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    • 24. 发明申请
    • LIGHT DIFFUSER AND PROCESS FOR PRODUCING THE SAME
    • 光扩散器及其制造方法
    • US20090318912A1
    • 2009-12-24
    • US12487085
    • 2009-06-18
    • Jörg MayerMarcel AeschlimannLaurent TorrianiHeinrich Walt
    • Jörg MayerMarcel AeschlimannLaurent TorrianiHeinrich Walt
    • A61B18/18
    • A61B18/20A61B2018/2261
    • A light diffuser (10), which is particularly suitable for introducing diffuse light into a tissue, is produced by interpenetration of a diffuser material in a liquid state into a boundary layer (4) of a porous shaping material, by which process a diffuser surface is formed having a surface structure which represents essentially a negative of the pore structure of the shaping material and includes undercut structures induced by a surface tension. The light diffuser (10) is e.g. produced by introducing a diffuser blank (1) including material which is liquefiable through mechanical vibration into the shaping material and simultaneously stimulating it with mechanical vibrations, such that the liquefiable material liquefies at least there where it is in contact with the shaping material and is pressed into the shaping material. An in situ production of the diffuser is particularly advantageous for photodynamic therapy in bone tissue (20).
    • 特别适于将漫射光引入组织中的光扩散器(10)通过将液态的漫射材料相互渗透到多孔成形材料的边界层(4)中来产生,通过该扩散器,扩散器表面 形成有表面结构,其表示成形材料的孔结构的基本上为负的,并且包括由表面张力引起的底切结构。 光扩散器(10) 通过将包括通过机械振动可液化的材料的扩散器坯料(1)引入到成型材料中并同时用机械振动刺激它,使得液化材料至少在其与成型材料接触的地方液化并被压制 成型材料。 扩散器的原位生产对于骨组织中的光动力学治疗特别有利(20)。
    • 29. 发明申请
    • Method for promoting tissue regeneration on wound surfaces as device and treatment instrument or implant for carrying out method
    • 促进伤口表面组织再生的方法,作为装置和治疗仪器或植入物进行方法
    • US20060122543A1
    • 2006-06-08
    • US10528867
    • 2004-07-29
    • Jorg MayerChristopher RastMarcel AeschlimannLaurent Torriani
    • Jorg MayerChristopher RastMarcel AeschlimannLaurent Torriani
    • A61H7/00
    • A61C1/07A61B17/1659A61B17/8875A61B2017/320078A61B2017/320089A61C3/03A61C8/00A61C8/0018A61C17/20A61N7/00
    • For promoting tissue regeneration on wound surfaces (1) mechanical oscillation is coupled into the wound surfaces. A treatment instrument (2) coupled to an oscillation drive is brought into contact with the wound surface (1), or an implant is impinged with oscillation during and/or after being positioned in the tissue. The oscillation acts mechanically and thermally on the tissue in the region of the treated wound surface (1), and according to the intensity acts in a stimulating, traumatic, necrotic or cell-destroying manner. Therefore, biological elements inhibiting tissue regeneration are destroyed or denatured and the metabolism in the region of the wound surface is stimulated. The effect may also be a mechanical one, slightly compacting or regionally dislocating the tissue. Since the treatment can be effected during or after positioning an implant, necrosis in particular effects undesired cells, such as connective tissue cells, mucous cells and diseased cells having been brought to the wound surface with the implant, which cells may inhibit the intergrowth between tissue and implant.
    • 为了促进伤口表面上的组织再生(1)机械振动被耦合到伤口表面。 耦合到振荡驱动器的治疗仪器(2)与伤口表面(1)接触,或者植入物在定位在组织期间和/或之后被冲击。 振荡在经处理的伤口表面(1)的区域上对组织进行机械和热作用,并且根据强度以刺激,创伤,坏死或细胞破坏的方式起作用。 因此,抑制组织再生的生物元素被破坏或变性,并且刺激伤口表面区域的新陈代谢。 该效果还可以是机械的,稍微压实或区域性地使组织脱位。 由于治疗可以在植入物定位期间或之后实现,所以坏死特别地影响已经用植入物带到伤口表面的不想要的细胞,例如结缔组织细胞,粘液细胞和患病细胞,这些细胞可以抑制组织之间的共生 和植入物。