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91. 发明授权

US10093916B2 Method for reducing or inactivating viral and microbial content in the processes for the manufacture of pancreatin 有权
公开(公告)号：US10093916B2
公开(公告)日：2018-10-09
申请号：US15159345
申请日：2016-05-19
申请人： Kenneth S. Manning , Yan Wang , Dustin Nielsen , Ryan Ruf , Colin Crowley , Jon Restivo , Dana Spangenberg , Karla Anhalt , Mark Romich , Anisha Akula , Carmen Fritz
发明人： Kenneth S. Manning , Yan Wang , Dustin Nielsen , Ryan Ruf , Colin Crowley , Jon Restivo , Dana Spangenberg , Karla Anhalt , Mark Romich , Anisha Akula , Carmen Fritz
IPC分类号： C12N9/00 , C12N9/94 , A61K38/46 , C12N7/00 , A61K9/00 , A61K35/39 , A61K31/327
摘要： A method for the reduction or inactivation of viral and microbial content in the manufacturing of pancreatin API is disclosed. The method includes treating animal-derived tissue with peracetic acid to reduce viral activity and bacterial load prior to processing. In particular, the method includes treating porcine pancreas glands with peracteic acid prior to extracting a pancreatin API from the treated glandular tissue.

92. 发明申请

US20180258465A1 Methods and Devices for Performing Real Time Digital PCR 审中-公开
公开(公告)号：US20180258465A1
公开(公告)日：2018-09-13
申请号：US15901900
申请日：2018-02-22
申请人： Yan Wang
发明人： Yan Wang
IPC分类号： C12Q1/686 , B01L3/00 , B01L7/00
CPC分类号： C12Q1/686 , B01L3/502784 , B01L7/52 , B01L7/525 , B01L2200/10 , B01L2300/0816 , B01L2300/0829 , B01L2300/0861 , B01L2300/0883 , B01L2300/1822 , B01L2300/1827 , C12Q2537/143 , C12Q2561/113 , C12Q2563/159 , C12Q2565/629
摘要： Disclosed are devices that can perform multiple independent digital PCRs with real time monitoring capability. The device comprises multiple PCR mini-reactors thermally coupled with its own temperature control element, a detection unit, and a motorized platform for holding and moving the PCR mini-reactors. The real time digital PCR device can simultaneously perform multiple digital PCRs, generate amplification curves of thousands and millions of individual PCR processes, evaluate binary readouts based on the amplification curves, and identify different target sequences based on the amplification curves. Methods of using the real time digital PCR device to detect target nucleic acid and count circulating tumor cells are also disclosed.

93. 发明授权

US09768460B2 Hydrogen oxidation and generation over carbon films 有权
公开(公告)号：US09768460B2
公开(公告)日：2017-09-19
申请号：US13994906
申请日：2011-12-16
申请人： Andrew Gabriel Rinzler , Rajib Kumar Das , Yan Wang , Hai-Ping Cheng
发明人： Andrew Gabriel Rinzler , Rajib Kumar Das , Yan Wang , Hai-Ping Cheng
IPC分类号： H01M8/06 , H01M8/0656 , H01M4/90 , H01M4/96 , H01M8/0234 , H01M8/0239 , H01M8/18 , C25B11/12 , H01M4/86 , H01M4/88
CPC分类号： H01M8/0656 , C25B11/12 , H01M4/8615 , H01M4/8825 , H01M4/90 , H01M4/96 , H01M8/0234 , H01M8/0239 , H01M8/186 , H01M2250/10 , H01M2250/402 , Y02B90/12 , Y02B90/14 , Y02E60/528 , Y02P20/133
摘要： An electrode comprises an acid treated, cathodically cycled carbon-comprising film or body. The carbon consists of single walled nanotubes (SWNTs), pyrolytic graphite, microcrystalline graphitic, any carbon that consists of more than 99% sp2 hybridized carbons, or any combination thereof. The electrode can be used in an electrochemical device functioning as an electrolyzer for evolution of hydrogen or as a fuel cell for oxidation of hydrogen. The electrochemical device can be coupled as a secondary energy generator into a system with a primary energy generator that naturally undergoes generation fluctuations. During periods of high energy output, the primary source can power the electrochemical device to store energy as hydrogen, which can be consumed to generate electricity as the secondary source during low energy output by the primary source. Solar cells, wind turbines and water turbines can act as the primary energy source.

94. 发明授权

US09622095B2 Method and device for maintaining long term evolution base station 有权
公开(公告)号：US09622095B2
公开(公告)日：2017-04-11
申请号：US13382521
申请日：2010-07-09
申请人： Weiguo Ma , Bing Liu , Jiye Tang , Yan Wang
发明人： Weiguo Ma , Bing Liu , Jiye Tang , Yan Wang
IPC分类号： H04W76/02 , H04W24/04 , H04W88/08 , H04W92/12
CPC分类号： H04W24/04 , H04W76/10 , H04W88/08 , H04W92/12
摘要： A method and a device for maintaining a Long Term Evolution (LTE) base station are provided by the embodiments of the present invention. Depending on the LTE access network system and air interface characteristics, by making a few processing flow changes in such mode or method, a wireless communication link is established between a network maintenance device and a base station to implement the base station maintenance and data communication. Application of the technical solutions provided by the embodiments of the present invention can implement the base station maintenance and data communication by the wireless mode, reduce the cost of the network maintenance and prevent the destruction and influence of human factors on the operation and maintenance of the base station.

95. 发明授权

US09598527B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same 有权
公开(公告)号：US09598527B2
公开(公告)日：2017-03-21
申请号：US11638876
申请日：2006-12-14
申请人： Thomas G. Rukavina , Robert Hunia , Yan Wang
发明人： Thomas G. Rukavina , Robert Hunia , Yan Wang
IPC分类号： C08G18/32 , C08G18/42 , C08G18/44 , C08G18/73 , C08G18/75 , C08G18/76 , C08G18/79 , C09D175/04 , B32B27/40 , B32B9/00 , B32B27/12 , B32B27/10 , B32B27/08 , B32B21/08 , B32B15/08 , B32B9/04 , B32B11/04 , B32B13/12
CPC分类号： C08G18/3206 , B32B9/005 , B32B9/045 , B32B11/046 , B32B13/12 , B32B15/08 , B32B21/08 , B32B27/08 , B32B27/10 , B32B27/12 , B32B27/40 , B32B2307/302 , B32B2307/412 , B32B2307/54 , B32B2307/554 , B32B2307/558 , B32B2307/712 , B32B2307/718 , B32B2551/00 , B32B2571/02 , C08G18/3203 , C08G18/3212 , C08G18/3221 , C08G18/4277 , C08G18/44 , C08G18/73 , C08G18/758 , C08G18/765 , C08G18/7671 , C08G18/792 , C08G18/798 , C09D175/04 , Y10T428/249924 , Y10T428/31551 , Y10T428/31591 , Y10T428/31601
摘要： The present invention provides polyurethanes including a reaction product of components including: (a) about 1 equivalent of at least one polyisocyanate; (b) about 0.05 to about 0.9 equivalents of at least one branched polyol having 4 to 18 carbon atoms and at least 3 hydroxyl groups; and (c) about 0.1 to about 0.95 equivalents of at least one diol having 2 to 18 carbon atoms, wherein the reaction product components are essentially free of polyester polyol and polyether polyol and the reaction components are maintained at a temperature of at least about 100° C. for at least about 10 minutes, compositions, coatings and articles made therefrom and methods of making the same.

96. 发明授权

US09493824B2 Universal reference dye for quantitative amplification 有权
标题翻译：通用参比染料用于定量扩增
公开(公告)号：US09493824B2
公开(公告)日：2016-11-15
申请号：US13328154
申请日：2011-12-16
申请人： Yan Wang
发明人： Yan Wang
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6851 , C12Q2527/125 , C12Q2527/137 , C12Q2563/107
摘要： Universal reference dye mixtures for quantitative amplification, and uses thereof, are provided.
摘要翻译：提供用于定量扩增的通用参考染料混合物及其用途。

97. 发明申请

US20160201131A1 Method for Identifying Drug Resistance Related Mutations 审中-公开
标题翻译：鉴别耐药相关突变的方法
公开(公告)号：US20160201131A1
公开(公告)日：2016-07-14
申请号：US14879099
申请日：2015-10-09
申请人： Yan Wang , Jianming Xu , Chun Gong
发明人： Yan Wang , Jianming Xu , Chun Gong
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q1/6809 , C12Q2600/106 , C12Q2600/156 , C12Q2535/122 , C12Q2537/165
摘要： The present invention provides a method for detecting low frequency drug resistant mutations using ultra deep amplicon sequencing. Multiple selection criteria based on biological relevance were applied to filter out low frequency background noise and lead to reliable identification of drug resistance related mutations. A method to predict the occurrence of drug resistance during the treatment is also provided.
摘要翻译：本发明提供使用超深度扩增子测序检测低频耐药性突变的方法。应用基于生物相关性的多种选择标准来筛选低频背景噪声，并导致耐药相关突变的可靠鉴定。还提供了一种预测治疗期间耐药性发生的方法。

98. 发明授权

US09325788B2 Method, device and system for processing a network mapping identifier, and peer selection method 有权
标题翻译：用于处理网络映射标识符的方法，设备和系统，以及对等体选择方法
公开(公告)号：US09325788B2
公开(公告)日：2016-04-26
申请号：US13347882
申请日：2012-01-11
申请人： Yan Wang , Guoyi Chen
发明人： Yan Wang , Guoyi Chen
IPC分类号： G06F15/16 , H04L29/08 , H04L12/701 , H04L12/751 , H04L29/12
CPC分类号： H04L67/104 , H04L29/1232 , H04L45/00 , H04L45/02
摘要： A method, a device and a system for processing a network mapping identifier, and a peer selection method are provided, in which the method includes: obtaining topology information of a network, in which the topology information includes a relation between nodes in the network; generating a network mapping identifier capable of indicating a relation between a peer and other peers in the network according to the topology information; and combining the generated network mapping identifier and an Internet Service Provider (ISP) identifier into a network mapping identifier, and allocating the network mapping identifier to the peer. Through the method, the device and the system, the network topology information of an ISP is protected from being exposed, a load on the ISP is reduced, and private information of a peer-to-peer (p2p) application system is capable of being protected.
摘要翻译：提供了一种用于处理网络映射标识符的方法，设备和系统以及对等体选择方法，其中所述方法包括：获取网络的拓扑信息，其中所述拓扑信息包括所述网络中的节点之间的关系; 生成能够根据拓扑信息指示网络中的对等体与其他对等体之间的关系的网络映射标识符; 以及将所生成的网络映射标识符和因特网服务提供商（ISP）标识符组合成网络映射标识符，并将所述网络映射标识符分配给所述对等体。通过该方法，设备和系统，保护ISP的网络拓扑信息不被暴露，ISP上的负载减少，对等（p2p）应用系统的私有信息能够被保护。

99. 发明授权

US09293777B2 Battery electrolyte suspension 有权
标题翻译：电池电解液悬浮液
公开(公告)号：US09293777B2
公开(公告)日：2016-03-22
申请号：US13892478
申请日：2013-05-13
申请人： Yan Wang , Diran Apelian , Yang Bai , Wenhuan Li
发明人： Yan Wang , Diran Apelian , Yang Bai , Wenhuan Li
IPC分类号： H01M8/06 , H01M8/04 , H01M8/18 , H01M8/22
CPC分类号： H01M8/04798 , H01M8/04276 , H01M8/188 , H01M8/225 , Y02E60/528
摘要： A flow battery employs a solid suspension charge material to maintain high charge density via stability of a suspension including a binder, conductive carbon and an electrolyte. A cathodic suspension employs carbon powder as a stabilizing agent in a suspension form to avoid precipitation of solids and maintain a high surface area of the suspended solids. The stabilizing agent undergoes agitation and milling to reduce a particle size and increase the change density due to the conductive nature of the fine powdered stabilizing agent exhibiting high energy density. The resulting suspensions are circulated in a charge cell connected to a load for providing electrical power.
摘要翻译：流动电池采用固体悬浮电荷材料，以通过包括粘合剂，导电碳和电解质的悬浮液的稳定性来保持高电荷密度。阴极悬浮液使用碳粉作为悬浮液形式的稳定剂，以避免固体沉淀并保持悬浮固体的高表面积。由于表现出高能量密度的细粉状稳定剂的导电性质，稳定剂经历搅拌和研磨以降低粒度并增加变化密度。所得到的悬浮液在连接到用于提供电力的负载的充电单元中循环。

100. 发明授权

US09243569B2 Variable cam timing control during engine shut-down and start-up 有权
标题翻译：发动机关闭和启动期间可变凸轮定时控制
公开(公告)号：US09243569B2
公开(公告)日：2016-01-26
申请号：US13439742
申请日：2012-04-04
申请人： Yan Wang , James Douglas Ervin , Kim Hwe Ku
发明人： Yan Wang , James Douglas Ervin , Kim Hwe Ku
IPC分类号： F02D13/08
CPC分类号： F02D13/08 , F01L1/344 , F01L1/352 , F01L2001/3522 , Y02T10/18
摘要： A method for controlling an electric variable cam timing (VCT) actuator is disclosed. The method includes during engine shutdown, adjusting camshaft position with an electric VCT actuator to a target starting location, applying a first current to the electric VCT actuator to maintain the target starting location, and during engine startup before camshaft position feedback becomes available, applying a second current to the electric VCT actuator to maintain the target starting location.
摘要翻译：公开了一种用于控制电动凸轮定时（VCT）致动器的方法。该方法包括在发动机关闭期间，利用电动VCT致动器将凸轮轴位置调整到目标起始位置，向电气VCT致动器施加第一电流以维持目标起始位置，并且在凸轮轴位置反馈变得可用之前的发动机起动期间，第二电流到电动VCT执行器，以维持目标起始位置。

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