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91. 发明申请

WO2007030311A2 ADAPTIVE RADIATION THERAPY METHOD WITH TARGET DETECTION 审中-公开
标题翻译：目标检测的自适应辐射治疗方法
公开(公告)号：WO2007030311A2
公开(公告)日：2007-03-15
申请号：PCT/US2006/032694
申请日：2006-08-23
申请人： EASTMAN KODAK COMPANY , SCHILDKRAUT, Jay Stuart , CHEN, Shoupu
发明人： SCHILDKRAUT, Jay Stuart , CHEN, Shoupu
IPC分类号： G06T5/00 , A61N5/00
CPC分类号： A61N5/1049 , A61N5/1064 , A61N5/1065 , A61N5/1069 , A61N2005/1059 , A61N2005/1061 , A61N2005/1062 , G06T7/11 , G06T7/12 , G06T7/155 , G06T7/337 , G06T2207/10124 , G06T2207/20152 , G06T2207/30061 , G06T2207/30096

92. 发明申请

WO2005036124A2 LOCALIZATION OF A TARGET USING IN VIVO MARKERS 审中-公开
标题翻译：使用生活标志的目标的本地化
公开(公告)号：WO2005036124A2
公开(公告)日：2005-04-21
申请号：PCT/US2004/027596
申请日：2004-08-25
申请人： VARIAN MEDICAL SYSTEMS TECHNOLOGIES, INC.? , MOSTAFAVI, Hassan , PARTAIN, Larry, D. , SLOUTSKY, Alexander , MUNRO, Peter
发明人： MOSTAFAVI, Hassan , PARTAIN, Larry, D. , SLOUTSKY, Alexander , MUNRO, Peter
IPC分类号： G01N
CPC分类号： A61N5/1039 , A61B6/032 , A61B6/4417 , A61B90/10 , A61B90/39 , A61B2090/101 , A61B2090/376 , A61N5/1049 , A61N5/1077 , A61N2005/1054 , A61N2005/1061 , A61N2005/1062
摘要： An apparatus and method of localization of a target using in vivo markers is described. The method may include adjusting a position of a target volume within the body relative to a treatment beam using the in vivo markers.
摘要翻译：描述了使用体内标记定位靶的装置和方法。该方法可以包括使用体内标记物相对于治疗束来调整体内目标体积的位置。

93. 发明申请

WO2005024721A2 2D/3D IMAGE REGISTRATION IN IMAGE-GUIDED RADIOSURGERY 审中-公开
标题翻译：图像导向放射治疗中的2D / 3D图像注册
公开(公告)号：WO2005024721A2
公开(公告)日：2005-03-17
申请号：PCT/US2004/027158
申请日：2004-08-20
申请人： ACCURAY, INC. , KUDUVALLI, Gopinath , FU, Dongshan , QURESHI, Shehrzad
发明人： KUDUVALLI, Gopinath , FU, Dongshan , QURESHI, Shehrzad
IPC分类号： G06T
CPC分类号： A61N5/1049 , A61N5/1067 , A61N5/107 , A61N2005/1061 , A61N2005/1062 , G01N23/04 , G06T7/254 , G06T7/32 , G06T7/38 , G06T2207/10124 , G06T2207/30004
摘要： An image-guided radiosurgery method and system are presented that use 2D/3D image registration to keep the radiosurgical beams properly focused onto a treatment target. A pre-treatment 3D scan of the target is generated at or near treatment planning time. A set of 2D DRRs are generated, based on the pretreatment 3D scan. At least one 2D x-ray image of the target is generated in near real time during treatment. The DRRs are registered with the x-ray images, by computing a set of 3D transformation parameters that represent the change in target position between the 3D scan and the x-ray images. The relative position of the radiosurgical beams and the target is continuously adjusted in near real time in accordance with the 3D transformation parameters. A hierarchical and iterative 2D/3D registration algorithm is used, in which the transformation parameters that are in-plane with respect to the image plane of the x-ray images are computed separately from the out-of-plane transformation parameters.
摘要翻译：提出了一种使用2D / 3D图像配准的图像引导放射外科手术方法和系统，将放射外科手术束适当地聚焦到治疗目标上。在治疗计划时间或附近产生目标的预处理3D扫描。基于预处理3D扫描生成一组2D DRR。在治疗期间，近乎实时地产生目标的至少一个2D X射线图像。通过计算表示3D扫描和X射线图像之间的目标位置的变化的一组3D变换参数，向X射线图像登记DRR。根据3D变换参数，放射外科手术束和目标物的相对位置以近实时的方式连续调整。使用分层和迭代的2D / 3D注册算法，其中相对于x射线图像的像面在平面内的变换参数与面外变换参数分开计算。

94. 发明申请

WO2005018735A2 MODULAR PATIENT SUPPORT SYSTEM 审中-公开
标题翻译：模块化患者支持系统
公开(公告)号：WO2005018735A2
公开(公告)日：2005-03-03
申请号：PCT/US2004/026113
申请日：2004-08-12
申请人： LOMA LINDA UNIVERSITY MEDICAL CENTER
发明人： RIGNEY, Nick , ANDERSON, Dan , LESYNA, David , MILLER, Dan , MOYERS, Michael , CHENG, Chieh , BAUMANN, Mike , MCALLASTER, Steven , SLATER, Jerry
IPC分类号： A61N
CPC分类号： A61N5/107 , A61B6/0442 , A61B6/4092 , A61B6/547 , A61B2090/3937 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/1078 , A61N2005/105 , A61N2005/1059 , A61N2005/1061 , A61N2005/1062 , A61N2005/1087 , A61N2005/1097 , B25J9/1666 , G05B15/02 , G05B2219/45117
摘要： A radiation treatment system (100) for accurately delivering radiation to a targeted site within a cancer patient (108) that includes a modular patient support system and a patient positioner (114). The modular patient support system includes a modularly expandable patient pod (200) and at least one immobilization device, such as, for example, a rigid moldable foam cradle (350). The patient pod (200) includes a generally hemi-cylindrical support shell (212) that extends longitudinally between proximal edge (214) and distal edge (216), and transversely between two lateral edges (222, 224). In one embodiment, the lateral edges (222, 224) are tapered to minimize edge effects that result when radiation beams traverse the lateral edges (222, 224).
摘要翻译： 1.一种辐射治疗系统（100），用于将辐射准确地传送到癌症患者（108）内的目标部位，其包括模块化患者支撑系统和患者定位器（114）。模块化患者支撑系统包括模块化可扩展的患者支架（200）和至少一个固定装置，例如刚性可模制泡沫支架（350）。患者荚（200）包括在近端边缘（214）和远端边缘（216）之间纵向延伸且横向于两个横向边缘（222,224）之间延伸的大致半圆柱形的支撑壳体（212）。在一个实施例中，横向边缘（222,224）是锥形的，以最小化当辐射束横穿横向边缘（222,224）时产生的边缘效应。

95. 发明申请

WO1998018523A1 PROTON BEAM DIGITAL IMAGING SYSTEM 审中-公开
标题翻译：原子光束数字成像系统
公开(公告)号：WO1998018523A1
公开(公告)日：1998-05-07
申请号：PCT/US1997019236
申请日：1997-10-27
申请人： LOMA LINDA UNIVERSITY MEDICAL CENTER
发明人： LOMA LINDA UNIVERSITY MEDICAL CENTER , BLAIR, Mark, S. , LESYNA, David, A. , LIN, Pengyue, James , SAMANTARAI, Jagadish, P. , YELDELL, Berry, B.
IPC分类号： A61N05/10
CPC分类号： A61N5/1049 , A61N5/1069 , A61N2005/1061 , A61N2005/1062 , A61N2005/1087
摘要： A proton beam digital imaging system comprising an X-ray source which is movable into the treatment beam line that can produce an X-ray beam through a region of the patient. An X-ray receiver receives the X-ray beam after it has passed through the patient and the X-ray receiver generates photons that correspond to the X-ray image. The photons are directed to a TEC CCD camera to produce a patient orientation image which displays the orientation of the center of the beam relative to selected monuments in the patient's skeletal structure. The system also receives a master prescription image which displays the target isocenter with respect to the same selected monuments of the patient's skeletal structure. By comparison of the relative positions of the center of the beam in the patient orientation image and the isocenter in the master prescription image with respect to the selected monuments, the amount and direction of movement of the patient to make the beam center correspond to the target isocenter is determined.
摘要翻译：一种质子束数字成像系统，包括可移动到治疗束线中的X射线源，X射线源可以通过患者的区域产生X射线束。 X射线接收器在穿过患者之后接收X射线束，并且X射线接收器产生对应于X射线图像的光子。光子被引导到TEC CCD照相机以产生患者取向图像，其显示相对于患者骨骼结构中的选定纪念碑的光束中心的取向。该系统还接收相对于患者骨骼结构的相同选定纪念碑显示目标等角点的主处方图像。通过比较患者取向图像中的光束中心与主处方图像中的等中心相对于所选择的纪念碑的相对位置，使患者的移动量和方向使得束中心对应于目标确定等角点。

96. 发明申请

WO1990011721A1 PATIENT ALIGNMENT SYSTEM AND PROCEDURE FOR RADIATION TREATMENT 审中-公开
标题翻译：患者对照系统和放射治疗程序
公开(公告)号：WO1990011721A1
公开(公告)日：1990-10-18
申请号：PCT/US1990001763
申请日：1990-03-30
申请人： LOMA LINDA UNIVERSITY MEDICAL CENTER
发明人： LOMA LINDA UNIVERSITY MEDICAL CENTER , MILLER, Daniel, W. , SLATER, James, M.
IPC分类号： A61B06/03
CPC分类号： A61B6/08 , A61B2090/101 , A61N5/1048 , A61N5/1049 , A61N5/1069 , A61N2005/1061 , A61N2005/1062 , A61N2005/1087 , A61N2005/1097
摘要： Accurate and repeatable patient alignment with a charged-particle beam of a radiation beam therapy system, such as a proton beam delivery system, is provided. The patient (26) is immobilized within a formfit patient pod (24). Reference radiographs are prepared with an X-ray system (40) that are used for repositioning the patient within the pod on subsequent occasions. CT scan data is obtained using a CT Scan System (44) of a particular tissue volume of interest (30), such as a region of the patient wherein a cancerous tumor is located, while the patient (26) remains in the pod (24). The CT scan data is used to prepare a treatment plan for the patient. The treatment plan includes identifying an isocenter within the tissue volume at which the beam is to be directed from a selected angle(s). A computer simulation of the treatment plan is performed to optimize the treatment plan.

97. 发明公开

EP3407791A1 PRESENTING A SEQUENCE OF IMAGES ASSOCIATED WITH A MOTION MODEL 审中-公开
公开(公告)号：EP3407791A1
公开(公告)日：2018-12-05
申请号：EP17703006.1
申请日：2017-01-18
申请人： Accuray Incorporated
发明人： LUGOSI, Kolos , NETHERY-PAVELCHAK, Kyle , CORE, Matthew , MAURER, Calvin , JORDAN, Petr
IPC分类号： A61B6/00 , A61N5/10 , G06T7/246 , G06T7/38 , G06T19/20 , G06T17/00
CPC分类号： A61N5/1049 , A61B5/0816 , A61B5/1127 , A61B5/113 , A61B6/022 , A61B6/032 , A61B6/12 , A61B6/4014 , A61B6/4085 , A61B6/4266 , A61B6/4464 , A61B6/463 , A61B6/465 , A61B6/5223 , A61B6/5235 , A61B6/5288 , A61B6/5294 , A61B34/25 , A61B2034/107 , A61B2034/2055 , A61B2034/254 , A61B2090/364 , A61B2090/376 , A61B2090/3945 , A61B2090/3966 , A61N5/1037 , A61N5/1067 , A61N5/1083 , A61N2005/1051 , A61N2005/1061 , A61N2005/1062 , A61N2005/1074 , G06F19/00 , G06F19/3418 , G06T7/0016 , G06T7/20 , G06T7/251 , G06T7/38 , G06T11/008 , G06T17/00 , G06T19/00 , G06T19/20 , G06T2200/08 , G06T2207/10124 , G06T2207/20096 , G06T2210/41 , G06T2211/428 , G16H30/40 , G16H40/63
摘要： Images that are associated with an identification of a tracking target of a patient to receive radiation treatment may be received. The images may be sorted into a sequence based on a motion of the patient. The sorted images may be provided via a graphical user interface. The sequence of the sorted images that are based on the motion of the patient may be provided.

98. 发明授权

EP2873438B1 X-RAY POSITIONING APPARATUS AND X-RAY POSITIONING METHOD 有权
公开(公告)号：EP2873438B1
公开(公告)日：2018-10-10
申请号：EP12880734.4
申请日：2012-07-13
申请人： Mitsubishi Electric Corporation
发明人： TSUNOO Takanori , INA Nobuhiko
IPC分类号： A61N5/10
CPC分类号： A61N5/107 , A61B5/0873 , A61B5/0878 , A61B5/1135 , A61B6/0457 , A61B6/486 , A61B6/5235 , A61B6/54 , A61B6/541 , A61B2034/2055 , A61B2090/376 , A61N5/10 , A61N5/1048 , A61N5/1049 , A61N5/1068 , A61N5/1069 , A61N2005/105 , A61N2005/1051 , A61N2005/1056 , A61N2005/1059 , A61N2005/1061 , A61N2005/1062 , A61N2005/1087 , F04C2270/041 , G06F19/00
摘要： The object of the present invention is to obtain an X-ray positioning apparatus that can perform efficient photographing in accordance with a state of a respiratory waveform when a patient of radiation therapy is positioned. An X-ray positioning apparatus (20) according to the present invention is provided with an X-ray video device (3) that generates second X-ray image data (data2) in which a respiratory signal (sig1) of a patient (45) and first X-ray image data (data1) are related to each other, a positioning computer (1) that generates patient platform control data (cdata1) for controlling a patient platform (12), and a photographing trigger generation apparatus (2) that outputs a photographing trigger signal (sig3) to an X-ray tube (6); the X-ray positioning apparatus (20) is characterized in that the photographing trigger generation apparatus (2) generates the photographing trigger signal (sig3), in accordance with a first frame rate (fr1) and a second frame rate (fr2) that is higher than the first frame rate (fr1), and in that the positioning computer (1) generates the patient platform control data (cdata1), based on a reference image and one X-ray image selected from consecutively photographed images (29) that are photographed at the second frame rate (fr2).

99. 发明授权

EP2943929B1 CBCT AND X-RAY COMBINED SETUP WITH X-RAY VERIFICATION OF PATIENT POSITIONING 有权
公开(公告)号：EP2943929B1
公开(公告)日：2018-06-13
申请号：EP13700850.4
申请日：2013-01-09
申请人： Brainlab AG
发明人： BERLINGER, Kajetan , KNORR, Sebastian , SCHLOSSBAUER, Cornel , REHS, Jörg
IPC分类号： A61B6/03 , A61B6/04 , A61B6/00 , A61N5/10 , G06T7/00 , G06T7/30
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/04 , A61B6/4085 , A61N5/1037 , A61N5/107 , A61N5/1071 , A61N5/1077 , A61N2005/1061 , A61N2005/1062 , A61N2005/1072 , A61N2005/1074 , G06T7/0012 , G06T7/30 , G06T2207/10072
摘要： The invention is directed to a data processing method for determining the consistency of registration of the position of a treatment body part to be treated by radiotherapy with a treatment beam arrangement of at least one position of a treatment beam issued by a treatment device, the treatment body part being a soft tissue part of an anatomical structure of a patient's body and the data processing method being constituted to be executed by a computer and comprising the following steps: g) acquiring CT data comprising predetermined CT information about a position of the treatment body part relative to a bony structure of the patient's body and about a first position of the bony structure relative to the treatment beam arrangement; h) acquiring x-ray data comprising x-ray information about a second position of the bony structure relative to the treatment beam arrangement; i) determining, based on the x-ray data and the CT data, bony structure position first transformation data comprising bony structure position first transformation information about a first transformation between the first position and the second position of the bony structure; j) acquiring CBCT data comprising CBCT information about the position of the treatment body part relative to the treatment beam arrangement or relative to the bony structure; k) determining, based on the CBCT data and the CT data, bony structure position second transformation data comprising bony structure position second transformation information about a second transformation between the first position and a third position of the bony structure relative to the treatment beam arrangement; determining, based on the bony structure position first transformation data and the bony structure position second transformation data, transformation difference data comprising transformation difference information about a difference between the first and second transformations.

100. 发明授权

EP2665519B1 RADIATION TREATMENT DELIVERY SYSTEM WITH RING GANTRY 有权
标题翻译：环带机舱的辐射处理输送系统
公开(公告)号：EP2665519B1
公开(公告)日：2017-12-20
申请号：EP12700904.1
申请日：2012-01-10
申请人： Accuray Incorporated
发明人： MAURER, Calvin R. JR. , LINDQUIST, Eric P.
IPC分类号： A61N5/10 , A61N5/00
CPC分类号： A61B6/032 , A61B5/055 , A61B6/4085 , A61B6/4405 , A61N5/10 , A61N5/1045 , A61N5/1048 , A61N5/1049 , A61N5/1067 , A61N5/1081 , A61N5/1082 , A61N2005/0633 , A61N2005/1055 , A61N2005/1061 , A61N2005/1062 , A61N2005/1063
摘要： Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. For one preferred embodiment, an IGRT apparatus is provided comprising a ring gantry having a central opening and a radiation treatment head coupled to the ring gantry that is rotatable around the central opening in at least a 180 degree arc. For one preferred embodiment, the apparatus further comprises a gantry translation mechanism configured to translate the ring gantry in a direction of a longitudinal axis extending through the central opening. Noncoplanar radiation treatment delivery can thereby be achieved without requiring movement of the patient. For another preferred embodiment, an independently translatable 3D imaging device distinct from the ring gantry is provided for further achieving at least one of pre-treatment imaging and setup imaging of the target tissue volume without requiring movement of the patient.

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