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11. 发明申请

WO2003083082A3 ENZYMES 审中-公开
公开(公告)号：WO2003083082A3
公开(公告)日：2003-10-09
申请号：PCT/US2003/009772
申请日：2003-03-26
申请人： INCYTE CORPORATION , TRAN, Uyen, K. , KABLE, Amy, E. , RAMKUMAR, Jayalaxmi , ISON, Craig, H. , RICHARDSON, Thomas, W. , LEE, Soo, Y. , KHARE, Reena , MARQUIS, Joseph, P. , SWARNAKAR, Anita , CHAWLA, Narinder, K. , ELLIOTT, Vicki, S. , EMERLING, Brooke, M. , BECHA, Shanya, D. , HAFALIA, April, J.A. , LI, Joana, X. , GRIFFIN, Jennifer, A. , HAWKINS, Phillip, R. , JIN, Pei , CHIEN, David , JIANG, Xin , JACKSON, Alan, A. , MASON, Patricia, M. , BHATIA, Umesh, G. , BURRILL, John, D. , LEE, Sally , BLAKE, Julie, J. , HO, Anne , ZHENG, Wenjin , GAO, Jing
发明人： TRAN, Uyen, K. , KABLE, Amy, E. , RAMKUMAR, Jayalaxmi , ISON, Craig, H. , RICHARDSON, Thomas, W. , LEE, Soo, Y. , KHARE, Reena , MARQUIS, Joseph, P. , SWARNAKAR, Anita , CHAWLA, Narinder, K. , ELLIOTT, Vicki, S. , EMERLING, Brooke, M. , BECHA, Shanya, D. , HAFALIA, April, J.A. , LI, Joana, X. , GRIFFIN, Jennifer, A. , HAWKINS, Phillip, R. , JIN, Pei , CHIEN, David , JIANG, Xin , JACKSON, Alan, A. , MASON, Patricia, M. , BHATIA, Umesh, G. , BURRILL, John, D. , LEE, Sally , BLAKE, Julie, J. , HO, Anne , ZHENG, Wenjin , GAO, Jing
IPC分类号： C12N9/10
摘要： Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.

13. 发明申请

WO2003072723A3 INTRACELLULAR SIGNALING MOLECULES 审中-公开
公开(公告)号：WO2003072723A3
公开(公告)日：2003-09-04
申请号：PCT/US2003/005336
申请日：2003-02-19
申请人： INCYTE CORPORATION , YUE, Henry , BANDMAN, Olga , RICHARDSON, Thomas, W. , GRIFFIN, Jennifer, A. , EMERLING, Brooke, M. , KABLE, Amy, E. , LEE, Sally , BARROSO, Ines , HAFALIA, April, J.A. , FORSYTHE, Ian, J. , HAWKINS, Phillip, R. , JIN, Pei , RAMKUMAR, Jayalaxmi , KHARE, Reena , ELLIOTT, Vicki, S. , BECHA, Shanya, D. , SWARNAKAR, Anita , MARQUIS, Joseph, P. , TANG, Y. , Tom , BAUGHN, Mariah, R. , WARREN, Bridget, A. , LI, Joana, X. , ZEBARJADIAN, Yeganeh , GIETZEN, Kimberly, J. , CHAWLA, Narinder, K. , BULLOCH, Sean, A. , BURFORD, Neil , YAO, Monique, G. , LEE, Soo, Yeun , LEE, Ernestine, A. , LEHR-MASON, Patricia, M.
发明人： YUE, Henry , BANDMAN, Olga , RICHARDSON, Thomas, W. , GRIFFIN, Jennifer, A. , EMERLING, Brooke, M. , KABLE, Amy, E. , LEE, Sally , BARROSO, Ines , HAFALIA, April, J.A. , FORSYTHE, Ian, J. , HAWKINS, Phillip, R. , JIN, Pei , RAMKUMAR, Jayalaxmi , KHARE, Reena , ELLIOTT, Vicki, S. , BECHA, Shanya, D. , SWARNAKAR, Anita , MARQUIS, Joseph, P. , TANG, Y. , Tom , BAUGHN, Mariah, R. , WARREN, Bridget, A. , LI, Joana, X. , ZEBARJADIAN, Yeganeh , GIETZEN, Kimberly, J. , CHAWLA, Narinder, K. , BULLOCH, Sean, A. , BURFORD, Neil , YAO, Monique, G. , LEE, Soo, Yeun , LEE, Ernestine, A. , LEHR-MASON, Patricia, M.
IPC分类号： C12P21/06
摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.

14. 发明申请

WO2009065088A2 SOLAR-POWERED HEADSET 审中-公开
标题翻译：太阳能头戴式耳机
公开(公告)号：WO2009065088A2
公开(公告)日：2009-05-22
申请号：PCT/US2008/083701
申请日：2008-11-14
申请人： BETTER ENERGY SYSTEMS LTD , FOWLER, David
发明人： FOWLER, David
IPC分类号： H04R1/10 , H02J7/35 , H04B1/38
CPC分类号： H04M1/6066 , H02S20/00 , H04M1/0243 , Y02E10/50
摘要： A solar-powered device includes a housing including an electronic element, a number of panels having solar cells capable of providing electrical energy upon illumination, the panels being configured to move from a closed configuration to an open configuration, where the open configuration allows illumination to fall upon the solar cells when positioned in a location from which illumination is available; and a support element contacting the panels and the housing to convey electricity from the panels to the housing, where the electronic elements are powered with electricity from the solar cells.
摘要翻译：太阳能设备包括具有电子元件的外壳，具有能够在照明时提供电能的太阳能电池的多个面板，所述面板被配置为从闭合构造移动到打开构造其中当位于可用照明的位置时，打开配置允许照明落在太阳能电池上; 以及与面板和外壳接触的支撑元件，以将电能从面板传送到外壳，其中电子元件由来自太阳能电池的电力供电。

15. 发明申请

WO2009032319A1 CALIBRATED RPMA ASSAY 审中-公开
标题翻译：校准RPMA测定
公开(公告)号：WO2009032319A1
公开(公告)日：2009-03-12
申请号：PCT/US2008/010445
申请日：2008-09-05
申请人： PETRICOIN III, Emanuel F. , LIOTTA, Lance A.
发明人： PETRICOIN III, Emanuel F. , LIOTTA, Lance A.
IPC分类号： G01N33/96 , G01N33/53
CPC分类号： G01N33/96 , G01N33/5005
摘要： This invention relates, e.g., to a set of calibrants for determining the amount in a sample of an analyte (e.g., a protein, such as a protein that has been post-translationally modified), comprising a plurality of calibrants, which contain a range of amounts (e.g., defined amounts and/or serial dilutions) of the analyte, spanning the expected amount of the analyte in the sample. In each of the calibrants, a defined amount of the analyte is present in the same suitable, biological diluent (e.g., a cell or tissue lysate, or a bodily fluid). In one embodiment of the invention, the diluent reflects the same or a similar biological milieu (proteins, lipids, serum proteins, serum matrix proteins, etc.) as that in the sample in which the analyte to be measured is present. In embodiments of the invention, a single calibrant (e.g., a cell lysate) may comprise as many as hundreds of analytes, and can be used for the quantification of those hundreds of analytes in a sample. Methods are described for performing an assay (e.g. RPMA analysis), in which the calibrants of a set of calibrants of the invention are immobilized on each of the surfaces to which samples to be analyzed are immobilized, thereby providing an internal calibration curve for quantifying an RPMA assay.
摘要翻译：本发明涉及例如用于确定分析物样品中的量（例如蛋白质，例如经翻译后修饰的蛋白质）的一组校准剂，其包含多个校准物，其包含范围的分析物的量（例如，定义的量和/或连续稀释度），跨越样品中分析物的预期量。在每个校准中，一定量的分析物存在于相同的合适的生物稀释剂（例如，细胞或组织裂解液或体液）中。在本发明的一个实施方案中，稀释剂反映与待测分析物存在的样品中相同或相似的生物环境（蛋白质，脂质，血清蛋白，血清基质蛋白等）。在本发明的实施方案中，单个校准物（例如，细胞裂解物）可以包含多达数百种分析物，并且可以用于量化样品中数百种分析物。描述了用于进行测定（例如RPMA分析）的方法，其中本发明的一组校准剂的校准物被固定在待分析样品固定的每个表面上，由此提供内部校准曲线，用于量化 RPMA测定。

16. 发明申请

WO2003104410A3 ENZYMES 审中-公开
公开(公告)号：WO2003104410A3
公开(公告)日：2003-12-18
申请号：PCT/US2003/017907
申请日：2003-06-05
申请人： INCYTE CORPORATION , LEE, Soo, Y. , KABLE, Amy, E. , CHAWLA, Narinder, K. , MASON, Patricia, M. , HAFALIA, April, J.A. , MARQUIS, Joseph, P. , RICHARDSON, Thomas, W. , ELLIOTT, Vicki, S. , BECHA, Shanya, D. , BULLOCH, Sean, A. , HAWKINS, Phillip, R. , JIN, Pei , GIETZEN, Kimberly, J. , WILSON, Amy, D. , CHANG, Hsin-Ru , KHARE, Reena , SWARNAKAR, Anita , TRAN, Uyen, K. , EMERLING, Brooke, M.
发明人： LEE, Soo, Y. , KABLE, Amy, E. , CHAWLA, Narinder, K. , MASON, Patricia, M. , HAFALIA, April, J.A. , MARQUIS, Joseph, P. , RICHARDSON, Thomas, W. , ELLIOTT, Vicki, S. , BECHA, Shanya, D. , BULLOCH, Sean, A. , HAWKINS, Phillip, R. , JIN, Pei , GIETZEN, Kimberly, J. , WILSON, Amy, D. , CHANG, Hsin-Ru , KHARE, Reena , SWARNAKAR, Anita , TRAN, Uyen, K. , EMERLING, Brooke, M.
IPC分类号： C12N9/10
摘要： Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.

17. 发明申请

WO2003095622A3 PROTEINS ASSOCIATED WITH CELL GROWTH, DIFFERENTIATION, AND DEATH 审中-公开
公开(公告)号：WO2003095622A3
公开(公告)日：2003-11-20
申请号：PCT/US2003/014742
申请日：2003-05-08
申请人： INCYTE CORPORATION , KABLE, Amy, E. , ELLIOTT, Vicki, S. , KHARE, Reena , BULLOCH, Sean, A. , LEE, Soo Yeun , BECHA, Shanya, D. , CHAWLA, Narinder, K. , TANG, Y. , Tom , YUE, Henry , BAUGHN, Mariah, R. , TRAN, Uyen, K. , KAREHT, Stephanie, K. , EMERLING, Brooke, M. , GRIFFIN, Jennifer, A. , SWARNAKAR, Anita , CHANG, Hsin-Ru , RAMKUMAR, Jayalaxmi , RICHARDSON, Thomas, W. , MARQUIS, Joseph, P.
发明人： KABLE, Amy, E. , ELLIOTT, Vicki, S. , KHARE, Reena , BULLOCH, Sean, A. , LEE, Soo Yeun , BECHA, Shanya, D. , CHAWLA, Narinder, K. , TANG, Y. , Tom , YUE, Henry , BAUGHN, Mariah, R. , TRAN, Uyen, K. , KAREHT, Stephanie, K. , EMERLING, Brooke, M. , GRIFFIN, Jennifer, A. , SWARNAKAR, Anita , CHANG, Hsin-Ru , RAMKUMAR, Jayalaxmi , RICHARDSON, Thomas, W. , MARQUIS, Joseph, P.
IPC分类号： A61K38/00 , C07H21/02
摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.

18. 发明申请

WO2003094843A3 CELL ADHESION AND EXTRACELLULAR MATRIX PROTEINS 审中-公开
公开(公告)号：WO2003094843A3
公开(公告)日：2003-11-20
申请号：PCT/US2003/014076
申请日：2003-05-06
申请人： INCYTE CORPORATION , KHARE, Reena , ELLIOTT, Vicki, S. , MARQUIS, Joseph, P. , RAMKUMAR, Jayalaxmi , CHAWLA, Narinder, K. , MASON, Patricia, M. , HAFALIA, April, J.A. , SWARNAKAR, Anita , JIN, Pei , BECHA, Shanya, D. , KABLE, Amy, E. , TRAN, Uyen, K. , BAUGHN, Mariah, R. , BURFORD, Neil , GRAUL, Richard, C. , EMERLING, Brooke, M. , SPRAGUE, William, W. , GRIFFIN, Jennifer, A. , ISON, Craig, H.
发明人： KHARE, Reena , ELLIOTT, Vicki, S. , MARQUIS, Joseph, P. , RAMKUMAR, Jayalaxmi , CHAWLA, Narinder, K. , MASON, Patricia, M. , HAFALIA, April, J.A. , SWARNAKAR, Anita , JIN, Pei , BECHA, Shanya, D. , KABLE, Amy, E. , TRAN, Uyen, K. , BAUGHN, Mariah, R. , BURFORD, Neil , GRAUL, Richard, C. , EMERLING, Brooke, M. , SPRAGUE, William, W. , GRIFFIN, Jennifer, A. , ISON, Craig, H.
IPC分类号： C12Q1/68
摘要： Various embodiments of the invention provide human cell adhesion and extracellular matrix proteins (CADECM) and polynucleotides which identify and encode CADECM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CADECM.

19. 发明申请

WO2003087300A3 SECRETED PROTEINS 审中-公开
公开(公告)号：WO2003087300A3
公开(公告)日：2003-10-23
申请号：PCT/US2003/010249
申请日：2003-04-01
申请人： INCYTE CORPORATION , MARQUIS, Joseph, P. , LEE, Soo, Y. , ELLIOTT, Vicki, S. , RAMKUMAR, Jayalaxmi , HAFALIA, April, J., A. , KABLE, Amy, E. , CHAWLA, Narinder, K. , EMERLING, Brooke, M. , KHARE, Reena , JIANG, Xin , JACKSON, Alan, A. , HAWKINS, Phillip, R. , JIN, Pei , MASON, Patricia, M. , RICHARDSON, Thomas, W. , SWARNAKAR, Anita , LAL, Preeti, G. , WARREN, Bridget, A. , LEE, Sally , GRIFFIN, Jennifer, A. , FU, Glenn, K. , WILSON, Amy, D. , XU, Yuming , BULLOCH, Sean, A. , BECHA, Shanya, D. , BHATIA, Umesh, G. , BURRILL, John, D. , BLAKE, Julie, J. , HO, Anne , ZHENG, Wenjin
发明人： MARQUIS, Joseph, P. , LEE, Soo, Y. , ELLIOTT, Vicki, S. , RAMKUMAR, Jayalaxmi , HAFALIA, April, J., A. , KABLE, Amy, E. , CHAWLA, Narinder, K. , EMERLING, Brooke, M. , KHARE, Reena , JIANG, Xin , JACKSON, Alan, A. , HAWKINS, Phillip, R. , JIN, Pei , MASON, Patricia, M. , RICHARDSON, Thomas, W. , SWARNAKAR, Anita , LAL, Preeti, G. , WARREN, Bridget, A. , LEE, Sally , GRIFFIN, Jennifer, A. , FU, Glenn, K. , WILSON, Amy, D. , XU, Yuming , BULLOCH, Sean, A. , BECHA, Shanya, D. , BHATIA, Umesh, G. , BURRILL, John, D. , BLAKE, Julie, J. , HO, Anne , ZHENG, Wenjin
IPC分类号： C12P21/00 , C12N15/00 , C07K1/00
摘要： Various embodiments of the invention provide human secreted proteins (SECP)and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

20. 发明申请

WO2003083085A3 TRANSPORTERS AND ION CHANNELS 审中-公开
公开(公告)号：WO2003083085A3
公开(公告)日：2003-10-09
申请号：PCT/US2003/009797
申请日：2003-03-27
申请人： INCYTE CORPORATION , MARQUIS, Joseph, P. , LEE, Soo, Y. , EMERLING, Brooke, M. , HAFALIA, April, J.A. , KHARE, Reena , KABLE, Amy, E. , RICHARDSON, Thomas, W. , SWARNAKAR, Anita , CHAWLA, Narinder, K. , BECHA, Shanya, D. , MASON, Patricia, M. , ELLIOTT, Vicki, S. , RAMKUMAR, Jayalaxmi , GRIFFIN, Jennifer, A. , TRAN, Uyen, K. , ISON, Craig, H. , LINDQUIST, Erika, A. , JIANG, Xin , JACKSON, Alan, A. , WILSON, Amy, D. , JIN, Pei , CHANG, Hsin-Ru
发明人： MARQUIS, Joseph, P. , LEE, Soo, Y. , EMERLING, Brooke, M. , HAFALIA, April, J.A. , KHARE, Reena , KABLE, Amy, E. , RICHARDSON, Thomas, W. , SWARNAKAR, Anita , CHAWLA, Narinder, K. , BECHA, Shanya, D. , MASON, Patricia, M. , ELLIOTT, Vicki, S. , RAMKUMAR, Jayalaxmi , GRIFFIN, Jennifer, A. , TRAN, Uyen, K. , ISON, Craig, H. , LINDQUIST, Erika, A. , JIANG, Xin , JACKSON, Alan, A. , WILSON, Amy, D. , JIN, Pei , CHANG, Hsin-Ru
IPC分类号： A61K38/00 , A61K39/00 , C07H21/04 , C07K1/00 , C07K14/00 , C07K16/00 , C12N1/20 , C12N5/00 , C12N15/09 , C12P21/00
摘要： Various embodiments of the invention provide human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

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