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21. 发明申请

WO2012024581A3 OXYSTEROL COMPOUNDS 审中-公开
标题翻译： OXYSTEROL化合物
公开(公告)号：WO2012024581A3
公开(公告)日：2012-04-12
申请号：PCT/US2011048414
申请日：2011-08-19
申请人： FATE THERAPEUTICS INC , EPPERSON MATT , FAROUZ FRANCINE , STAPPENBECK FRANK , XIAO WEI
发明人： EPPERSON MATT , FAROUZ FRANCINE , STAPPENBECK FRANK , XIAO WEI
IPC分类号： C07J7/00 , A61K31/575 , A61P3/04 , A61P9/10 , A61P17/14 , A61P19/08 , A61P19/10
CPC分类号： A61K45/06 , A61K33/16 , A61K38/1841 , A61K38/1875 , A61K38/29 , A61K38/30 , C07J9/00 , C07J51/00 , A61K2300/00
摘要： Compounds for use in the treatment of bone disorders, obesity, cardiovascular disorders and neurological disorders are disclosed. The compounds have the following structure (I) including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Z, E, R1 and q are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
摘要翻译：公开了用于治疗骨疾病，肥胖症，心血管疾病和神经疾病的化合物。所述化合物具有以下结构（I），包括其立体异构体，药学上可接受的盐和前药，其中X，Z，E，R 1和q如本文所定义。还公开了与这些化合物的制备和使用有关的方法，以及包含这些化合物的药物组合物。

22. 发明申请

WO2012024581A2 OXYSTEROL COMPOUNDS 审中-公开
标题翻译：毒素化合物
公开(公告)号：WO2012024581A2
公开(公告)日：2012-02-23
申请号：PCT/US2011/048414
申请日：2011-08-19
申请人： FATE THERAPEUTICS, INC. , EPPERSON, Matt , FAROUZ, Francine , STAPPENBECK, Frank , XIAO, Wei
发明人： EPPERSON, Matt , FAROUZ, Francine , STAPPENBECK, Frank , XIAO, Wei
IPC分类号： A61K31/58
CPC分类号： A61K45/06 , A61K33/16 , A61K38/1841 , A61K38/1875 , A61K38/29 , A61K38/30 , C07J9/00 , C07J51/00 , A61K2300/00
摘要： Compounds for use in the treatment of bone disorders, obesity, cardiovascular disorders and neurological disorders are disclosed. The compounds have the following structure (I) including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Z, E, R 1 and q are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
摘要翻译：公开了用于治疗骨疾病，肥胖，心血管疾病和神经障碍的化合物。所述化合物具有以下结构（I），其包括立体异构体，其药学上可接受的盐和前药，其中X，Z，E，R 1和q如本文所定义。还公开了与这种化合物的制备和使用相关的方法以及包含这些化合物的药物组合物。

23. 发明申请

WO2010141805A1 HETEROCYCLIC AMIDES AS MODULATORS OF TRPA1 审中-公开
标题翻译：作为TRPA1的调节剂的杂环化合物
公开(公告)号：WO2010141805A1
公开(公告)日：2010-12-09
申请号：PCT/US2010/037381
申请日：2010-06-04
申请人： JANSSEN PHARMACEUTICA NV , BERTHELOT, Didier, Jean-claude , GIJSEN, Henricus Jacobus, Maria , ZAJA, Mirko , RECH, Jason , LEBSACK, Alec , XIAO, Wei , BREITENBUCHER, J., Guy , BRANSTETTER, Bryan
发明人： BERTHELOT, Didier, Jean-claude , GIJSEN, Henricus Jacobus, Maria , ZAJA, Mirko , RECH, Jason , LEBSACK, Alec , XIAO, Wei , BREITENBUCHER, J., Guy , BRANSTETTER, Bryan
IPC分类号： C07D207/48 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/12 , C07D409/14 , A61K31/506 , A61K31/401 , A61K31/4439 , A61K31/404 , A61K31/496 , A61K31/5377 , A61K31/451
CPC分类号： C07D403/14 , C07D207/48 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/12 , C07D409/14
摘要： Certain heterocyclic amide compounds are described. The compounds may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by TRPA1 activity, such as pain, arthritis, itch, cough, asthma, or inflammatory bowel disease.
摘要翻译：描述了某些杂环酰胺化合物。该化合物可用于治疗由TRPA1活性介导的疾病状态，病症和状况的药物组合物和方法，例如疼痛，关节炎，瘙痒，咳嗽，哮喘或炎症性肠病。

24. 发明申请

WO2010115352A1 TWO-DIMENSIONAL ARRAY CODE 审中-公开
标题翻译：二维阵列码
公开(公告)号：WO2010115352A1
公开(公告)日：2010-10-14
申请号：PCT/CN2010/000478
申请日：2010-04-12
申请人： GMEDIA TECHNOLOGY (BEIJING) CO., LTD. , BEIJING SIGONE VENTURE LIMITED , SHEN, Wei , LIU, Jia Bing , GUO, Xiao Wei , ZHONG, Li Duo
发明人： SHEN, Wei , LIU, Jia Bing , GUO, Xiao Wei , ZHONG, Li Duo
IPC分类号： G06K19/06
CPC分类号： G06K19/06037
摘要： The present invention relates to a two-dimensional array code. The two-dimensional array code comprises a plurality of equal-height code characters arranged into a two-dimensional array, wherein each of the code characters corresponds to a bit group representing information, and the adjacent code characters in the row direction of the two-dimensional array have equal center distances; and a locating mechanism, for defining size and/or direction of the two-dimensional array arranged by the code characters. The present invention greatly reduces the cost for issuing a two-dimensional code, and significantly increases the user convenience. This two-dimensional array code has high compatibility for user mobile terminals. In addition, the entire system apparently improves its safety and stability, and is suitable for the present network application environment.
摘要翻译：本发明涉及一种二维阵列码。二维阵列代码包括排列成二维阵列的多个等高码字符，其中每个代码字符对应于表示信息的位组，并且二维阵列代码中的相邻代码字符在二维阵列的行方向上相邻，尺寸阵列具有相等的中心距离; 以及用于定义由代码字符排列的二维阵列的大小和/或方向的定位机构。本发明大大降低了发行二维码的成本，显着提高了用户的便利性。该二维阵列码对于用户移动终端具有高兼容性。此外，整个系统显然提高了其安全性和稳定性，适合当前的网络应用环境。

25. 发明申请

WO2010057366A1 SYSTEM AND METHOD OF TRANSMITTING ELECTRONIC VOUCHER THROUGH SHORT MESSAGE 审中-公开
标题翻译：通过短信发送电子邮件的系统和方法
公开(公告)号：WO2010057366A1
公开(公告)日：2010-05-27
申请号：PCT/CN2009/001288
申请日：2009-11-20
申请人： GMEDIA TECHNOLOGY (BEIJING) CO., LTD. , BEIJIING SIGONE VENTURE LIMITED , SHEN, Wei , LIU, Jia Bing , GUO, Xiao Wei , WANG, Si Ping , AI, Feng , ZHONG, Li Duo
发明人： SHEN, Wei , LIU, Jia Bing , GUO, Xiao Wei , WANG, Si Ping , AI, Feng , ZHONG, Li Duo
IPC分类号： H04W4/14
CPC分类号： H04W4/18 , G06Q20/045 , H04L51/38 , H04W4/14
摘要： The present invention relates to system and method of transmitting electronic voucher through short message. A method of transmitting an electronic voucher through a short message comprising converting an electronic voucher to be transmitted into a bit stream; mapping each n-bits of the bit stream to any one text character of one of a plurality of text character groups, wherein text characters in each of the text character groups have at least one same or similar feature, and bit number n corresponding to each text character depends on the number m of the text character groups; arranging the text characters obtained through the mapping into a character sequence; and transmitting the character sequence through a short message. The present invention greatly reduces the cost for issuing an electronic voucher, significantly increases the convenience and apparently improves the safety and the stability.
摘要翻译：本发明涉及通过短消息传送电子凭证的系统和方法。一种通过短消息发送电子凭单的方法，包括将要发送的电子凭证转换成比特流; 将比特流的每个n比特映射到多个文本字符组之一的任何一个文本字符，其中每个文本字符组中的文本字符具有至少一个相同或相似的特征，以及对应于每个文本字符组的位号n 文本字符取决于文本字符组的数量m; 将通过映射获得的文本字符排列成字符序列; 并通过短消息发送字符序列。本发明大大降低了发行电子凭单的成本，显着增加了方便性，显然提高了安全性和稳定性。

26. 发明申请

WO2009078999A1 IMIDAZOLO-, OXAZOLO-, AND THIAZOLOPYRIMIDINE MODULATORS OF TRPV1 审中-公开
标题翻译： TRPV1的咪唑啉酮，氧杂双环和三唑基咪嗪调节剂
公开(公告)号：WO2009078999A1
公开(公告)日：2009-06-25
申请号：PCT/US2008/013808
申请日：2008-12-16
申请人： JANSSEN PHARMACEUTICA N.V. , BRANSTETTER, Bryan, James , BREITENBUCHER, J., Guy , LEBSACK, Alec, D. , LIU, Jing , RECH, Jason, C. , XIAO, Wei
发明人： BRANSTETTER, Bryan, James , BREITENBUCHER, J., Guy , LEBSACK, Alec, D. , LIU, Jing , RECH, Jason, C. , XIAO, Wei
IPC分类号： A61K31/535 , A61K31/52
CPC分类号： C07D513/04 , A61K31/497 , A61K31/519 , A61K31/5377 , C07D473/16 , C07D473/18 , C07D473/24 , C07D473/34 , C07D498/04
摘要： Certain TRPV1 -modulating imidazolo-, oxazolo-, and thiazolopyrimdine compounds are described. The compounds may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by TRPVI activity, such as pain, arthritis, itch, cough, asthma, or inflammatory bowel disease.
摘要翻译：描述了一些TRPV1调节咪唑并，恶唑并和噻唑并嘧啶化合物。这些化合物可以用于治疗由TRPVI活性介导的疾病状态，病症和状况的药物组合物和方法，例如疼痛，关节炎，瘙痒，咳嗽，哮喘或炎症性肠病。

27. 发明申请

WO2004037257A1 PHENYLPIPERIDINES AND PHENYLPYRROLIDINES AS HISTAMINE H3 RECEPTOR MODULATORS 审中-公开
标题翻译：作为组胺H3受体调节剂的苯基哌啶和苯基吡啶
公开(公告)号：WO2004037257A1
公开(公告)日：2004-05-06
申请号：PCT/US2003/033809
申请日：2003-10-23
申请人： JANSSEN PHARMACEUTICA, N.V. , APODACA, Richard, L. , DVORAK, Curt, A. , SHAH, Chandravadan, R. , XIAO, Wei,
发明人： APODACA, Richard, L. , DVORAK, Curt, A. , SHAH, Chandravadan, R. , XIAO, Wei,
IPC分类号： A61K31/4545
CPC分类号： C07D401/12 , C07D207/09 , C07D211/26 , C07D211/46 , C07D211/58 , C07D413/10
摘要： Substituted phenylpiperidines and phenylpyrrolidines of formula (I), compositions containing them, and methods of making and using them to treat histamine-mediated conditions.
摘要翻译：取代的苯基哌啶和式（I）的苯基吡咯烷酮，含有它们的组合物，以及制备和使用它们来治疗组胺介导的病症的方法。

28. 发明申请

WO1995010819A1 HANDWRITING AND CHARACTER RECOGNITION SYSTEM 审中-公开
标题翻译：手写和字符识别系统
公开(公告)号：WO1995010819A1
公开(公告)日：1995-04-20
申请号：PCT/US1994011448
申请日：1994-10-07
申请人： DAI, Xiao-Wei
IPC分类号： G06K09/46
CPC分类号： G06K9/00429 , G06K9/00416
摘要： A method and system for oriental language character recognition creates a position code for the starting position of each stroke of the character and a direction code for the direction of each stroke of the character. The direction code is derived from a four-sector direction-code diagram having predetermined angular coverage, and the position code is derived from a position-code diagram for locating the starting point of a stroke with respect to the ending point of a previous stroke. The system uses two-digit binary codes comprising symbols such as "0" and "1" to encode strokes. Character variations having different but acceptable stroke sequences or strokes which may end in different quadrants are accommodated by using a coding symbol such as "x" to represent a "don't care" condition.
摘要翻译：用于东方语言字符识别的方法和系统为字符的每个笔画的起始位置和字符的每个笔划的方向的方向代码创建位置代码。方向代码是从具有预定角度覆盖的四扇区方向代码图导出的，并且位置代码是从位置代码图导出的，用于定位相对于前一笔画的终点的笔画的起始点。该系统使用包括诸如“0”和“1”的符号的两位二进制码来编码笔画。可以通过使用诸如“x”的编码符号来表示“不关心”条件来适应具有可能结束在不同象限中的不同但可接受的笔画序列或笔画的字符变化。

29. 发明申请

WO2012024584A2 OXYSTEROL COMPOUNDS 审中-公开
标题翻译： OXYSTEROL化合物
公开(公告)号：WO2012024584A2
公开(公告)日：2012-02-23
申请号：PCT/US2011/048418
申请日：2011-08-19
申请人： FATE THERAPEUTICS, INC. , XIAO, Wei , EPPERSON, Matt , FAROUZ, Francine , STAPPENBECK, Frank , THORSETT, Eugene
发明人： XIAO, Wei , EPPERSON, Matt , FAROUZ, Francine , STAPPENBECK, Frank , THORSETT, Eugene
IPC分类号： A61K31/58
CPC分类号： A61K45/06 , A61K33/16 , A61K38/1841 , A61K38/29 , A61K38/30 , C07J3/005 , C07J7/001 , C07J9/00 , C07J41/0055 , C07J41/0066 , C07J43/003 , C07J51/00 , A61K2300/00
摘要： Compounds for use in the treatment of bone disorders, obesity, cardiovascular disorders and neurological disorders are disclosed. The compounds have the following structure (I), including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X and R 1 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
摘要翻译：公开了用于治疗骨疾病，肥胖症，心血管疾病和神经疾病的化合物。所述化合物具有以下结构（I），包括其立体异构体，药学上可接受的盐和前药，其中X和R 1如本文所定义。还公开了与这些化合物的制备和使用有关的方法，以及包含这些化合物的药物组合物。

30. 发明申请

WO2010027326A1 PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS 审中-公开
标题翻译：肽类核酸单体和低聚物
公开(公告)号：WO2010027326A1
公开(公告)日：2010-03-11
申请号：PCT/SG2008/000324
申请日：2008-09-03
申请人： NANYANG TECHNOLOGICAL UNIVERSITY , LIU, Chuan Fa , ZENG, Yun , LU, Xiao Wei
发明人： LIU, Chuan Fa , ZENG, Yun , LU, Xiao Wei
IPC分类号： C07D239/557 , C07D473/18 , C07D239/60 , C07D473/34
CPC分类号： C07D239/557 , C07D239/60 , C07D473/18 , C07D473/34 , C07K14/003
摘要： Disclosed is a peptide nucleic acid monomer as well as a corresponding peptide nucleic acid molecule. The monomer comprises a terminal amino group and a terminal group A. The terminal amino group and the terminal group A are connected by an aliphatic moiety. T he main chain of this aliphatic moiety is free of groups that are charged under physiological conditions. The terminal group A is one of -COOH, -COOR 3 , -COX, -COSR 3 , -CN, -CONH 2 , -CONHR 3 , -CONR 3 , R 4 , with R 3 and R4 being H or an aliphatic, alicyclic, aromatic, a rylaliphatic or arylalicyclic group, and X being a halogen atom. The terminal amino group is substituted by an aliphatic group wit h a main chain of at least two carbon atoms and optionally 0 to a bout 2 heteroatoms selected from the group N, O, S, Se and Si. Th e main chain has a polar head group Z.
摘要翻译：公开了肽核酸单体以及相应的肽核酸分子。单体包括末端氨基和末端基团A.末端氨基和末端基团A通过脂肪族部分连接。该脂肪族部分的主链不含在生理条件下带电的基团。末端基团A是-COOH，-COOR 3，-COX，-COSR 3，-CN，-CONH 2，-CONHR 3，-CONR 3，R 4中的一个，其中R 3和R 4是H或脂族，脂环族，芳族，脂族基或芳基脂环基，X为卤素原子。末端氨基被具有至少两个碳原子的主链的任选的脂族基团取代，并且任选地与选自N，O，S，Se和Si的2个杂原子取代。主链有极性头组Z。

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