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21. 发明授权

US08426431B2 Substituted 2-aminoacetamides and the use thereof 有权
标题翻译：取代的2-氨基乙酰胺及其用途
公开(公告)号：US08426431B2
公开(公告)日：2013-04-23
申请号：US12986587
申请日：2011-01-07
申请人： Nancy C. Lan , Yan Wang , Sui Xiong Cai
发明人： Nancy C. Lan , Yan Wang , Sui Xiong Cai
IPC分类号： A61K31/505 , A61K31/47 , A61K31/165
CPC分类号： C07C233/05 , A61K31/165 , C07C237/06 , C07C237/08 , C07C2601/14 , C07D211/46 , C07D213/65 , C07D213/68 , C07D215/20 , C07D239/34 , C07D241/08 , C07D309/12 , C07D317/64
摘要： The invention is directed to substituted 2-aminoacetamides represented by formula (II): and to pharmaceutically acceptable salts and prodrugs thereof, wherein the substituents are defined herein. The invention is also directed to the use of substituted 2-aminoacetamides in methods for the treatment of neuronal damage following global and focal ischemia, and for the treatment, prevention or amelioration of pain, anxiety, or manic depression, as anticonvulsants, as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
摘要翻译：本发明涉及由式（II）表示的取代的2-氨基乙酰胺及其药学上可接受的盐和前药，其中取代基在本文中定义。本发明还涉及取代的2-氨基乙酰胺在治疗全球和局灶性缺血后的神经元损伤的方法中的用途，以及用作治疗，预防或改善作为抗惊厥药物的抗痉挛剂的疼痛，焦虑或躁狂抑郁症，作为局部麻醉剂，作为抗心律失常药物和治疗或预防糖尿病性神经病变。

22. 发明授权

US08426132B2 Quantitative amplification with a labeled probe and 3′ to 5′ exonuclease activity 有权
标题翻译：用标记的探针和3'至5'核酸外切酶活性进行定量扩增
公开(公告)号：US08426132B2
公开(公告)日：2013-04-23
申请号：US12264200
申请日：2008-11-03
申请人： Bin Li , Lei Xi , Yan Wang , Peter B. Vander Horn
发明人： Bin Li , Lei Xi , Yan Wang , Peter B. Vander Horn
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6851 , C12Q2561/101 , C12Q2525/161 , C12Q2521/101 , C12Q2537/143 , C12Q2527/143
摘要： This invention provides methods and kits for performing a quantitative amplification reaction. The method employs a polymerase enzyme and an enzyme having a 3′ to 5′ exonuclease activity that cleaves the 3′ oligonucleotide of the probe.
摘要翻译：本发明提供了进行定量扩增反应的方法和试剂盒。该方法采用聚合酶和具有切割探针的3'寡核苷酸的3'至5'核酸外切酶活性的酶。

23. 发明申请

US20120258460A1 Sso7-Polymerase Conjugates with Decreased Non-Specific Activity 有权
标题翻译：具有降低的非特异性活性的Sso7-聚合酶偶联物
公开(公告)号：US20120258460A1
公开(公告)日：2012-10-11
申请号：US13371126
申请日：2012-02-10
申请人： Man Cheng , Yan Wang , John Sullivan
发明人： Man Cheng , Yan Wang , John Sullivan
IPC分类号： C12Q1/68 , C12N9/96
CPC分类号： C12N9/1241 , C07K2319/80 , C12N9/1252 , C12N9/96 , C12Q1/686
摘要： Improved Sso7-polymerase conjugate proteins are provided
摘要翻译：提供了改进的Sso7聚合酶缀合蛋白

24. 发明申请

US20120198110A1 MAIN BOARD AND METHOD FOR DYNAMICALLY CONFIGURING PCIE PORTS THEREOF 有权
标题翻译：主板和动态配置PCIE端口的方法
公开(公告)号：US20120198110A1
公开(公告)日：2012-08-02
申请号：US13194572
申请日：2011-07-29
申请人： Yan Wang , Yao Guo
发明人： Yan Wang , Yao Guo
IPC分类号： G06F13/00
CPC分类号： G06F13/4081 , G06F2213/0026
摘要： A main board and a method for dynamically configuring PCIE ports thereof. The main board comprises a PCIE slot, a detecting circuit, an ROM, a chipset and a modifying circuit. The chipset comprises a Management Engine controller and several PCIE ports. The chipset has a Management Engine function or a similar function. The detecting circuit detects the PCIE slot to generate a current state parameter. The ROM stores a default configuration data. The modifying circuit coupled between the chipset and the ROM determines whether the default configuration data needs to be modified according to the current state parameter. When the default configuration data needs to be modified, the modifying circuit modifies the default configuration data according to the current state parameter, so that the Management Engine controller initially configures the PCIE ports according to the modified default configuration data. Thus, the dynamical configuration of the chipset PCIE ports is realized.
摘要翻译：一种用于动态配置其PCIE端口的主板和方法。主板包括PCIE插槽，检测电路，ROM，芯片组和修改电路。该芯片组包括一个管理引擎控制器和几个PCIE端口。该芯片组具有管理引擎功能或类似的功能。检测电路检测PCIE插槽以产生当前状态参数。 ROM存储默认配置数据。耦合在芯片组和ROM之间的修改电路确定是否需要根据当前状态参数修改默认配置数据。当需要修改默认配置数据时，修改电路将根据当前状态参数修改默认配置数据，以便管理引擎控制器根据修改的默认配置数据初始配置PCIE端口。因此，实现了芯片组PCIE端口的动态配置。

25. 发明申请

US20120172725A1 COLOR FLOW GAIN ADJUSTMENT METHOD AND DEVICE 有权
标题翻译：颜色流量增益调整方法和设备
公开(公告)号：US20120172725A1
公开(公告)日：2012-07-05
申请号：US13335723
申请日：2011-12-22
申请人： Yan Wang , Xiangzuo Zheng , Yongqiang Dong
发明人： Yan Wang , Xiangzuo Zheng , Yongqiang Dong
IPC分类号： A61B8/14 , G06K9/00
CPC分类号： G06T7/0012 , A61B8/06 , A61B8/14 , A61B8/488 , A61B8/5207
摘要： A color flow gain adjustment method and device, and a color ultrasound imaging system using the device are disclosed.
摘要翻译：公开了一种彩色流量增益调整方法和装置，以及使用该装置的彩色超声成像系统。

26. 发明申请

US20120099473A1 Method and Device for Maintaining Long Term Evolution Base Station 有权
标题翻译：维持长期演进基站的方法和装置
公开(公告)号：US20120099473A1
公开(公告)日：2012-04-26
申请号：US13382521
申请日：2010-07-09
申请人： Weiguo Ma , Bing Liu , Jiye Tang , Yan Wang
发明人： Weiguo Ma , Bing Liu , Jiye Tang , Yan Wang
IPC分类号： H04W24/00 , H04L12/26
CPC分类号： H04W24/04 , H04W76/10 , H04W88/08 , H04W92/12
摘要： A method and a device for maintaining a Long Term Evolution (LTE) base station are provided by the embodiments of the present invention. Depending on the LTE access network system and air interface characteristics, by making a few processing flow changes in such mode or method, a wireless communication link is established between a network maintenance device and a base station to implement the base station maintenance and data communication. Application of the technical solutions provided by the embodiments of the present invention can implement the base station maintenance and data communication by the wireless mode, reduce the cost of the network maintenance and prevent the destruction and influence of human factors on the operation and maintenance of the base station.
摘要翻译：通过本发明的实施例提供了用于维护长期演进（LTE）基站的方法和设备。根据LTE接入网系统和空中接口特性，通过以这种方式或方式进行一些处理流程改变，在网络维护设备和基站之间建立无线通信链路，实现基站维护和数据通信。本发明实施例提供的技术方案的应用可以通过无线方式实现基站维护和数据通信，降低网络维护成本，防止人为因素对操作维护的破坏和影响基站。

27. 发明申请

US20120066368A1 METHOD AND APPARATUS FOR ABSTRACTING LOGICAL TOPOLOGY INFORMATION OF PEER-TO-PEER NETWORK 有权
标题翻译：用于提取对等网络逻辑拓扑信息的方法和装置
公开(公告)号：US20120066368A1
公开(公告)日：2012-03-15
申请号：US13299046
申请日：2011-11-17
申请人： Chunxiu Li , Yan Wang , Guoyi Chen
发明人： Chunxiu Li , Yan Wang , Guoyi Chen
IPC分类号： G06F15/173
CPC分类号： H04L29/06 , H04L29/08072 , H04L41/0213 , H04L45/02 , H04L45/64 , H04L67/104
摘要： The present invention provides a method and an apparatus for abstracting logical topology information of a Peer-to-Peer (P2P) network. The method includes: obtaining a set of Points of Presence (POPs) of peer clients in the P2P network; using a relevant algorithm of a routing protocol to calculate a best path between any two POPs in the set of POPs and a weight value of the best path; and collecting calculation results of the best path and the weight value that are obtained on each POP to obtain a set of abstract logical topology records of the P2P network. The embodiments of the present invention provide a universal and efficient method for abstracting logical topology information, which greatly reduces network topology information that needs to be transmitted, mitigates a risk of exposing lower-layer network topology information, and transmits the network topology information to a P2P application server securely and concisely.
摘要翻译：本发明提供了一种用于抽象对等（P2P）网络的逻辑拓扑信息的方法和装置。该方法包括：获取P2P网络中对等客户端的一组存在点（POP）; 使用路由协议的相关算法来计算POP集合中任何两个POP之间的最佳路径和最佳路径的权重值; 并收集每个POP获得的最佳路径和权重值的计算结果，以获得一组P2P网络的抽象逻辑拓扑记录。本发明的实施例提供了一种通用且有效的抽象逻辑拓扑信息的方法，大大减少了需要传输的网络拓扑信息，减轻了暴露下层网络拓扑信息的风险，并将网络拓扑信息传输到 P2P应用服务器安全简洁。

28. 发明授权

US08101628B2 Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer 失效
标题翻译：咪唑烷酰氨基嘧啶化合物治疗癌症
公开(公告)号：US08101628B2
公开(公告)日：2012-01-24
申请号：US12516514
申请日：2007-12-11
申请人： Harold Burns Brooks , Joyce Z. Crich , James Robert Henry , Hong-Yu Li , Melissa Kate Slater , Yan Wang
发明人： Harold Burns Brooks , Joyce Z. Crich , James Robert Henry , Hong-Yu Li , Melissa Kate Slater , Yan Wang
IPC分类号： C07D401/00
CPC分类号： C07D409/14
摘要： The present invention provides novel imidazolidinonyl aminopyrimidine compounds believed to have clinical use for treatment of cancer through inhibiting Plk1. wherein: R1 hydrogen, hydroxy, halo, methyl, C1-C2 alkoxy, amino, or methylamino; R2 is hydrogen, halo, or cyano; R3 is hydrogen or halo; R4 is hydrogen, halo, or methyl; provided that at least two of R1, R2, R3, and R4 are hydrogen; R5 is hydrogen, halo, or methyl; or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供了被认为具有通过抑制Plk1治疗癌症的临床用途的新型咪唑烷基氨基嘧啶化合物。其中：R 1氢，羟基，卤素，甲基，C 1 -C 2烷氧基，氨基或甲基氨基; R2是氢，卤素或氰基; R3是氢或卤素; R4是氢，卤素或甲基; 条件是R 1，R 2，R 3和R 4中的至少两个为氢; R5是氢，卤素或甲基; 或其药学上可接受的盐。

29. 发明申请

US20120009387A1 FLEXIBLE THERMOPLASTIC FILMS AND ARTICLES 审中-公开
标题翻译：柔性热塑片和文章
公开(公告)号：US20120009387A1
公开(公告)日：2012-01-12
申请号：US13211572
申请日：2011-08-17
申请人： James H. Wang , Peter M. Clark , Yiwu Guan , Yan Wang , Xueen George Hao , Tong-tong Zhang
发明人： James H. Wang , Peter M. Clark , Yiwu Guan , Yan Wang , Xueen George Hao , Tong-tong Zhang
IPC分类号： B32B3/00 , B32B27/32 , C08K13/02 , C08K11/00 , C08K5/1545 , C08K9/04 , B32B5/00 , C08L23/06
CPC分类号： C08J5/18 , C08J2303/00 , C08J2323/04 , C08K5/0008 , C08L3/02 , C08L23/04 , C08L23/08 , C08L23/0815 , C08L2203/162 , C08L2205/025 , C08L2310/00 , Y10T428/24355 , C08L2666/02 , C08L3/04
摘要： A biodegradable, polyolefin-based material composition having incorporated therein thermoplastic starch particles is described. The material includes from about 5% to about 45% of a thermoplastic starch (TPS), from about 55% to about 95% of a polyolefin or mixtures of polyolefins, and from about 0.5% to about 8% of a compatibilizer, which has a non-polar backbone and a polar functional monomer or a block copolymer of both the non-polar block and a polar block. A method of forming a film and packaging assemblies made with the polymeric material are also described.
摘要翻译：描述了其中结合有热塑性淀粉颗粒的可生物降解的聚烯烃基材料组合物。该材料包括约5％至约45％的热塑性淀粉（TPS），约55％至约95％的聚烯烃或聚烯烃混合物，以及约0.5％至约8％的增容剂，其具有非极性主链和极性官能单体或非极性嵌段和极性嵌段的嵌段共聚物。还描述了形成由聚合物材料制成的膜和包装组件的方法。

30. 发明申请

US20120008561A1 METHOD, APPARATUS, AND SYSTEM FOR SENDING A DATA PACKET 有权
标题翻译：用于发送数据包的方法，装置和系统
公开(公告)号：US20120008561A1
公开(公告)日：2012-01-12
申请号：US13234911
申请日：2011-09-16
申请人： Yan Wang , Bo Lin , YuHong Liu
发明人： Yan Wang , Bo Lin , YuHong Liu
IPC分类号： H04W4/00
CPC分类号： H04W36/18 , H04W36/02 , H04W52/54
摘要： The present invention relates to radio communications technologies and discloses a method, an apparatus, and a system for sending a data packet to avoid repeated forwarding of data when a user equipment hands over between an access point and an evolved NodeB. The method includes: receiving, by an evolved NodeB, a data packet sent by a core network and sending the data packet to a current access point; and keeping caching the data packet on the evolved NodeB before determining that a user equipment has correctly received the data packet from the current access point. The present invention is applicable to data transmission in a network.
摘要翻译：本发明涉及无线电通信技术，并且公开了一种方法，装置和系统，用于当用户设备在接入点和演进节点B之间切换时，发送数据分组以避免数据重复转发。该方法包括：由演进的节点B接收由核心网发送的数据分组，并将数据分组发送到当前接入点; 并且在确定用户设备已经从当前接入点正确地接收到数据分组之前，将数据分组保持缓存在演进的节点B上。本发明适用于网络中的数据传输。

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