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91. 发明申请

US20170274132A1 METHOD AND APPARATUS FOR THE DIALYSIS OF BLOOD 审中-公开
公开(公告)号：US20170274132A1
公开(公告)日：2017-09-28
申请号：US15619066
申请日：2017-06-09
申请人： Phase One Medical, LLC
发明人： Adrian Ravenscroft , Donald Woods
IPC分类号： A61M1/36 , A61M25/00 , A61M25/01 , A61M39/22 , A61M39/08
CPC分类号： A61M1/3661 , A61M1/3659 , A61M25/0021 , A61M25/0026 , A61M25/003 , A61M25/0067 , A61M25/007 , A61M25/0071 , A61M25/0194 , A61M39/22 , A61M2025/0031 , A61M2025/0037 , A61M2025/0073 , A61M2039/082 , A61M2039/226
摘要： Apparatus for use in dialyzing a patient, the apparatus comprising: a hemodialysis catheter comprising: an elongated body having a proximal end and a distal end, wherein the distal end terminates in a substantially planar distal end surface; first and second lumens extending from the proximal end of the elongated body to the distal end of the elongated body, wherein the first and second lumens terminate on the substantially planar distal end surface in first and second mouths, respectively, arranged in side-by-side configuration, and further wherein the first and second lumens are separated by a septum; and first and second longitudinal slots formed in the distal end of the elongated body and communicating with the interiors of the first and second lumens, respectively, the first and second longitudinal slots opening on the substantially planar distal end surface; wherein the first and second longitudinal slots each has a length and a width, relative to the dimensions of the first and second lumens and the rate of blood flow to be passed through the hemodialysis catheter, such that (i) when a given lumen is to be used for a return function, the primary blood flow will exit the mouth of that lumen, and (ii) when a given lumen is to be used for a suction function, the primary blood flow will enter the proximal end of the longitudinal slot associated with that lumen, whereby to minimize undesirable recirculation of dialyzed blood.

92. 发明申请

US20170172796A1 SURGICAL SYSTEM WITH SUBSTANCE DELIVERY SYSTEM 审中-公开
公开(公告)号：US20170172796A1
公开(公告)日：2017-06-22
申请号：US15378441
申请日：2016-12-14
申请人： Novartis AG
发明人： Philip John Biancalana , Mark Alan Hopkins , Michael James Papac , Robert Joseph Sanchez, JR.
IPC分类号： A61F9/007 , A61M5/00 , A61M39/24
CPC分类号： A61M5/007 , A61F9/00745 , A61M39/24 , A61M2039/226
摘要： A microsurgical system with an integrated substance chamber is provided herein for delivering substance (e.g., a drug, retina patch, dye, etc.) to a surgical site through a tool component of the microsurgical instrument, such as a tissue removal component. The system may include a tissue removal handpiece having a tissue cutter disposed at a distal end. The system may further include a first fluid conduit and a second fluid conduit. The first fluid conduit may couple a fluidics subsystem to the tissue removal handpiece to permit removal of cut tissue. The second fluid conduit may couple a substance chamber to the tissue removal handpiece. The system may additionally include a control system that enables or facilitates selective control of fluid through the tissue removal handpiece to introduce substance from the substance chamber to a surgical site through a port in the tissue cutter.

93. 发明授权

US09554937B2 Penile prosthetic pump having an inlet valve with a lockout flange 有权
标题翻译：阴茎假体泵具有带有锁定法兰的入口阀
公开(公告)号：US09554937B2
公开(公告)日：2017-01-31
申请号：US14304984
申请日：2014-06-16
申请人： Coloplast A/S
发明人： Geoffrey A. Daniel
IPC分类号： A61F2/26 , A61F5/41 , A61M39/22
CPC分类号： A61F2/26 , A61F5/41 , A61F2005/415 , A61F2250/0003 , A61F2250/0013 , A61M39/227 , A61M2039/226
摘要： A pump includes a pump bulb connected to a pump body. An exhaust valve assembly is disposed in the pump body within an exit flow path communicating between the pump bulb and the cylinder. An inlet valve is rotatably disposed in the pump body within an inlet flow path communicating between the reservoir and the pump bulb. The inlet valve includes a spherical part retained in a seat formed by the pump body, an inlet flange connected to and extending radially away from the spherical part, and a lockout flange connected to and extending radially away from the spherical part. A channel is formed through a portion of the spherical part of the inlet valve. The channel includes an outlet hole that is blocked from the inlet flow path by the seat formed in the pump body and opened to the inlet flow path by rotation of the inlet valve.
摘要翻译：泵包括连接到泵体的泵泡。排气门组件设置在泵主体内的泵管和气缸之间连通的出口流动路径内。入口阀可旋转地设置在泵本体内的入口流动路径之间，该入口流动路径在储存器和泵灯泡之间连通。入口阀包括保持在由泵体形成的座中的球形部分，与球形部分连接并径向延伸的入口凸缘，以及连接到径向远离球形部分并从球形部分径向延伸的锁定凸缘。通过入口阀的球形部分的一部分形成通道。通道包括出口孔，该出口孔通过形成在泵体中的座部从入口流动路径阻挡并且通过入口阀的旋转而向入口流动路径敞开。

94. 发明授权

US09463311B2 Valves, valved fluid transfer devices and ambulatory infusion devices including the same 有权
标题翻译：阀，阀门流体输送装置和包括其的流动输液装置
公开(公告)号：US09463311B2
公开(公告)日：2016-10-11
申请号：US14594114
申请日：2015-01-10
申请人： Medallion Therapeutics, Inc.
发明人： Susan McConnell , Keith A. Oberg , Lawrence S. Ring , Peter C. Lord
IPC分类号： A61M39/22 , A61M5/142 , A61M5/168 , F16K1/32
CPC分类号： A61M5/16881 , A61M5/14216 , A61M5/14276 , A61M5/16804 , A61M5/16813 , A61M39/22 , A61M39/24 , A61M2039/226 , A61M2205/0216 , A61M2205/0222 , A61M2205/18 , A61M2205/3317 , A61M2205/3331 , A61M2205/50 , A61M2205/52 , A61M2205/75 , A61M2205/8206 , F16K1/32
摘要： Valves, valved fluid transfer devices and ambulatory infusion devices including the same.
摘要翻译：阀，阀门流体输送装置和包括其的流动输液装置。

95. 发明授权

US09415151B2 Blood flow reversal valves and related systems and methods 有权
标题翻译：血流逆转阀及相关系统及方法
公开(公告)号：US09415151B2
公开(公告)日：2016-08-16
申请号：US13785537
申请日：2013-03-05
申请人： Fresenius Medical Care Deutschland GmbH , Fresenius Medical Care Holdings, Inc.
发明人： Christian Schlaeper , Harald Peter , Martin Joseph Crnkovich
IPC分类号： A61M1/30 , F16K11/085 , A61M39/22 , A61M1/36 , F16K11/074
CPC分类号： A61M39/223 , A61M1/30 , A61M1/367 , A61M2039/226 , F16K11/074
摘要： This disclosure relates to blood flow reversal valves and related systems and methods. In certain aspects of the invention, a blood flow reversal valve includes a first member having a first passage and a second passage, and a second member having a first passage and a second passage. The first and second members are rotatably fixed relative to one another such that the first passage of the first member is aligned with the first passage of the second member and the second passage of the first member is aligned with the second passage of the second member. A flow directing element is disposed in the cavity and is moveable relative to the first and second members between a first position in which the first passage of the first member and the first passage of the second member are fluidly connected and a second position in which the first passage of the first member and the second passage of the second member are fluidly connected.
摘要翻译：本公开涉及血流逆转阀及相关系统和方法。在本发明的某些方面，血流反转阀包括具有第一通道和第二通道的第一构件和具有第一通道和第二通道的第二构件。第一和第二构件相对于彼此可旋转地固定，使得第一构件的第一通道与第二构件的第一通道对准，并且第一构件的第二通道与第二构件的第二通道对准。流动引导元件设置在空腔中并且可相对于第一和第二构件在第一位置和第二位置之间移动，在第一位置和第二位置之间，第一位置与第二构件的第一通道流体连通，第二位置第一构件的第一通道和第二构件的第二通道流体连接。

96. 发明授权

US09354640B2 Smart actuator for valve 有权
标题翻译：阀门智能执行器
公开(公告)号：US09354640B2
公开(公告)日：2016-05-31
申请号：US14077112
申请日：2013-11-11
申请人： Fresenius Medical Care Holdings, Inc.
发明人： Terry Lynn Byler
IPC分类号： A61M39/22 , F16K31/04 , G05D16/20 , F16K37/00 , A61M1/14
CPC分类号： G05D16/202 , A61M1/14 , A61M39/22 , A61M2039/226 , A61M2205/10 , A61M2205/128 , A61M2205/332 , A61M2205/3331 , F16K31/04 , F16K37/0083 , Y10T137/7761
摘要： A system and method of monitoring and controlling the open and close states of a manifold diaphragm type valve includes using an actuator mechanism with feedback control. A pressure transducer and/or force gauge located on the contact end of the actuator mechanism monitors the pressure and/or force applied to the end of the actuator mechanism. A controller instructs the actuator mechanism to move forward or backward an appropriate distance based on the monitored pressure and/or force. Temperature and pressure changes in the system and material changes to the diaphragm are sensed immediately and positioning correction is applied to the actuator in real-time, thereby maintaining the same valve state while monitoring pressure separately. The linear actuator functions as a ‘smart’ actuator, capable of fine tune adjustments without additional outside monitoring and providing a more accurate and reliable method of closing the valve in a dynamic environment.
摘要翻译：一种监测和控制歧管隔膜式阀的打开和关闭状态的系统和方法包括使用具有反馈控制的致动器机构。位于致动器机构的接触端上的压力传感器和/或力计量器监测施加到致动器机构端部的压力和/或力。控制器指示致动器机构基于所监视的压力和/或力而向前或向后移动适当的距离。立即感测到系统中的温度和压力变化以及膜片的材料变化，实时地对致动器进行定位校正，从而在分别监视压力的同时保持相同的阀状态。线性致动器可作为“智能”执行器，能够进行微调，无需额外的外部监控，并提供更准确可靠的在动态环境中关闭阀门的方法。

97. 发明申请

US20160101270A1 DRAINAGE SYSTEMS FOR EXCESS BODY FLUIDS AND ASSOCIATED METHODS 审中-公开
标题翻译：排水系统，用于超越体液和相关方法
公开(公告)号：US20160101270A1
公开(公告)日：2016-04-14
申请号：US14973548
申请日：2015-12-17
申请人： University of Washington
发明人： Samuel R. Browd , Barry R. Lutz
IPC分类号： A61M27/00 , A61M39/28
CPC分类号： A61M27/006 , A61B5/031 , A61M27/002 , A61M39/284 , A61M2027/004 , A61M2039/226 , A61M2205/3334
摘要： Drainage systems for excess body fluids and associated methods are disclosed herein. A body fluid drainage system in accordance with an embodiment of the present technology, for example, can include a catheter that has an exterior surface, a proximal portion, and a distal portion opposite the proximal portion. The body fluid drainage system can further include a valve device, a pressure sensor, and a controller operatively coupled to the valve device and the pressure sensor. The valve device can include an actuator positioned over the exterior surface of the catheter. The actuator is movable between an open position that allows body fluid flow through the catheter, a closed position that at least substantially obstructs the body fluid flow through the catheter, and intermediate positions that partially obstruct the body fluid flow through the catheter. The controller can change the position of the actuator in response to a predetermined condition of the pressure sensor.
摘要翻译：本文公开了用于过量体液和相关方法的排水系统。根据本技术的实施例的体液排出系统例如可以包括具有外表面，近端部分和与近端部分相对的远侧部分的导管。体液排出系统还可以包括阀装置，压力传感器和可操作地联接到阀装置和压力传感器的控制器。阀装置可包括位于导管外表面上的致动器。致动器可以在允许体液流过导管的打开位置，至少基本上阻碍体液流过导管的关闭位置以及部分阻塞体液流过导管的中间位置之间移动。控制器可以响应于压力传感器的预定条件改变致动器的位置。

98. 发明申请

US20160089526A1 DEVICE AND METHOD FOR DISPENSING A DRUG 有权
标题翻译：用于分配药物的装置和方法
公开(公告)号：US20160089526A1
公开(公告)日：2016-03-31
申请号：US14869799
申请日：2015-09-29
申请人： Dermira, Inc.
发明人： Hans Hofland , Delphine Caroline Imbert , Daniel O'Connell , Allen Pearson
IPC分类号： A61M35/00
CPC分类号： A61M35/003 , A61M2039/226 , A61M2205/10 , A61M2205/276 , A61M2205/581 , A61M2205/583 , A61M2210/04 , B05B11/0037 , B05B11/0038 , B05B11/3059 , B05B11/308 , B05C17/00
摘要： A device for dispensing a topically administered drug has a spreader which is used to actuate a pump to release the drug and then to spread the drug on the skin and. The spreader is coupled to a lock that prevents it from actuating the pump after a number of drug doses have been dispensed. The pump can be actuated to release no more than the selected quantity of drug per day or actuation.
摘要翻译：用于分配局部给药的药物的装置具有扩张器，其用于致动泵以释放药物，然后将药物铺展在皮肤上。吊具耦合到锁，防止在已经分配了许多药物剂量之后启动泵。可以启动泵以释放不超过每天选择的药物量或致动。

99. 发明授权

US09216275B2 Adjustable height hydrocephalus valve location device 有权
标题翻译：可调高度脑积水阀定位装置
公开(公告)号：US09216275B2
公开(公告)日：2015-12-22
申请号：US14040865
申请日：2013-09-30
申请人： DePuy Synthes Products, LLC
发明人： Brian Soares , Alyssa Trigger , Michael DeFusco , Stephen F. Wilson
IPC分类号： A61M27/00 , F16K31/00
CPC分类号： A61M27/006 , A61M39/22 , A61M2039/226 , A61M2205/581 , A61M2205/582 , A61M2205/6054 , F16K31/00
摘要： An adjustable height tool for locating a magnetically readable and settable valve implanted in a living being. The locator can include a wall having a first perimeter. A platform can be disposed within the first perimeter. A valve cut-out can disposed within the platform and can approximate at least a portion of the shape of the valve. A movable foot can be disposed below the platform by which a displacement element moves the foot at least one of toward or away from the platform. This movement increases or decreases the distance between the platform and the skin/valve. Two or more recesses can be disposed in the foot and the recesses can be aligned with the valve cut-out. The displacement element can maintain the alignment of the recesses and the cut-out while moving the foot.
摘要翻译：一种可调节的高度工具，用于定位植入生活中的磁性可读和可设置的阀。定位器可以包括具有第一周边的壁。平台可以设置在第一周边内。阀门切口可以设置在平台内并且可以近似阀的形状的至少一部分。可移动的脚可以设置在平台下方，位移元件通过该位移元件使脚部朝向或远离平台移动至少一个。该运动增加或减少平台与皮肤/阀之间的距离。两个或多个凹槽可以设置在脚中，并且凹部可以与阀切口对齐。位移元件可以在移动脚时保持凹部和切口的对齐。

100. 发明申请

US20150305746A1 MAGNETICALLY ACTIVATED ARTERIOVENOUS ACCESS VALVE SYSTEM AND RELATED METHODS 有权
标题翻译：磁性激活的异常进气阀系统及相关方法
公开(公告)号：US20150305746A1
公开(公告)日：2015-10-29
申请号：US14695241
申请日：2015-04-24
申请人： CreatiVasc Medical Corporation
发明人： James S. Johnson , Frank V. Patterson , Thomas B. O'Hanlan , Jordan Jacobs
IPC分类号： A61B17/11 , A61F2/06
CPC分类号： A61B17/11 , A61B17/12045 , A61B17/12136 , A61B2017/00115 , A61B2017/00411 , A61B2017/00539 , A61B2017/00876 , A61B2017/1107 , A61B2017/1139 , A61B2090/0807 , A61F2/064 , A61F2002/068 , A61M1/3655 , A61M39/227 , A61M2039/226 , A61M2205/3331 , A61M2205/3523
摘要： In one aspect, an arteriovenous access valve system may generally include a first valve configured to be positioned at or adjacent to an end of an arteriovenous graft and a second valve configured to be positioned at or adjacent to an opposite end of the arteriovenous graft. In addition, the system may include an actuator assembly in fluid communication with the first and second valves. The actuator assembly may include a housing, a driver assembly positioned within the housing and a drive magnet positioned within the housing. The drive magnet may be rotatably coupled to the driver assembly such that, when the drive magnet is rotated, the driver assembly is configured to be rotatably driven so as to supply fluid to the first and second valves or to draw fluid out of the first and second valves depending on a rotational direction of the driver assembly.
摘要翻译：在一个方面，动静脉通路阀系统通常可以包括构造成位于动静脉移植物的端部处或邻近动静脉移植物的端部的第一阀，以及构造成定位在动静脉移植物的相对端处或邻近动静脉移植物的另一端的第二阀。另外，该系统可以包括与第一和第二阀流体连通的致动器组件。致动器组件可以包括壳体，位于壳体内的驱动器组件和位于壳体内的驱动磁体。驱动磁体可以可旋转地联接到驱动器组件，使得当驱动磁体旋转时，驱动器组件被构造成可旋转地驱动，以便将流体供应到第一和第二阀，或者将流体从第一和第二阀抽出，第二阀取决于驱动器组件的旋转方向。

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