The present invention relates to a radical-curable adhesive composition including an acid anhydride-based compound having at least one carbon-carbon unsaturated double bond, a vinyl-based compound having at least one electron donor group, a radical initiator, and a cation generator, wherein the content of the acid anhydride-based compound and the vinyl-based compound is 0.8 to 1.0 by an equivalence ratio of mixing represented by the following Equation (1), and a polarizing plate and an optical member including the radical-curable adhesive composition: Equivalence Ratio of Mixing=M/N,  Equation(1): and in Equation (1), M is the number of carbon-carbon unsaturated double bonds capable of participating in polymerization in the molecule including an acid anhydride group included in the acid anhydride-based compound; and N is the number of carbon-carbon unsaturated double bonds capable of participating in polymerization in the molecule included in the vinyl-based compound.
US09969904B2 Epoxy-fortified floor polishes
An aqueous composition comprising: (a) an aromatic-acrylic polymer comprising from 3 to 11 wt % polymerized units of C3-C6 carboxylic acid monomers and from 0.2 to 3 wt % polymerized units of anti-agglomerating monomers; (b) a reactive polyfunctional thermosetting resin; (c) a polyvalent metal ion; and (d) a polyfunctional curing agent, wherein the curing agent is stored separately from the thermosetting resin.
US09969903B2 Method of applying an organosilane solution to rigid substrates and grout
A stain-treated substrate comprising an extremely thin coating for stain protection. The stain-treated substrate includes substrate material and the extremely thin coating include a molecular layer of organosilane 3-(trimethoxysilyl) propyldimethyl octadecyl ammonium chloride covalently bonded to the surface of the substrate material. The substrate material can include a wide variety of materials including tile, ceramic, glass, stone and marble and can optionally be used in conjunction with a grout mixture including a diluted organosilane mixture.
US09969889B2 Corrosion-resistant structure for high-temperature water system and corrosion-preventing method thereof
The present invention provides a corrosion-resistant structure for a high-temperature water system comprising: a structural material 1; and a corrosion-resistant film 3 formed from a substance containing at least one of La and Y deposited on a surface in a side that comes in contact with a cooling water 4, of the structural material 1 which constitutes the high-temperature water system that passes a cooling water 4 of high temperature therein. Due to above construction, there can be provided the corrosion-resistant structure and a corrosion-preventing method capable of operating a plant without conducting a water chemistry control of cooling water by injecting chemicals.
US09969888B2 Process for manufacturing aqueous suspensions of mineral materials or dried mineral materials, the obtained products, as well as uses thereof
The invention relates to a process for manufacturing aqueous mineral material suspensions or dried mineral materials using at least one lithium ion neutralized water-soluble organic polymer, the ground mineral materials obtained by this process, the use of the mineral materials in paper, paints and plastics, as well as the use of the lithium ion neutralized water-soluble organic polymer in the manufacturing process as a dispersing and/or grinding enhancer.
US09969885B2 Anti-adherent composition
Compositions for inhibiting the attachment of microbes to a biotic or abiotic surface are disclosed. The compositions include a carrier and an effective amount of an anti-adherent agent. The anti-adherent agents include Cyclopentasiloxane (and) Dimethiconol, sodium polystyrene sulfonate, Acrylates/Vinyl Neodecanoate Crosspolymer, Ammonium Acryloyldimethyltaurate/VP Copolymer, Polyquaternium-22, Hydroxypropyl methylcellulose, Polyquaternium-7, Acrylates/Aminoacrylates/C10-30 Alkyl PEG-20 Itaconate Copolymer and combinations thereof. Various delivery vehicles, such as wipes, may be used to deliver the composition to surfaces.
US09969877B2 Resin compositions, resin molded articles, processes for preparing resin molded articles, and laser direct structuring additives
Provided is a resin composition having higher platability. The resin composition contains at least two kinds of metals and also containing a conductive oxide having a resistivity of 5×103 Ω·cm or less.
US09969875B2 Polyacetal resin composition and sliding member
A polyacetal resin composition which not only is highly inhibited from making creaking sounds but also has satisfactory performances with respect to other properties. The polyacetal resin composition includes 100 parts by weight of a polyacetal resin, 0.01-1 part by weight of a hindered phenolic antioxidant, 0.01-1 part by weight of a nitrogenous compound, 0.1-1 part by weight of a graft copolymer, 0.1-1 part by weight of a fatty acid ester, 0.5-5 parts by weight of a silicone oil, and 0.1-1 part by weight of calcium carbonate. The nitrogenous compound may be an aminotriazine compound, the graft copolymer includes an olefin-based polymer as the main chain and a vinyl-based polymer as side chains, the fatty acid ester includes a C12-32 fatty acid and a C2-30 mono- or polyhydric alcohol, and the calcium carbonate has an average particle diameter of 1 μm or smaller.
US09969871B2 Heterophasic polymer composition for cable insulation layer, cable insulation layer and power cable including the same
Disclosed is a heterophasic polymer composition for environmentally friendly cable insulation layers that exhibits excellent electrical, mechanical, and thermal properties while realizing the flexibility, bendability, and impact resistance performance characteristics of polypropylene. The heterophasic polymer composition for cable insulation layers is configured such that propylene copolymer particles each having a predetermined size are dispersed in a polypropylene matrix.
US09969862B2 Plasticizers for polymers
The present invention refers to plasticizers derived from vegetable oils for thermoplastic polymers and resins, in particular, plasticizers for Polyvinylchloride (PVC). Furthermore, the invention relates to a method for preparing such plasticizers. Plasticizers comprise esters of carboxyl fatty acids wherein fatty acids are selected from those having a hydrocarbon chain comprised between C12 e C22, wherein the double bonds of the hydrocarbon chain of the carboxylic fatty acid are epoxidized, and the esterification is with a cyclic acetal or ketal.
US09969857B2 Single-screw extrusion desulfurization and post-processing system, and method for preparing reclaimed rubber
A single-screw extrusion desulfurization and post-processing system and a method for preparing reclaimed rubber. The single-screw extrusion desulfurization and post-processing system comprises: a single-screw desulfurization device, a single-screw post-processing device and a closed connection device for connecting the single-screw desulfurization device and the single-screw post-processing device, the single-screw post-processing device includes a post-processing feeding unit and a post-processing unit which are connected with each other, and a post-processing screw running through the post-processing feeding unit and the post-processing unit.
US09969852B2 Epoxy resin formulations
Epoxy formulations comprising a polyfunctional epoxy resin, a solid bisphenol A epoxy resin, a phenolic end capped bisphenol A resin, a rubber epoxy adduct and a curative are provided as is their use in prepregs and as matrix materials in laminates of metal foil and fiber reinforced epoxy resins.
US09969850B2 Method for producing modified polymer, and rubber composition
Acido-basic properties of a system containing a polymer obtained by decomposing by oxidative cleavage of a carbon-carbon double bond, and a trifunctional molecule having an alkoxysilyl group in the structure as represented by the formula (A) are changed such that the system is changed into a basic system when the system is acidic and the system is changed into an acidic system when the system is basic to combine the decomposed polymer and the trifunctional molecule, thereby introducing the alkoxysilyl group into the main chain. Furthermore, acido-basic properties of a system containing a polymer obtained by decomposing by oxidative cleavage of a carbon-carbon double bond to decrease the molecular weight, and a functional molecule having an alkoxysilyl group as represented by the formula (a) are changed in the same manner as above to combine the decomposed polymer and the functional molecule, thereby introducing the alkoxysilyl group in a molecular terminal.
US09969848B2 Fluoropolymer compositions containing a polyhydroxy surfactant
Provided are aqueous fluoropolymer dispersions containing at least one tetrafluoroethene homopolymer or tetrafluoroethene copolymer and at least one non-aromatic polyhydroxy surfactant. The dispersions contain from 0 to 100 ppm based on the total weight of the dispersion of fluorinated surfactants. Also provided are methods of coating using the dispersions and substrate coated with the dispersions.
US09969846B1 Gluten-derived flame retardant macromolecules
A gluten-derived flame retardant macromolecule includes a phosphorus moiety chemically bonded to an amino acid side chain of a gluten protein.
US09969844B2 Silicone ligands for quantum dots
The present invention relates to silicone polymer ligands for binding to quantum dots. The silicone polymer ligands contain a multiplicity of amine, carboxy, and/or phosphine binding groups suitable for attachment to quantum dots. The present invention also describes a process for the preparation of quantum dot binding ligands.
US09969843B2 Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same
A polymer (A) having, at one terminal moiety thereof, a terminal structure having two or more carbon-carbon unsaturated bonds. A reactive-silicon-group-containing polymer (B) having, at one terminal moiety thereof, a terminal structure having two or more reactive silicon groups.
US09969842B2 Method of preparing poly(alkylene carbonate) via copolymerization of carbon dioxide/epoxide in the presence of novel complex
Provided is a method of preparing poly(alkylene carbonate) using a molecular weight regulator in a process of preparing a copolymer of carbon dioxide/epoxide using a novel complex synthesized from salen-type ligand including a quaternary ammonium salt as a catalyst. According to the present invention, even though the molecular weight regulator is used, an activity of the catalyst may be stably maintained, whereby the low molecular weight of poly(alkylene carbonate) having a desirable level may be effectively provided. In addition, it is expected that since the novel complex as the catalyst of the present invention has a simple structure as compared to the existing copolymerization catalyst, due to the economical preparation cost thereof, the novel complex may be effectively applied to a large-scale commercial process.
US09969841B2 Copolycarbonate and composition comprising the same
The present invention relates to a copolycarbonate and a molded article comprising the same. The copolycarbonates according to the present invention has a structure in which a specific siloxane compound is introduced in a main chain of the polycarbonate, and has effects of improving impact strength at room temperature, impact strength at low temperature, and melt index properties.
US09969831B2 Functionalized elastomer
The present invention is directed to a copolymer of 1,3-butadiene or isoprene and a monomer of formula I or formula II where R1 is a covalent bond or C1 to C8 linear or branched alkanediyl; R2, R3, R4 are independently C1 to C8 linear or branched alkyl or —OR6, where R6 is C1 to C8 linear or branched alkyl, with the proviso that at least one of R2, R3, and R4 is —OR6, and where R5 is hydrogen or C1 to C8 linear or branched alkyl. The invention is further directed to a rubber composition including the copolymer, and a pneumatic tire containing the rubber composition. The invention is further directed to a method of making such a copolymer.
US09969830B2 Oxazoline modified copolymer, composition including oxazoline modified copolymer, and article manufactured from the composition
A copolymer includes a first structural unit selected from Chemical Formula 1, Chemical Formula 2, and a combination thereof and a second structural unit selected from Chemical Formula 3, Chemical Formula 4, and a combination thereof; and a composition including the copolymer and an article manufactured from the composition are provided. Definitions of Chemical Formulae 1 to 4 are the same as described in the detailed description.
US09969829B2 Polymer compound, negative resist composition, laminate, patterning process, and compound
The present invention provides a polymer compound containing a repeating unit shown by the following general formula (1). There can be provided a polymer compound usable in a negative resist composition that can achieve high resolution of 50 nm or less and small LER and cause very few defects, a negative resist composition using the polymer compound, and a patterning process using the negative resist composition.
US09969824B2 Transparent peroxide curable butyl rubber
The present invention provides an optically transparent peroxide cured article made from a peroxide curable butyl rubber ionomer comprising repeating units derived from the reaction product of one or more multiolefin monomers and at least one nitrogen or phosphorous based nucleophile comprising a pendant vinyl group. A process is also disclosed for making the optically transparent article.
US09969818B2 Integrated process for processing and utilising the guayule plant
The present invention relates to an integrated process for processing and utilizing every part of the guayule plant (Parthenium argnetatum) which comprises the following steps in sequence: separating the stem and branches from the leaves of said plant with a mechanical treatment; treating the leaves to produce waxes and essential oils, and a fraction containing cellulose, hemicellulose (carbohydrates) and, to a minor extent, salts, organic compounds and lignin; extracting from the stem and branches a liquid phase, so forming a first solid woody residue, indicated with bagasse in the present text; treating said first solid woody residue to prepare sugars, resin, rubber and lignin.
US09969813B2 Multi-specific monoclonal antibodies
The present invention is relevant to the generation of multi-specific antibodies, antibodies that are distinguished by their ability to bind to multiple antigens with specificity and with affinity. In particular, the present invention is related to bi-specific antibodies.
US09969812B2 Anti human Notch4 antibody
The present invention provides an anti-human Notch4 antibody or a Notch4 binding fragment thereof that may have neutralizing activity against human Notch4, as well as a pharmaceutical composition comprising the same as the active ingredient. The present inventors obtained a mouse anti-human Notch4 antibody that has high neutralizing activity and binding affinity towards human Notch4 and determined the complementarity determining region (CDR) sequence of the mouse anti-human Notch4 antibody. This enabled the production of a humanized antibody comprising the variable region of heavy and light chains as well as the CDR sequence of the mouse anti-human Notch4 antibody.
US09969807B2 Antibody therapeutics that bind CD123
There is disclosed compositions and methods relating to or derived from anti-CD123 antibodies. More specifically, there is disclosed fully human antibodies that bind CD123, CD123-antibody binding fragments and derivatives of such antibodies, and CD123-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating a disease.
US09969796B2 Peptides and binding partners therefor
The invention provides a peptide obtainable from C. albicans as well as variants and fragments thereof, and labelled forms of these. The peptide is immunogenic and specific binding partners for the peptide and labelled forms of these specific binding partners form a further aspect of the invention. The peptide is a fragment of the ECE1 protein and has been found to be both immunogenic and act as a pore-forming toxin. A range of therapeutic and diagnostic applications for the peptide and the specific binding partners for it form further aspects of the invention. In addition, the peptide may be used in screens for identifying compounds having useful anti-fungal activity.
US09969790B2 Compositions and methods for immunomodulation in an organism
The present invention relates to a therapeutic polypeptide and methods for its creation and use for modulating an immune response in a host organism in need thereof. In particular, the invention relates to the administration to an organism in need thereof, of an effective amount of a pre-coupled polypeptide complex comprising a lymphokine polypeptide portion, for example IL-15 (SEQ ID NO: 5, 6), IL-2 (SEQ ID NO: 10, 12) or combinations of both, and an interleukin receptor polypeptide portion, for example IL-15Ra (SEQ ID NO: 7, 8), IL-2Ra (SEQ ID NO: 9, 11) or combinations of both, for augmenting the immune system in, for example, cancer, SCID, AIDS, or vaccination; or inhibiting the immune system in, for example, rheumatoid arthritis, or Lupus. The therapeutic complex of the invention surprisingly demonstrates increased half-life, and efficacy in vivo.
US09969787B2 Glucagon-like-peptide-2 (GLP-2) analogues
GLP-2 analogs are disclosed which comprise one of more substitutions as compared to h[Gly2]GLP-2 and which may have the property of an altered GLP-1 activity, and their medical use. The analogs are particularly useful for the prophylaxis treatment or ameliorating of the gastro-intestinal associated side effects of diabetes.
US09969784B2 Compositions and methods for modulation of immune function
Compositions and methods for modulating immune cell function and Nedd-4 family member signaling are disclosed.
US09969773B2 Polymers, pharmaceutical compositions and methods of synthesizing the same
Novel methods to prepare novel polymers are disclosed. Oxazolidinyl compounds according to formula IV: are also disclosed as intermediate compounds that can be reacted with an acid to form a polymer of formula I.
US09969768B1 Oleanolic acid methyl ester derivatives
Oleanolic acid methyl ester derivatives demonstrate potent anti-diabetic activities. In in vitro anti-diabetic testing, the derivatives showed more potency regarding dipeptidyl peptidase-4 (DPP-IV) inhibitor activity, peroxisome proliferator-activated receptors (PPARs) agonist activity, and α-Glucosidase inhibitors activity, as compared to reference standards oleanolic acid and acarbose. In in vivo oral hypoglycemic testing, both acute and sub-acute studies demonstrated that the derivatives had high potency and long duration of action compared to the reference standards pioglitazone, acarbose and oleanolic acid.
US09969767B2 Oxolupene derivatives
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I and II: These compounds are useful for the treatment of HIV and AIDS.
US09969765B2 Nuclions and ribocapsids
The invention relates to an isolated nuclion having (i) a core nucleic acid, and (ii) one or more ribocapsids each including a polymer of two or more ribocapsid subunits, wherein said ribocapsid subunits include nucleic acid. The invention also relates to a method for manufacturing an isolated nuclion.
US09969763B2 1,2,3-triazole-tethered carbohydrate-di and tri lipidated cysteine conjugates useful as vaccine adjuvants and process for preparation thereof
The present invention relates to carbohydrate-di and tri lipidated cysteine based 1,2,3-triazoles useful as vaccine adjuvants of formula 1 The present invention also provides process for preparation of carbohydrate-di and tri lipidated cysteine based 1,2,3-triazoles. The carbohydrate-di and tri lipidated cysteine based 1,2,3-triazoles as vaccine adjuvants are useful in formulations for therapeutic and prophylactic vaccines against bacterial, viral, protozoan infections and cancer.
US09969758B2 Antimicrobial compounds
An antimicrobial compound, as well as the salts, derivatives and analogs thereof, said compound being represented by the general formula (I): wherein R1 represents a peptide part P1 or a peptide part P2.
US09969755B2 Photodynamic therapy photosensitizers
A compound of formula (I) useful as a photosensitizer in photodynamic therapy is provided. There is also provided a photosensitizing composition for use in photodynamic therapy comprising this compound. Finally, there are provided a method of killing cells under oxidative stress conditions and a method for the selective delivery of singlet oxygen (1O2) to cells having an increased reactive oxygen species (ROS) concentration, these methods comprising the steps of contacting such cells with a compound of formula (I), and exposing the cells to light.
US09969751B2 High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds
The invention provides compositions of novel high penetration compositions (HPC) or high penetration prodrugs (HPP) of antimicrobials and antimicrobial-related compounds, which are capable of crossing biological barriers with high penetration efficiency. The HPCs/HPPs are capable of being converted to parent active drugs or drug metabolites after crossing the biological barrier and thus can render treatments for the conditions that the parent drugs or metabolites can. Additionally, the HPPs are capable of reaching areas that parent drugs may not be able to access or to render a sufficient concentration at the target areas and therefore render novel treatments. The HPCs/HPPs can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject and enter the general circulation with a faster rate.
US09969748B2 Fused bicyclic heteroaromatic derivatives as kinase inhibitors
A series of fused bicyclic heteroaromatic derivatives of formula (IA) or (IB), as defined herein, being selective inhibitors of phosphatidylinositol-4-kinase IIIβ (PI4KIIIβ) activity, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases and malaria; and organ and cell transplant rejection.
US09969742B2 Imidazotriazinone compounds
The present invention provides imidazotriazinone compounds which are inhibitors of phosphodiesterase 9 and pharmaceutically acceptable salt thereof. The present invention further provides processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of PDE9 associated diseases or disorders in mammals, including humans.
US09969740B2 Forms of a PI3K delta selective inhibitor for use in pharmaceutical formulations
The present invention relates to solid state forms of a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta inhibitor (S)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one (TGR-1202). The present invention also relates to methods of preparing the same, pharmaceutical compositions containing them, and methods of treating a PI3K kinase mediated disease or disorder, such as cancer, by administering the same.
US09969738B2 N-acyl-(3-substituted)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor-mediated disorders
Novel compounds of Formula I and their use in therapeutic treatments.
US09969727B2 Pyrrolopyridines as kinase inhibitors
Compounds of Formula I are useful for inhibition of CHK1 and/or CHK2. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
US09969724B2 Factor IXa inhibitors
In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
US09969723B2 3-(4-(benzyloxy)phenyl)hex-4-ynoic acid derivative, method of preparing same and pharmaceutical composition for preventing and treating metabolic disease including same as effective ingredient
The present invention relates to a novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, a preparation method thereof, and a pharmaceutical composition comprising the same as an active ingredient for the prevention and treatment of metabolic disease. The novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, the optical isomer thereof, or the pharmaceutically acceptable salt thereof of the present invention has excellent activities of activating GPR40 protein and promoting insulin secretion accordingly but has no toxicity when co-administered with other drugs. That is, the novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, the optical isomer thereof, or the pharmaceutically acceptable salt thereof of the present invention can be co-administered with other drugs and can promote the activation of GPR40 protein significantly, so that the composition comprising the same as an active ingredient can be efficiently used as a pharmaceutical composition for the prevention and treatment of metabolic disease such as obesity, type I diabetes, type II diabetes, incompatible glucose tolerance, insulin resistance, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, dyslipidemia, and syndrome X, etc.
US09969719B2 Substituted 2-hydrogen-pyrazole derivative serving as anticancer drug
Disclosed is a substituted 2H-pyrazole derivative serving as a selective CDK4/6 inhibitor. Specifically, disclosed is a compound of formula (I) or a pharmaceutically acceptable salt thereof which serves as a selective CDK4/6 inhibitor.
US09969717B2 Method for producing substituted anthranilic acid derivatives
The present invention relates to a process for preparing substituted anthranilic acid derivatives of the formula (I) in which R1, R2, R3 and R4 are each as defined in the description, by conversion of compounds of the general formula (IV) in the presence of a palladium catalyst and carbon monoxide. The present invention likewise relates to compounds of the general formula (IV).
US09969714B2 Carboxylic acid compounds useful for inhibiting microsomal prostaglandin E2 synthase-1
The present invention provides compounds of Formula 1, or a pharmaceutically acceptable salts, thereof, where R, X, A, E, and G are as described herein, methods of preparing the compounds, and use of the compounds to treat pain and/or inflammation.
US09969713B2 Solid forms of 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, and their pharmaceutical compositions and uses
Solid forms comprising 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their uses are disclosed.
US09969710B2 Heteroaryl compounds as IRAK inhibitors and uses thereof
The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as IRAK inhibitors.
US09969706B2 Method of producing beraprost
An improved method is described for making single isomers of synthetic benzoprostacyclin analog compounds, in particular the pharmacologically active 314-d isomer of beraprost. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds.
US09969699B2 Cancer cell growth inhibitor, anticancer agent, and method for screening same, as well as novel compound
A cancer cell proliferation inhibitor including at least one selected from compounds represented by Structural Formulae (1) to (8), wherein the cancer cell is at least one of a cancer cell overexpressing a wild-type epidermal growth factor receptor and a cancer cell expressing an epidermal growth factor receptor mutant vIII.
US09969687B2 Compounds useful as CCR9 modulators
The present invention relates to compounds useful as CCR9 modulators, to compositions containing them, to methods of making them, and to methods of using them. In particular, the present invention relates to compounds capable of modulating the function of the CCR9 receptor by acting as partial agonists, antagonists or inverse agonists. Such compounds may be useful to treat, prevent or ameliorate a disease or condition associated with CCR9 activation, including inflammatory and immune disorder diseases or conditions such as inflammatory bowel diseases (IBD).
US09969685B2 Enantioselective synthesis of pyrroloindole compounds
Compounds according to formula (I) or (II), wherein R1, R2, and R3 are as defined in the specification, are versatile intermediates for the synthesis of DNA minor groove binder-alkylators having a cyclopropapyrroloindole (CPI) or seco-CPI alkylating subunit.
US09969684B2 N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors
The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxysulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives.
US09969679B2 Anti-proliferative compounds and uses thereof
The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, tautomers, stereoisomers, solvates, hydrates, polymorphs, and compositions thereof. Also provided are methods and kits involving the inventive compounds for treating proliferative diseases (e.g., cancers (e.g., breast cancer, prostate cancer, lung cancer, and ovarian cancer), benign neoplasms, angiogenesis, inflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound of the invention may enhance the anti-tumor immune response by inhibiting or eliminating the immune suppression mediated by immune suppressor myeloid cells (MDSCs), inducing apoptosis, and/or inhibit or down-regulate proteins (e.g., epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), estrogen receptor (ER), X-linked inhibitor of apoptosis protein (XIAP), and heat shock protein 90 (Hsp90)) in the subject.
US09969678B2 Method of producing optically active β-aminocarbonyl compound
In a method of producing an optically active β-aminocarbonyl compound using a column reactor, a column for a column reactor is charged with asymmetric catalyst particles to form a column reactor. Compounds for a Mannich-type reaction are introduced into the column reactor to be brought into contact with the asymmetric catalyst particles, to thereby convert the compounds to an optically active β-aminocarbonyl compound. The preferable asymmetric catalyst particles are resin particles that are prepared from a monomer composition containing a proline derivative monomer having an unsaturated bond and a radical polymerization initiator, and that act as a catalyst for an asymmetric Mannich-type reaction.
US09969676B1 Process for the separation of long chain amino acids and dibasic acids
There is disclosed a process for the separation of long chain amino acid and long chain dibasic acid, comprising: (1) recovering alkylamine by distilling or by extracting with an extractant solvent; (2) adding an acid an extractant solvent to the aqueous solution of step (1) to form an acidic salt of long chain amino acid to extract long chain dibasic acid; (3) separating the mixture of step (2) into an aqueous phase and an extractant phase; (4) neutralizing the aqueous phase of step (3) with an alkali hydroxide or ammonium hydroxide to obtain a crystalline solid of long chain amino acid; (5) cooling the extractant phase of step (3) to crystallize the long chain dibasic acid and recovering the dibasic acid by solid-liquid separation; and (6) recovering the extractant solvent of step (5) and isolating the alkanoic acid by distillation.
US09969663B2 Catalytic gas phase fluorination
The invention relates to a fluorination process, alternately comprising reaction stages and regeneration stages, wherein the reaction stages comprise reacting a chlorinated compound with hydrogen fluoride in gas phase in the presence of a fluorination catalyst to produce a fluorinated compound, and the regeneration stages comprise contacting the fluorination catalyst with an oxidizing agent-containing gas flow.
US09969658B2 Materials and methods for producing alkenes and derivatives thereof
The present disclosure relates to processes for production of alkene products from their alkene precursors, such as 3-hydroxyacid and alcohols, via either (1) high temperature reactive distillation with steam contact at optimal pH, (2) solvent extraction and Mulzer dehydration, (3) solid phase adsorption, desorption into an organic solvent and catalytic reaction and (4) high temperature reactive distillation with steam contact at optimal pH followed by catalytic conversion.
US09969646B2 Process for the preparation of ceramic glass material in the form of sheets, sheets thus obtained and use thereof
A process allowing to obtain ceramic glass material in the form of sheets of large dimensions usable in constructions for panelling or for flooring is described.
US09969645B2 Method for sealing an oxygen transport membrane assembly
An improved method of sealing a ceramic part to a solid part made of ceramic, metal, cermet or a ceramic coated metal is provided. The improved method includes placing a bond agent comprising an Al2O3 and SiO2 based glass-ceramic material and organic binder material on adjoining surfaces of the ceramic part and the solid part. The assembly is heated to a first target temperature that removes or dissolves the organic binder material from the bond agent and the assembly is subjected to a second induction heating step at a temperature ramp rate of between about 100° C. and 200° C. per minute to temperatures where the glass-ceramic material flows and wets the interface between adjoining surfaces. The assembly is rapidly cooled at a cooling rate of about 140° C. per minute or more to induce nucleation and re-crystallization of the glass-ceramic material to form a dense, durable and gas-tight seal.
US09969639B2 Anaerobic suspended growth treatment of contaminated water
A system may include a reactor, in which an anaerobic environment exists, that includes a slurry of at least contaminated water and a mixed bacterial culture of facultative bacteria and anaerobic bacteria. The mixed bacterial culture may be suspended within the slurry. The contaminated water may include contaminants associated with a non-metal, a metal, or a metalloid. The mixed bacterial culture may react with the contaminated water to reduce or remove the contaminants from the contaminated water to create a treated slurry. The reactor may output the treated slurry. The system may also include a filtration device to receive the treated slurry; remove, from the treated slurry, the mixed bacterial culture and the contaminants, reduced or removed from the contaminated water, to create treated water; and output the treated water. The system may also include an aeration device to add dissolved oxygen to the treated water, and output the treated water. The system may also include a reaction device where iron or aluminum salts are added to remove phosphorous, selenite, arsenate, or other contaminants which adsorb onto iron or aluminum oxyhydroxide solids. The system may also include a filtration device to remove the solids from the water, and output the treated water.
US09969636B2 Septic tank for generating methane gas
Provided is a septic tank for generating methane gas, including: a water-saving type toilet installed in a restroom of a building and discharging excreta of users, wherein high-density excreta is discharged from the water-saving type toilet by using a reduced amount of water to discharge the excreta; an excreta storage tank buried underground and connected to the water-saving type toilet to store the excreta discharged from the water-saving type toilet; a heating unit for heating the excreta storage tank so as to increase a fermentation speed of the excreta in the excreta storage tank; a methane gas supply unit for collecting and discharging methane gas generated as the excreta in the excreta storage tank is fermented; and a gas storage tank connected to the methane gas supply unit to store the methane gas discharged from the methane gas supply unit.
US09969635B2 Downflow denitrification system
In general, the present invention is directed to systems for treating water or wastewater. In accordance with some embodiments of the present invention, the system may utilize a vessel with a plurality of filter beds, at least one inlet, and at least one outlet, and the system may include: a first filtration bed comprising a first granular and/or angular media, the first media having a high surface area and configured for biological and physical treatment of the water or wastewater; a second filtration bed including a second granular and/or angular media, the second media having a lower surface area than the first media; wherein the water or wastewater enters the vessel via the at least one inlet, flows through the first filtration bed and the second filtration bed, and exits the vessel through the at least one outlet.
US09969634B2 High-capacity biological contact rotor
The present invention relates to a shaft/frame system for high capacity rotors for wastewater treatment for sanitation purposes and to reduce the pollutant organic load; of the type formed by a drive shaft with supports at the ends and for its coupling to a drive motor, comprising a plurality of intermediate annular collars and two end annular collars distributed equidistantly from one another, adapted to fixedly receive a plurality of radially distributed structural arms, characterized in that said structural arms are substantially T-shaped and are joined each other to form rings adapted to receive and fix each other, packs of media consisting of a plurality of biomass support sheets, which are self-supported by four tubes fixed in T-shaped structural elements; wherein said tubes are hollow, and internally accommodate a volume of air and are obturated at both ends by means of plugs, with one or more threaded blind bore(s) adapted to receive the fixation means, with which it is fixed to the T-shaped structural elements, which exert a buoyancy force when turning the rotor by effect of the contained air. In addition to have elements that helps to the resistant bonding with reduced stresses in the T-shaped structure.
US09969633B2 Systems and methods for treating oil, fat and grease in collection systems
The present invention relates to apparatus, methods, and applications for treating wastewater collection systems contaminated with fats, oils and grease (FOG), such as wet wells, transfer or lift stations, or main sewer lines, and more particularly to biological processes for removing the FOG from wastewater. This invention further relates to apparatus and methods for growing microbes on-site at a wastewater treatment facility or FOG-contaminated wastewater collection system location, and for economically inoculating sufficient microbes to solve various treatment problems rapidly.
US09969626B2 Techniques for increasing the evaporation rate in evaporation ponds
A system for enhancing evaporation from a body of liquid, in which heated or unheated air is distributed through a pipe network that is submerged in the evaporation pond, with the air being injected into the pond to produce air bubbles in the water. The air may be combined with water prior to the injection. The water may be drawn from the pond. The air and/or water may be heated by solar heating, electric heating, fuel burning, or waste heat recovery. In the case of solar heating, any of a transpired solar collector, a packed bed solar collector, a flat plate solar collector, a linear Fresnel collector, a parabolic solar collector, a paraboloid dish solar collector, or other could be used. The pipe network may be maintained at a desired depth below the upper surface of the pond by various means, with one example being flotation devices, from which the pipe network is suspended.
US09969613B2 Method for forming micro-electro-mechanical system (MEMS) beam structure
Micro-Electro-Mechanical System (MEMS) structures, methods of manufacture and design structures are disclosed. The method includes forming a Micro-Electro-Mechanical System (MEMS) beam structure by venting both tungsten material and silicon material above and below the MEMS beam to form an upper cavity above the MEMS beam and a lower cavity structure below the MEMS beam.
US09969610B2 Wafer level MEMS package including dual seal ring
A microelectromechanical systems (MEMS) package includes a substrate extending between a first pair of outer edges to define a length and a second pair of outer edges to define a width. A seal ring assembly is disposed on the substrate and includes at least one seal ring creating a first boundary point adjacent to at least one MEMS device and a second boundary point adjacent at least one of the outer edges. The package further includes a window lid on the seal ring assembly to define a seal gap containing the at least one MEMS device. The seal ring assembly anchors the window lid to the substrate at the second boundary point such that deflection of the window lid into the seal gap is reduced.
US09969609B2 MEMS device
The present disclosure provides a method for forming micro-electro-mechanical-system (MEMS) devices. The method includes providing a plurality of wafers; bonding a front surface of at least a first wafer onto a front surface of a second wafer; trimming an edge of and thinning the at least first wafer after the at least first wafer is bonded onto the second wafer; and bonding a first supporting plate onto a front surface of a third wafer. The method further includes thinning a back surface of the third wafer and forming alignment marks on a thinned back surface of the third wafer; bonding a second supporting plate onto the thinned back surface of the third wafer according to the alignment marks; and removing the first supporting plate and bonding the at least first wafer onto the third wafer according to the alignment marks to form a stack structure.
US09969607B2 Microelectromechanical device and method for manufacturing it
A device and method utilizes interconnecting layers separated by an insulating layer. A layered structure comprises a first and a second layer of electrically conductive material, and a third layer of electrically insulating material between them. A via trench is fabricated that extends from the second layer through the third layer into the first layer, a surface on the first layer of electrically conductive material forming a bottom surface of the via trench. An ink-jetting set-up for a mixture of liquid carrier and nanoparticles of conductive material is formed, and a specific process period is determined. Capillary flow of nanoparticles to peripheral edges of an ink-jetted blob of said mixture is induced. The mixture is ink-jetted into a blob on the via trench; the layered structure is heated to evaporate the liquid carrier. The interconnection element is higher at a certain point than between opposing side walls.
US09969605B2 Liquid natural gas gun-style nozzle
There is disclosed a high pressure dispensing nozzle for providing cryogenic fuel such as liquid natural gas (LNG) from a source to a filling receptacle, such as on a vehicle. The nozzle has a gun-style nozzle construction and a plurality of jaw members provided near a distal end for locking engagement with the filling receptacle. The nozzle further has a movable internal poppet to establish a fuel passageway through the nozzle for delivery of fuel therethrough. Two different triggers enable separate steps of locking of the nozzle onto the filling receptacle and initiating gas flow for ease of use. The two steps may also me combined and actuated by a single trigger. One nozzle disclosed includes a safety button for dispersing residual gas in the nozzle prior to disengagement to help avoid injury to the user.
US09969602B2 Insulated boom knuckle cover for high voltage line truck
An insulated boom knuckle cover for high voltage line truck includes an insulating sheathing unit disposed for expedient attachment to a boom arm of a high voltage line truck. The sheathing unit includes an upper section, attachable to the boom arm at a position proximal a knuckle of the boom arm, and an arched knuckle cover section disposed depending from the upper section. The arched knuckle cover section includes a lowermost portion disposed to overlie the knuckle of the boom arm when the boom arm is disposed in a lowered, folded position, and yet maintain appropriate coverage of the knuckle when the boom arm is also extended away from the lowered, folded position. The present invention therefore prevents direct contact of high voltage lines with the knuckle, or portions of the boom arm proximal the knuckle, and shields the knuckle from arcing.
US09969588B2 Sheet alignment device and image forming apparatus
A sheet alignment device includes a driven roller, a drive roller, a displacement driving device, an information acquisition portion, and a displacement control portion. The drive roller is configured to rotate in a first rotation direction and in contact with an upper surface of each of sheets conveyed onto a tilt tray, to feed the sheets toward a base end portion of the tilt tray. The drive roller is configured to rotate in a second rotation direction and in contact with an uppermost surface of the sheets, to discharge the sheets from the tilt tray. The displacement control portion is configured to, when the drive roller rotates in the first rotation direction, control a holding position of the drive roller in accordance with the number of the sheets on the tilt tray and thickness information of each of the sheets acquired by the information acquisition portion.
US09969575B2 Trailer stabilizer and restraint
A trailer restraining device comprising a portable frame having mounted thereto a tail hook and a king pin receiver that includes at least one of a receiver hydraulic cylinder, a receiver pneumatic cylinder, a receiver electric actuator, and a receiver winch.
US09969571B1 Container stacking configurations
The disclosure describes, in part, a system and method for improving the stacking of containers on or in a transportation unit. In some implementations, a stacking configuration may be planned that identifies containers and a position for those containers in the stacking configuration. The stacking configuration may be planned based on dimension values of the containers such that when stacked the stacking configuration remains stable. In addition, to improve the efficiency at which containers may be stacked, the disclosure describes that containers and/or the picking of items for those containers may be sequenced so that the containers, when packed and routed, arrive in a manner that allows efficient stacking.
US09969566B1 Magnetic singulator for bulk rail fasteners
A singulator is provided for orienting, sorting and conveying at least one rail fastener, from a bulk supply of such fasteners, and includes a frame defining a lower end and an upper end. A plurality of transverse magnet bars is connected to an endless conveyor system disposed on the frame to move from the lower end to the upper end. A ramp is disposed on the frame, has an underside facing the magnet bars, and an opposite sorting surface opposite the underside and receiving the fasteners. At least one deflector assembly is associated with the ramp and is constructed and arranged for sorting fasteners drawn along the ramp by the magnet bars from the lower end to the upper end so that single fasteners are delivered at the upper end.
US09969553B2 Hopper apparatuses for processing a bulk solid, and related systems and methods
A hopper apparatus comprises a movable wall comprising opposing walls movably connected to a support assembly and oriented at acute angles relative to a central vertical axis of the support assembly, and movement control devices configured and positioned to move the opposing walls along the support assembly to control dimensions of a discharge outlet at least partially defined by converging ends of the opposing walls; a liner assembly comprising liner structures at least partially overlying inner surfaces of the opposing walls and configured to remain at least partially stationary relative to the opposing walls during movement of the opposing walls; and pressure sensors between the inner surfaces of opposing walls and portions of the liner structures thereover. A bulk solids processing system and a method of processing a bulk solid are also described.
US09969552B2 Automated system for transporting payloads
An automated warehouse storage system including a multilevel storage array is provided. Each aisle has a set of storage levels and each level has storage locations distributed along the aisle. The guideway network extending through the multilevel storage array is configured for autonomous vehicles to move along the guideway network within the multilevel storage array. The guideway network including an inter-aisle guideway spanning at least two of the multiple aisles and a set of guideway levels extending in an aisle of the multiple aisles and disposed so that each guideway level is at a different one of the storage levels and the vehicles on the guideway level can access the storage locations distributed along the aisle. Each set of guideway levels is connected to the inter-aisle guideway forming a common guideway path so that a vehicle can move between inter-aisle guideway and each guideway level along the common guideway path.
US09969546B2 Single serve capsule comprising a filter element connected thereto by sealing
The present invention relates to a single serve capsule for preparing a beverage, comprising a side wall and a bottom, which together define a space, a filter element being sealed to the bottom within said space.
US09969544B2 Pressurised refill canister with an outlet valve
A pressurized refill canister containing a composition including a propellant. The canister has an outlet valve having a stem biased to a closed position by a first resilient member. The stem has a maximum outer diameter of greater than 3 mm. At the outlet end of the stem, at least part of the wall of the stem extends inwardly from the outside diameter for at least 50% of the radius.
US09969529B2 Easy open plastic bags
A woven laminated plastic bag having an easy open feature is provided. The easy open feature is generally defined by a weakened portion in the bag. In various aspects the bag can be fabricated from woven polypropylene and/or polyethylene layer which can be laminated with a film layer, can form a pinch bottom bag, and can have one or both sides include graphics and/or printing. The bag can also provide a top end and/or a bottom end either or both of which provide a discrete area which may contain discrete graphics and/or printing.
US09969525B2 Stand for machine components
A stand is disclosed for supporting a moldboard and a drawbar of a grading machine. The stand may comprise a base frame and a component support unit. The said stand may be configured to support the moldboard, and the component support unit may be configured to support at least a portion of the drawbar. The base frame and the component support unit may be configured to: (a) support a substantial portion of the moldboard above the base frame; and (b) support a substantial portion of the drawbar above the base frame and the moldboard when the moldboard is supported on the stand.
US09969522B2 Foldable box template
A foldable box template includes first, second, third, fourth, and fifth segments. Each of the segments has a length, a width, and one or more flaps. The first segment is positioned at a first end of the template and the fifth segment is positioned at a second, opposing end of the template. The sum of the lengths of the first segment and the fifth segment is generally equal to the length of the third segment. As a result, the first and fifth segments form a seam on a sidewall of a box formed from the box template. In some cases, the seam formed by the first and fifth segments is offset from seams formed in top and bottom surfaces of the box. The seam formed by the first and fifth segments is offset from a corner of the box.
US09969518B2 Semi-automatic syringe label applicator
A label applicator for applying a label to a cylindrical portion of an object may comprise a roller and a label handler, with the roller rotating the object to which the label is being applied and the label handler separating a label from its backer and extending the label towards the object being rotated by the roller. The distance between the label handler and the object rotated by the roller is less than a length of the label. The label applicator may further comprise a printer, such as a thermal transfer printer, which may be configured to print labels for a plurality of objects to which different labels are applied consecutively.
US09969517B2 Systems and methods for handling plastic containers having a deep-set invertible base
A plastic container comprises an upper portion including a finish defining an opening into the container, a lower portion including a base defining a standing surface, a sidewall extending between the upper portion and the lower portion, the sidewall defining a longitudinal axis, and at least one substantially transversely-oriented pressure panel located in the lower portion. The pressure panel is movable between an outwardly-inclined position and an inwardly-inclined position to compensate for a change of pressure inside the container. The standing surface defines a standing plane, and the entire pressure panel is located between the standing plane and the upper portion of the container when the pressure panel is in the outwardly-inclined position.
US09969516B2 Packaging including pouch for container
A pouch, designed to be attached, either directly or indirectly, to a container, is provided with two end portions, each of which is formed with an elongated slit. When the pouch is directly attached atop a container, the end portions are pulled over the lid and catch a rim portion of the container. When the pouch is placed upon a lid covered container, the end portions of the pouch can catch or engage the lid. In accordance with an aspect of the invention, a pair of spaced slits extends from each elongated slit, thereby creating a tab or flap in each end portion. The flap is configured to either directly catch a rim of the container or be tucked under the lid, i.e., between the lid and the container, to attach the pouch to the lid and, indirectly, the container.
US09969514B2 Orientation-based hashing for fast item orientation sensing
Technologies are generally described for orientation-based hashing to determine item orientation. In some examples, a conveyance system may be configured to adjust the orientations of various types of items before sorting. The conveyance system may include a computer vision system that determines whether the orientation of an item should be adjusted based on an item-feature hash table that relates item image features to item orientations or actuator signals. In other examples, the computer vision system may determine item image features associated with a particular item and perform an item-feature hash table lookup using the item image features to determine an item orientation or actuator action. The item-feature hash table may be separately trained, allowing the computer vision system to rapidly determine the appropriate item orientation or actuator action.
US09969501B2 Aircraft fuel tank arrangement
An aircraft fuel tank arrangement for the relief of a pressure differential between the interior of the aircraft fuel tank and the ambient atmosphere is provided. The aircraft fuel tank arrangement comprises a removable cartridge received within a cartridge-receiving body located at least partially in the fuel tank, said cartridge comprising a first burstable member operable to rupture in the presence of a pressure differential between the interior of the aircraft fuel tank and the ambient atmosphere which is greater than a predetermined pressure differential.
US09969493B2 Aerodynamic lifting device
An aerodynamic lifting device comprises a chassis (200); a rotor (120) having a rotational axis (R) and a plurality of rotor blades (123) disposed in an annular ring about the rotational axis (R) supported by the chassis (200); and a torque transmission means (126,130,139) to provide tractive force for rotating the rotor (120). The torque transmission means (126,130,139) co-operates with at least one complementary and circumferentially extending drive surface (126a, 126b) of the rotor (120) to transmit tractive force as tangential forces and resultant torque sufficient to drive the rotor (120) and thereby generate lift. The aerodynamic lifting device may be used in airborne craft which may be deployed for waterborne use with a buoyant chassis (200), especially of toroidal shape, for elevating the rotor (120) above a water surface (300) during take off and landing.
US09969478B2 Remote controlled boat system
The invention generally relates to a remote controlled boat system. In certain embodiments, the system includes a boat having a first central processing unit operably coupled to a communication unit and a first global positioning unit operably coupled to the first central processing unit. The system also includes at least one controller configured to control the boat via remote communication with the first central processing unit via the communication unit of the boat, the controller including a second central processing unit operably coupled to a second global positioning unit.
US09969477B2 Engine control device
An engine control device is provided with a main operation unit, an auxiliary operation unit, a changeover switch, and an engine control unit. The main operation unit is capable of performing an operation of changing a rotation speed of a propulsion engine mounted on a ship. The auxiliary operation unit is capable of performing an operation of changing the rotation speed of the engine instead of the main operation unit. The changeover switch is capable of performing an operation of switching between a main ship handling state in which the rotation speed of the engine can be changed by operating the main operation unit and an auxiliary ship handling state in which the rotation speed of the engine can be changed by operating the auxiliary operation unit. The engine control unit stops the engine when the changeover operation unit is operated to switch from the auxiliary ship handling state to the main ship handling state.
US09969466B2 Method for operating floating driller
A method for operating floating vessel wherein the floating vessel comprises a hull having: a bottom surface, a top deck surface, at least two connected sections engaging between the bottom surface and the top deck surface, and at least one fin extending from the hull with an upper fin surface sloping towards the bottom surface and secured to and extending from the hull, the at least one fin configured to provide hydrodynamic performance. The at least two connected sections extend downwardly from the top deck surface toward the bottom surface. The at least two connected sections contain at least two of: an upper portion in section view with a sloping side extending from the top deck section, a cylindrical neck section in profile view, and a lower conical section in profile view with a sloping side extending from the cylindrical neck section.
US09969457B2 Interchangeable front fork mechanism
A bicycle apparatus with interchangeable front fork is disclosed. The bicycle comprises a frame and a quick release assembly for securing the removable front fork attachment assembly to the bicycle frame's head tube. The interchangeable front fork attachment assembly and quick release assembly allows for the quick interchanging of front fork with varying attachments which utilize different methods to achieve motion.
US09969455B2 Frame for bike and electric bike having the same
A frame for a bike with a plurality of frame units coupled to each other, at least one of the plurality of frame units includes a hollow chamber, and a first partition wall that partitions the hollow chamber into a first chamber unit and a second chamber unit, wherein the first chamber unit includes an opening in a first side of the first chamber unit and an accommodation space to accommodate a battery pack, and wherein the second chamber unit includes a plurality of holes through a first side of the second chamber unit, an interior of the second chamber unit and an exterior of the frame for the bike being in fluid communication through the plurality of holes.
US09969454B2 Vehicle
A load transmission includes a left foot placement surface on which a left foot of a driver riding the vehicle is to be placed and a right foot placement surface on which a right foot of the driver is to be placed. The load transmission transmits a load to a left portion of a linkage by way of the left foot placement surface, and transmits a load to a right portion of the linkage by way of the right foot placement surface.
US09969443B2 Reinforcing structure of vehicle body
There are provided a floor panel, a tunnel portion which is provided to protrude at the floor panel, a pair of right-and-left tunnel side frames, a pair of right-and-left floor frames, and a band plate which is made from carbon fiber reinforced plastic, an inward end portion which being connected to the tunnel side frame and an outward end portion of which being connected to the floor frame, wherein the band plate portion includes a first displacement following portion which is configured to be displaced, following displacement of the tunnel side frame and a second displacement following portion which is configured to be displaced, following displacement of the floor frame, and the first displacement following portion and the second displacement following portion are configured to be asymmetrical relatively to a longitudinal-directional axis.
US09969440B2 Joining structure of vehicle framework members
A joining structure of vehicle framework members includes: a first vehicle framework member formed by a lightweight metal material having a rectangular closed cross section shape in a sectional view orthogonal to an extension direction of the first vehicle framework member; a second vehicle framework member formed by a lightweight metal material having a hat shape in the sectional view orthogonal to the extension direction, the second vehicle framework member covering the first vehicle framework member; an offset flange portion that is a portion of a flange portion formed at an end portion at the opening side of the second vehicle framework member, and that protrudes to an opposite side of the flange portion from the opening side; and a protrusion portion that protrudes from an end portion of the offset flange portion at the opening side, and that is joined to the first vehicle framework member by heat-welding.
US09969436B1 Retractable mud flap system
The retractable mud flap system comprises two tracks, a chute, and a flap carrier. The invention is used to retract and extend a mud flap on a truck and is commonly used in pairs of two so that a mud flap on each side of the truck may be retracted. The retractable mud flap system attaches to the underside of a truck's dump bed or to extensions of the truck frame above the rear wheel. The flap carrier comprises two roller assemblies and a flap clip. A mud flap is coupled to the flap clip and passes through the chute. The roller assemblies move on the tracks with the flap clip mounted between them. A control located within the cab activates a motor on one roller assembly, moving the roller assemblies and the mud flap. A remote control embodiment is also described.
US09969432B2 Vehicle body front structure
A vehicle body front structure includes left and right extension side mount members that are provided at rear ends of left and right bumper beam extensions of a front bumper beam and left and right front side frames whose front ends are coupled with the left and right extension side mount members, respectively. The vehicle body front structure further includes left and right gussets that are positioned on left and right corners between outer surfaces in a vehicle width direction of rear end portions of the left and right bumper beam extensions and the left and right extension side mount members, respectively. The left and right gussets are joined to the left and right bumper beam extensions, respectively. Strength of the left and right gussets is higher than strength of the left and right bumper beam extensions.
US09969425B2 Rear wheel steering control
A rear wheel steering system in a vehicle. The system includes a rear wheel steering actuator, a vehicle speed sensor, and an electronic control unit. The rear wheel steering actuator is coupled to a rear wheel of the vehicle and controls a steering angle of the rear wheel. The electronic control unit is coupled to the rear wheel steering actuator and the vehicle speed sensor and is configured to determine a speed of the vehicle and to limit the steering angle of the rear wheel based on the speed of the vehicle and a fault tolerant time of the rear wheel steering system.
US09969421B2 Energy absorption device for a steering column
An energy absorption device for a steering column for a motor vehicle may include a bending bracket for energy absorption in a crash event. The bending bracket may comprise a first fastening element and a second fastening element, with the first fastening element being displaceable relative to the second fastening element if, in a crash event, the bending bracket is deformed along a guide track delimited by a start and an end. The energy absorption device may further include one or more collision elements arranged on the guide track. An example collision element may interact with the first fastening element or an element on a retaining part that is secured to the first fastening element such that the collision element, the first fastening element, and/or the element on the retaining part are deformed and absorb additional energy.
US09969417B2 Stroller capable of being folded twice
The present disclosure provides a stroller capable of being folded twice, comprising: side support assemblies located at two sides and at least one transverse brace connected between the side support assemblies of the two sides, the side support assembly at each side comprises a push rod, a front wheel support and a rear wheel support which are rotatably connected to each other, and in a first folded state, the push rod, the front wheel support and the rear wheel support are rotated to be in a closed state; each transverse brace has a first transverse folding rotation point and a second transverse folding rotation point. The stroller is capable of achieving not only a first folding, but also a second folding of the two side support assemblies, so as to reduce the volume occupied by the entire stroller in these states.
US09969412B2 Expedition carts and associated methods
Exemplary embodiments of an expedition cart are provided. The expedition cart includes a chassis configured and dimensioned to support a load. The expedition cart includes first and second gusset plates attached to the chassis. Each of the first and second gusset plates includes a central body portion and curved fastening edges on either side of the central body portion. The curved fastening edges can be configured and dimensioned to mate against at least a portion of the chassis. Exemplary embodiments of an expedition cart are also provided that include first and second hubs engaged with the chassis, the first and second hubs defining either a single part or a two part design.
US09969410B2 Railway safety critical systems with task redundancy and asymmetric communications capability
A railway safety critical application system substitutes commercial off-the-shelf (COTS) hardware and/or software for railway-domain specific product components, yet is validated to conform to railway safety critical system failure-free standards. The safety critical system uses a pair of tasks executed on a controller of a COTS personal computer or within a virtual environment with asymmetric communications capability. Both tasks receive and verify safety critical systems input message data and security code integrity and separately generate output data responsive to the input message. The first task has sole capability to send complete safety critical system output messages, but only the second task has the capability of generating the output security code. A failure of any of systems hardware, software or processing capability results failure to transmit a safety critical system output message or an output message that cannot be verified by other safety critical systems.
US09969401B2 Clickable hand control device in a vehicle
There is provided a hand operable device for handicapped persons driving a car. More particularly, there is provided a hand operated device for actuating vehicle acceleration and brake pedals. The device includes a brake bar having in a first end attaching means for attachment to a brake pedal of the vehicle, said brake bar having in a second end a joint to a handle bar for transversely supporting the brake bar. The handle bar is provided with means for electronically regulating the speed of the vehicle and attachment means for releasably attaching the handle bar via a mounting piece to (or near) the steering column without the use of tools.
US09969396B2 Control strategy for unoccupied autonomous vehicle
An automotive vehicle includes traction wheels, a powertrain configured to transmit drive power to the traction wheels, a sensor configured to detect a presence of an occupant, an actuator configured to control vehicle steering, acceleration, braking, or shifting, and at least one controller configured to automatically control the actuator based on an automated driving system algorithm. The powertrain is selectively operable in a first mode having a first operating characteristic and a second mode having a second operating characteristic. The controller is further configured to control the powertrain in the first mode in response to the sensor detecting an occupant being present and the actuator being controlled based on the automated driving system algorithm, and in the second mode in response to the sensor detecting no occupant being present and the actuator being controlled based on the automated driving system algorithm.
US09969395B1 Lash mitigation
A motor vehicle propulsion system, an engine control system, and a method for starting an engine of a motor vehicle system are provided, which are configured to request an engine restart after stopping the engine, decrease a K-factor in a torque converter coupling within 1.5 seconds of requesting the engine restart, and to increase the K-factor in the torque converter coupling to minimize the lash and disturbance between interconnecting components in a vehicle system during negative torque vehicle driving to positive torque propulsion system driving transitions where a torque converter exists.
US09969381B2 Control apparatus for hybrid vehicle
A control apparatus for a hybrid vehicle controls a hybrid vehicle, the hybrid vehicle including: a power source including an internal combustion engine and an electric; a recirculating device configured to recirculate an exhaust gas from an exhaust side to an intake side of the internal combustion engine; and a recirculation amount adjusting device configured to adjust an amount of the recirculation by the recirculating device. The control apparatus for a hybrid vehicle is provided with: a determining device configured to determine whether or not the internal combustion engine is stopped and electric running by the electric motor can be performed if the hybrid vehicle runs while operating the internal combustion engine; and a recirculation controlling device configured to control the recirculation amount adjusting device such that the amount of the recirculation by the recirculating device is larger than an amount when it is determined that the electric running cannot be performed, if it is determined that the electric running can be performed. This makes it possible to preferably prevent a misfire of the internal combustion engine.
US09969378B2 Determining integrity of braking control system
A method of determining the integrity of an electric or hydraulic braking control system. A reduction rate of a voltage or hydraulic pressure in the braking control system is determined, and the integrity of the braking control system is determined by comparing the reduction rate with a threshold. The braking control system may be an aircraft braking control system, and the method may be performed during flight of the aircraft—typically during cruise.
US09969377B2 Center bearing of adapter plate comprising rubber and rigid plastic members developed for spring brake actuators
This invention is related to improving the sealing of the adapter plate inside the spring brake actuator and to improving the bearing of the intermediate shaft and the adapter plate. The invention is related to a new design regarding the bearing section providing sealing between the intermediate shaft and the adapter plate, which is a part of the spring brake actuator. The present invention is related to the development of two pieced bearing member having different hardness and being produced from different materials one of which is a rigid plastic piece which prevents force losses and decreases lateral loads, and the other of which is the rubber means.
US09969376B2 Brake booster device for a braking system of a vehicle and a manufacturing method for a brake booster device for a braking system of a vehicle
A brake booster device is provided for a braking system of a vehicle having an input rod component, which may be situated relative to a brake actuation element in such a way that the input rod component is adjustable with the aid of a driver brake force exerted on the brake actuation element, and having a guide body with a bore formed therein, into which the input rod component at least partially protrudes, an initial spring being compressibly arranged between an inner wall of the bore in the guide body and a widened intermediate section of the input rod component, and the initial spring being constrained with the aid of a captive spring mount.
US09969374B2 Control and delivery of hydraulic fluid in vehicle braking system
A braking system in a hybrid vehicle is provided. The braking system includes a master cylinder having a first outlet, a second outlet, and a piston disposed therein and translatable from a proximal end to a distal end in response to brake pedal displacement. A brake fluid reservoir supplies hydraulic fluid to the master cylinder. A first fluid circuit connects the first outlet of the master cylinder to the brake fluid reservoir. A second fluid circuit connects the second outlet of the master cylinder to wheel brakes and supplies hydraulic fluid from the master cylinder to the wheel brakes in response to brake pedal displacement. The first outlet of the master cylinder is disposed between the second outlet and the proximal end of the master cylinder such that initial brake pedal displacement transfers brake fluid from the master cylinder to the fluid reservoir to inhibit hydraulic braking during regenerative braking.
US09969365B2 Carwash with smartphone proximity detection
An example carwash method involves a customer using a smartphone with an app for finding participating carwash locations, making online payments for select carwash options, and then using the smartphone app to start the washing process when the customer arrives at the carwash. Various means can be used for determining when the vehicle is at the carwash entrance. Examples of such means include, but are not limited to, reading the GPS coordinates of the smartphone in the vehicle; establishing Bluetooth, WiFi or some other limited-range wireless communication link between the smartphone and the local carwash controller; displaying and manually entering a code or password at the carwash; and scanning a QR code displayed on the smartphone. During the carwash operation, in some examples, the smartphone app provides the customer with an emergency stop option.
US09969364B2 Touchless vehicle wash with conveyer system
A touchless vehicle wash for washing a vehicle is provided comprising: a conveyor for contacting a wheel of the vehicle and propelling the vehicle through a wash tunnel; an structure, the structure including a first side vertical member, a vertically adjustable horizontal member in slidable engagement with the first side vertical member, an optional second side vertical member, an at least one vertical sensor for mapping an upper surface of the vehicle, an at least one horizontal sensor for mapping a front and a back of the vehicle, a first series of high pressure spray nozzles on the first side vertical member, fixedly positioned at a distance from the conveyor and a top series of high pressure spray nozzles adjustably positioned on the vertically adjustable horizontal member; an actuator for vertically adjusting the horizontal member; a second side sensor for sensing a second side; a positioner operatively connected to the sensor; and a second side vertical member connected to the actuator, the second side vertical member including a second series of high pressure spray nozzles, the first, top and second series of spray nozzles configured to be between about 12 inches to about 22 inches from the vehicle in use.
US09969360B2 Wiper connector and wiper assembly thereof
A wiper connector and a wiper assembly thereof. The connector is detachably coupled between a wiper arm and a wiper, wherein the connector comprises a connector body and a stopper. The connector body has a longitudinal groove. One end of a stopper is detachably and rotatably disposed at one end of the longitudinal groove, and the other end of the stopper is detachably retained to the longitudinal groove so that the stopper movably shields a part of an opening of the longitudinal groove.
US09969355B2 Integrated circuit device and method for dual-mode transponder communication
In an embodiment, an integrated circuit (IC) device is disclosed. In the embodiment, the IC device includes a load modulation module, a current source coupled to the load modulation module, an interface to a resonant circuit, the interface coupled to the load modulation module and the current source, and an interface to a charge source, the interface coupled to the current source, wherein the load modulation module is configured to provide a signal for transmission by modifying the load through the load modulation module, and wherein the current source is configured to provide a signal for transmission by generating pulses of current.
US09969353B2 Force-limiting device for a seat belt system
A force-limiting device (4) for a seat belt device having at least two parts (5, 11, 15) controlled with a frequency-dependent, defined movement for energy absorption, wherein the parts (5, 11, 15) that move the parts (5, 11, 15) undergo an undulating movement (Q) directed perpendicular to the feed movement (V) in the course of which the gearings (8, 10, 18, 19) alternatingly engage and disengage. An open spring washer exerts force to move the parts (5, 11, 15) toward one another and can be automatically increased after a preset belt extraction length. The spring washer (6) applies a varying spring force to the parts (5, 11, 15) moving toward one another during the movement.
US09969351B2 Side airbag device-installed vehicle seat
A side airbag device-installed vehicle seat including: a side frame; a side airbag main body that is partitioned into a front bag section and a rear bag section, and in which a front portion of the rear bag section is positioned further toward the seat front side than the front flange portion at least in an inflated and deployed state; and an inner bag section that extends out from the front portion of the rear bag section, past a seat front of the front flange portion, and to a seat width direction inner side of the side frame, and in which an internal portion of the inner bag section in communication with the inside of the front portion of the rear bag section is supplied with gas from the inflator and inflates within the side section.
US09969350B2 Dual-chambered passenger airbag
An airbag includes an outer shell defining an interior, at least one vent opening structured to enable fluid communication between the interior and an exterior of the airbag, and a divider dividing the airbag interior into an upper chamber and a lower chamber. The divider is deflectable in a first direction toward the lower chamber and in a second direction toward the upper chamber. A vent cover is coupled to the at least one vent opening and to the divider so as to close over and restrict a flow of gas through the at least one vent opening when the divider is deflected in the first direction, and so as to permit the vent cover to open so as to enable an unobstructed flow of gas through the at least one vent opening when the divider is deflected in the second direction.
US09969337B2 Methods and systems for mobile-agent navigation
Feature detection may be performed on an image. After feature descriptors for each detected feature are computed, feature matching between feature descriptors for the current image and for a key image frame is performed. If a sufficient number of good matches are identified, key points associated with the feature correspondences may be projected from image coordinates to world coordinates. A distance, in the world coordinate frame, between each feature correspondence may he computed. When the computed distances indicate sufficient movement of the mobile agent to ensure accurate motion estimation, a motion estimate may he computed from the pairs of world coordinates associated with the feature correspondences. A current camera pose in a global coordinate frame may be generated. A motion trajectory may then be determined and feature descriptors for the key image may be updated to the feature descriptors for the current image frame.
US09969330B2 Mirror substitute device and vehicle
A mirror substitute device for a vehicle has at least one camera designed to cover at least a part of the surroundings of the vehicle and to provide a corresponding image signal, an image processing device coupled to the camera and designed to process the image signal and to output a processed image signal, and at least one display device designed to display the processed image signal.
US09969318B2 Locking system for securing a container
A lock for securing a container includes a lock platform, a coupler including a portion that is disposed above the lock platform, an interaction member associated with the coupler, and a linkage mechanism including an actuation device and an actuation surface. The actuation surface is curved or sloped. In addition, movement of the actuation device causes movement of the interaction member along the actuation surface in a first direction such that the coupler automatically secures the container to the lock.
US09969317B2 Multi-application vehicular retention system
A utility land vehicle is provided having a cargo compartment that includes a retention system. One embodiment of the retention system includes latch and receiver assemblies. The latch assembly includes first and second latches. The first and second latches are spaced apart from each other. A tie attached to each of the first and second latches actuates to cause both first and second latches to release. The receiver assemblies comprise first and second receivers. Each of the first and second receivers includes a body and a slot formed in the body. Each of the slots formed in each body of each of the first and second receivers includes an opening wherein the opening of the slot formed in the body of the first receiver faces the first latch, and the opening of the slot formed in the body of the second receiver faces the second latch.
US09969316B2 Dunnage bag arrangement
Various embodiments of the present disclosure provide a dunnage bag arrangement for securing loads. The dunnage bag arrangement includes an inflatable dunnage bag having a gastight inflatable bladder, a top edge, a bottom edge, a first side edge and a second side edge; and at least one inflation valve adapted for inflating the gastight inflatable bladder and being located along the first side edge and/or the second side edge.
US09969313B2 Trailer with tilt system
A trailer including an axle assembly which travels horizontally beneath the trailer, transforming the trailer from a transport position to a loading position. The axle assembly is connected to a tail rod which connects with a tail ramp located at the rear of the trailer. As the axle assembly travels forward, the tail rod is removed from the tail ramp, causing the ramp to tilt down towards the ground away from the trailer bed, allowing a vehicle to be driven up over the ramp and onto the bed of the trailer. A hitch assembly allows the hitch to move in relation to the trailer, preventing damage to a towing vehicle.
US09969305B1 Swiveling child safety seat
The swiveling child safety seat that is adapted to be positioned on a seat of a vehicle, and which is able to pivot about a vertical axis. The swiveling child safety seat is further defined with a stationary seat base that is adapted to be secured to the seat of the vehicle. A swiveling child seat is pivotably engaged to the stationary seat base. The swiveling child seat is further defined with a rear surface that includes an armature track that extends laterally across the rear surface. The stationary seat base includes an anti-tilt catch that interacts with the armature track to ensure that the swiveling child seat is properly secured to the stationary seat base. The swiveling child seat includes a pivoting pin that extends downwardly from a bottom surface and engages the stationary seat base.
US09969302B2 Walk-in seat
A walk-in seat includes: a lower arm; an upper arm; a reclining mechanism; a shaft, which is rotatably provided to the lower arm; an operating lever, which is rotated with interlocking with the walk-in lever that is rotated by the walk-in operation; a rotation facilitating lever, which causes the shaft and the operating lever to further rotate with interlocking with a forward tilting operation of the upper arm; a stopper lever, which is held in the shaft with a play in a rotation direction and has a stopper portion; an insertion hole, through which the stopper portion being inserted; and a restriction portion, which is provided to the upper arm and abutted against the stopper portion to restrict a forward tilting operation of the upper arm to a predetermined amount.
US09969297B2 In-service fuel cell performance recovery
The performance of a fuel cell power plant that decays, in an electric vehicle which makes frequent starts, is recovered by partially shutting down the power plant. Recovery is enabled by a recovery enable flag upon conditions such as vehicle using low or no power, vehicle speed at or near zero, electric storage SOC above a threshold, and no recovery during the last half-hour (or other duration). The recovery restart resets a timer to ensure that recovery is not attempted too often. The power plant then remains in a recovery stand-by mode until a recovery restart flag is set to 1. The restart causes start-up of the fuel cell power plant, reaching an operational mode.
US09969289B2 System and method for monitoring coordination/control of multi-output integrated charger for electric automobile
A system and method for monitoring coordination/control of a multi-output integrated charger for electric automobiles, comprising a voltage/current demand collection module, an optimal-policy design module, and a policy execution module. The voltage/current demand collection module transmits demand information to the optimal-policy design module; the optimal-policy design module provides policy design results to the policy execution module; the policy execution module feeds back execution results to the optimal-policy design module; and, the optimal-policy design module feeds back the results to the voltage/current demand collection module. By means of real-time selection of an optimal power output policy, the present invention solves the safety, timeliness, and versatility issues concerning demand for power, voltage, and current during the charging process.
US09969288B2 Power control system, power control method, power control device and power control program
A power control system, a power control method, a power control device and a power control program supplies power to an electric device and charge an electric vehicle. A control device and method includes a receiver that receives charge information pertaining to the charging of the rechargeable battery prior to an arrival of the electric vehicle at a location where power is supplied to the electric vehicle, and a control determination unit that determines an operation start time of starting the operation of the electric device on the basis of the charge information received by the receiver. A non-transitory computer readable recording medium stores a control program that controls the charging of a rechargeable battery of an electric vehicle and controls operation of the electric device.
US09969287B2 Vehicle charging system
A vehicle charging system may include a parking area, indicia, and a wireless charging station. The indicia may be disposed on the parking area and define a plurality of vehicle parking spots. The wireless charging station may include a primary charge coil and a mechanical conveyor having the primary charge coil mounted thereon. The mechanical conveyor may be configured to move the primary charge coil across and between the parking spots defined by the indicia.
US09969285B2 Methods and apparatus for reconfigurable power exchange for multiple UAV types
A reconfigurable system capable of autonomously exchanging material from unmanned vehicles of various types and sizes. The system comprises an environmental enclosure, a landing area, a universal mechanical system to load and unload material from the unmanned vehicle, and a central processor that manages the aforementioned tasks. The landing area may comprise a one or more visible or non-visible markers/emitters capable of generating composite images to assist in landing the unmanned vehicle upon the reconfigurable, autonomous system.
US09969283B2 Battery changing system and method
A battery changing system includes a grasping assembly and an actuation assembly. The grasping assembly is configured to be disposed onboard a vehicle and to engage a battery box having one or more batteries disposed therein. The actuation assembly is configured to move the grasping assembly away from the vehicle toward the battery box. The actuation assembly also is configured to move the grasping assembly into engagement with a securing assembly of the battery box. The actuation assembly is configured to move the grasping assembly back toward the vehicle while the grasping assembly engages the securing assembly of the battery box to lift the battery box onto the vehicle.
US09969280B2 Contactless electricity supply device
A contactless electric power supply device 100 to charge a battery 28 of a vehicle includes a power transmitting circuit 101 having a power transmitting coil 12 and a charging circuit 201 having a power receiving coil 22. An electric power is transmitted from power transmitting coil 12 to power receiving coil 22 in a contactless manner. When the vehicle approaches power supply device 100, a trial power supply in which a electric power transmission through a minute electric power is carried out is executed and a power transmission efficiency from power transmitting coil 12 to power receiving coil 22 is estimated on a basis of a current flowing through power transmitting circuit 101. From this power transmission efficiency, a determination of whether power receiving coil 22 falls in a range in which battery 28 is chargeable with respect to power transmitting coil 12 is made.
US09969276B2 Plug-in vehicle with secondary DC-DC converter
A vehicle includes a traction battery, an auxiliary battery, a charger, and two DC-DC converters. A first DC-DC converter is connected between the traction battery and the auxiliary battery through a main contactor. A second DC-DC converter is connected between the charger and the auxiliary battery. The charger is configured to charge the auxiliary battery via the second DC-DC converter when the charger is receiving power. The second DC-DC converter is configured to charge the auxiliary battery when the first DC-DC converter is disconnected from the traction battery. The second DC-DC converter can charge the auxiliary battery independent of the charger charging the traction battery. The second DC-DC converter may be configured to generally maximize power conversion efficiency in a range of power outputs associated with charging the auxiliary battery.
US09969265B2 Fuel door status indicating system for pressurized fuel system
A fuel door status indicating system for a pressurized fuel system is provided. The status indicating system includes pressure sensing means configured to measure a pressure in the fuel system, a controller operatively connected to the pressure sensing means and configured to compare a measured fuel-system pressure with a predetermined pressure, and a display operatively connected to the controller and configured to provide an indication as to whether the fuel door may be opened. The controller is configured to control operation of the display to provide the indication responsive to the comparison of the measured pressure with the predetermined pressure.
US09969259B2 Side-by-side vehicle
A vehicle may include a CVT unit or a power source which requires ambient air. An air inlet for an air intake system coupled to the CVT unit or the power source which requires ambient air may be provided in a side of a cargo carrying portion of the vehicle. The vehicle may include a rear radius arm suspension.
US09969258B1 Transaxle for zero-turn vehicle
A zero turn vehicle having an operator platform at the rear and a compact transmission design featuring a pair of transmissions disposed in a common housing and separate gear boxes permits a smaller, more efficient arrangement for the vehicle.
US09969254B2 Multi-state powertrain system including a single torque machine
A powertrain system is described, and includes an internal combustion engine having a crank member, a torque machine having a rotatable shaft member, and a transmission having an input member and an output member. The crank member of the internal combustion engine is couplable to the input member of the transmission. The rotatable shaft member of the torque machine is couplable to the crank member of the internal combustion engine at a first gear ratio. The rotatable shaft member of the torque machine is couplable to the input member of the transmission at a second gear ratio. The first gear ratio is less than the second gear ratio.
US09969252B2 Electric drive device for driving a motor vehicle
The present invention relates to an electrical drive arrangement for driving a motor vehicle comprising an electric motor, a drive shaft driven by means of the electric motor, a housing in which the electric motor is accommodated, which housing has an envelope surface and a substantially annular cross section wherein the horizontal direction of the envelope surface of said housing and hereby said drive shaft are arranged to run substantially transverse to the longitudinal direction of said vehicle, comprising a pendulum suspension for suspension of the electrical drive arrangement, where the pendulum suspension comprises a fastening configuration fixedly connected to the vehicle and at least one pendulum attachment fixedly connected to the envelope surface of the housing and pivotally journaled relative to said fastening configuration by means of a bearing configuration. The invention also relates to a motor vehicle.
US09969250B2 Sealing member of door for car
When an insertion groove, into which various parts are inserted, is formed on a sealing member, the present disclosure may maintain a width of an opening of the insertion groove greater than or equal to a predetermined width, facilitating the insertion. A sealing member 30 includes an insertion groove S into which a trim strip 45 is inserted. The insertion groove S has a side face S1 provided with a protruding portion 41c. The protruding portion 41c protrudes toward another side face S2 and abuts on the other side face S2 to set an opening width of the insertion groove S to a predetermined opening width or wider.
US09969246B2 Open roof construction for a vehicle
An open roof construction for a vehicle having an opening in the fixed roof includes an operating mechanism for a closure element and comprises a driving slide, slidably guided in the guide rail, a front support attached to the closure element, a support lever having a front end and a rear end and which is slidably connected to a panel track of the closure element by a rear sliding member. The support lever is in engagement with said rear guide track by a middle sliding member. The driving slide is configured to drive the support lever at least along part of path of movement of the closure element. The support lever is constructed such that, in an open position of the closure element, the rear sliding member at the rear end of the support lever extends above the fixed roof behind the roof opening.
US09969245B2 Sliding support arrangement and roof assembly for a vehicle
A sliding support arrangement for supporting a slidable element in a closure of a roof assembly for a vehicle with respect to mutually orthogonal X, Y and Z directions, comprising at least a guide rail extending substantially in the X-direction. The slidable element carries a slide shoe engaging the guide rail and supporting the slidable element at least in the Z-direction. The slide shoe includes a first part fixed to the slidable element and a relatively movable second part. The second part is supported by the first part mainly through a spring urging the slide shoe parts in engagement with walls of the guide rail. The spring exerts a force which is directed at a non-perpendicular angle to at least one wall of the guide rail.
US09969238B2 Hollow stabilizer
A hollow stabilizer (1) according to the invention is formed in a hollow shape and includes a bent portion (1c1, 1c2, m1-m5). With a thickness of an inner side of the bent portion (1c1, 1c2, m1-m5) being larger than a thickness of an outer side of the bent portion (1c1, 1c2, m1-m5), a hardness of the outer side of the bent portion (1c1, 1c2, m1-m5) is higher than a hardness of the inner side of the bent portion (1c1, 1c2, m1-m5) through quenching by cooling down after heating by electrical heating.
US09969233B2 Mechanical actuator with a hydraulic damper device
The invention relates to an actuator comprising a cylinder (1) in which a rod (2) is mounted to slide, the actuator having a screw (8) extending inside the rod to co-operate with a nut (7) secured to the rod, the screw being driven in rotation by a motor (10), the actuator being characterized in that a hydraulic chamber (CH) filled with hydraulic fluid is arranged inside the actuator by means of a floating piston (20) sliding in sealed manner against the rod inside of the actuator, the hydraulic chamber being in fluid flow communication with an accumulator (21) via a solenoid valve (22) that is controllable between a closed state in which the chamber is isolated from the accumulator, and a fluid-passing state in which the hydraulic chamber and the accumulator are in communication, calibrated resistance being exerted against the passage of fluid from the chamber towards the accumulator.
US09969227B1 Amphibious utility wagon
Method and apparatus for a floatable and collapsible cart having a storage compartment formed by a framed assembly with waterproof material mounted thereon. Floatation material is disposed in the bottom of the storage compartment and front and rear ground contacting wheels are provided below and in line with the opposite sides of the storage compartment which may be converted between a folded position and an unfolded position. Objects may be loaded into the storage compartment and pulled by a user on the surface of the water between a boat and the seashore and then rolled along the seashore. A pull cord is provided for pulling the wagon.
US09969224B2 Pneumatic vehicle tire
A vehicle tire has outer shoulders and two tread halves. The tire includes a tread having six block rows and a plurality of circumferential grooves. Mutually adjacent ones of the block rows are separated from each other by a corresponding one of the plurality of circumferential grooves. Each of the block rows has individual blocks separated from each other by mutually parallel essentially straight transverse grooves running at an angle to the axial direction of the tire. The circumferential grooves include first circumferential grooves having a maximum profile depth and second circumferential grooves having a second profile depth less than the maximum profile depth. The transverse grooves have a depth approximately corresponding to a maximum profile depth at first outlet locations. The transverse grooves have a depth corresponding to the second profile depth at second outlet locations.
US09969223B2 Pneumatic tire
A pneumatic tire includes a tread portion including a first tread pattern and a second tread pattern. The first tread pattern and the second pattern are formed as substantially symmetrical design to the tire equator and arranged such that pattern phases thereof are shifted one another in a circumferential direction of the tire. Each of the first tread pattern and the second tread pattern is provided with lateral inclined grooves each extending axially inwardly with an inclination from a tread edge to an axially inner end located near the tire equator, an inner connecting groove connecting between a pair of circumferentially adjacent lateral inclined grooves, and an outer connecting groove connecting between a pair of circumferentially adjacent lateral inclined grooves. A central connecting grooves is arranged to connect between a pair of axially adjacent lateral inclined grooves.
US09969218B2 Wheel and tire assembly
A wheel assembly comprising a rigid wheel including a radially outer rim wall presenting a polygonal shape with a plurality of outermost vertices connecting a plurality of planar faces, and a flexible tire mounted on the outer rim wall. The tire is supported by the vertices of the rim wall and is separated from the rim faces by a space, portions of the tire located between the vertices being configured to flex inwardly when subject to ground engaging pressure.
US09969217B2 Laminated body and pneumatic tyre using same
A laminate comprising at least one layer of a first thermoplastic resin composition alternately stacked with at least two layers of a second thermoplastic resin composition so that the outermost layers are the layers of the second thermoplastic resin composition, wherein the first thermoplastic resin composition comprises at least one selected from the group consisting of ethylene-vinyl alcohol copolymer and modified ethylene-vinyl alcohol copolymers, and the second thermoplastic resin composition has a different composition from the first thermoplastic resin composition, and wherein, in any adjacent pair of the layer of the first thermoplastic resin composition and the layer of the second thermoplastic resin composition, the layer of the first thermoplastic resin composition and the layer of the second thermoplastic resin composition have a specific tensile modulus ratio and a specific thickness ratio.
US09969206B2 Marker storage accessory
A marker storage accessory includes a main body having marker-engaging structure and writing surface engaging structure. The main body may also include cap-engaging structure or, alternatively, blocking structure. The marker-engaging structure includes a plurality of circumferentially positioned teeth adapted to be conformingly inserted into the complementarily shaped channels defined by the ribs located on the non-writing end of a writing instrument such as a dry-erase marker. The cap-engaging structure can include ribs creating a geometry adapted to conformingly receive the protruding end of a cap for the writing instrument. The blocking structure can be a protrusion adapted to prevent attachment of the marker storage accessory on the nub-end of the writing instrument while permitting attachment of a marker cap. When the marker storage accessory is attached to the writing surface, the marker self-positions to a generally nub-down orientation.
US09969204B2 Clipboard device with elastic retainer
A clipboard device having an elastic retainer member which is alternately deployable to hold papers or other items in place on the front or rear surface of the clipboard and related methods of manufacture and use.
US09969199B2 Process for creating sub-surface marking on plastic parts
Techniques or processes for providing markings on products are disclosed. In one embodiment, the products have housings and the markings are to be provided on sub-surfaces of the housings. For example, a housing for a particular product can include an outer housing surface and the markings can be provided on a sub-surface of the outer housing surface yet still be visible from the outside of the housing. Since the markings are beneath the surface of the housing, the markings are durable.
US09969197B2 Inkjet recording apparatus with cover and method therefor including decision and inquiry features
An inkjet recording apparatus includes an ink tank forming an ink chamber and including an injection inlet, a cover, a cover sensor, a recording head, a monitor, and a controller. The cover is movable between a covering position and an exposing position. The cover sensor is positioned to output a signal depending on the position of the cover. The controller controls operation of the recording head, the monitor. The controller receives either a first positional signal or a second positional signal of the cover sensor, and based on receipt of the first positional signal after receipt of the second positional signal from the cover sensor, performs a decision process deciding whether an operation regarding ink injection into the ink chamber is completed.
US09969191B2 Label die cutting machine, printing device, and label die cutting method
A label die cutting device enables easily changing the shape of the die cut made in label paper. A printer 1 has a print unit 7 and a die cutting process unit 8 (label die cutting device). The die cutting process unit 8 has a conveyance path 9 for conveying the label paper 5, a die cutting unit including wire pins 41 and a wire pin drive mechanism 42 for advancing and retracting the wire pins 41, and a die cutting controller 68 for driving the wire pin drive mechanism 42 to strike the wire pins 41 against the label paper 5 on the conveyance path 9 and die cut the label paper 5 based on print data. The die cutting unit is a wire dot head 27.
US09969189B2 Printer
There is provided a printer including, in a sheet holding section configured to hold roll paper formed by rolling a printing target sheet, a pair of pressing sections configured to hold the roll paper from both side ends, and a holding section provided in each of the pressing section. The holding section is displaceable to a first position where the holding section projects to a side opposed to a side end portion of the roll paper and a second position where the holding section does not project. The holding section enters a cylindrical portion in a rolling center of the roll paper in the first position to hold the roll paper.
US09969186B1 Inkjet printer
A printer includes an ink head, a first heater, a second heater, and a controller. The ink head includes first and second ink heads arrayed along a main scanning direction. The first heater is upstream of the platen in a sub-scanning direction, and heats the recording medium. The second heater is below the platen, and heats the recording medium placed on the platen. The controller includes a heater controller that controls the first and second heaters so that the surface temperature of a first region in which a first ink ejected from a first upstream nozzle array lands becomes higher than the surface temperature of a second region in which a second ink ejected from the second downstream nozzle array lands.
US09969184B2 Droplet ejection device
A droplet ejection device includes: a droplet ejection head that ejects a droplet to a recording medium; an irradiating portion that evaporates moisture of the droplet landed on the recording medium by irradiating the recording medium with infrared laser beam; and a light shielding member that includes an upper light shielding member provided on a perimeter of the irradiating portion and a lower light shielding member provided on a position facing the irradiating portion and the upper light shielding portion while placing the recording medium therebetween, in which the upper light shielding portion and the lower light shielding portion are in contact with each other at an outside of the recording medium in the width direction so that the light shielding member shields the infrared laser beam at least in the width direction of the recording medium.
US09969182B2 Image recording method, and treatment liquid and liquid set used therein
An image recording method including the steps of forming an image by applying an ink to an ink receiving member and applying a treatment liquid containing an ink-viscosity-increasing component to the ink receiving medium so as to overlap with at least a part of a region of the ink receiving medium to which the ink is applied. The treatment liquid contains a surfactant which lowers a surface tension of water to 25 mN/m or less when added into the water in an amount of 0.1% by mass; and an additive containing at least one compound selected from the group consisting of compounds represented by general formulae (1) to (4):
US09969175B2 Liquid container
Provided is a liquid container that is able to prevent or suppress spilling of a liquid that is poured into an opening part. An ink cartridge has a first wall part defining a rear end of the ink cartridge and a second wall part extending on a forward side +X from an upper edge of the first wall part. An ink inlet port that receives ink for refilling is formed in the second wall part. Ink is poured into the ink inlet port from the first wall part side. The ink inlet port has a length dimension in the front-rear direction X that is longer than in the width direction Y, and thus readily receives ink that is poured therein.
US09969170B2 Print device having maintenance mechanism for head unit
A print device includes a head, a cap, a suction portion, an absorption member, and a plate-shaped member. The head has an ejection surface. The ejection surface has a plurality of nozzles formed in the ejection surface and is directed in a predetermined direction. The cap has a frame-shaped wall portion and a suction opening. The suction portion is connected to the inside of the cap via the suction opening. The absorption member is arranged in a position surrounded by the frame-shaped wall portion and is configured to absorb liquid. The plate-shaped member is arranged in a position surrounded by the frame-shaped wall portion and is extending along an inner end surface of the frame-shaped wall portion.
US09969166B2 Inkjet head with a plurality of integrated nozzles
An inkjet head comprises a pressure chamber; a nozzle plate including a first surface at the side of the pressure chamber, a second surface opposite to the first surface, a first nozzle formed into a frustum which penetrates the first surface and the second surface and the diameter of which decreases as it goes closer to the second surface, and a second nozzle formed into a frustum which is the same as the frustum of the first nozzle; and a driving element configured adjacent to the pressure chamber to eject droplets from the first nozzle and the second nozzle simultaneously; wherein the part of the first nozzle on the first surface is integrally connected to the part of the second nozzle on the first surface, and the part of the first nozzle on the second surface is separated from the part of the second nozzle on the second surface.
US09969165B2 Liquid discharge head and liquid discharge apparatus
Multiple recording elements are disposed on one face of a recording element board, and a groove-shaped liquid supply channel is provided on the other face in common for the recording elements. Multiple supply ports passing through the recording element board and communicating the liquid supply channel with pressure chambers, and supply-side openings serving as supply ports of liquid to the liquid supply channel are further provided. When discharging liquid, the sum of pressure drop of the liquid from any supply-side opening to the supply port at a position farthest removed from that supply-side opening, and the pressure drop of the liquid at the supply port, is 5000 Pa or less.
US09969163B2 Liquid discharge head
A liquid discharge head includes a discharge unit that discharges a liquid as a result of electric energy being supplied to the discharge unit, a first wiring member that is joined to the discharge unit and that includes a plurality of first joining terminals each capable of transmitting the electric energy to the discharge unit, and a second wiring member that is electrically joined to the first wiring member and that includes a plurality of second joining terminals. At least three of the plurality of first joining terminals are inspection terminals that are short-circuited, and the second joining terminals are connected to contact terminals to each of which an external signal can be input.
US09969158B2 Electrospray emitter and method of manufacture
An electrospray emitter (10) for emitting a liquid comprising a sheet (40) having a channel (65) opening to an aperture (55) on a flat emitter surface extending across the sheet (40). A charging electrode (80) coupleable to an electrical supply and arranged to apply an electrical charge to liquid passing into the channel (65). A control electrode (50) proximal to the channel (65) for controlling electrospray emission, that may be embedded in the sheet. A non-wetting or insulating layer (30) may be applied to the sheet.
US09969156B2 Transverse sheet withdrawal brake
A method for operating a device that applies a force to a print sheet during a folding operation, wherein the print sheet is in a specified starting position prior to the folding operation. Braking-force triggering pulses are directed toward the print sheet to counter the acceleration of the print sheet in the starting phase of the folding operation and/or to counter fluttering movements that occur during the intake of the print sheet. The pulses exert an intermittent, uniform or oscillating force onto at least a section of the print sheet. The pulses are controlled by a control unit which operates based on control profiles resulting from queried operating parameters and/or based on stored control profiles.
US09969151B2 High sound absorption coefficient expanded PTFE composite fiber cotton
The present invention discloses a high sound absorption coefficient expanded PTFE composite fiber cotton, comprising a melt-blown high polymer fibrous layer and an expanded PTFE film layers or a modified film layer of expanded PTFE, the modified film layer of expanded PTFE is made by conducting modification treatment to a PTFE film; the high sound absorption efficiency expanded PTFE composite fiber cotton is made by combining the melt-blown high polymer fibrous layer and the expanded PTFE film layer or the modified film layer of expanded PTFE. Thus, the present invention with better full-frequency sound absorption capability and marked full-frequency sound absorption effect can be bound in a large area or filled on automobiles' engine hoods, body racks or the inner side face of automobile trunks to substantially absorb automobile noise; it has advantages such as chemical inertness, waterproof, dustproof, permeable filterability, long service life and weldability.
US09969145B2 Vehicle-windshield-glass intermediate film, rolled body, and vehicle windshield glass
The present invention aims to provide an interlayer film for an automotive windshield which, while having recesses in the shape of engraved lines, enables the production of automotive windshields with high yield by a vacuum deaeration method; a roll of the interlayer film for an automotive windshield; and an automotive windshield including the interlayer film for an automotive windshield. The present invention relates to an interlayer film for an automotive windshield. The interlayer film includes, on at least one surface thereof, a large number of recesses and a large number of projections. The recesses have a groove shape with a continuous bottom. The recesses are adjacently arranged regularly side by side in parallel with one another. The recesses in a groove shape with a continuous bottom are inclined 35° or more relative to the machine direction of the film in production of the interlayer film for an automotive windshield.
US09969138B2 Mold for a tire having a shell with removable parts
A mold for vulcanizing and molding a tire is disclosed herein. The tire includes a tread delimited by two sidewalls, and the mold includes a ring for molding the tread of the tire and two shells having tire-molding surface features for molding the sidewalls. At least one of the shells has a removable shell part extending circumferentially on the side of the sidewall of the tire to be molded, with the tire-molding surface features being incorporated into the removable shell part.
US09969136B2 Inflatable pouches
A supply of inflatable pouches includes an inflatable web defining a series of inflatable chambers, a longitudinal fold in the web such that the web is configured in the form of two juxtaposed inflatable panels joined together at the longitudinal fold, and a series of transverse seals that bond the panels together to form a series of inflatable pouches between pairs of the transverse seals.
US09969133B2 Rail apparatus for wind turbine blade construction
An apparatus for positioning sheets of material in a wind turbine blade mold to form a shell of a wind turbine blade, the mold having a mold surface defining the profile of a portion of the shell, the apparatus comprising: a rail that, in use, is mounted proximate to the mold and follows a path in a direction along the longitudinal length of the mold; and a sheet mounting apparatus coupled to the rail, the mounting apparatus configured to releasably hold a sheet of material and to move along the rail.
US09969132B2 System for forming stacks of composite materials
The system for forming stacks of composite materials comprises a form (1) which defines the section that is desired to provide to a stack (2) of composite material placed thereon to obtain a formed stack (2′); a counter-form (3), which together with the form (1), forms and obtains the formed stack (2′); and it is characterized in that the system also comprises transition elements (4) deformable, that adopt a variable section from an initial section in one of its ends and the end section defined by the form (1) in the other end.It allows changing the geometry during the forming of the laminate, to obtain laminates of variable section along its length. For this purpose, the form and counter-form must have a variable geometry at will.
US09969130B1 Nozzle cleaning module
A nozzle cleaning module including a base housing, a main carrier, a sub-carrier, a driving assembly and an interference structure is provided. The main carrier is received in the base housing, a wiper protrudes upwardly from the main carrier, and the main carrier has a sub-slope. The sub-carrier is received in the main carrier, a cover protrudes upwardly from the sub-carrier, and at least a portion of the sub-carrier is in contact with the sub-slope. The driving assembly is connected to the main carrier and obliquely lifts the main carrier in relation to the base housing to lift the wiper. The sub-carrier moves along with the main carrier at the same time. The interference structure is arranged corresponding to the sub-carrier to move the sub-carrier along the sub-slope, so the cover can be raised.
US09969126B2 Assembly sticking devices
An assembly sticking device includes an absorbing device for absorbing a plurality of optical sheets, and a transmission device arranged below the absorbing device for horizontally transporting the curved backlight module to be assembled with the optical sheets. When the transmission device horizontally transmits one of the curved backlight modules to be right below the absorbing device, the absorbing device configures one optical sheet to face toward the curved backlight module, the absorbing device moves close to the transmission device, and releases the optical sheets such that the released optical sheets is assembled with the curved backlight module.
US09969120B2 Adjustable-angle pressing or nip roll
An improved adjustable-angle pressing or nip roll is distinguished, inter alia, by the following features: the angle adjusting device comprises a double-armed lever, the moving device is constructed in such a way that, via this, a pivot axis of the double-armed lever can be adjusted relative to the process roll, and the angle adjusting device comprises, for the double-armed lever, a stop which acts at least on one side, in such a way that, in the case of further force loading by the force actuating unit, a pressing force can be generated which acts on the pivot axis of the double-armed lever and via which the pressing or nip roll can be pressure-loaded onto the roll shell of the process roll with the material web being guided through between the two rolls.
US09969117B2 Transport device and method for transporting plastic containers or preforms
Disclosed are a device for reshaping preforms to plastic containers (2), a transport device (1), as well as a method for transporting plastic containers (2) or preforms. The device (100) for reshaping preforms into plastic containers (2) comprises at least two blow moulds (81) in which the preforms are expanded into plastic containers, arranged on a circumferentially driven blowing wheel (80), a heater (50) for heating the preforms, and a transport device (1) for the plastic containers (2) or preforms. The transport device (1) comprises a motor drive (5) having a drive shaft (15) that drives a support (17) with at least two gripping and/or support elements (4) for the respective plastic containers (2) or preforms to be transported in a rotary fashion, wherein the gripping and/or support elements (4) are mounted with a linear bearing (21) so as to be movable relative to the support, wherein the linear bearing has at least one rail, which is surrounded at least in sections by a cage (71), and that a plurality of rollers (72), in particular more than 50 rollers, which roll on the rail (73), is arranged in the cage (71).
US09969114B2 Device for producing plastic tubes
An apparatus produces plastic tubes by extrusion with an extruder, a pipehead being attached to the extruder in production direction, having a base material with at least one mandrel and a sleeve, a melt channel between the mandrel and the sleeve, the melt channel shaped to aid flow in production direction at least at the mandrel's end and at the sleeve's end, the mandrel and sleeve being adjustable backwards and forward relatively to one another, the outer surface of the mandrel and/or the inner surface of the sleeve at least partially has a material that allows for a higher sliding quality than the base material. The outer and/or the inner surface (i) has a coating either unvaried, or whose sliding quality constantly improves, or whose sliding quality alternately improves and worsens, in the production direction, or (ii) is partially coated, or (iii) the mandrel and/or sleeve fronts are coated.
US09969113B2 Wireless sensor for electromagnetically shielded applications and method of communication
A wireless sensor system is described which can be used to measure temperature and/or pressure within an electromagnetically shielded environment. The sensor system includes an embedded processor which intermittently transmits data from the sensors. In electromagnetically shielded environments, the processor transmits the data when the electromagnetically shielding components are moved into a non-shielding configuration.
US09969104B2 Automatic control of assemblies of a water supply system
A method for controlling a water supply system for use with a machine tool is disclosed. The water supply system includes a housing with an interface for supplying electrical energy, a water tank, a line, a pump device, a current-measuring device, a water-pressure-measuring device, and a control device. The method includes activating the pump device if the machine tool is connected to the interface and the motor current of the machine tool exceeds a predetermined threshold value, and deactivating the pump device if the machine tool is connected and the motor current undershoots a predetermined threshold value; or activating the pump device if the machine tool is not connected and the water pressure in the line undershoots a predetermined threshold value and deactivating the pump device if the machine tool is not connected and the water pressure exceeds a predetermined threshold value.
US09969103B2 Environmental-friendly mortar mixing robot
An environmental-friendly mortar robot comprises a first, second, third, and fourth container module. The first container module (2) consists of a sand midway silo, a weighing system, a stirring system, and a control system; the second container module (3) consists of a cement silo, a spiral conveying machine, a material level meter and a water storage tank; the third container module (4) consists of a fly-ash silo, a spiral conveying machine, a material level meter and an air storage tank with an air compressor; the fourth container module (5) consists of a sand storage bin, an elevator, a material level meter and an additive storage box. While transporting, the first container module can be respectively detached into four functional modules which are directly put onto a transporting vehicle together with other three container modules for transportation.
US09969102B2 Composition and method for obtaining exposed aggregates in surfaces of moulded concrete and other cementitious materials
Surface retarder coating compositions of the invention are based on the use of at least one non-Ordinary Portland Cement (non-OPC) binder and at least one OPC set retarder agent, which are provided in powder form that can be mixed with water at the construction site. The coating is applied onto the surface of a mould or formwork using roller or spray equipment, and concrete can then be cast within 30-60 minutes against the coating. The OPC set-retarding agent operates to retard setting of the concrete so that it can be de-moulded the next day and its surface can be removed using a high pressure water spray to reveal aggregate embedded beneath the removed surface.
US09969091B2 Safety utility blades, assemblies and methods of manufacturing
The present disclosure relates to safety blades for use in utility knives, related assemblies and methods of manufacturing. More specifically, the present disclosure relates to safety blades for use in utility knives, related assemblies and methods of manufacture which limit user exposure to associated cutting edges.
US09969076B2 Connection device for hexagonal wrench
A connection device for a hexagonal wrench and includes a first part and a second part. The first part has an insertion section through which multiple hexagonal first recesses are defined, and an operation portion formed on one end thereof. The operation portion has multiple second hexagonal second recesses. The second part has a reception hole in which the insertion section is inserted and is positioned relative to the second part. The second part has an opening and the first recesses are exposed. The second part has another operation portion on one end thereof. The operation portion has multiple third hexagonal recesses. The first, second and third hexagonal recesses have different sizes and are Metric system and English system.
US09969064B2 Ratchet tool with stacked switching device
A ratchet tool with stacked switching device includes a handle, two stacked engaging assemblies, two springs, a toothed wheel, and a control unit. Each of the engaging assemblies includes stacked first and second engaging members. The engaging portions of the first and second engaging members are staggered. Since the toothed wheel selectively engages with the engaging portions of the first and second engaging members, the number of teeth of the toothed wheel to be engaged with the two engaging assemblies is the sum of the number of teeth of the engaging portions of the first and second engaging members, thus enhancing the fineness of the rotation of the toothed wheel, and improving the easiness and applicability of the ratchet tool, without impacting the structural strength.
US09969062B2 Wrench for operating objects of different sizes
A wrench includes a first part, a second part and a third part. The first part has a first toothed portion and a first pivotal portion. The second part has a third pivotal portion which is connected to the first pivotal portion so that the second part is pivoted an angle relative to the first part about the first pivotal portion. The third part is movably connected to the second part and has a second toothed portion which faces the first toothed portion so that objects of different sizes are clamped between the first and second toothed portions.
US09969059B2 Sandpaper with laminated non-slip layer
A sheet of sandpaper includes a backing layer having opposed first and second major sides, an adhesive make coat on the second major side, abrasive particles at least partially embedded in the make coat, thereby defining an abrasive surface, and an exposed laminated non-slip layer on the first major side. Methods of making and using such sandpaper are also provided.
US09969051B2 Holder for pneumatically blocking an optical lens
A holder (1) for pneumatically blocking an optical lens (300) on a surfacing machine, includes:—a gripping part (10) for fixing it to a corresponding member (200) of the surfacing machine, and—a part (100) for blocking the optical lens, which includes a body (110) from which there protrude abutments which are designed to afford the optical lens a rigid seat, and a seal (170) against which the optical lens is able to be brought to bear in order to delimit with the body a vacuum chamber (180). The abutments include first rods (160) which are mounted so as to be movable in translation with respect to the body in order to bear by way of their free ends (161) against the optical lens, and provision is made of return elements (179, 190) for returning the first rods against the optical lens.
US09969045B2 Method and device for dispensing solid compound pastes for surface processing, and related surface processing method and system
A method for dispensing solid compound pastes for surface treatment to a machining tool comprises the steps of providing a solid compound paste for surface treatment that contains abrasives, softening at least a partial amount of the solid compound paste by supplying thermal energy, feeding the softened solid compound paste to a dosing device by means of a conveyor device that is adapted for abrasive media, and applying the softened solid compound paste to a machining tool by means of the dosing device. A device for dispensing solid compound pastes for surface treatment to a machining tool comprises a heating device that is arranged to heat a solid compound paste for surface treatment that contains abrasives, wherein at least a partial amount of the solid compound paste is arranged to be softened by supplying thermal energy, a conveyor device having a pump unit comprising at least one pump and at least one conveyor path for the softened solid compound paste, wherein the pump is arranged for conveying abrasive media, and a dosing device arranged for applying the softened solid compound paste to a machining tool.
US09969043B2 Drilling apparatus and methods of using same
A drilling apparatus comprising: at least one bit; a vacuum shroud, including a compressible boot, disposed around a longitudinal axis of the apparatus and configured to be in operative communication with a vacuum attachment port; and at least one magnetic element disposed near a distal end of the apparatus and configured to attract metallic debris resulting from drilling apparatus operation.
US09969037B2 Dual-spindle machining apparatus
An apparatus for machining a workpiece has a housing having a vertical front wall and first and second side walls extending generally perpendicularly back from outer edges of the front wall, directed horizontally oppositely away from each other, and defining first and second planes themselves delimiting a space. First and second vertical guides on the first and second side walls outside the housing carry first and second vertical slides moveable vertically on the first and second vertical guides of the first and second side walls. First and second horizontal guides on the first and second vertical slides carry first and second horizontal slides movable horizontally on the first and second horizontal guides of the first and second vertical slides between the first and second front work stations and the first and second rear transfer stations.
US09969036B2 Fireproof flexible hoses with polyimide inner structures
Provided are fireproof flexible hoses, aircraft having fire suppression systems including such fireproof flexible hoses, and methods of forming such fireproof flexible hoses. A fireproof flexible hose includes an inner structure and an outer structure at least partially enclosing and directly interfacing the inner structure. The inner structure forms an inner surface of the fireproof flexible hose and includes a polyimide at least at the inner surface. The polyimide has good fireproofing and temperature resistant characteristics and, unlike other polymers, does not need to be thermally isolated when the hose is exposed to fire. The outer structure may be made from metal and/or non-metal and may provide mechanical support to the inner structure. The outer structure may have a convoluted shape to ensure flexibility of the overall hose assembly. In some examples, a set of gaps may be present between the outer and inner structures for additional flexibility.
US09969026B2 Weld schedule for resistance spot welding of aluminum alloy workpieces
Aluminum-base alloy workpieces have surfaces with films of aluminum oxide which inhibit good contact with weld faces of resistance spot weld electrodes and the faying surfaces of, for example, sheet workpieces stacked for welding. Sometimes, the surfaces of the sheets also are coated with an adhesive or a sealer which further complicates welding. But in accordance with this invention, weld faces of opposing, round, copper welding electrodes are pressed against opposite outside surfaces of the sheets at a spot weld site and weld current is applied to the electrodes in accordance with a three-stage weld schedule to better form each weld. The weld schedule comprises a Conditioning stage (stage 1), a weld nugget Shaping stage (stage 2), and a weld nugget Sizing stage (stage 3).
US09969019B2 Method for the gear manufacturing machining of a workpiece by a diagonal generating method
A method for the production of a workpiece having a corrected gear tooth geometry and/or a modified surface structure by a diagonal generating method by a modified tool, wherein a modification of the surface geometry of the tool is produced in that the position of the tool dresser is varied during dressing in dependence on the angle of rotation of the tool and/or on the tool width position and/or wherein a modification of the surface geometry is produced which has a constant value at least locally in the generating pattern in a first direction of the tool and is given by a function in a second direction of the tool which extends perpendicular to the first direction, wherein the modification of the tool produces a corresponding modification on the surface of the workpiece, and wherein the modification on the surface of the workpiece is a directed crowning without shape deviations.
US09969013B2 Table saw with actuator module
A power tool in one embodiment includes a swing arm assembly movable along a swing path between a first swing arm position and a second swing arm position, a latch pin pivotable between a first position and a second position, an actuator module configured to receive a plurality of actuators, a first actuating module position within the actuator module configured to align a first of the plurality of actuators with a strike plate on the swing arm assembly, a loader configured to bias a second of the plurality of actuators from a second actuating module position within the actuator module toward the first actuating module position, and a control system configured to actuate each of the plurality of actuators positioned in the first actuating module position to force the swing arm assembly away from the first swing arm position and toward the second swing arm position.
US09969010B2 Hole saw drill guide
A hole saw drill guide is described. The drill guide can be used when drilling holes in pipe or tubes. The hole saw drill guide includes a guide tube base assembly and an arbor shaft assembly. The guide tube base assembly is chained or otherwise secured to a pipe. The arbor shaft assembly is removably engaged with the guide tube base assembly and during use of the device, rotates within a guide tube of the base.
US09969008B2 Device for holding mechanical parts
This invention relates to a maintaining device for mechanical pieces, comprising a slider-holder formed by a body and a head with a central bore in which a part of the piece to be maintained is placed, the piece to be maintained exceeding the head, the head comprising a conical area, the maintaining device having at least two sliders and an actuation element for the sliders, wherein the head comprises at least two lateral bores, one leading into the conical area and the other to the central bore, the sliders are placed in the lateral bores, the sliders being adjustable in the lateral bores, the sliders exceeding the conical area of the head, the actuation element of the sliders being arranged to move the sliders in the corresponding lateral bores along an axis perpendicular to a longitudinal axis of the central bore.
US09969007B2 Coated cutting tool
A coated cutting tool includes a substrate and a coating having at least one α-type aluminum oxide layer. In a cross-section of the α-type aluminum oxide layer, when an angle formed by a normal to the cross-sectional surface and a normal to a (222) plane of a particle of the α-type aluminum oxide layer is regarded as a misorientation, and when areas of particles, each of which has a misorientation ranging from 0-90 degrees, of the α-type aluminum oxide layer are defined as constituting 100 area %, and the areas of particles, each of which has a misorientation ranging from 0-90 degrees, of the α-type aluminum oxide layer are divided into respective 10-degree pitches, a total Sa of the areas of particles having a misorientation ranging from 20-30 degrees, of the α-type aluminum oxide layer is at a maximum from among totals of areas for nine divisions in respective 10-degree pitches.
US09969004B2 α+β or β titanium alloy and method for producing same
Titanium alloy containing iron, that is, iron-containing titanium alloy having high strength and hardness in which iron in a composition which cannot be realized in a conventional method, is contained with no segregation, and is provided in lower cost. The α+β titanium alloy or β titanium alloy is produced by a forming process such as hot extrusion of titanium alloy powder containing 3 to 15 mass % of iron powder. The method for production of the α+β titanium alloy or β titanium alloy includes a step of mixing 3 to 15 mass % of iron powder and titanium alloy powder as the remainder, and a step of performing a forming process of hot extrusion on this powder mixture.
US09969003B2 Process for manufacturing a porous body by powder metallurgy and metallurgic composition of particulate materials
The process comprises the steps of: mixing a load of oxide ceramic material particles (10) with a load of space holder particles (20), defined by graphite and/or amorphous carbon; compacting the mixture formed by ceramic material particles (10) and space holder particles (20), to form a compact body (E); and sintering said compact body (E), so that the ceramic material particles (10) form sintering contacts with each other, whereas the carbon of the space holder particles (20) is removed by the reaction with the oxygen in the sintering medium, to form open secondary pores (II), by eliminating the space holder particles (20). The metallurgic composition comprises the mixture of the ceramic material particles (10) with the space holder particles (20).
US09969001B2 Three-dimensional passive components
Three-dimensional inductors may comprise a passivation layer disposed on a substrate, a three-dimensional pillar comprising a ferromagnetic material disposed on the substrate or the passivation layer, and a conductive trace wound at least partially around the pillar. Three-dimensional capacitors may comprise a passivation layer disposed on a substrate, at least two support pillars comprising a polymeric material disposed on the passivation layer or the substrate, at least two electrodes disposed between the support pillars, a dielectric disposed between the electrodes, and a metal trace. Methods of manufacturing the three-dimensional passives, such as inductors and capacitors, may comprise direct writing the components and curing them for on-chip applications.
US09969000B2 Additive manufacturing of joining preforms
A method of fabricating a joining preform includes the step of printing a self-fluxing joining alloy. Joining includes brazing and soldering. The self-fluxing joining alloy contains at least one of phosphorus, boron, fluorine, chlorine, or potassium. Another printing step prints a non-phosphorous joining alloy. Both printing steps are performed by an additive manufacturing or 3D printing process. The printing a self-fluxing joining alloy step may be repeated until the non-phosphorous joining alloy is substantially encapsulated by the self-fluxing joining alloy. The self-fluxing joining alloy may be a BCuP alloy, a CuP alloy, a CuSnP alloy, a CuSnNiP alloy or a CuAgP alloy. The non-phosphorous joining alloy may be a BAg alloy, a BNi alloy or a BAu alloy.
US09968993B2 Feeder system
The present invention relates to a feeder system for metal casting. The feeder system comprises a feeder sleeve mounted on a tubular body. The feeder sleeve has a longitudinal axis and comprises a continuous sidewall that defines a cavity for receiving liquid metal during casting. The sidewall extends generally around the longitudinal axis and has a base adjacent the tubular body. The tubular body defines an open bore therethrough for connecting the cavity to the casting. A groove extends into the sidewall from the base to a first depth and the tubular body projects into the groove to a second depth and is held in position by retaining means. The second depth being less than the first depth so that upon application of a force in use the retaining means are overcome and the tubular body is pushed further into the groove.
US09968992B2 System and method for using cloth filters in automated vertical molding
The present invention is a multipart system and method for using cloth filters in automated vertical molding. The system includes a filter setter, a filter print plate and a filter back shelf. The filter setter removably mounts to a mechanical arm and releasably carries at least one cloth filter between upper and lower jaws. The filter print plate mounts to a ram plate while the filter back shelf mounts to a swing plate. During vertical molding, the ram plate and swing plate compress sand to create a mold. The mounted filter print plate creates at least part of a print aperture into which the filter setter inserts the cloth filter. The apertures created by the filter print plate and the filter back shelf support the cloth filter during the founding process.
US09968989B2 Lithium-containing molding material mixture based on an inorganic binder for producing molds and cores for metal casting
The invention relates to lithium-containing molding material mixtures comprising a refractory main molding material, an inorganic binder, and amorphous silicon dioxide as an additive in the production of molds and cores for metal casting. The invention further relates to a method for producing molds and cores using the molding material mixtures and to molds and cores produced according to the method.
US09968980B2 Coatings for forming tools
A hard coating comprising at least one hard layer with dedicated architectural design for attaining enhanced tribological performance (low abrasive and adhesive wear) at room and elevated temperatures in contact with Al-, Zn- and Fe-based or other counter bodies.
US09968971B1 Friction washer that cleans plastic for recycling
A method of cleaning plastic chips includes introducing a mixture of plastic chips and water to an in-feed of a housing. The mixture of plastic chips and water is impelled from the in-feed within the housing and agitated so that debris on the plastic chips is abraded by adjacent chips and agitators until substantially all debris has been removed from the plastic chips. Water and debris are discharged through a screen to a debris discharge. Cleaned plastic chips are discharged to a plastic chip discharge that is further from the in-feed than the debris discharge. Chip discharge takes place when the pressure of the plastic chips at the plastic chip discharge exceeds a threshold.
US09968970B2 Spin chuck with in situ cleaning capability
In a method and apparatus for processing wafer-shaped articles, a spin chuck is positioned inside a process chamber. The spin chuck is configured to hold a wafer-shaped article at a predetermined process position. A cover covers the spin chuck and is affixed to or integral with the spin chuck for rotation therewith. The cover has a central opening. A stationary nozzle assembly extends into the process chamber such that a discharge end of the stationary nozzle assembly passes through the central opening of the cover. The nozzle assembly comprises a rinse nozzle configured to direct rinse liquid radially outwardly of the nozzle assembly onto a downwardly-facing surface of the cover.
US09968964B2 Coating method using particle alignment and particle coated substrate manufactured thereby
Disclosed is a coating method using particle alignment, including preparing a cohesive polymer substrate having a smooth surface; and coating the smooth surface of the cohesive polymer substrate with a plurality of particles while forming recesses respectively corresponding to the particles on the smooth surface of the cohesive polymer substrate by pressing the particles to the cohesive polymer substrate, so that binding properties between the particles and the cohesive polymer substrate are enhanced.
US09968961B2 Coral dipping tank
A dipping tank includes a pump, a container, a fitting, and a plate which is used to place objects, such as corals, to be dipped. The pump draws fluid from inside the container and discharges it into the container through the fitting. The fitting includes two flexible hoses, one with a propulsive nozzle and the other with one or more dipping nozzles. The propulsive nozzle produces a jet which impinges upon the blades protruding from the bottom side of the plate causing the plate to rotate. The dipping nozzles eject jets which are used to spray and thereby dip the objects. Flexible hoses are configured so as to provide movements in 6 degrees of freedom for the nozzles. Flexible hoses may also further comprise valves to control fluid flow through said hoses.
US09968959B2 Component delivery system utilizing film bags
A dispensing apparatus includes two cylindrical sleeves, two flexible film pack bags disposed within the sleeves, the two film pack bags having an integrally formed rigid face plate bonded therewith, the face plate having a discharge nosepiece integrally formed therewith, the discharge nosepiece having a partition internally configured to maintain separate flow streams from the film pack bags. Two shuttles are slidingly disposed in the sleeves. Push rods are disposed in operable communication with the shuttles. At least one piston is disposed in operable communication with the push rods, the piston configured to drive the push rods. A holder is disposed proximate a front end of the sleeves, the holder configured to restrain the face plate during dispensing of a flowable material. A mixer is configured to be in fluid communication with flow streams from the film pack bags. A material applicator is disposed in fluid communication with the mixer.
US09968949B2 Pulsating irrigation device
A pulsating irrigation device is provided that transforms a fluid flow entering the device to an intermittent pulsating fluid flow that is ejected from the device. The device has a chamber and at least one compressible member in pressure contact with the chamber. The compressible member compresses to assist the formation of the pulses ejected from the device and the fluid within the chamber is substantially sealed from contact with the interior of the compressible member.
US09968939B2 Shredding device
Shredding device for shredding material comprising a housing: a rotor and one or more counter blades which are arranged in the housing such that they interact for shredding the material; a pusher element that is movable such that it pushes the material to be shredded in the direction towards the rotor and the counter blades; a hopper for feeding the material which is arranged movable on the housing between a first and a second position, where, in its first position, the material may be fed to the rotor and the counter blades, and in its second position, the rotor and the counter blades are freely accessible from the exterior of the shredding device.
US09968932B2 Microchannel chip for microparticle separation, microparticle separation method and system for microparticle separation using chip
Provided is a microchannel chip, for microparticle separation, which can continuously separate microparticles, from a solution in which microparticles of different particle diameter are mixed, without needing to use an antibody or similar, and without causing clogging. Also provided are a microparticle separation method and a system for microparticle separation using the chip. Microparticles can be captured by using the microchannel chip for microparticle separation, the microchannel chip being characterised by being provided with a plurality of main channels and capture portions that are wider than the main channels and at least one of which is provided to each main channel.
US09968920B2 Strong acid catalyst composition
A catalyst prepared by polymerizing 0-98 weight % butylstyrene; 0-80 weight % vinyl toluene; 1.5-25 weight % divinyl benzene having 1-98 weight % of ethyl vinyl benzene; and 0-80 weight % styrene. Copolymer beads are made, sulfonated, and used as a catalyst.
US09968912B2 Method for manufacturing excretion disposal material and excretion disposal material
A method for manufacturing a granular excretion disposal material having a core portion and a covering layer that covers the core portion. The method includes: a granulating step of granulating the core portion by blending a core portion raw material containing pulp and highly absorbent resin, with water; a covering step of forming the covering layer by spraying a covering layer raw material containing pulp and highly absorbent resin, onto a surface of the core portion granulated in the granulating step; a drying step of drying a granular matter, in which the covering layer is formed in the covering step, with hot air; and a cooling step of cooling the granular matter dried in the drying step.
US09968903B2 Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays. The invention includes methods by which many physical, chemical or biological transformations can be implemented in serial or in parallel within each addressable through-hole of the devices. Additionally, the invention includes methods of analyzing the contents of the array, including assaying of physical properties of the samples.
US09968902B2 Microfluidic devices and methods for gene synthesis
Certain aspects of the present invention provide devices and methods for preparing oligonucleotides and for assembling nucleic acid molecules using microfluidic devices.
US09968901B2 Methods of sample preparation
The present disclosure provides methods, compositions, and kits for methods that can improve techniques nucleic acid analysis, and can allow for more reliable and accurate targeted, multiplexed, high throughput sequencing. The methods, compositions, and kits can be used for sequencing target loci of nucleic acid. The methods, compositions, and kits disclosed herein can be used for assisted de novo targeted sequencing. The methods, compositions, and kits disclosed herein can also be used for library labeling for de novo sequencing and phasing.
US09968895B1 Submersible aerator
A submersible aerator apparatus is disclosed. The apparatus uses injected air to create both aeration and mixing of a liquid. The apparatus is submersible and may be lowered into a container holding a liquid with suspended and coagulated solids. Air supplied to the apparatus is injected into the liquid which results in an upward flow of air bubbles and entrained liquid. This action mixes and aerates the liquid. A method of using a submersible air-injection aerator is also disclosed.
US09968893B2 Modular electronic carbonator fluid level control mechanism
A carbonator tank assembly is disclosed for use in a beverage machine that dispenses a carbonated beverage therefrom. The carbonator tank includes walls defining a carbonator tank interior. A probe assembly is provided for coupling in a gaseous and fluid-type manner to the walls of the carbonator tank. The probe assembly has no floats but includes electrical, elongated probes having removed ends configured to extend into the interior of the carbonator tank and near ends exposed exteriorly. An electronics module is adapt to fluidly enclose an electronics assembly therein and to receive an electrical cable carrying electrical energy from a remote source. Elements within the electronics module receive the electrical energy from the cable and provide it to the electrodes extending from the walls of the electronics module into the carbonator tank. The electrodes and the electronics module are adapted to removably couple to the probe assembly.
US09968888B2 Method for sealing hollow fiber membranes
The present invention is directed to a method of sealing the free end of a hollow fiber membrane for use in a single header filtration module by dipping the end of the membrane into a low-viscosity light-curable adhesive and curing the adhesive. The invention further encompasses the resulting sealed hollow fiber membrane with a diameter that is only slightly larger than the diameter of the unsealed membrane.
US09968885B2 Techniques for CO2 capture using sulfurihydrogenibium sp. carbonic anhydrase
Use of Sulfurihydrogenibium sp. carbonic anhydrase (SspCA) or mutants thereof for catalyzing the hydration reaction of CO2 into bicarbonate and hydrogen ions or catalyzing the desorption reaction to produce a CO2 gas is provided.
US09968881B2 Magnetic activated carbon and methods for preparing and regenerating such materials
A process for preparing magnetic activated carbons including the steps of a) treating an aqueous solution having a biomass hydrothermally at autogenic pressure at a temperature 180 and 250° C., under acidic conditions in the presence of iron ions, to obtain a precursor product, b) activating the precursor product obtained in step a) by mixing an activating agent at elevated temperatures between 550 and 850° C., for a period up to 9h. The disclosure also relates to magnetic activated carbon prepared according to the process and use of the carbon for separation and storage of gases and purification of liquids. A method for separation of particles from a liquid and/or a gas, and method for regenerating magnetic activated carbon by heating using an oscillating electromagnetic field are also disclosed.
US09968880B2 Regenerative absorbents of modified amines on nano-structured supports
The invention relates to regenerative, solid sorbent for adsorbing carbon dioxide from a gas mixture, with the sorbent including a modified polyamine and a nano-structured solid support. The modified polyamine is the reaction product of an amine and an aldehyde. The sorbent provides structural integrity, as well as high selectivity and increased capacity for efficiently capturing carbon dioxide from gas mixtures, including the air. The sorbent is regenerative, and can be used through multiple operations of absorption-desorption cycles.
US09968879B2 Ceramic honeycomb structure
A ceramic honeycomb structure having pluralities of flow paths partitioned by porous cell walls, (a) the cell walls having porosity of 50-63%; and (b) in a pore diameter distribution in the cell walls measured by mercury porosimetry, (i) pore diameters at cumulative pore volumes corresponding to particular percentages of the total pore volume being within specific ranges and having specific relationships; (ii) the difference between a logarithm of the pore diameter at a cumulative pore volume corresponding to 20% of the total pore volume and a logarithm of the pore diameter at 80% being 0.39 or less; and (iii) the volume of pores of more than 100 μm being 0.03 cm3/g or less.
US09968865B1 Multiple effect with vapor compression distillation apparatus
Multiple effects with vapor compression distillation apparatus includes a plurality of parallel cylinders or plates for recovery of heat having opposed evaporation and condensation faces for alternately evaporating and condensing. There are forward, backward and parallel feeding method to the upper end of the cylinders or plates for gravity flow along the evaporator face of the cylinders or plates with vapor condensing on the opposite condensation faces. Compressor is included as means for collecting and recovering the condensed product from the system. Alternate embodiments including a solar heat input system and other combined configurations.
US09968857B1 Game system including third party input
Methods, systems, devices, and media for controlling a network game in accordance with an input of a game spectator are provided. A network interface receives player input information from a game player and spectator input information from the game spectator. The network game is progressed in accordance with the player input information received by the network interface from the game player, and an aspect of the network game of the game player is controlled in accordance with the spectator input information received by the network interface. The spectator input information specifies the game player and the aspect of the network game of the game player to be controlled.
US09968856B1 Systems and methods of video game streaming with interactive overlay and additional data
Systems and methods to provide interactive overlays with video game streams can include a composing and broadcast system receiving a plurality of video game streams associated with a respective plurality of viewpoints of an online game from a game engine. The composing and broadcast system can select a video game stream of the plurality of video game streams, and transmit the selected video game stream to a live streaming system for streaming to a plurality of spectator client devices. The composing and broadcast system can stream game data indicative of positions of a graphical object in the selected video game steam receive to a plurality of spectator client devices. A client device receiving the selected video game stream and the game data can display an interactive overlay over displayed video frames. The interactive display can be temporally and spatially synchronized with a graphical object in the displayed video frames.
US09968853B2 Media system and method
A virtual world environment unit, and related methods, operable to simulate an actual live event in substantially real-time is disclosed. Also disclosed is an interactive media system configured to present a substantially real-time simulation of an actual live event involving a moveable object in an arena. Further disclosed is a method of providing and/or viewing a substantially real-time simulation of an actual live event involving a moveable object in an arena
US09968848B2 Method and apparatus for adapting applications over multiple devices
A method and apparatus that incorporate teachings of the present disclosure may include, for example, presenting at a display of a computer device a first graphical user interface depicting a game space of a gaming application, receiving a detected stimulation from a mobile communication device associated with a second graphical user interface depicting a virtual peripheral controller for capturing control information for controlling the gaming application, detecting a request to swap between the computer device and mobile communication device presentation of the first graphical user interface depicting the game space and the second graphical user interface depicting the virtual peripheral controller, and presenting at the display of the computer device an adaptation of the second graphical user interface depicting the virtual peripheral controller responsive to the detected request to swap. Additional embodiments are disclosed.
US09968846B2 Information processing apparatus, storage medium having stored therein information processing program, information processing system, and information processing method
A portable information processing apparatus includes a display, stereo loudspeakers, a pair of vibrators, and one or more processors. The pair of vibrators is provided on a left side and a right side of a main body of the information processing apparatus with respect to a center of the display. The one or more processors are configured to: generate sound signals to be output to the stereo loudspeakers, and output the sound signals; generate vibration signals for vibrating the pair of vibrators by vibrations, each having a plurality of frequency components, and output the vibration signals; and control an image to be displayed on the display.
US09968843B2 Communication system, method for controlling communication system, and program
In a communication system including a server (1) and a plurality of communication terminals (2) capable of communication with the server (1), based on a variety of parameters indicating the status of a space formed within a game playable by the user of each communication terminal (2) over the communication system, the server (1) transmits advisory information (132), which suggests the next action for the space, to the communication terminal (2). The communication terminal (2) displays a screen including the received advisory information (132).
US09968839B2 Golf swing measurement and analysis system
A golf club head includes a club face with at least one impact sensor, where the sensor has a passive piezoelectric element that is integrated into the club face, the passive piezoelectric element being able to generate a signal when an impact force is applied to the club face. An energy storage assembly includes a battery, a capacitor, or both. An energy harvesting assembly includes a signal divider with at least one input and at least two outputs, the at least two outputs providing a known ratio of a given input signal, wherein the at least one input of the signal divider is electrically coupled to one or more of the piezoelectric elements and a first of the at least two signal divider outputs is electrically coupled to the energy storage assembly.
US09968831B2 Golf balls having dual cores made of polybutadiene rubber/ionomer blends
A multi-piece golf ball comprising at least one component made of a polybutadiene rubber/ionomer resin blend is provided. The ball preferably contains a dual-core comprising an inner core and surrounding outer core layer. Preferably, the polybutadiene rubber/ionomer resin blend is used to form the outer core layer. Preferably, the outer surface hardness of the outer core layer is greater than the outer surface hardness of the inner core. The resulting ball has high resiliency and good impact durability.
US09968824B2 Exercise device providing user defined pedal movements
An exercise device for performing a variety of movement patterns. The exercise device has a pair of linkages, each including an upper link pivotally mounted to a frame and a lower link pivotally coupled to an upper link. A foot support is provided on a distal end of each lower link. A transfer system is coupled to the frame and both upper links for transferring both tensile and compressive forces. Separate torque elements are operably coupled to the frame and each lower link via a transfer member for independently resisting movement of the associated lower link.
US09968823B2 Treadmill with suspended tread belt
A treadmill deck may include a first side rail, a second side rail aligned with the first side rail, a first pulley connected to a first end of the first and second side rails, and a second pulley connected to a second end of the first and second side rails. A tread belt is disposed around the first pulley and the second pulley. Further, a first cover is connected to the first rail that spans at least a first portion of a first mid-region of the first rail and cantilevers over a portion of the tread belt that provides an unstable footing. Also, the tread belt moves with respect to the first cover.
US09968822B2 Rush simulating rowing device
A rowing device having a seat and track arrangement, a handle, and a resistance mechanism, with the seat track being disposed on a carriage. The carriage itself is movable relative to a base of the device and is drivable in a posterior and anterior direction. The device includes a controller operatively connected to a drive mechanism and to a seat position sensor. As the rower exercises, the controller sometimes generates an instruction to move the carriage in an anterior direction when the seat is at or near its posterior extreme position, to thereby simulate a “rush” circumstance as may be encountered on a crewed shell.
US09968814B2 Multipurpose fitness apparatus and method for assembly
A fitness apparatus and a method for assembly are disclosed. The fitness apparatus comprises a wheel assembly that includes a first circular side parallel to a second circular side, both bounded by a curved tread. Within the wheel assembly is an enclosable storage chamber. The fitness apparatus also includes an axis perpendicular to the first circular side and the second circular side, and when the fitness apparatus is in an abdominal exercise wheel configuration, at least a portion of the wheel assembly rotates around the axis. The fitness apparatus also includes a centerbore along the axis that supports a first removable handle and a second removable handle when the fitness apparatus is in the abdominal exercise wheel configuration.
US09968809B2 Portable air purifier
Provided is a portable air purifier, which includes: a mask part; a first connecting hose having one end connected to the mask part; a second connection hose in which the first connection hose is installed, and at least part of which has an opening for introducing external air; an air purification module that purifies the introduced external air to a predetermined temperature condition and discharges the purified air to the first connecting hose; and a power supply unit configured to supply power to the heater. Since the air purification module for removing poisonous gases or biochemical pollutants through a catalytic reaction of a metal catalyst layer can be semi-permanently used, the conventional inconvenience of carrying an extra canister is removed.
US09968800B2 Methods, compositions and apparatuses for treating psoriasis by phototherapy
Compositions, methods and apparatuses for phototherapy to treat skin disorders. In particular, described herein are methods, compositions, phototherapy dressings for use with phototherapy UV light applicators (sources) and phototherapy UV light applicators to treat skin disorders such as psoriasis.
US09968798B2 Transcranial magnetic stimulation device with body proximity sensors for the treatment of migraine headaches
A transcranial magnetic stimulation device has a capacitor for storing electrical energy. A wire coil delivers a magnetic pulse when the capacitor is actuated to cause current flow through the wire coil. A charging circuit charges the capacitor and there is a sensor which includes an unactivated state and an activated state. A control circuit connected to the body sensor initiates the delivery of a magnetic pulse when current from the capacitor flows through the wire coil.
US09968797B2 Electromagnetic thermal therapy
A portable, non-invasive device for providing therapeutic treatment to a joint to promote healing of the joint includes a cuff positionable around the joint. The cuff includes an electromagnetic stimulator configured to provide an electromagnetic field within the joint and at least one thermal therapy component including an activation circuit configured to activate the electromagnetic stimulator circuit, the thermal therapy component coupleable to the cuff, the thermal therapy component comprising at least two substances in separate compartments separated by a breakable barrier, wherein the at least two substances are configured to react upon mixing to produce thermal energy exchangeable with the joint.
US09968792B2 Implantable medical device housing having integrated features
One aspect is a housing for an implantable medical device, including first housing portion of metal, an intermediate portion of metal and having first and second sides opposite one another and having integrated features, and a second housing portion of metal. The first housing portion is sealed to the first side of the intermediate portion and the second housing portion is sealed to the second side of the intermediate portion thereby forming an housing internal space within first and second housing portions and containing the intermediate portion and its features, such that the features are hermetically sealed within the housing relative to an external space that is outside the housing.
US09968782B2 Selective, directable electrotaxis of precursor cells with biphasic electrical stimulation
A method and system for enhancing migration of precursor cells in a desired direction, comprising applying a biphasic monopolar electrical field to the precursor cells. The method and system can be used to treat injury or disease of neural or skin tissue.
US09968779B2 Apparatus for electrical therapies and testing procedure for electrical therapy
An apparatus for electrical therapies includes at least one electrocatheter, or an electroneedle, and at least one power supply device capable of electrically supplying the electrocatheter or electroneedle with at least one current suitable for carrying out at least one therapy. The apparatus includes at least one system for testing whether at least one desired point of application of the electrocatheter or electroneedle has been reached in the body of a patient. The testing system includes at least one device for emitting an electric testing current with which to electrically supply the electrocatheter or electroneedle before the start of the therapy, and at least one reading device, capable of providing at least one reading of at least one response generated in the patient by the electrostimulation with the electrocatheter or electroneedle through the testing current.
US09968770B2 Arrangement in a medical connector device
A medical transfer and connecting device (1) for connecting a first medical appliance with a second medical appliance, the device having an axial direction (A) and a radial direction (R) and comprising an outer part (2) having a first end (8) and a second end (9) with an end opening (10) and a bore (4) extending in the axial direction (A) between the first (8) end and the second end (9). An inner part (3) carrying a barrier member (12) and having a central canal (7) extends in the axial direction (A) and is telescopically arranged in the bore (4) in the outer part (2), the inner part (3) with the barrier member (12) being axially movable in the bore (4) in the outer part (2) between a shielding position in which the barrier member (12) is completely located within the bore (4) in the outer part (2) and a cleaning position in which the barrier member (12) is located with at least a portion of the barrier member (12) extending axially past the end opening (10) in the outer part (2).
US09968769B2 Connection device and blood component separation apparatus
To prevent a user from accidentally pricking the user with a hollow needle when separating blood components using a syringe and a connection device. A blood component separation apparatus has three syringes and a connection device. The connection device is attached to one syringe and is inserted into other syringes. The connection device has a first member to which a base end of a hollow needle is joined and a second member which is connected to the first member in such a manner as to be able to move relative to the first member. The second member is moved back and forth between a first position where a tip of the hollow needle is accommodated and a second position where the tip of the hollow needle is exposed. The second member has elastic portions which are elastically deformed in the movement from the first position to the second position. The elastically deformed elastic portions elastically energize the second member at the second position to the first position side with respect to the first member.
US09968764B2 Antiseptic applicator
An applicator assembly includes a head portion having a proximal, a distal end, and an interior portion defining a fluid chamber, a container slidably coupled to the body, a sealing member sealing an end of the container, and a lifting member, wherein the lifting member is mounted in the interior portion of the head portion and an interior of the container is placed in fluid communication with the application member by way of a fluid conduit that is formed around the sealing member from the container to the fluid chamber when the container is axially translated toward the head portion and the lifting member lifts the sealing member.
US09968762B2 Wire guide with multiple tips
A medical wire guide may include a mandril having a distal tip, a first coil coupled with the distal tip of the mandril, and a second coil configured to releasably engage with the mandril or the first coil. The second coil comprises a distal tip and defines an inner cavity dimensioned to contain a distal tip of the first coil when the second coil is engaged with the mandril or the first coil.
US09968759B2 Devices and methods for perfusing an organ
The present invention provides devices and methods for use in the perfusion of organs and anatomical regions. In one aspect the present method provides a percutaneously deliverable device for supporting a vessel in a human or animal subject including means for supporting the vessel during delivery of a fluid thereto or collection of a fluid therefrom. In another aspect the invention provides a method for delivery or collection of a fluid to or from an organ or anatomical region in a human or animal subject, the method including the step of supporting a vessel associated with the organ or anatomical region. The devices and methods may be used to deliver, remove or recirculate a therapeutic agent to an organ or anatomical region.
US09968751B2 Method and apparatus for resolving upper airway obstruction, resistance or instability
A CPAP apparatus has a variable rise time (iii) from a base level of positive air pressure during expiration (EPAP) to a higher level during inspiration (IPAP). The rise time is adjusted in order to reduce obstruction, resistance or instability in the upper airway.
US09968744B2 Pen-type injector
The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set a delivery dose. An injector may include a housing, the cartridge containing a medicinal product, the cartridge being retained within the housing, a dose dial sleeve for selecting a dose of the medicinal product to be expelled, and a piston rod for expelling the selected dose of the medicinal product. The housing may be a unitary housing within which the dose dial sleeve for selecting the dose and the piston rod for expelling the selected dose are moveably retained. Alternatively, the injector may include the housing, the piston rod, an insert located in the housing and through which the piston rod may rotate, a ratchet, the dose dial sleeve, a drive sleeve, a button located on the drive sleeve and rotatable with respect to the drive sleeve, and a clutch which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.
US09968728B2 Motorized irrigation system
A portable irrigation system comprising a reservoir for an irrigating liquid; a probe for arrangement in a user; and an electrical system.
US09968727B2 Systems, devices, and methods for organ retroperfusion along with regional mild hypothermia
Systems, devices, and methods for organ retroperfusion along with regional mild hypothermia. In at least one embodiment of a method of organ perfusion of the present disclosure, the method comprises the steps of positioning at least part of a first catheter having a cannula within an artery of a patient, the first catheter configured to permit arterial blood to flow therethrough and further configured to permit a portion of the arterial blood to flow through the cannula, positioning at least part of a second catheter within a vein of the patient at or near a target organ, the second catheter configured to receive some or all of the portion of the arterial blood, connecting the cannula of the first catheter to a portion of the second catheter so that some or all of the portion of the arterial blood flowing through the cannula is provided into the vein to treat a condition or disease of the target organ, and reducing and/or regulating a temperature of blood flowing through the cannula using a regional hypothermia system operably coupled to the cannula.
US09968723B2 System and method to efficiently clean a blood filter
A method for cleaning a blood filter includes: (i) pumping a physiologically safe fluid back and fourth through the insides and/or the outsides of a plurality of hollow fiber membranes of the blood filter to remove or loosen blood residuals, such as blood clots, proteins and/or biological fluid; (ii) injecting air into the physiologically safe fluid to form an air/fluid mixture; (iii) pumping the air fluid mixture through the insides and/or outsides of the plurality of the hollow fiber membranes of the blood filter to further or remove or loosen blood residuals therefrom; and (iv) removing the air/physiologically safe fluid mixture along with the removed or loosened blood residuals to drain.
US09968715B2 Method for depositing coloured markers made from titanium oxides on medical technology products and coating system for producing coated materials
The invention relates to medical technology products, for example a medical implant or a medical instrument, having colored markings based on titanium oxides, to the use of coatings based on titanium oxides for the production of coated materials, such as medical technology products, in particular for titanium oxide-based coating for the colored marking of the surface of medical technology products, and to a method for depositing colored markings based on titanium oxides on medical technology products.
US09968712B1 Organic/inorganic hybrid-biodegradable porous polymer scaffolds and preparation method thereof
Provided is an organic/inorganic hybrid-porous biodegradable polymer scaffold, which includes basic ceramic nanoparticles, an animal tissue or cell-derived bioactive first extracellular matrix material, and a biodegradable polymer and in which inner walls of pores are coated with a second extracellular matrix material.
US09968711B2 Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same
A method of treating bone deficiencies includes applying a biocompatible structure to an implant surgical site. The biocompatible structure includes multiple polymer layers stacked to have a predetermined shape, multiple bone particle layers disposed between each of two neighboring polymer layers of the multiple polymer layers, and a coating surrounding the polymer layers and bone particle layers. Each of the polymer layers is formed with a polymer and first tissue forming nanoparticles. The predetermined shape is configured to conform to the implant surgical site.
US09968710B2 Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition
Use of a pharmaceutical composition for the local treatment or prevention of a tissue infection at an infection site, the pharmaceutical composition comprising at least two different antibiotics of group A or pharmaceutically acceptable derivatives thereof, or an antibiotic of group A and at least one antibiotic of group B or pharmaceutically acceptable derivatives thereof. Group A comprises primarily intracellular active antibiotics working as inhibitor of bacterial RNA polymerase; as inhibitor of gyrase; or as inhibitor of bacterial protein synthesis. Group B comprises primarily extracellular active antibiotics working as inhibitor of bacterial cell wall synthesis; or inhibitor of bacterial protein synthesis; or by direct destabilization or rupture of the bacterial cell wall.
US09968706B2 Nerve regeneration employing keratin biomaterials
A keratin hydrogel matrix serves as an effective acellular scaffold for axonal regeneration and facilitates functional nerve recovery.
US09968702B2 Air freshener
The air freshener consists of a small box formed by coupling together two parts (1, 2) in the form of box halves that can be tightly fitted together, with a perfume-impregnated cellulose block (5) between them. The cellulose block (5) is separated from the bottoms of the boxes and from the side walls by ledges (6) provided on the bottoms of both the female part (1) and the male part (2), and by partitions (7) provided on the male part (2), near the side walls thereof. The box has windows for air inlet (9) and for outlet (8) of the air impregnated with the perfume contained in the cellulose block (5). On the outside of the box there are conformations defining a dovetail joint (10) for securing a clip (11) which, when released from this mounting formed by the conformations (10), can be coupled to an outer recess in the bottom of the male part (2).
US09968694B2 Compositions and methods for non-invasive imaging
The present invention relates to a novel composition useful in targeted diagnostic and/or therapy of a target site, such as cancerous tissue. The composition and methods disclosed herein find particular use in diagnosing and imaging cancerous tissue. The present invention provides a new diagnostic tool for the utilization of positron emission tomography (PET) imaging technique.
US09968681B2 Silylated biomolecule-based hydrogel for culturing cardiomyocytes and stem cells, and use of the hydrogel thereof for treating heart failure
The present invention relates to the use of an hydrogel comprising silylated biomolecule for the three-dimensional culture of cardiomyocytes or stem cells which are able to differentiate into cardiomyocytes, and to an aqueous composition comprising i) cardiomyocytes or stem cells which are able to differentiate into cardiomyocytes, and ii) a hydrogel comprising silylated biomolecule, for use for treating heart failure, in particular heart failure following myocardial infarction.
US09968679B2 Clear aqueous solution
The present invention provides a stable and clear aqueous liquid preparation containing (3-{2-[4-isopropyl-2-(4-trifluoromethyl)phenyl-5-thiazolyl]ethyl}-5-methyl-1,2-benzisoxazol-6-yl)oxyacetic acid or a pharmaceutically acceptable salt thereof as an active ingredient, and benzalkonium chloride represented by the formula: [C6H5CH2N(CH3)2R]Cl wherein R is an alkyl group having 8-18 carbon atoms.
US09968676B2 Subcutaneous anti-HER2 antibody formulations and uses thereof
The present invention relates to a highly concentrated, stable pharmaceutical formulation of a pharmaceutically active anti-HER2 antibody, such as e.g. Trastuzumab (HERCEPTIN™), Pertuzumab or T-DM1, or a mixture of such antibody molecules for subcutaneous injection. In particular, the present invention relates to formulations comprising, in addition to a suitable amount of the anti-HER2 antibody, an effective amount of at least one hyaluronidase enzyme as a combined formulation or for use in form of a co-formulation. The formulations comprise additionally at least one buffering agent, such as e.g. a histidine buffer, a stabilizer or a mixture of two or more stabilizers (e.g. a saccharide, such as e.g. α,α-trehalose dihydrate or sucrose, and optionally methionine as a second stabilizer), a nonionic surfactant and an effective amount of at least one hyaluronidase enzyme. Methods for preparing such formulations and their uses thereof are also provided.
US09968673B2 Immunogenic composition in emulsion form comprising two dispersed phases, one comprising an antigen and the other comprising an immunostimulating agent
The application relates to an immunogenic composition comprising a continuous aqueous phase and at least two dispersed phases 1 and 2 as droplets, wherein the dispersed phase 1 comprises a surfactant 1 bearing an antigen and the dispersed phase 2 comprises an immunostimulating agent 2, to its preparation method and its uses, notably for producing antibodies, as a drug, as a vaccine or in an immunization method.
US09968672B2 IDNA vaccines and methods for using the same
Described herein are iDNA vectors and vaccines and methods for using the same. The iDNA generates live attenuated vaccines in eukaryotic cells in vitro or in vivo for pathogenic RNA viruses, particularly yellow fever virus and Venezuelan equine encephalitis virus. When iDNA is injected into the vaccine recipient, RNA of live attenuated virus is generated by in vivo transcription in the recipient's tissues. This initiates production of progeny attenuated viruses in the tissues of the vaccine recipient, as well as elicitation of an effective immune response protecting against wild-type, non-attenuated virus.
US09968670B2 Influenza virus vaccines and uses thereof
Provided herein are chimeric influenza hemagglutinin (HA) polypeptides, compositions comprising the same, vaccines comprising the same, and methods of their use.
US09968667B2 Targets and compositions for use in decontamination, immunoprophylaxis, and post-exposure therapy against anthrax
The present invention relates to the decontamination of anthrax spores, prophylaxis and treatment of anthrax infections and, more particularly, to compounds that act as specific inhibitors of B. anthracis germination/outgrowth-associated proteins, methods and means for making such inhibitors and their use as pharmaceuticals and/or vaccines. The invention also relates to the prophylaxis and treatment of anthrax infections and, more particularly, to vaccines and compositions that comprise B. anthracis antigens, epitopes, proteins, or nucleic acid molecules, including anthrax protective antigen, anthrax lethal factor, anthrax edema factor and anthrax proteins associated with spore germination and outgrowth, as well as methods and means for making such compositions and their use pharmaceuticals and/or vaccines.
US09968665B2 Anti-malaria compositions and methods
Described herein are multilayer films that include modified polypeptide epitopes from Plasmodium falciparum, specifically a modified T* epitope. The multilayer films are capable of eliciting an immune response in a host upon administration to the host. The multilayer films can include at least one designed peptide that includes the modified T* polypeptide epitope from a Plasmodium protozoan.
US09968662B2 Factor VII composition
A stable pharmaceutical composition in liquid form or in solid form, containing factor VII. The composition is free of mannitol, sucrose, and any antioxidant.
US09968660B2 Method of bone regeneration or bone augmentation
The present invention provides a means effective for bone regeneration or bone augmentation.Provided is a method of bone regeneration or bone augmentation, comprising: implanting a porous composite at a site in need of the bone regeneration or bone augmentation, and administering parathyroid hormone (PTH) to a subject in need of the bone regeneration or bone augmentation, wherein the porous composite comprises calcium phosphate.
US09968652B2 Optically-controlled CNS dysfunction
Provided herein are animals expressing light-responsive opsin proteins in the basal lateral amygdala of the brain and methods for producing the same wherein illumination of the light-responsive opsin proteins causes anxiety in the animal. Also provided herein are methods for alleviating and inducing anxiety in an animal as well as methods for screening for a compound that alleviates anxiety in an animal.
US09968647B2 Small molecule conjugates for intracellular delivery of biologically active compounds
The invention provides novel compounds and conjugates of these compounds useful for the delivery of biologically active substances. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to a delivery polymer to achieve in vivo mRNA knock down are disclosed therein.
US09968640B2 Method for treating or preventing a pancreatic dysfunction
The present invention provides a method for improving pancreatic function in a subject in need thereof, the method comprising administering to the subject STRO-1+ cells and/or progeny cells thereof and/or soluble factors derived therefrom. The method of the invention is useful for treating and/or preventing and/or delaying the onset or progression of a disorder resulting from or associated with pancreatic dysfunction, e.g., resulting from abnormal endocrine or exocrine function of the pancreas.
US09968637B2 Dopaminergic neurons differentiated from pluripotent stem cells and uses thereof
The present invention provides populations of neural cells derived from pluripotent cells, and methods for making and using the same. Disclosed herein are methods for generating dopaminergic neurons in vitro using a combination of agents that cause differentiation of the pluripotent cells into dopaminergic neurons. Also disclosed are methods for treating a neurodegenerative disease in a patient by generating dopaminergic neurons in vitro, and transplanting them into the brain of the patient, such that the dopaminergic neurons are sufficient to reduce or eliminate the symptoms of the neurodegenerative disease.
US09968633B2 Stimuli responsive compositions for iron chelation
The present technology provides new compositions comprising at least one cross-linked co-polymer. In some embodiments, the polyacrylamide co-polymer comprises water soluble subunits, cross-linking subunits, and iron chelating subunits. In other embodiments, the co-polymer comprises water soluble units, cross-linking subunits, and substituted subunits, which can be conjugated with iron-chelating agents. When these new particles are exposed to certain environments, such the presence of strong acids or oxidation agents, these particles are capable of breaking up so that the iron chelating agents can chelate iron or other metals from their environments. Methods to prepare these new compositions are also provided. These compositions or compositions comprising nanogels of the present technology may be used to treat metal overload conditions such as iron overload resulting from chronic transfusions.
US09968630B2 Pharmaceutical combination comprising a CIP2A silencing agent for use in the treatment of a hyperproliferative disorder, preferably one with impaired P53 function
The invention is based on a finding that silencing CIP2A (KIAA1524) gene sensitizes cancer cells for apoptosis-inducing activity of certain small molecule chemotherapeutic agents. Thus, the invention is directed to a respective combination therapy, sensitization method and pharmaceutical compositions. The invention further relates to a method of selecting cancer therapy for a subject on the basis of CIP2A and p53 expression and/or protein activity in a sample obtained from said subject.
US09968624B2 Depression treatment agent
The invention provides an agent for treating depression, which contains N-acetyl-D-mannosamine, and a pharmaceutical composition for treating depression, which contains an effective amount of N-acetyl-D-mannosamine and a carrier acceptable as a medicament.
US09968623B2 Prepackaged sterile syringe or containers with various substance concentrations with or without bioactive reagent
A prepackaged sterile syringe or bottle with various concentrations of tissue and organ biologically stimulating reagents i.e., dextrose, various anthocyanins, anthocyanidins and/or their various metabolites (i.e., protocatechuic acid) as the base, can be used as a product and service not otherwise available to those practicing prolotherapy. A selected bioactive agent could be added to enhance the treatment effectiveness. The prepackaged sterile syringe or bottle can be produced in standardized concentrations of reagents and can be produced in a regulated facility to meet all the government standards of oversight necessary to insure a safe sterile product of uniform nature. The prepackaged sterile syringe or bottle provides cost savings as well as enhanced quality control, time and labor efficiency at the treatment sites.
US09968620B2 Methods of treating lymphoma using thienotriazolodiazepine compounds
A method of treating lymphoma in a mammal comprises the step of: administering to a patient a pharmaceutical acceptable amount of a compound being a thienotriazolodiazepine compound of the Formula (1) wherein R1 is alkyl having a carbon number of 1-4, R2 is a hydrogen atom; a halogen atom; or alkyl having a carbon number of 1-4 optionally substituted by a halogen atom or a hydroxyl group, R3 is a halogen atom; phenyl optionally substituted by a halogen atom, alkyl having a carbon number of 1-4, alkoxy having a carbon number of 1-4 or cyano; —NR5—(CH2)m—R6 wherein R5 is a hydrogen atom or alkyl having a carbon number of 1-4, m is an integer of 0-4, and R6 is phenyl or pyridyl optionally substituted by a halogen atom; or —NR7—CO—(CH2)q—R8 wherein R is a hydrogen atom or alkyl having a carbon number of 1-4, n is an integer of 0-2, and R8 is phenyl or pyridyl optionally substituted by a halogen atom, and R4 is —(CH2)a—CO—NH—R9 wherein a is an integer of 1-4, and R9 is alkyl having a carbon number of 1-4; hydroxyalkyl having a carbon number of 1-4; alkoxy having a carbon number of 1-4; or phenyl or pyridyl optionally substituted by alkyl having a carbon number of 1-4, alkoxy having a carbon number of 1-4, amino or a hydroxyl group or —(CH2)b—COOR10 wherein b is an integer of 1-4, and R10 is alkyl having a carbon number of 1-4, or a pharmaceutically acceptable salt thereof or a hydrate or solvate thereof. The lymphoma to be treated is diffuse large B-cell lymphom (DLBCL) specifically selected from activated B-cell DLBCL (ABC-DLBCL) and germinal B-cell DLBCL (GBC-DLBCL).
US09968609B2 Sildenafil solutions and methods of making and using same
A pharmaceutical composition comprising: (a) a liquid carrier comprising water and at least 20% of at least one alcohol; and (b) sildenafil citrate dissolved in said liquid carrier at a concentration of at least 7 mg/ml.
US09968599B2 Platinum compounds that inhibit constitutive STAT3 signaling and induce cell cycle arrest and apoptosis of malignant cells
The subject invention concerns a compound and compositions having activity as an inhibitor of Stat3 protein and methods of using the compound and compositions. In one embodiment, a compound of the invention has the structure shown in formula I, formula II, or formula III. The subject invention also concerns methods of using the compounds and compositions of the invention.
US09968598B2 Process of making stable abuse-deterrent oral formulations
The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
US09968597B2 Methods and uses of quinoline derivatives in the treatment of soft tissue sarcomas and pharmaceutical compositions for treatment of same
The present invention addresses methods and uses of quinoline derivatives in the treatment of tumors and pharmaceutical compositions for treatment of same. Specifically, the present invention involves a method and applications for the use of the quinoline derivative 1-[[[4-(4-fluoro-2-methyl-1H-indol-5-yl)oxy-6-methoxyquinolin-7-yl]oxy]methyl]cyclopropylamine in the treatment of soft tissue sarcomas and pharmaceutical compositions for treatment of same.
US09968589B2 Method of treating disease by auricular anesthesia of cranial nerves
Methods for treating a variety of diseases that comprises performing auricular anesthesia of various cranial nerves. A pharmaceutical composition is administered to an ear canal of a subject in need of such treatment, the composition including an analgesic and/or at least one anesthetic. Compositions useful in the taught methods are also provided.
US09968588B2 Use of NK-1 receptor antagonists in pruritus
The invention relates to methods for treating pruritus with NK-1 receptor antagonists such as serlopitant. The invention further relates to pharmaceutical compositions comprising NK-1 receptor antagonists such as serlopitant. In addition, the invention encompasses treatment of a pruritus-associated condition with serlopitant and an additional antipruritic agent, and the use of serlopitant as a sleep aid, optionally in combination with an additional sleep-aiding agent.
US09968579B2 ATRA for modulating Pin1 activity and stability
The present disclosure describes how all-retinoic acid (ATRA) binds and inhibits Pin1 activity and induces degradation of the activated Pin1 monomer selectively in cancer cells. Identification of the binding mechanism of ATRA with Pin1 confirm ATRA binding specificity to Pin1 residues in the PPIase active site, thus demonstrating that drug-induced Pin1 ablation has potent anticancer activity, such as in acute promyelocytic leukemia (APL), by inducing PML-RARa degradation, as well as against other types of cancer and diseases that are associated with Pin1 overexpression, such as aggressive triple negative breast cancer, lupus, asthma, cocaine addiction, among others, due to their unique ability to simultaneously block numerous cancer-driving pathways, with relatively lower toxicity. The present disclosure also provides a rationale for developing sustained released ATRA-containing formulations. ATRA-containing formulations may be used in combinations with other existing therapies including chemotherapy or molecularly targeted drugs and other standard of care.
US09968578B2 Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
US09968574B2 Treatment of MCI and Alzheimer's disease
The present invention provides, among other things, therapeutic compositions and methods that can effectively treat, slow or prevent a neurological disease (e.g., a neurodegenerative disease, e.g., mild cognitive impairment (MCI) or Alzheimer's disease (AD)), in particular, based on therapeutically effective amount of nifedipine, oxidized or nitroso nifedipine derivatives, lactam (e.g., a compound of formula (Ic) or (Ic-i), e.g., NFD-L1), thyroxine (T4), triiodothyronine (T3) and combinations thereof.
US09968566B2 Pharmaceutical composition for prophylaxis and/or treatment of corneal and conjunctival diseases or presbyopia containing stilbene compound as active ingredient
A pharmaceutical composition for prophylaxis and/or treatment of a corneal and conjunctival disease or presbyopia, the composition containing a compound represented by Formula (I), or a salt thereof or a prodrug thereof as an active ingredient, wherein m and n are each independently an integer of 0 to 5; m+n≥1; and each aromatic ring of the compound represented by Formula (I) may be substituted.
US09968560B2 Composition for preparing soft capsule shell
Provided is a composition for preparing a soft capsule shell that includes a non-animal material, and more particularly a composition for preparing a soft capsule shell, which includes modified starch composed of modified waxy corn starch and modified waxy potato starch, thereby realizing a soft capsule shell having appropriate hardness and elastic strength and delaying a browning phenomenon. The composition includes modified starch composed of modified waxy corn starch and modified waxy potato starch at a weight ratio of 2:8 to 8:2, a modified starch hydrolysate, a gelling agent, a plasticizer and purified water.
US09968559B2 Pharmaceutical formulation containing gelling agent
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together with one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid; the dosage form providing a therapeutic effect for at least about 12 hours when orally administered to a human patient.
US09968554B2 Modified drugs for use in liposomal nanoparticles
Drag derivatives are provided herein which are suitable for loading into liposomal nanoparticle carriers. In some preferred aspects, the derivatives comprise a poorly water-soluble drag derivatized with a weak-base moiety that facilitates active loading of the drag through a LN transmembrane pH or ion gradient into the aqueous interior of the LN. The weak-base moiety can optionally comprise a lipophilic domain that facilitates active loading of the drag to the inner monolayer of the liposomal membrane. Advantageously, LN formulations of the drag derivatives exhibit improved solubility, reduced toxicity, enhanced efficacy, and/or other benefits relative to the corresponding free drags.
US09968552B2 Pharmaceutical oral dosage form comprising a non-steroidal anti-inflammatory drug, and having good palatability
Oral pharmaceutical dosage form comprising tromethamine and a NSAID selected from the group comprising ibuprofen, naproxen and flurbiprofen, characterized in that it also comprises a compound selected from the group comprising glycine, vitamin B6 and mixtures thereof.
US09968548B2 Dental hard chew supplements containing antimicrobial actives
A hard chew matrix containing antimicrobial actives, such as nanosilver, curcumin and propolis for use in dogs and other animals is disclosed.
US09968542B2 Makeup base for skin removable with warm water
A makeup base for skin that is applied to the skin before applying a makeup cosmetic is provided. The makeup base is not smeared or removed by sweat or cold water, but, when rubbed with warm water, is easily removed from the skin together with the makeup cosmetic and without using a cosmetic cleanser. The makeup base includes a water-containing aqueous phase as a continuous phase, which includes (a) a vinyl acetate polymer, (b) polyhydric alcohol, and (c) a hydrophilic nonionic surfactant. The (a) the vinyl acetate polymer is 0.5 to 7 mass % in the makeup base and is dispersed as particles in the aqueous phase, (b) the polyhydric alcohol is 0.5 to 5.5 parts by mass relative to 1 part by mass of (a) the vinyl acetate polymer, and (c) the hydrophilic nonionic surfactant is 1 to 5 mass % in the makeup base.
US09968537B2 Anti-dandruff compositions and hair care formulations containing zinc pyrithione and quaternary ammonium salt
The present invention discloses a stable biocidal composition with enhanced antifungal activity at low concentration of active (s) and a process for preparing the same. The composition comprises: zinc pyrithione, C8-C18 quaternary ammonium salt (preferably cetylpyridinium chloride), water miscible glycol/polyol/glycol ether/lactam, organic amine and/or alkanol amine. The composition can be formulated into: hair care formulations, antidandruff hair care formulations, water based paints, coatings, adhesives, hard surface cleaners, fabric care compositions, wood products, plastic products and medical products. The biocidal compositions and the resulting formulations are transparent or opaque and are stable at varying pH and humidity conditions.
US09968535B2 Personal care compositions comprising undecyl sulfates
A personal care composition comprising a dermatologically acceptable carrier, and from about 3 wt % to about 40 wt % of at least one undecyl sulfate compound selected from the group consisting of: a) R1—O(CH2CHR3O)y—SO3M; b) CH3—(CH2)z—CHR2—CH2—O(CH2CHR3O)y—SO3M; and c) mixtures thereof; where R1 represents CH3(CH2)10, R2 represents H or a hydrocarbon radical comprising 1 to 4 carbon atoms such that the sum of the carbon atoms in z and R2 is 8, R3 is H or CH3, y is 0 to 7, the average value of y is about 1 when y is not=0, and M is a mono-valent or di-valent, positively-charged cation.
US09968534B2 Anionic direct dye having a tetraalkylammonium counterion, dyeing composition comprising them and method for dyeing keratinous fibres starting from these dyes
The invention relates to the dyeing of human keratinous fibers, in particular the hair, using anionic direct dyes or acid dyes having a tetraalkylammonium counterion of formula (I), with Col(−)m, R1, R2, R3, R4, m, and n as defined in the description. A subject-matter of the invention is a dyeing composition comprising an anionic dye of formula (I) and a method for dyeing keratinous fibers, such as the hair, employing the said composition. A subject-matter of the invention is likewise novel dyes of formula (I) and their uses for the coloring of keratinous fibers. This composition makes it possible to obtain a chromatic, powerful and particularly persistent coloring on keratinous fibers.
US09968522B2 Gravity timer reset mechanism
A medicine container timing apparatus and method of use. The apparatus includes a container, a tilt switch, an electronic timer, and cap with a flange. Within the tilt switch are a gravity response member and a pair of electrical contacts. The cap flange extends into the tilt switch chamber and prevents the electrical contacts resetting the timer by forming a supporting barrier between the contacts and gravity response member. If a user tilts the container when the cap is off, the gravity response member falls onto the pair of electric contacts and resets the electronic timer. However, if the cap is on the container, the flange prevents the gravity response member from causing the electrical contacts to contact each other. The electronic timer therefore only displays the time since the container was last tilted with its cap off.
US09968516B2 Closure with sequenced double release
A child-resistant closure for a container. The closure has a first groove and a second groove formed into a base. A cap covers an opening in the base. The cap can rotate between a closed position, a primed position and an open position. The cap has a nub that engages the first groove on the base, when in its closed position, engages the second groove on the base when in its primed position, and is free of any groove when in its open position. A mechanical activator is coupled to the base with a teeter connection. The mechanical activator displaces the cap from the closed position to the primed position when a first section of the mechanical activator is depressed. The mechanical activator displaces the cap from the primed position to the open position when a second section of the mechanical activator is depressed.
US09968511B2 High frequency chest wall oscillation system
A therapy system is operable to deliver at least one respiratory therapy to a patient. For example, therapy system may be operable to deliver any one or more of the following therapies: a high frequency chest wall oscillation (HFCWO) therapy, a positive expiratory pressure (PEP) therapy, a nebulizer therapy, an intermittent positive pressure breathing (IPPB) therapy, a cough assist therapy, a suction therapy, a bronchial dilator therapy, and the like. The therapy system is contained in a housing supported by a mobile stand.
US09968506B2 Therapeutic system and method for flexing and extending metacarpal and phalangeal joints
A therapeutic system and method flexes, extends, and exercises the metacarpal and phalangeal joints of an affected hand. The system comprises a therapeutic glove that receives an affected hand and adjustably applies movement to the fingers and thumb in a first forward direction to form a flexion position, and a second rearward direction to form an extension position. The position of the fingers and thumb as well as the amount of pressure applied is controlled by manipulating restraining members to pull and restrain the fingers and thumb and then attaching to a corresponding body and wrist portion on the glove. The extent of the pulling, including the pressure applied to the metacarpal and phalangeal joints, is fixed, adjustable, and easily releasable. A secondary therapeutic glove compensates for the tactile perception feedback from an unaffected hand. A therapeutic pain relief modality is applied prior to donning the glove.
US09968493B2 Methods and apparatuses for moving and/or transferring multiple discrete articles
Methods and apparatuses for moving and/or transferring discrete articles are described. In particular, the methods and apparatuses relate to flexible arrangements to move and/or transfer discrete articles that vary in size and/or shape with minimal to no change in equipment.
US09968489B2 Reduced-pressure wound dressings
Systems, methods, and dressings for treating a linear wound, such as an incision, on a patient are presented. The systems, dressings, and methods involve a sealed wound dressing assembly that helps form a fluid seal around the linear wound while simultaneously encompassing a subcutaneous delivery conduit to deliver fluid to or from a subcutaneous tissue site. In one instance, a reduced-pressure interface is used to allow the subcutaneous delivery conduit to pass through tissue at or near the linear wound and through a wound dressing assembly to a drainage receptacle.
US09968487B2 Glasses structure
A glasses structure comprises a main body and a sub-frame assembled at the rear of a lens of the main body. The inner surface of a frame body of the sub-frame is attached with a pad, which pad is formed with an upper contact portion and a central contact portion corresponding to the upper edge and the central shape of the frame body. Two nose pieces are formed at the both sides of the central contact portion of the pad, and the upper contact portion of the pad are respectively contacted with the user's nose and forehead to avoid pain when the user wears the glasses. Furthermore, the colored and patterned frame body of the sub-frame is shown from the transparent lens of the main body, whereby the glasses with suitable color and pattern being chosen to dress with the user's clothes and style, increasing the user's fashion and beauty.
US09968472B2 Transluminal angioplasty devices and methods of use
A percutaneous transluminal angioplasty device includes a catheter defining one or more lumens. A filter is coupled to the catheter adjacent a distal end of the catheter, and the filter is movable between an unexpanded and expanded configuration via a filter activation wire that extends through a lumen. An expandable balloon is coupled to the catheter proximally of the filter, and a stent is disposed over at least a portion of the balloon. To deploy the stent to a target site, the filter is first moved into its expanded position via the filter activation wire. Then, the stent is expanded, and the balloon is inflated to expand the stent further radially. The balloon is then deflated, the filter is contracted, and the catheter, balloon, and filter are removed from the body.
US09968466B2 Prosthetic foot with programmable movement
A programmable prosthetic foot includes a heel member simulating a heel portion of a human foot. The heel member has an elongated heel member shaft extending in a vertical direction. The foot also includes a forefoot member simulating a forefoot portion of a human foot. The forefoot member has an elongated forefoot member shaft extending in the vertical direction. A sensor on the foot detects compressive force on the heel member shaft and/or forefoot member shaft during a step. An actuator on the foot imparts vertical translation to the heel member shaft and/or forefoot member shaft. An electronic controller in operable communication with the actuator includes program instructions for operating the actuator by imparting the vertical translation to the heel member shaft and/or forefoot member shaft as a function of the compressive force detected by the sensor.
US09968465B2 Femoral component trial for knee joint
A femoral component trial for a knee joint of the present invention includes a trial body. The trial body includes a medial condyle and a lateral condyle that are located away from each other on an external surface, a through hole that is located between the medial condyle and the lateral condyle and has an approximately rectangular shape whose long side is an outer edge of an inner wall located along a back-and-forth direction and whose short side is an outer edge of an inner wall located along a right-and-left direction in an external surface view, a first guide slit that is located ahead of and above the through hole and extends in the right-and-left direction, and four second guide slits respectively extending from four corner parts of the through hole and along the long side.
US09968464B2 Spinal fusion system
A spinal fusion system may include an interbody fusion cage, a fixation plate, and an implanter. The interbody fusion cage may include a proximal region, a distal region opposite the proximal region, a superior region, an inferior region opposite the superior region, and an open volume between the proximal and distal regions. The superior and inferior regions are located between the proximal and distal regions and are configured such that, when the interbody fusion cage is implanted in the disc space, the superior region contacts the inferior end plate and the inferior region contacts the superior end plate. The fixation plate is receivable in the open volume of the interbody fusion cage and includes a superior blade and an inferior blade. At least one of the blades includes a first opening defined therein. The fixation plate is displaceable between a non-deployed state and a deployed state.
US09968462B2 Articulating expandable intervertebral implant
A spacer for separating bones of a joint, the spacer includes a frame having a longitudinal axis, and ramped surfaces. An endplate configured to engage a bone of the joint has ramped surfaces mateable with the ramped surfaces of the frame. When the endplate is moved relative to the frame in a direction along the longitudinal axis of the frame, the endplate is moved in a direction away from the frame to increase the height of the spacer. A second endplate configured to engage a second bone of the joint can be similarly configured.
US09968456B2 Customized acetabular cup positioning guide and method of generating and employing such a guide
Implementations described and claimed herein provide an arthroplasty system and methods for positioning an acetabular cup implant. In one implementation, the system includes a shape-match hip guide having a patient specific mating region that is a negative of the surface contour of the inside surface of the patient's acetabular cup, and a directional rod that extends generally along the axis of the patient's femoral head and femoral neck. They system can additionally include an outrigger or silo device to aid in the alignment of surgical tools for preparing and implanting of the prosthetic acetabular cup in the patient's acetabular cup. Related methods are also disclosed herein for generating a shape-match guide and implanting an acetabular cup with the guide.
US09968454B2 Techniques for guide-wire based advancement of artificial chordae
Apparatus is provided, comprising (1) a guide member, (2) a tissue-adjustment mechanism having (a) an upper surface and a lower surface, (b) at least one first opening at the upper surface, (c) at least one second opening at the lower surface, and (4) a channel extending between the first and second openings, the channel facilitating advancement of the tissue-adjustment mechanism along the guide member; and (3) at least one repair chord coupled at a first portion thereof to the tissue-adjustment mechanism and having at least a first end that is configured to be coupled to a portion of tissue of a patient, the repair chord being configured to adjust a distance between the portion of tissue and the tissue-adjustment mechanism, in response to adjustment of the repair chord by the tissue-adjustment mechanism. Other embodiments are also described.
US09968452B2 Annuloplasty ring delivery cathethers
Apparatus is provided, including a first catheter having a distal end portion transluminally advanceable to a vicinity of an anatomical site, a second catheter having a distal end portion advanceable through a first lumen and out of the first lumen, and a longitudinal implant, advanceable through the second lumen and out of the second lumen. The first and second catheters are assembled to facilitate sliding of the first and second catheters and of the implant, to configure them to assume a multi-bend formation having first and second bends separating first, second, and third domains. The first domain includes parts of the first and second catheters. The second domain includes the distal end portion of the second catheter, part of the implant, and none of the first catheter. The third domain includes part of the implant and none of the first nor second catheters. Other embodiments are also described.
US09968442B2 Accommodating intraocular lens
An intraocular lens includes a lens capsule expanding device and an optical portion. A front supporting portion makes contact with an inner surface of an anterior capsule. A rear supporting portion makes contact with an inner surface of a posterior capsule while facing the front supporting portion. A connecting portion connects the front supporting portion and the rear supporting portion so as to have a biasing force to separate the front supporting portion and the rear supporting portion. Due to the biasing force, the front supporting portion presses the inner surface of the anterior capsule and the rear supporting portion presses the inner surface of the posterior capsule. The optical portion changes the curvature of a central portion according to movement of the connecting portion that moves the front supporting portion and the rear supporting portion closer to or away from each other with movement of the lens capsule.
US09968438B2 Method of fabricating artificial electronic skin
High resolution active matrix nanowire circuits enable a flexible platform for artificial electronic skin having pressure sensing capability. Comb-like interdigitated nanostructures extending vertically from a pair of opposing, flexible assemblies facilitate pressure sensing via changes in resistance caused by varying the extent of contact among the interdigitated nanostructures. Electrically isolated arrays of vertically extending, electrically conductive nanowires or nanofins are formed from a doped, electrically conductive layer, each of the arrays being electrically connected to a transistor in an array of transistors. The nanowires or nanofins are interdigitated with further electrically conductive nanowires or nanofins mounted to a flexible handle.
US09968429B2 Systems and methods for delivering a medical implant to an anatomical location in a patient
In a general aspect, a delivery device for delivering a medical implant can include a handle, a shaft having a first curved portion and terminating in a conical tip at a distal end and a transitional portion coupling the shaft with the handle. The transitional portion can include a first substantially straight section, a second substantially straight section and an angled section disposed between the first and second substantially straight sections. The angled section can define an angle between the first substantially straight section and the second substantially straight section. The first substantially straight section can extend from the distal end of the handle and have an outside diameter greater than an outside diameter of a distal end of the second substantially straight section. The second substantially straight section can have a distal end axially adjacent to the proximal end of the shaft and have a diameter that decreases distally.
US09968427B2 Electric toothbrush, and transmission for an electric toothbrush
The transmission according to the invention for an electric toothbrush serves for the transmission and reforming of a rotational movement provided by an electric motor into a particularly careful and effective cleaning movement of a cleaning element. The ratio of the distance between the longitudinal mid-axis of an output shaft and the longitudinal mid-axis of a drive shaft of the transmission and of the distance between the longitudinal mid-axis of a shaft driving a cam of the transmission and the longitudinal mid-axis of the cam amounts to at least 10:1.
US09968426B2 Method for the production of an interdental cleaner
An interdental cleaner has a rod-shaped carrier formed of plastic, which has a structuring with structural elements radially protruding from the carrier on at least one section of an axial length thereof. The carrier is twisted in at least one part of the section having the structuring together with the structuring about a carrier longitudinal axis.
US09968421B2 Tooth positioner and vibrator combination
A tooth positioner is combined with a vibrational source, thus speeding orthodontic remodeling. In more detail, the device includes a tooth positioner shaped to closely fit a patient's dentition and apply a straightening force to at least one of said patient's teeth, the tooth positioner contacting labial, lingual and occlusal surfaces of said patient's dentition, the tooth positioner operably connected to a housing enclosing a power source operably connected to a vibratory source, the vibratory source being able to vibrate, thus vibrating the tooth positioner. Methods of using the positioner-vibrator combination are also disclosed.
US09968419B2 Method and oral appliance for improving air intake and reducing bruxism
Provided is a soft flexible oral appliance having protuberances that mimic naturally occurring dental Tori. An upper, palatial appliance and a lower, mandibular appliance may be used in conjunction or separately to alleviate a variety of disorders, improve facial tone, and increase physical performance. The appliances are lightweight, thin, and do not prohibit normal speech patterns when in use. Small protuberances are strategically molded along key surfaces of each appliance to stimulate nerves in the tongue and affect forward protrusion. Forward positioning of the tongue dilates the airways of the throat improving breathing while the use is sleeping, playing sports, or talking. It also reduces bruxing, or grinding of the teeth. A method is further provided, for adding protuberances to other types of oral appliances, thereby conferring some of the benefits listed above on appliances originally intended for other dental uses.
US09968418B1 Dental forceps with a post for extracting teeth
A dental forceps that include an elongated handle and a pair of tooth engaging members or jaws extending out of the one end of the handle and a post located in the handle with a disc at the top with a ball at the other end of the post. The post ball end inserts into the post ball holder to provide a stable support so that the dentist has leverage to extract the tooth straight out. The post disc and post ball provide the forceps with side-to-side and back-and-forth movement, thus allowing the forceps to align to the growth angle of the tooth to be extracted.
US09968408B1 Spinal balance assessment
The present application describes computer apparatus and software programs useful to the field of corrective spinal surgery. The apparatus and software implement and facilitate methods for assessing the degree of balance and alignment achieved through corrective measures applied to the spine prior to completing a surgical procedure. The apparatus and software facilitate pre-operative planning and virtual testing of the corrective measures to be applied. The apparatus and software further facilitate intra-operative reconciliation with the pre-operative plan prior to completing the surgery.
US09968407B2 Apparatus and method for collecting reusable material and cleaning surgical instruments
A system and method for cleaning instruments, which provides removal and collection of material from one or more surgical instruments. The cleaning apparatus may be a dry cleaning process or offered in conjunction with one or more fluids. In one embodiment, the cleaning apparatus continuously purges blood, bone and other debris quickly and may comprise a system for removing reusable material from the cleaning process for reuse.
US09968395B2 Systems and methods for treating the prostate
A vapor delivery system and method is provided that is adapted for treating prostate tissue. The vapor delivery system includes a vapor delivery needle configured to deliver condensable vapor energy to tissue. In one method, the vapor delivery system is advanced transurethrally into the patient to access the prostate tissue. The vapor delivery system is properly positioned by measuring and advancing the system based on a field-of-view of an endoscope or camera disposed within the system.
US09968393B2 Bending pin
A system for bending an implant includes a drill guide extending longitudinally from a proximal end to a distal end, the drill guide including a distal portion having a first threading extending therealong to engage a threading along an interior of a bone fixation element receiving hole of an implant and a proximal portion having a second threading extending therealong and a bending pin extending longitudinally from a proximal end to a distal end including a recess extending proximally therefrom, the recess sized and shaped to receive the proximal portion of the drill guide and including a corresponding threading therealong for engaging the second threading.
US09968384B2 Medical screw driver, shank for medical screw driver and method of introducing pedicle screws
A medical screw driver includes a shank having a coupling for a handling member for applying torque to the shank. A screw driver portion can be inserted in a pedicle screw head and transmit torque to the screw head. A sleeve is rotatable about the shank and includes a male thread for coupling to a female thread formed at the pedicle screw head. The sleeve has a first sleeve portion having a first engaging portion and a second sleeve portion having a second engaging portion. The first and second engaging portions engage so that the second sleeve portion can transmit torque to the first sleeve portion, and so that the second sleeve portion can be disengaged from the first sleeve portion and drawn off the shank without having to release the first sleeve portion from the pedicle screw head.
US09968377B2 Spinal rods formed from polymer and hybrid materials and growth rod distraction system including same
A growth rod distraction system a domino having first and second bores provided therein. First and second spinal rods are respectively disposed within the first and second bores for movement relative to the domino. First and second spur gears are disposed within the domino and respectively cooperate with the first and second growth rods such that rotation of the spur gears causes axial movements of the growth rods relative to the domino. The spinal rods may be formed either from a flexible polymer material (such as a PEEK, carbon fiber PEEK, PEAK, or similar medical grade polymer material) or a hybrid combination of such flexible polymer material and a metallic material (such as nitinol or similar medical grade metallic material). The spinal rods can also be used for fusion or non-fusion surgery of the spine to stabilize two or more vertebrae.
US09968373B1 Handles for needle assemblies
An impact or extension handle for a needle assembly such as a jamshidi needle can include an attachment portion and a handle portion. The impact or extension handle can also include an impact strikeplate. The attachment portion is configured to couple to the jamshidi needle. A user can use the impact or extension handle to manipulate the position or angle of the needle assembly. A user can tap a mallet or similar instrument on the impact strikeplate to drive the needle assembly into a target location in a patient's body. The impact or extension handle can allow the user to hold his or her hands out of the way of equipment used during the procedure and away from potentially harmful radiation from imaging equipment used during the procedure.
US09968365B2 Stabilizing microfracture device
A microfracture device comprising a guide shaft having a proximal end and a distal end and defining an internal passage between the proximal and distal ends, the distal end having a curved tip, a stabilizing portion disposed along an outer surface of the guide shaft, at least a portion of the stabilizing portion being wider than the guide shaft, and a flexible element movably positioned within the internal passage of the guide shaft, the flexible element having a distal tip configured for driving into bone.
US09968364B2 Orthopaedic cutting block
A method of forming a bone cutting block includes: forming a plurality of saw slot plates and two side plates, the plurality of saw slot plates each including a plurality of ends opposing one another, each of the plurality of ends including a locating feature, the side plates including a plurality of locating features; and supporting the plurality of saw slot plates using the side plates, each locating feature of the plurality of saw slot plates being connected with a respective one of the plurality of locating features of the side plates and the side plates thereby opposing one another, the plurality of saw slot plates defining at least one slot therebetween which is configured for receiving a bone saw blade therethrough to make a predefined cut in a bone.
US09968361B2 Clip applying apparatus with angled jaw
A clip applying apparatus is provided which includes a jaw mechanism having a stationary jaw and a movable jaw. The movable jaw is supported on or formed integrally with the distal end of a crimping member which is movably supported within a body portion of the apparatus. The stationary jaw defines a longitudinal axis which forms an angle θ of between about 15 degrees and about 15 degrees and about 75 degrees in relation to a longitudinal axis of the body portion. In another embodiment, the stationary jaw includes a clip receiving channel which is configured to at least partially receive a surgical clip. In one embodiment, the distal end of the stationary jaw includes a stop member which is positioned to engage the distal end of the stationary jaw includes a stop member which is positioned to engage the distal end of a leg of a surgical clip to prevent the surgical clip from being pushed from the stationary jaw during operation of the apparatus and the movable jaw includes a distally located crimping surface and a head portion defining a recessed channel configured to receive a portion of a surgical clip supported on the stationary jaw. In yet another embodiment, the crimping surface defines an acute angle β in relation to the longitudinal axis of the body portion, and in one embodiment, angle β is substantially the same as angle θ.
US09968359B2 Temporary embolic protection device and medical procedure for delivery thereof
A medical procedure for positioning an embolic protection device effectively prevents material from entering with blood flow into side branch vessels of the aortic arch. The protection unit is permanently attached to a transvascular delivery unit at a connection point at a support frame that is at least partly arranged at a periphery of a selectively permeable unit. In an expanded state of the device, the connection point is enclosed by the support member or arranged at said support member.
US09968358B2 Implant delivery system
In one embodiment, the present invention relates to a mechanically releasable delivery system. More specifically, this embodiment includes an implantable device secured by tether at a distal end of the delivery system. The tether is fixed to the implantable device and looped around a selectively slidable mandrel. When the mandrel is retracted to expose its distal end, the looped tether slides off the mandrel, freeing the implantable device. Alternately, the tether can be fixed to the delivery system, wrapped around a portion of the implantable device and looped on to the slidable mandrel. Preferably, movement of the mandrel is controlled by an actuation control on the handle of the delivery system, allowing the user to selectively release the implantable device during a medical procedure.
US09968356B2 Surgical instrument drive systems
A surgical instrument for stapling the tissue of a patient is disclosed. The surgical instrument comprises a shaft and an end effector. The end effector comprises a staple cartridge body including staple cavities defined therein, staples removably positioned in the staple cavities, an anvil configured to deform the staples, and a knife configured to cut tissue positioned intermediate the staple cartridge body and the anvil. The surgical instrument further comprises a staple drive system configured to eject the staples from the staple cavities and a knife drive system configured to move the knife relative to the staple cartridge body independently of the staple drive system.
US09968355B2 Surgical instruments with articulatable end effectors and improved firing beam support arrangements
A surgical instrument that includes a surgical end effector that is coupled to a shaft assembly by an articulation joint. A flexible firing beam extends through the articulation joint to interface with a firing member in the surgical end effector to apply a firing motion thereto. In at least one form, a pair of firing beam support members flank the flexible firing beam across the articulation joint. The firing beam support members are movably coupled together to prevent lateral movement away from each other in directions transverse to a shaft axis that is defined by the shaft assembly while permitting the firing beam support members to move axially relative to each other.
US09968354B2 Surgical staples and methods for making the same
A surgical staple and staple cartridge for removably storing the surgical staple. The staple can be formed and/or stamped from a sheet of material. The staple can include a base and staple legs extending from the base. The base can be non-linear and/or laterally contoured intermediate the staple legs.
US09968349B2 System and method for securing tissue to bone
Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow the use of bone anchors to secure tissue to bone.
US09968343B2 Minimally invasive surgical instrument having a bent shaft
The present invention relates to a minimally invasive surgical instrument having a bent shaft, and more particularly to a minimally invasive surgical instrument in which at least a part of a shaft includes a bend. According to one aspect of the invention, there is provided a minimally invasive surgical instrument comprising: a shaft; an end effector connected to one end of the shaft; a joint unit interposed between the shaft and the end effector; and a plurality of wires connected to the joint unit to enable the end effector to carry out joint motion, wherein the shaft comprises at least one bend, and the at least one bend may transmit therein force to operate the end effector in a roll direction, independently of the shaft.The present invention relates to a minimally invasive surgical instrument having a bent shaft, and more particularly, to a minimally invasive surgical instrument in which at least a portion of a shaft is curved. A minimally invasive surgical instrument according to one embodiment of the present invention comprises: a shaft; an end effector connected to one end of the shaft; an articulation unit interposed between the shaft and the end effector; and a plurality of wires connected to the articulation unit so as to enable the end effector to move in an articulating manner. The shaft has at least one curve, and said at least one curve is capable of independently transmitting force to the inside of the end effector such that the end effector may operate in a rolling direction.
US09968342B2 Handle for surgical instruments
A handle for surgical instruments that has a “wishbone” configuration. In one embodiment, the instrument is provided with a ratchet mechanism allows two operating handles to be locked in a predetermined position (for example, when the surgical instrument that is maneuvered is in use) or to move relative to each other when the ratchet is partially or fully released (for example, when the surgical instrument that is maneuvered is not in use). In another embodiment, the instrument is provided with a rotary gear mechanism.
US09968337B2 Coring tissue biopsy needle and method of use
Biopsy devices and methods are provided for collecting a sufficiently-sized tissue sample from a region at a known distance by boring into the sample region using simultaneous axial and rotational movement and providing a reduced risk of: over-passing or under-passing the sample sought, injury and trauma to the surrounding tissue area, having to stick the patient more than once, sample contamination, and the user's exposure to sharps.
US09968336B2 Liquid sampler, kit of parts, and method for assembly
A device for capturing a predetermined volume of a predefined portion (e.g. first void) of a liquid flow, comprises an inlet, an outlet, and a guide with an element displaceable in a first position for capturing the first liquid portion in a reservoir, and in a second position for blocking access to the reservoir, and for passing the liquid to the outlet. The displaceable element moves in transverse direction to the liquid flow, and has lifting means. The element may be substantially flat, or tubular with an elliptical cross section. A kit of parts and a method of assembly are also claimed.
US09968323B2 X-ray computed tomography apparatus
An X-ray computed tomography apparatus according to an embodiment includes an X-ray detector, a data-acquisition module and a reconstruction module. In the X-ray detector, a plurality of X-ray detection elements are arranged in a channel direction and a column direction. The data-acquisition module includes a plurality of data-acquisition circuits and a plurality of output modules. A plurality of systems of at least the data-acquisition circuits among the X-ray detection elements and the data-acquisition circuits are disposed in parallel per element of the X-ray detection elements in a center vicinity. Each of the output modules outputs digital data obtained via the data-acquisition circuits. The reconstruction module reconstructs a medical image, based on the output digital data.
US09968320B2 X-ray diagnostic apparatus
According to one embodiment, an X-ray diagnostic apparatus includes an X-ray tube that generates X-rays, an X-ray detector that detects X-rays generated from the X-ray tube and transmitted through an object, a supporting mechanism supports the X-ray tube and the X-ray detector in directions to face each other, a display displays an X-ray image concerning the object based on an output from the X-ray detector, position specifying circuitry specifies a position of the face of a user who is visually recognizing the display, and moving circuitry moves the supporting mechanism to an imaging position corresponding to the specified position of the face of the user.
US09968318B2 Estimating apparatus, X-ray diagnosis apparatus, and estimating method
An estimating apparatus according to an embodiment includes specifying circuitry, deriving circuitry, and display control circuitry. The specifying circuitry specifies a region of a subject irradiated with X-rays emitted from an X-ray tube of an X-ray CT apparatus on a human body model schematically representing the subject. The deriving circuitry assumes the human body model to be at a position where the subject is arranged in radiography performed by the X-ray CT apparatus and derives an exposure dose of the X-rays on a surface of the region specified by the specifying circuitry on the human body model based on irradiation conditions in the radiography. The display control circuitry displays, on a display, information in which the exposure dose derived by the deriving circuitry is associated with the region on the human body model specified by the specifying circuitry.
US09968312B2 Floor mat radiation attenuation shield
A system attenuates scatter radiation during a radiological procedure. The radiological procedure using a radiation machine including an emitter, a receiver, a base, and a table for a patient. The base is supported by a floor. The system includes a barrier formed of a radiation attenuation material and positioned over an area on the floor. The barrier is comprised of an elastomeric material and disposed beneath the table. The barrier on the floor can reduce substantial amounts of scatter radiation.
US09968309B2 Method and a correction system for correcting tracer-uptake measurements
This invention relates to a method and a correction system for correcting tracer-uptake measurements for patient specific variations in the tracer-uptake. Input data are received about the patient and subsequently it is determining whether the received input data include tracer-impact data that impact the tracer-uptake measurements for the patient. In case the tracer-impact data are included in the input data a comparing is performed where the tracer-impact data are compared with pre-stored reference data that have associated thereto a correction indicator indicating an amount of deviation of the tracer-uptake measurement due to the tracer-uptake dependent data. The correction indicator of the pre-stored reference data that match with the tracer-impact data is then used to correct the tracer-uptake measurements for the patient.
US09968303B2 System and method of adaptive interpretation of ECG waveforms
A cluster database includes existing ECG datasets organized into clusters, wherein each existing ECG dataset includes an existing ECG waveform with at least one corresponding existing feature and existing interpretation. Each cluster is comprised of existing ECG datasets having a common existing feature. The cluster training module is executable by the processor to receive a new ECG waveform and a feature extracted from the new ECG waveform. The cluster training module then selects a cluster interpretation module based on the feature, wherein the cluster interpretation module is trained on one of the clusters from the cluster database. The cluster training module processes the new ECG waveform and/or the feature to provide a cluster interpretation output. The cluster interpretation output is then displayed on the user interface, and the cluster training module receives clinician input via the user interface accepting or rejecting the cluster interpretation output.
US09968296B2 Wearable socio-biosensor device
A wearable socio-biosensor device can include a plurality of sensors to detect bio-behavioral data of a subject, social data related to a proximity of the subject to other persons wearing socio-biosensor devices and bio-behavioral data measured during the time the subject is in close proximity to other persons, and environmental data related to the subject's environment. The socio-biosensor device can also include a body portion that includes: a non-transitory memory to store the bio-behavioral data, the social data, and the environmental data; a wireless transceiver to communicate with another device based on at least one of the bio-behavioral data, the social data, and the environmental data; and a rechargeable battery. The socio-biosensor device can also include an attachment mechanism that facilitates attachment of the body portion to the subject (e.g., attached to the subject's wrist). At least one of the plurality of sensors can be embodied in the attachment mechanism.
US09968288B2 Systems and methods for predicting seizures
The present invention provides for a computer system including at least one server having software stored on a non-transient computer readable medium; where, upon execution of the software, the at least one server is at least configured to: i) receiving physiological data representative of a first physiological measurement of at least one physiological characteristic of an epileptic user; ii) receiving physiological data representative of a second physiological measurement of at least one physiological characteristic of the epileptic user; iii) comparing the first physiological measurement of the epileptic user to the second physiological measurement of the epileptic user; iv) based on the comparing, determining that a difference between the first physiological measurement of the epileptic user and the second physiological measurement is: a) higher than a predetermined threshold value, or b) smaller than the predetermined threshold value; and v) generating at least one alert; vi) transmitting the at least one alert.
US09968281B2 Breath condensate collector
A breath condensate collector (10) comprising a chamber having a breath inlet port (14) and an outlet port (16); a sample collector, adapted to receive breath from the chamber outlet and having air exhaust means; cooling means (112) to promote in use condensation of vapor from breath entering the sample collector and where collector comprises a partially lidded dish (110).
US09968278B2 Medical image measuring apparatus, method, and medium
A medical image measuring apparatus includes a tissue information label assigning unit that assigns each point of a medical image with a tissue information label representing tissue information each point belongs, a measuring unit that performs measurement in the medical image, and a measurement subject label assigning unit that determines, based on a tissue information label assigned to a measurement point or a point within a region of interest used for the measurement, a measurement subject label representing a measurement subject and assigns the label to a result of the measurement.
US09968275B2 Non-invasive method and system for characterizing cardiovascular systems
The present disclosure uses physiological data, ECG signals as an example, to evaluate cardiac structure and function in mammals. Two approaches are presented, e.g., a model-based analysis and a space-time analysis. The first method uses a modified Matching Pursuit (MMP) algorithm to find a noiseless model of the ECG data that is sparse and does not assume periodicity of the signal. After the model is derived, various metrics and subspaces are extracted to image and characterize cardiovascular tissues using complex-sub-harmonic-frequencies (CSF) quasi-periodic and other mathematical methods. In the second method, space-time domain is divided into a number of regions, the density of the ECG signal is computed in each region and inputted into a learning algorithm to image and characterize the tissues.
US09968273B2 ECG waveform detecting apparatus and imaging apparatus
According to one embodiment, an ECG waveform detecting apparatus includes an input circuit and processing circuitry. The input circuit receives an ECG signal. The processing circuitry performs first detection of a specific waveform included in the ECG signal, performs update processing of a detection parameter for detecting the specific waveform based on a part of the specific waveform or result of the first detection, performs second detection of the specific waveform from the ECG signal by using the detection parameter after the update processing, and generates a synchronization signal based on information on the second detection.
US09968272B2 Device for detecting electric potentials
A device detects electric potentials with measuring inputs (7) for connection to measuring electrodes (9), which can be placed on the body of a patient (3). Measuring amplifiers (Op1, . . . , OpN) have a first and a second input as well as an output (11). A summing unit (13, 23) is connected to the outputs of the measuring amplifiers and sends a signal proportional to a mean value of the signals of the outputs of the measuring amplifiers to an output (15, 17) of the summing unit. Each of the measuring inputs is connected to a first input of a measuring amplifier. The second input of each measuring amplifier is connected to the output (17) of the summing unit. A potential output (19) connects to an electrode and to an output of a further amplifier Opc), with an input connected to the output (15) of the summing unit.
US09968265B2 Method and system for characterizing cardiovascular systems from single channel data
Methods to identify and risk stratify disease states, cardiac structural defects, functional cardiac deficiencies induced by teratogens and other toxic agents, pathological substrates, conduction delays and defects, and ejection fraction using single channel biological data obtained from the subject. A modified Matching Pursuit (MP) algorithm may be used to find a noiseless model of the data that is sparse and does not assume periodicity of the signal. After the model is derived, various metrics and subspaces are extracted to characterize the cardiac system. In another method, space-time domain is divided into a number of regions (which is largely determined by the signal length), the density of the signal is computed in each region and input to a learning algorithm to associate them to the desired cardiac dysfunction indicator target.
US09968261B2 Apparatus and method for providing diffuse spectroscopy co-registered with optical frequency domain imaging
An apparatus can be provided according to certain exemplary embodiments. For example, the apparatus can include a waveguiding first arrangement providing at least one electromagnetic radiation. A configuration can be provided that receives and splits the at least one electromagnetic radiation into a first radiation and a second radiation. The apparatus can further include a waveguiding second arrangement which has a first waveguide and a second waveguide, whereas the first waveguide receives the first radiation, and the second waveguide receives the second radiation. The first arrangement, the second arrangement and the configuration can be housed in a probe.
US09968258B2 Imaging fluorescence or luminescence lifetime
Devices for use in fluorescence or luminescence lifetime imaging include a chip featuring an imaging region that includes a photodetector for receiving optical signals, and a time-to-digital converter for providing digital phase output based on the received optical signals.
US09968249B2 Endocranial endoscope
An endoscope particularly suited for endocranial procedures and a method of using the endoscope. In some examples the endoscope is rigid except for a bend/tilt portion near a distal end of a rigid tube that is inserted in a patient's cranium, which distal end is controlled in a degree and direction of tilt with a finger operated controller at the endoscope's handle. Some examples use telescoping tubes that allow customizing the endoscope size for specific procedures. A distal portion of the endoscope can be disposable, supplied in a sterile package for a single procedure, thus taking into account contamination dangers that are particularly high for intracranial and certain other interventions and the fact that it can be difficult or impossible to effectively autoclave heat-sensitive components of certain endoscopes or effectively sterilize them using other techniques.
US09968247B2 Cleaning device for an endoscopic device
A cleaning device for use with an endoscope. The device includes an elongated and flexible base and a set of discs axially spaced along the base. Each disc is positioned along the base at a center point of the disc. The size and spacing of the discs may vary within the set of discs.
US09968239B2 Remote controller for balloon controlling device and endoscope system
A remote controller includes a first balloon operation section, a second balloon operation section, a first balloon state display section, and a second balloon state display section. Each of the first and second balloon operation sections performs a pressing operation to swell or contract a balloon. Each of the first and second balloon state display sections has a swollen-state display portion and a contracted-state display portion. The swollen-state display portion is disposed along an outer circumference of each of the first and second balloon operation sections, such that the swollen-state display portion and each of the first and second balloon operation sections are coaxial with each other. The contracted-state display portion is disposed inside each of the first and second balloon operation sections, such that the contracted-state display portion and each of the first and second balloon operation sections are coaxial with each other.
US09968236B2 Dishwasher appliance and a method for operating the same
The present subject matter provides a method for operating a dishwasher appliance. The method includes finely filtering wash fluid with a fine filtration medium via cross-flow filtration and coarsely filtering wash fluid with a coarse filtration medium via dead-end filtration. The finely filtered wash fluid is directed to a spray assembly of the dishwasher appliance. A related dishwasher appliance is also provided.
US09968235B2 Floor cleaning machine including a sanitize mode
A floor cleaning machine for cleaning a surface includes a body, a distribution nozzle supported by the body, a supply tank assembly coupled to the body in fluid communication with the distribution nozzle, a suction nozzle supported by the body, and a suction source in fluid communication with the suction nozzle. The suction source is operable to draw fluid and dirt from the surface through the suction nozzle. The floor cleaning machine also includes a recovery tank coupled to the body in fluid communication with the suction source to receive and store fluid and dirt drawn through the suction nozzle. The floor cleaning machine is operable in a first mode to wash the surface and is operable in a second mode to sanitize the surface.
US09968233B2 Automatically driven cleaning device
A device for cleaning or processing a surface, wherein the device has a light source for illuminating the surface with light and an optical detection device for detecting the light reflected by the surface. In addition, the invention relates to a method for operating a device according to the invention. To create a device for cleaning or processing a surface and a method of the type in question, which differentiates various surfaces with a better resolution than that in the prior art, it is proposed that the optical detection device has at least one filter element and at least one sensor element, which are arranged and designed to detect the light reflected from the surface with respect to at least four different spectral ranges.
US09968230B2 Seat-type air extracting suction apparatus to aid bowel movement
Disclosed is a seat-type air-extracting suction apparatus to aid bowel movement having a main body (10), a support frame (20), a vacuum motor (30) and a pressure regulation valve (40), wherein the main body (10) is provided with a loading housing (11), a seat cushion (13) and an extraction box (12), the loading housing (11) has a first through hole (111), the seat cushion (13) is provided on the loading housing (11) and is formed with a guidance hole (131), the guidance hole (131) is aligned with the first through hole (111) of the loading housing (11), the extraction box (12) penetrates through and is provided in the loading housing (11), and an internal space of the extraction box (12) corresponds to the first through hole (111). The support frame (20) is provided on the outside of the main body (10) and is provided with a starting switch (22). The vacuum motor (30) is connected to the main body (10) and is used for extracting air to reduce the pressure inside the loading housing (11), a negative pressure effect being created when extracting air via the vacuum motor (30), aiding the bowel movement of a user. The pressure regulation valve (40) is able to adjust the pressure inside the loading housing (11) to meet the comfort level of the user.
US09968212B1 Tension rod and room divider assembly
An improved tension rod having a first thin-wall metal tube, a plastic bushing inserted inside the first metal tube, a second thin-wall metal tube the second metal tube set partially inside the first metal tube, a helically-wound metal spring with an eyelet on one end and a two closed coils on the other end, the metal spring retained inside the first metal tube by a first diameter metal rivet and in the second metal tube by a second diameter metal rivet, the second metal tube having an end cap on the end opposite the first metal tube, a third metal tube being an extension tube connected to the first metal tube by an expansion clamp located between the first metal tube and the extension tube, the extension tube having an end cap located opposite the first metal tube.
US09968210B2 Composite structure of fixable food container
A composite structure of a fixable food container is disclosed. The composite structure comprises a plurality of food containers and a fixing disc. A first connecting portion is formed on the bottom of the food container. The fixing disc is used for fixing on a surface. A second connecting portion is formed on the top of the fixing disc for connecting with the first connecting portion and a hole is formed at the center of the fixing disc. The composite structure of the fixable food container has numerous advantages such as improved non-slip capability, stability, and positioning and has compatibility that allows the fixing disc to connect with different kinds of food containers.
US09968205B1 Infant sleeping bag, blanket and sheet
An apparatus for improved sleep made up of a mattress, and a sleep aid, on a first end of the mattress the sleep aid being a partially fitted sheet, the fitted sheet tucked into and secured onto a side of the mattress, and on a second end of the mattress the sleep aid being a blanket, the blanket attached to the fitted sheet and the blanket being large enough to be folded over an infant, the fitted sheet having hook and loop fasteners and the blanket having matable hook and loop fasteners situated on the blanket opposite the fitted sheet, such that when the blanket is folded over and the hook and loop fasteners are mated a pocket capable of containing an infant is formed.
US09968204B2 Child motion apparatus
A child motion apparatus includes an apparatus base, a movable carrier, a seat mount, a motion mechanism, and a seat assembly. The movable carrier is movably disposed on the apparatus base along a sliding direction. The seat mount is rotatably connected to the movable carrier about a rotation axis perpendicular to the sliding direction. The motion mechanism includes a sliding mechanism and a rotating mechanism. The sliding mechanism connects the movable carrier and the apparatus base for sliding the movable carrier relative to the apparatus base along the sliding direction. The rotating mechanism is disposed on the movable carrier and connected to the seat mount for rotating the seat mount about the rotation axis. The seat assembly is detachably connected to the seat mount, so that the seat assembly slides and rotates together with the seat mount.
US09968188B1 Locking base for tablet stand
A lockable electronic tablet stand is described that allows rotation and fixes the tablet stand in a locked relation. The stand includes a base that allows the tablet stand to rotate about the base while cords extend through a center of the base.
US09968186B2 Adjustable keyboard tray and mouse pad
An adjustable keyboard tray with an adjustable mouse pad is disclosed. A connection mechanism of the keyboard tray provides: vertical height adjustment of the keyboard tray relative to an object to which it is connected; horizontal translational adjustment of the keyboard tray relative to the object; swivel movement of the keyboard tray about a vertical axis; and adjustable typing angle of the keyboard tray relative to a horizontal axis. A connection mechanism of the mouse pad is configured to: permit the mouse pad to be connected to either side of the keyboard tray; provide for angular adjustment of the mouse pad relative to the keyboard tray; and provide for height adjustment of the mouse pad relative to the keyboard tray. In this manner, the fully articulated keyboard tray may be arranged at an angle relative to horizontal, and the mouse pad may simultaneously be arranged in a horizontal position.
US09968185B2 Sturdy lightweight table base and method
A sturdy lightweight table support system offers advantages of self-squaring, sturdy design, a low unassembled volume combined with simple parts that enable easy assembly, a system that enables user specification of table size that will result in easily prepared components thus all but eliminating stocks of different sized components, and sturdy lockable height adjustments. The self-squaring is achieved with a corner bracket system that uses a corner bracket that is inset with respect to a cross member within which it is mounted so that bolted assembly will result in a large, even pressure about the butt end of the cross member against the post that is extremely resistive to angular displacement of the cross member with respect to the post in any direction.
US09968183B1 Fingernail brush having angularly adjustable bristles
A fingernail brush that includes bristles that are angularly adjustable by a user of the brush. In one embodiment, the fingernail brush includes a housing and a bristle assembly having a bristle support and at least one row of bristles. The bristle assembly is rotatably coupled to the housing so that a user can rotate the bristles to a desired relative bristle angle. In some embodiments, the bristles are present in a bristle channel formed as a recess in a face of the housing. The angular adjustability of the bristles allows a user to set the bristles to a relative bristle angle appropriate for the way the user intends to orient their fingertips relative to the fingernail brush. In some embodiments, a fingernail brush of the present disclosure may include one or more vibration generators that cause bristles to vibrate at a sonic frequency, an ultrasonic frequency, or both, to enhance cleaning efficacy.
US09968175B2 Applicator for a liquid or viscous cosmetic and the associated packaging assembly thereof
An applicator for a liquid or viscous cosmetic and packaging assembly thereof. The applicator extends in a longitudinal extension direction (X) and comprises a distal end and a proximal end. The applicator comprises an end piece, at the proximal end, which can be attached to a rod of an applicator assembly, a spatula at the distal end, and a base which connects the end piece and the spatula. The end piece, the base, and the spatula being a single piece made of a polymer material. The spatula comprises at least two tongues, each having an end connected to a solid portion of the spatula and an opposite end, and at least two applicator tabs formed in the extension of each tongue in the region of the opposite end, each tab having a free end which forms the distal end of the applicator.
US09968171B2 Multifunctional hair treatment device
A multifunctional hair treatment device. A handpiece in the shape of a glove has nozzles on fingers thereof. A device body draws in and heats ambient air, thereby creating hot wind. A blower tube connects the nozzles of the handpiece to the device body to supply hot wind created in the device body to the nozzles of the handpiece. A user can dry and style hair using the handpiece worn on his or her hand.
US09968170B2 Suitcase, especially a pilot suitcase
A suitcase made from hard shell material, preferably a pilot suitcase, including a lower suitcase portion which is open at the top, with a front panel, a rear panel and two side end panels, and a bottom panel, and a hinged lid for closing, wherein a telescopic handle can be pulled out in an upwards direction is arranged on the rear panel of the lower suitcase portion for pulling or pushing the suitcase, the lid having a narrow stationary lid element which extends along the entire length of the lower suitcase portion along the rear panel and has an opening in the middle of the length, through which opening the telescopic handle can be pulled out, and, next to the opening for the telescopic handle, the lid having a hinge which connects the stationary lid element to a fold-down wide lid element.
US09968160B2 Sole assembly for an article of footwear with bowed spring plate
A sole assembly for an article of footwear has a curved spring plate that stores and releases spring energy to aid in forward propulsion. The curved spring plate has a center portion and opposite end portions extending from the center portion. A retaining member is secured to the end portions such that the retaining member spans across and bows the center portion. Flexing of the spring plate stores spring energy in the spring plate that urges the center portion to unflex and release the spring energy.
US09968157B2 Sole for a shoe
Improved soles for shoes, in particular sports shoes, are described. A sole for a shoe, in particular a sports shoe, is provided that includes a midsole with randomly arranged particles of an expanded material. The sole further includes an element having a higher deformation stiffness in at least one direction than the expanded material. The material of the midsole at least partially surrounds the element.
US09968154B2 Protective equipment having frangible energy absorbing elements
A protective helmet having a protective shell with an interior surface and an exterior surface. A padding layer is affixed to the interior surface. The padding layer comprises a compliant material and a frangible material, such as glass foam. At least the frangible material is enclosed in a container. A detection circuit detects compromise of the frangible material, and outputs an indicator in the event the compromise is detected. The detection circuit may include a frangible wire configured to break in the event the frangible material is compromised. The indicator may include an LED, and/or radio-frequency signals. The radio-frequency signal may include an identifier for the helmet. The padding layer may include a plurality of pads each containing compliant material and frangible material. The plurality of pads may include one or more fasteners for releaseably affixing the pads to the interior surface of the protective shell.
US09968150B2 Hair extension
What is claimed is an natural hair extension. The hair extension is formed with a foundation of an elastic mesh into which wefts of natural hair are sewn. The elastic may also be covered by a ribbon to prevent irritation of the scalp.
US09968149B2 Garment formed with extensible garment fabric
A garment comprising an extensible garment fabric having an edge fixed in length by a relatively inextensible tape or cord, the tape or cord being made from a material which can be eliminated or made extensible by subsequent processing; and an extensible waistband, the edge of the garment fabric fixed by the tape or cord being attached to the waistband.
US09968148B2 Nursing cover-up
In one embodiment, a nursing cover is constructed of a flexible cover body that is configured to cover a mother's front, particularly areas exposed while nursing a baby. For convenience of reference, the cover body can be described in terms of a top end, a bottom end and two sides. A track is coupled to the top end of the cover, and at least one clip is slidingly engaged with the track to permit the clip to slide along the track. In this way, not only does the cover provide privacy protection to a nursing mother, but the cover also includes a slidable clip that can serve a variety of functions.
US09968146B2 Guard accessory for pants
Disclosed herein is a protective guard accessory for protecting the cuff of a pant leg. In a version of the invention, the clothing accessory generally comprises a cuff protection sleeve comprising an annular wall portion with an upper enlarged portion and an inwardly curved bottom lip defining a circular channel. The circular channel adapted to receive a respective bottom cuff of the pants. In addition, an inner fastening ring is provided comprising an external annular channel configured to couple with the upper enlarged portion of the cuff protection sleeve. Wherein, while in use, the fabric of the pants is pinched or sandwiched between the top enlarged portion of the cuff protection sleeve and the inner fastening ring while simultaneously engaging the cuff within the circular channel. Thereby, engaging the clothing accessory with the lower end portion and bottom cuff of the respective pant leg and providing a barrier between the pant leg and respective shoe.
US09968139B2 Hidden control waistband garment
A lower body garment with shaping benefits is provided. The lower body garment may comprise an outer garment and a control panel inside the outer garment, such that the control panel is not visible from the outside of the outer garment. The control panel may have a rectangular shape and line a full circumference of an interior waist of the outer garment. Further, the control panel may be anchored to the outer garment at a top edge seam of the outer garment. In certain aspects, the lower body garment may be a legging, pant or skirt.
US09968128B2 Waterpipe and portions thereof or accessories therefor
A waterpipe arrangement that, in at least some configurations, is used with a water-based flavored substance instead of tobacco or other substances. In some configurations, the perforated foil has perforations in an annular arrangement configured to reduce, minimize or prevent coal ash from being introduced into the vapor consumed by the user. In some configurations, the consumable vapor-producing substance is in the form of a gel and can be provided in individual packaging. The individual packaging can be configured for placement directly into a receptacle of the bowl of the waterpipe. In some configurations, a single-use or disposable bowl is provided containing a consumable vapor-producing substance. The present disclosure also involves a pre-perforated foil or screen or a tool for perforating a foil.
US09968124B2 Freeze-dried, aerated fruit or vegetable compositions and methods of making thereof
The present invention comprises a freeze-dried, aerated fruit or vegetable composition comprising a fruit or vegetable ingredient and an emulsifier and methods of making thereof.
US09968116B2 Application of beta zeolite as multi-toxin binder in animal feed and related methods
The present invention relates to the application of beta zeolite in animal feed as a toxin binder. The beta zeolites, which contain 12 membered ring systems with Bronsted and Lewis acidic sites, have high binding efficacy against common toxins present in animal feed. This study aimed to evaluate the binding efficacy of the disclosed H beta zeolite (HBZ) has high binding efficiecy against major mycotoxins such as aflatoxin B1, ochratoxin A (OTA), zearalenone, mycophenolic acid, cyclopiazonic acid, Fumonisin B1, T-2 and patulin.
US09968107B2 Methods of making cheese products including artificial eyes
Food products including artificial eyes or eye voids interspersed throughout the product are provided by forming a visco-elastic mass of the food product and combining pieces of solidified carbon dioxide with the visco-elastic mass. The solidified carbon dioxide sublimes throughout the visco-elastic mass and forms carbon dioxide gas. The carbon dioxide gas expands and forms eye voids nearly instantaneously and the fully formed eye voids are provided in the food product in a matter of hours. In addition, gaseous carbon dioxide stored under pressure, such as through encapsulation or in a pressurized vessel, is combined with a visco-elastic mass and the released carbon dioxide gas expands and forms eye voids defined within the visco-elastic mass.
US09968099B2 Formulation comprising a particulate calcium silicate and clonostachys rosea for treating plants
A powder plant treatment formulation for application to plants by insect vectoring includes: a plant treatment agent; a stabilizing agent bonded to the plant treatment agent for stabilizing the plant treatment agent; a moisture absorption agent for absorbing moisture from the formulation; an attracting agent for attracting the formulation to plants; and a diluent.
US09968098B2 Synergistic Bacillus thuringiensis subsp. aizawai, Bacillus thuringiensis subsp. kurstaki and cyantraniliprole mixtures for diamondback moth, beet armyworm, southwestern corn borer, and corn earworm
The present invention generally relates to the use of synergistic amounts of Bacillus thuringiensis subsp. aizawai, Bacillus thuringiensis subsp. kurstaki and cyantraniliprole for the control of diamondback moth, beet armyworm, southwestern corn borer, and corn earworm wherein the ratio of Bacillus thuringiensis subsp. kurstaki to Bacillus thuringiensis subsp. aizawai is from about 1:0.47 to about 1:0.92, and the ratio of the total amount of Bacillus thuringiensis to cyantraniliprole is from about 1:0.025 to about 1:150.
US09968085B2 Uses of thaxtomin and thaxtomin compositions as herbicides
Disclosed herein is a bacterial secondary metabolite, thaxtomin and another herbicide as an effective herbicide combination on broadleaved, sedge and grass weeds.
US09968082B2 Organ transporter with tilt and/or shock sensing
A method of perfusing an organ or tissue includes perfusing the organ or tissue with a perfusion apparatus; detecting a condition representing at least one of an attitude of the perfusion apparatus or at least one shock experienced by the perfusion apparatus; and altering perfusion based upon the detected condition and/or recording the detected condition.
US09968081B2 Hunting decoy apparatus for luring wild game
A hunting decoy apparatus, wherein the decoy exhibits lifelike movements controlled mechanically by a user. The apparatus comprises an outer sleeve member and a movable slidable member slidably engaged within the outer sleeve member. The outer sleeve member attaches to the ground. The decoy stand is inserted into the movable sliding member and extends perpendicular from the outer sleeve member in an upward direction with a decoy on top. The distal ends of the slidable inner sleeve member and the outer sleeve member are connected by an extension limiting biasing element such as a spring or elastic cord. A tether is attachable to the proximal end of the movable slidable member. To activate movement of the decoy, the tether is pulled and released by the user causing the decoy and decoy stand to move within the slot forward and backwards. Small tugs on the tether by the user causes the decoy to move in lifelike movements creating the appearance the decoy is bobbing and pecking like a wild bird.
US09968078B2 Smart fishing rod and system for detecting fishing related events
Described is an apparatus and system for detecting fishing related events and providing notifications to a fisher regarding those events. When a fishing related event, such as a fish on line event occurs, it results in a fishing rod flexing or moving in particular directions. The described implementations include sensors located on or in the fishing rod that provide position data that is utilized to monitor a movement of the fishing rod and determine a type of fishing related event that has occurred.
US09968072B2 Measuring device useful for animal weight management
The invention provides measuring devices for managing the weight of animals and methods of using the measuring devices. In a general aspect, the measuring devices comprise a container having a first side with a cavity and a second opposing side having a cavity that is larger than the cavity of the first side. The first side cavity is sized to hold an amount of food that restricts calorie intake of an animal. The second side cavity is sized to hold an amount of food that provides daily requirement for weight management of an animal.
US09968064B2 Spinach hybrid 51-521 RZ
The present invention relates to a Spinacia oleracea seed designated 51-521 RZ, which exhibits a combination of traits including fast growing, a flat plant habit, smooth mature leaves, a field resistance against Colletotrichum dematium f. sp. spinaciae and resistance to downy mildew (P. farinosa f. sp. spinaciae) races Pfs1 to Pfs15. The present invention also relates to a Spinacia oleracea plant produced by growing the 51-521 RZ seed. The invention further relates to methods for producing the spinach cultivar, represented by spinach variety 51-521 RZ.
US09968062B1 Soybean cultivar CL 1460479
The present invention is in the field of soybean variety CL1460479 breeding and development. The present invention particularly relates to the soybean variety CL1460479 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CL1460479 in a breeding program.
US09968061B1 Soybean cultivar CL1460725
The present invention is in the field of soybean variety CL1460725 breeding and development. The present invention particularly relates to the soybean variety CL1460725 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CL1460725 in a breeding program.
US09968057B2 Soybean variety 01058336
The invention relates to the soybean variety designated 01058336. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01058336. Also provided by the invention are tissue cultures of the soybean variety 01058336 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01058336 with itself or another soybean variety and plants produced by such methods.
US09968054B2 Soybean variety 01057207
The invention relates to the soybean variety designated 01057207. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01057207. Also provided by the invention are tissue cultures of the soybean variety 01057207 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01057207 with itself or another soybean variety and plants produced by such methods.
US09968052B2 Plants and seeds of hybrid corn variety CH198025
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH198025. The invention thus relates to the plants, seeds and tissue cultures of the variety CH198025, and to methods for producing a corn plant produced by crossing a corn plant of variety CH198025 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH198025.
US09968051B2 Canola hybrid cultivar G2537376H
The present invention relates to a new and distinctive canola, designated G2537376H. Also included are seeds of canola G2537376H, to the plants, or plant parts, of canola G2537376H and to methods for producing a canola plant produced by crossing the canola G2537376H with itself or another canola genotype, and the creation of variants by mutagenesis or transformation of canola G2537376H.
US09968048B1 Maize hybrid X00F910
A novel maize variety designated X00F910 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X00F910 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X00F910 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X00F910, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X00F910. This invention further relates to methods for producing maize varieties derived from maize variety X00F910.
US09968045B2 Hybrid tomato plant HMX4909
A novel hybrid tomato plant, designated HMX4909 is disclosed. The invention relates to the seeds of tomato hybrid HMX4909, to the plants and plant parts of hybrid tomato HMX4909, and to methods for producing a tomato plant by crossing the hybrid tomato HMX4909 with itself or another tomato plant. The invention further relates to methods for producing a tomato plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other tomato plants derived from the hybrid tomato plant HMX4909.
US09968039B2 Hydroponic tower assembly
A hydroponic tower for growing fruits, vegetables, herbs, flowers, and/or other plants. The tower illustratively includes a substantially vertically-oriented tube with an inlet end and a drain end. The tube defines a plurality of openings for receiving a plurality of cups that can be added to and removed from the tube as desired.
US09968035B2 Bale spear device
A bale spear device has a first upper plate having an aperture, a second upper plate having an aperture, an upper cross tube for connecting the first upper plate and the second upper plate together in a spaced apart arrangement, a first lower plate connected to the upper cross tube, a second lower plate connected to the upper cross tube, a lower cross tube for connecting the first lower plate and the second lower plate together in a spaced apart relationship, a socket extending out of the upper cross tube, a spear having a tip end and a socket end with the tip end for insertion into the aperture of the second upper plate and the socket end for insertion into the aperture of the first upper plate, and a locking device for locking the socket end of the spear in the aperture of the first upper plate.
US09974220B2 Method for fitting printed circuit boards with components
A fitting system includes a plurality of fitting lines for fitting printed circuit boards with electronic components. A method for allocating printed circuit boards to the fitting lines includes determining requirements for fitting each of a plurality of printed circuit boards with components with which the plurality of printed circuit boards are to be fitted, determining an amount of printed circuit boards of which the component variances exceed a predetermined value, each component variance representing the number of different components with which a printed circuit board is to be fitted, and allocating the printed circuit boards to the fitting lines under the predetermined conditions via integral linear programming, such that the printed circuit boards of the amount are distributed as uniformly as possible over the fitting lines.
US09974206B2 Computer internal architecture
An internal component and external interface arrangement for a cylindrical compact computing system is described that includes at least a structural heat sink having triangular shape disposed within a cylindrical volume defined by a cylindrical housing. A computing engine having a generally triangular shape is described having internal components that include a graphics processing unit (GPU) board, a central processing unit (CPU) board, an input/output (I/O) interface board, an interconnect board, and a power supply unit (PSU).
US09974205B1 Cable management bracket with side clamps
An apparatus for securing cables in a computer rack is provided. The apparatus includes a bracket attachable to one of a computer chassis arranged in the computer rack or a vertical structural member of the computer rack, and including an outward-facing surface and a first connector feature arranged on the outward-facing surface. The apparatus also includes a cable clamp. The cable clamp includes a base having a first side and an opposing second side. The first side includes a surface configured to receive cables. The second side includes a second connector feature configured for mating engagement with the first connector feature such that the base is attached to the bracket when the first and second connector features are matingly engaged. The cable clamp also includes a pliable retention strap attached to the base and configured to be wrapped around the cables such that the cables are secured to the base.
US09974203B1 Rack system for supporting a computing device
A rack system for supporting a computing device includes an adaptor. The adaptor includes a first support portion defining an opening that is aligned with a rack opening of a rack support post. The first support portion and the rack support post receive a fastener through the opening and the rack opening to attach the adaptor to the rack support post. A second support portion is attached to an end of the first support portion. The second support portion includes a first wall and a second wall that are spaced apart to define a flange opening. A support arm includes a flange having a body portion and an attachment portion. The attachment portion is received within the flange opening to attach the support arm to the adaptor. A rail is attached to the body portion of the flange. The support arm is attached to the rack support post, via the adaptor.
US09974193B2 Coating metal foil with N-heterocyclic carbene compounds containing organic functionalities for improving metal-to-resin adhesion
A carbene-coated metal foil is produced by applying an N-heterocyclic carbene (NHC) compound to one or more surfaces of a metal foil (e.g., an electrodeposited copper foil having a surface that is smooth and non-oxidized). The NHC compound contains a matrix-reactive pendant group that includes at least one of a vinyl-, allyl-, acrylic-, methacrylic-, styrenic-, amine-, amide- and epoxy-containing moiety capable of reacting with a base polymer (e.g., a vinyl-containing resin such as a polyphenylene oxide/triallyl-isocyanurate (PPO/TAIC) composition). The NHC compound may be synthesized by, for example, reacting a halogenated imidazolium salt (e.g., 1,3-bis(4-bromo-2,6-dimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium chloride) and an organostannane having a vinyl-containing moiety (e.g., tributyl(vinyl)stannane) in the presence of a palladium catalyst. In some embodiments, an enhanced substrate for a printed circuit board (PCB) is produced by laminating the carbene-coated metal foil to a substrate that includes glass fiber impregnated with the base polymer.
US09974192B2 Method of manufacturing an intermediate product for an interposer and intermediate product for an interposer
A method of manufacturing an intermediate product for an interposer including a glass substrate having a plurality of through holes is provided. The method includes a step of forming a resin layer on a support substrate, and a step of forming a laminated body by adhering the glass substrate having the plurality of through holes on the resin layer. The glass substrate having the plurality of through holes has a thickness within a range of 0.05 mm to 0.3 mm.
US09974190B2 System and method of providing a semiconductor carrier and redistribution structure
In an embodiment, a method includes arranging a first carrier on a first major surface of a circuit board such that an electronic component arranged on the first carrier is positioned in an aperture in the circuit board and spaced apart from side walls of the aperture, and arranging a second carrier on a second major surface of the circuit board such that the second carrier covers the electronic component and the aperture, the second major surface of the circuit board opposing the first major surface of the circuit board. The electronic component includes a power semiconductor device embedded in a dielectric core layer and at least one contact pad arranged on a first major surface of the dielectric core layer.
US09974188B2 Patterning of graphene circuits on flexible substrates
A process for forming a graphene circuit pattern on an object is described. A graphene layer is grown on a metal foil. A bonding layer is formed on a protective film and a surface of the bonding layer is roughened. The graphene layer is transferred onto the roughened surface of the bonding layer. The protective film is removed and the bonding layer is laminated to a first core dielectric substrate. The metal foil is etched away. Thereafter the graphene layer is etched using oxygen plasma etching to form graphene circuits on the first core dielectric substrate. The first core dielectric substrate having graphene circuits thereon is bonded together with a second core dielectric substrate wherein the graphene circuits are on a side facing the second core dielectric substrate wherein an air gap is left therebetween.
US09974172B2 Epoxy resin compound and radiant heat circuit board using the same
An epoxy resin compound having an epoxy resin, a curing agent, and inorganic filler as main components is provided. The epoxy resin includes an epoxy resin of Chemical Formula. Accordingly, the thermal conductivity of the epoxy resin compound can be increased because the epoxy resin has a mesogen structure that facilitates crystallizability. In addition, a high radiant heat board can be provided by using the above-mentioned epoxy resin as an insulating material for a printed circuit board.
US09974170B1 Conductive strands for fabric-based items
Strands of material may be intertwined using weaving techniques, knitting techniques, non-woven or entanglement techniques, or braiding techniques. Fabric that is formed from the strands of material may be used in forming a fabric-based item. The fabric based item may include electrical components. The strands may include conductive strands that form signal paths. The signal paths can carry electrical signals associated with operation of the electrical components. Each strand may have an elongated core and a coating. Strands may also include intermediate layers between the cores and coatings. The cores, intermediate layers, and coatings may be formed from polymer without conductive filler, polymer with conductive filler, and/or metal. A polymer core may be provided with recesses to help retain subsequently deposited layers such as a metal coating layer. The recesses may be grooves that extend along the longitudinal axis of the core.
US09974169B2 Resin composition, prepreg, metal-foil-clad laminate, resin composite sheet, and printed wiring board
A resin composition for a printed wiring board containing a cyanate compound (A); a maleimide compound (B); and a benzoguanamine compound (C) having an aminomethyl group represented by the following general formula (1): wherein R is a hydrogen atom or a substituent selected from a group consisting of a hydrocarbon group having 1 to 10 carbon atoms, an alkoxyl group having 1 to 10 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, a hydroxyl group, an amide group, and a halogen atom, and n is an integer of 1 to 2.
US09974168B2 Insulating ceramic paste, ceramic electronic component, and method for producing the same
Provided are an insulating ceramic paste, a ceramic electronic component, and a method for producing the ceramic electronic component that allow prevention of solder shorts between narrow-pitch terminal electrodes and suppression of generation of cracks in an insulator covering a portion of terminal electrodes during a firing step. The ceramic electronic component includes a ceramic multilayer substrate, terminal electrodes formed on a surface of the ceramic multilayer substrate, and an insulating ceramic film formed on the surface of the ceramic multilayer substrate so as to cover a portion of the terminal electrodes. An exposed surface portion (celsian-crystal-rich layer) of the insulating ceramic film has a thermal expansion coefficient that is lower than the thermal expansion coefficient of the ceramic multilayer substrate.
US09974162B2 Interconnection substrate and method of inspecting interconnection substrate
An interconnection substrate having a barcode includes a core layer, an interconnection layer over a first surface of the core layer, an insulating layer to cover the interconnection layer, and one or more additional interconnection layers over the insulating layer, wherein the barcode includes cells arranged at spaced intervals, and a cell pattern is made by forming penetrating holes through the core layer in some of the cells but not in remaining ones of the cells, wherein the penetrating holes are filled with resin, and an end face of the resin is exposed on the same side as the first surface such that the interconnection layer is situated in a surrounding area of the end face but not over the end face, and wherein a number of interconnection layers over the end face is smaller than a number of interconnection layers in the surrounding area of the end face.
US09974156B2 Circular accelerator, circular accelerator operation method, and particle-beam therapy device
A circular accelerator that accelerates charged particles orbiting along an orbital path to a predetermined energy to perform, by deviating the path from the orbital path to an extraction path, extraction of the charged particles exceeding a stable region formed by multipole electromagnets, includes a multipole electromagnet energization control unit setting energization of the multipole electromagnets so that part of the charged particles are deviated to a discarding path other than the extraction path to discard unwanted charged particles, and then setting energization of the multipole electromagnets so that the charged particles orbiting in the orbital path are deviated to the extraction path to perform extraction of the charged particles.
US09974155B2 Variable-pulse-shape pulsed-power accelerator
A variable-pulse-shape pulsed-power accelerator is driven by a large number of independent LC drive circuits. Each LC circuit drives one or more coaxial transmission lines that deliver the circuit's output power to several water-insulated radial transmission lines that are connected in parallel at small radius by a water-insulated post-hole convolute. The accelerator can be impedance matched throughout. The coaxial transmission lines are sufficiently long to transit-time isolate the LC drive circuits from the water-insulated transmission lines, which allows each LC drive circuit to be operated without being affected by the other circuits. This enables the creation of any power pulse that can be mathematically described as a time-shifted linear combination of the pulses of the individual LC drive circuits. Therefore, the output power of the convolute can provide a variable pulse shape to a load that can be used for magnetically driven, quasi-isentropic compression experiments and other applications.
US09974150B2 Secure device rejoining for mesh network devices
Securing device rejoining for a mesh network of a wireless lighting control system is disclosed. A potential security weakness of a mesh network protocol is that a proprietary link key may be discovered by close, expert examination of a device, potentially facilitating the joining of a “rogue” device to the network. Requiring subsequent rejoins of any device that had previously joined the network to use a current randomly generated link key, rather than the proprietary link key, prevents rogue devices only having the proprietary link key from joining.