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    • 95. 发明授权
    • Process for producing cellulosic dialysis membranes having improved
biocompatibility and device for carrying out the process
    • 用于生产具有改进的生物相容性的纤维素透析膜的方法和用于进行该方法的装置
    • US4962140A
    • 1990-10-09
    • US344967
    • 1989-04-28
    • Michael Diamantoglou
    • Michael Diamantoglou
    • A61M1/18A61L33/00B01D67/00B01D71/08B01D71/12C08B3/20C08B15/06C08B37/08
    • B01D67/0093A61L33/0082B01D71/08B01D71/12C08B15/06C08B37/003
    • The invention relates to an apparatus and process for the chemical modification of cellulosic dialysis membranes, wherein solutions of acid chlorides, acid anhydrides, esters, ketenes, diketenes, chlorocarbolic acid esters, carbonic acid diesters, 2,5-diketooxazolidines, isatinic anhydride, isocyanates, carbamoyl chlorides, thiocyanates, thiocarbamoyl chlorides, sulfonyl chlorides, sulfonic acid anhydrides, N-chlorosulfonamides, sulfinic acid chlorides, N-chlorosulfinamides, phosphoric acid anhydride, phosphonic anhydrides, phosphonic acid chlorides, phosphorous acid, phosphinic acid anydrides, ethylene oxide, ethylene sulfide, ethyleneimino, lactone, sultone and/or cleavable onium compounds, alkylaminoethanol sulfate esters, alkylsulfonethanol sulfate esters, vinylsulfonic acid or a salt thereof, vinylsulfonic acid ester, vinylphosphonic acid or a salt thereof, vinylphosphonic acid esters, allylsulfonic acid or a salt thereof, allysulfonic acid esters, allylphosphonic acid or a salt thereof, allyphosphonic acid esters, acrylamide, methacrylamide, acrylic acids or a salt thereof, acrylic acid ester, methacrylic acid or a salt thereof, methacrylic acid esters, acrylonitrile, crotonic acid or a salt thereof and/or crotonic acid ester and/or crotonic acid nitrile in polar solvents, if necessary together with the catalysts and auxiliary substances necessary for the reaction, are passed over one surface of the dialysis membrane.
    • 本发明涉及纤维素透析膜的化学改性的装置和方法,其中酰氯,酸酐,酯,烯酮,双烯酮,氯代羧酸酯,碳酸二酯,2,5-二酮恶唑烷,靛红酸酐,异氰酸酯 ,氨基甲酰氯,硫氰酸酯,硫代氨基甲酰氯,磺酰氯,磺酸酐,N-氯磺酰胺,亚磺酰氯,N-氯亚磺酰胺,磷酸酐,膦酸酐,膦酸氯化物,亚磷酸,次膦酸酐,环氧乙烷,乙烯 硫化物,乙烯亚氨基,内酯,磺内酯和/或可裂解的鎓化合物,烷基氨基乙醇硫酸酯,烷基磺基乙醇硫酸酯,乙烯基磺酸或其盐,乙烯基磺酸酯,乙烯基膦酸或其盐,乙烯基膦酸酯,烯丙基磺酸或其盐 ,烯丙基磺酸酯,烯丙基膦酸或盐 丙烯酸酯,甲基丙烯酸或其盐,甲基丙烯酸酯,丙烯腈,巴豆酸或其盐和/或巴豆酸酯和/或巴豆酸 极性溶剂中的酸性腈如果需要,与反应所需的催化剂和辅助物质一起通过透析膜的一个表面。