发明专利
IL293088A Process for the preparation of n-((1r,2s,5r)-5-(tert-butylamino)-2-((s)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide
未知
基本信息:
- 专利标题： Process for the preparation of n-((1r,2s,5r)-5-(tert-butylamino)-2-((s)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide
- 申请号：IL29308822 申请日：2022-05-17
- 公开(公告)号：IL293088A 公开(公告)日：2022-07-01
- 发明人： FAN YU , AYTAR BURCU SELIN , DEERBERG JOERG , BOROVIKA ALINA , CHAN COLLIN , DOMAGALSKI NATHAN R , EASTGATE MARTIN D , FENSTER MICHAEL DAVID BENGT , FOREST ROBERT V , GONZALEZ-BOBES FRANCISCO , GREEN REBECCA A , HICKEY MATTHEW R , KOPP NATHANIEL DAVID , LA CRUZ THOMAS E , LAUSER KATHLEEN , LEE HONG GEUN , LEAHY DAVID K , LUO HELEN Y , RAZLER THOMAS M , SAVAGE SCOTT A , SFOUGGATAKIS CHRIS , SOUMEILLANT MAXIME C D , ZHENG BIN , ZARETSKY SERGE , ZHU YE
- 申请人： SQUIBB BRISTOL MYERS CO , AYTAR BURCU SELIN , DEERBERG JOERG , BOROVIKA ALINA , CHAN COLLIN , FAN YU , DOMAGALSKI NATHAN R , EASTGATE MARTIN D , FENSTER MICHAEL DAVID BENGT , FOREST ROBERT V , GONZALEZ BOBES FRANCISCO , GREEN REBECCA A , HICKEY MATTHEW R , KOPP NATHANIEL DAVID , LA CRUZ THOMAS E , LAUSER KATHLEEN , LEE HONG GEUN , LEAHY DAVID K , LUO HELEN Y , RAZLER THOMAS M , SAVAGE SCOTT A , SFOUGGATAKIS CHRIS , SOUMEILLANT MAXIME C D , ZHENG BIN , ZARETSKY SERGE , ZHU YE
- 专利权人： SQUIBB BRISTOL MYERS CO,AYTAR BURCU SELIN,DEERBERG JOERG,BOROVIKA ALINA,CHAN COLLIN,FAN YU,DOMAGALSKI NATHAN R,EASTGATE MARTIN D,FENSTER MICHAEL DAVID BENGT,FOREST ROBERT V,GONZALEZ BOBES FRANCISCO,GREEN REBECCA A,HICKEY MATTHEW R,KOPP NATHANIEL DAVID,LA CRUZ THOMAS E,LAUSER KATHLEEN,LEE HONG GEUN,LEAHY DAVID K,LUO HELEN Y,RAZLER THOMAS M,SAVAGE SCOTT A,SFOUGGATAKIS CHRIS,SOUMEILLANT MAXIME C D,ZHENG BIN,ZARETSKY SERGE,ZHU YE
- 当前专利权人： SQUIBB BRISTOL MYERS CO,AYTAR BURCU SELIN,DEERBERG JOERG,BOROVIKA ALINA,CHAN COLLIN,FAN YU,DOMAGALSKI NATHAN R,EASTGATE MARTIN D,FENSTER MICHAEL DAVID BENGT,FOREST ROBERT V,GONZALEZ BOBES FRANCISCO,GREEN REBECCA A,HICKEY MATTHEW R,KOPP NATHANIEL DAVID,LA CRUZ THOMAS E,LAUSER KATHLEEN,LEE HONG GEUN,LEAHY DAVID K,LUO HELEN Y,RAZLER THOMAS M,SAVAGE SCOTT A,SFOUGGATAKIS CHRIS,SOUMEILLANT MAXIME C D,ZHENG BIN,ZARETSKY SERGE,ZHU YE
- 优先权： US201762534908 2017-07-20
摘要：
The invention generally relates to an improved process for the preparation of N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide,as well as novel intermediates employed in the process, which may be useful for the treatment of cancer.