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31. 发明申请

WO2005010151A2 ANTIBODIES DIRECTED TO THE DELETION MUTANTS OF EPIDERMAL GROWTH FACTOR RECEPTOR AND USES THEREOF 审中-公开
标题翻译：抗体指导表皮生长因子受体的缺失突变及其应用
公开(公告)号：WO2005010151A2
公开(公告)日：2005-02-03
申请号：PCT/US2004020295
申请日：2004-06-25
申请人： ABGENIX INC , WEBER RICHARD , FENG XIAO , FOORD ORIT , GREEN LARRY , GUDAS JEAN , KEYT BRUCE , LIU YING , RATHANASWAMI PALANI , RAYA ROBERT , YANG XIAO DONG , CORVALAN JOSE , FOLTZ IAN , JIA XIAO-CHI , KANG JASPAL , KING CHADWICK T , KLAKAMP SCOTT L , SU QIAOJUAN JANE
发明人： WEBER RICHARD , FENG XIAO , FOORD ORIT , GREEN LARRY , GUDAS JEAN , KEYT BRUCE , LIU YING , RATHANASWAMI PALANI , RAYA ROBERT , YANG XIAO DONG , CORVALAN JOSE , FOLTZ IAN , JIA XIAO-CHI , KANG JASPAL , KING CHADWICK T , KLAKAMP SCOTT L , SU QIAOJUAN JANE
IPC分类号： A61K39/395 , A61K47/48 , C07K16/22 , C07K16/28 , C07K17/00 , C12N20060101 , C12N5/06 , G01N33/53 , C12N
CPC分类号： C07K16/30 , A61K47/6803 , A61K47/6849 , A61K47/6897 , A61K2039/505 , B82Y5/00 , C07K16/2863 , C07K2317/21 , C07K2317/34 , C07K2317/77 , C07K2317/92 , Y10S435/81
摘要： The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.
摘要翻译：本发明涉及新型抗体，特别是针对表皮生长因子受体缺失突变体的抗体，特别是涉及III型缺失突变体EGFRvIII的抗体。本发明还涉及针对表皮生长因子受体缺失突变体特别是EGFRvIII的人单克隆抗体。还提供了此类抗体的诊断和治疗制剂及其免疫缀合物。

32. 发明申请

WO2004102495A3 ELECTRONIC ARTICLE SURVEILLANCE TAG 审中-公开
标题翻译：电子文章监督标签
公开(公告)号：WO2004102495A3
公开(公告)日：2005-01-13
申请号：PCT/US2004014104
申请日：2004-05-06
申请人： FUSS ARTHUR BRADLEY , YANG XIAO HUI
发明人： FUSS ARTHUR BRADLEY , YANG XIAO HUI
IPC分类号： E05B73/00 , G08B13/24 , G08B13/14
CPC分类号： E05B73/0017 , G08B13/2434
摘要： An electronic article surveillance tag features a spindle assembly which anchors and retains a set of ball bearings which are used to clutch and retain the shaft of a tack (24). The spindle (16) features an operational tab which may be contacted by the appropriate probe to turn the spindle (16) about a central axis. The spindle (16) is seated in a retaining means with a graduated lip around the perimeter. The turning of the spindle (16) serves to raise a portion of the spindle (16) from the retaining means, loosening the ball bearing grip on the shaft of the tack. The electronic article surveillance tga may be used with either a smoothed or grooved tack (24) shaft and may be operated by either mechanical probe actuation or by the use of a magnetic detachment means applied to the spindle (16).
摘要翻译：电子物品监视标签具有主轴组件，该主轴组件锚定并保持用于离合并保持钉（24）的轴的一组球轴承。主轴（16）具有可操作的接片，该接片可由适当的探针接触，以使主轴（16）围绕中心轴线旋转。主轴（16）位于具有围绕周边的刻度唇缘的保持装置中。主轴（16）的转动用于将主轴（16）的一部分从保持装置上抬起，松开球杆的轴上的球轴承把手。电子物品监视tga可以与平滑的或带槽的钉（24）轴一起使用，并且可以通过机械探针致动或通过使用施加到主轴（16）的磁性分离装置来操作。

33. 发明申请

WO2004109364A1 FABRICATION OF A HIGH FILL RATIO REFLECTIVE SPATIAL LIGHT MODULATOR WITH HIDDEN HINGE 审中-公开
标题翻译：高密度反射空间光调制器与隐藏式铰链的制造
公开(公告)号：WO2004109364A1
公开(公告)日：2004-12-16
申请号：PCT/US2004/004357
申请日：2004-02-12
申请人： MIRADIA INC. , PAN, Shaoher, X. , YANG, Xiao
发明人： PAN, Shaoher, X. , YANG, Xiao
IPC分类号： G02B26/00
CPC分类号： B81B3/004 , B81B2201/042 , G02B26/0841
摘要： Fabrication of a micro mirror array having a hidden hinge that is useful, for example, in a reflective spatial light modulator. In one embodiment, the micro mirror array is fabricated from a substrate that is a first substrate of a single crystal material. Cavities are formed in a first side of the first substrate. Separately, electrodes and addressing and control circuitry are fabricated on a first side of a second substrate. The first side of the first substrate is bonded to the first side of the second substrate. The sides are aligned so the electrodes on the second substrate are in proper relation with the mirror plates that will be formed on the first substrate and that the electrodes will control. The first substrate is thinned to a predetermined, desired thickness, a hinge is etched, a sacrificial material is deposited, the upper surface of the first substrate is planarized, a reflective surface is deposited to cover the hinge, a mirror is released by etching and the sacrificial layer around the hinge is removed to release the hinge so the hinge can rotate about an axis in line with the hinge.
摘要翻译：具有隐藏铰链的微反射镜阵列的制造，其例如在反射空间光调制器中是有用的。在一个实施例中，微反射镜阵列由作为单晶材料的第一衬底的衬底制成。在第一基板的第一侧形成有凹穴。另外，在第二衬底的第一侧上制造电极和寻址和控制电路。第一衬底的第一侧被结合到第二衬底的第一侧。侧面对齐，使得第二基板上的电极与将在第一基板上形成的反射镜板正确关系，并且电极将被控制。将第一衬底减薄到预定的期望厚度，蚀刻铰链，沉积牺牲材料，第一衬底的上表面被平坦化，沉积反射表面以覆盖铰链，通过蚀刻释放镜子，铰链周围的牺牲层被去除以释放铰链，因此铰链可以围绕与铰链一致的轴线旋转。

34. 发明申请

WO2004012458A2 EFFICIENT VIDEO TRANSMISSION 审中-公开
标题翻译：有效的视频传输
公开(公告)号：WO2004012458A2
公开(公告)日：2004-02-05
申请号：PCT/SG2002/000168
申请日：2002-07-26
申请人： NANYANG TECHNOLOGICAL UNIVERSITY , YANG, Xiao, Kang , YU, Rong, Shan , ZHU, Ce , LIM, Keng, Pang , LI, Zheng, Guo , PAN, Feng , FENG, Ge, Nan , WU, Da, Jun , WU, Si
发明人： YANG, Xiao, Kang , YU, Rong, Shan , ZHU, Ce , LIM, Keng, Pang , LI, Zheng, Guo , PAN, Feng , FENG, Ge, Nan , WU, Da, Jun , WU, Si
IPC分类号： H04N7/26
CPC分类号： H04N19/51 , H04N19/557
摘要： A method and system for reducing the complexity of block motion estimation is described. According to the invention, the block distortion measure is determined by calculating a partial error result using a proportion of pixels in the block, comparing the partial error result with a threshold value and rejecting blocks where the partial error result is greater than the threshold value, and calculating a full error result for non-rejected blocks only. The threshold value is a function of the current minimum partial error result, and is preferably the current minimum partial error result multiplied by a threshold constant λ. Another aspect of the invention provides a video transport scheme which exploits the different importance of both GOP and re-synchronisation levels. According to this aspect, an unequal loss protection (ULP) philosophy is utilized. That is, the bit stream data is partitioned into several parts according to different importance, and the parts are unequally protected against packet loss using forward error correction codes.
摘要翻译：描述了一种降低块运动估计复杂度的方法和系统。根据本发明，通过使用块中的像素的比例来计算部分误差结果来确定块失真度量，将部分错误结果与阈值进行比较，并且拒绝部分错误结果大于阈值的块，并仅计算未拒绝块的完整错误结果。阈值是当前最小部分误差结果的函数，并且优选地是当前最小部分误差结果乘以阈值常数λ1。本发明的另一方面提供一种视频传输方案，其利用GOP和重新同步级别的不同重要性。根据这一方面，利用了不平等的损失保护（ULP）理念。也就是说，根据不同的重要性将比特流数据划分成若干部分，并且使用前向纠错码对这些部分进行不均匀的保护以防止丢包。

35. 发明申请

WO9945031A9 CD147 BINDING MOLECULES AS THERAPEUTICS 审中-公开
标题翻译： CD147结合分子作为治疗药物
公开(公告)号：WO9945031A9
公开(公告)日：1999-11-11
申请号：PCT/US9904583
申请日：1999-03-03
申请人： ABGENIX INC , DAVIS C GEOFFREY , BLACHER RUSSELL W , CORVALAN JOSE R , CULWELL ALAN R , GREEN LARRY L , HALES JOANNA , HAVRILLA NANCY , IVANOV VLADIMIR E , LIPANI JOHN A , LIU QIANG , WEBER RICHARD F , YANG XIAO DONG
发明人： DAVIS C GEOFFREY , BLACHER RUSSELL W , CORVALAN JOSE R , CULWELL ALAN R , GREEN LARRY L , HALES JOANNA , HAVRILLA NANCY , IVANOV VLADIMIR E , LIPANI JOHN A , LIU QIANG , WEBER RICHARD F , YANG XIAO-DONG
IPC分类号： G01N33/53 , A61K39/395 , A61P19/02 , A61P29/00 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06 , A61P37/08 , C07K14/705 , C07K16/28 , C12N15/09 , C12P21/08 , G01N33/577
CPC分类号： C07K16/2803 , A61K2039/505 , C07K14/70596 , C07K16/2896 , C07K2317/21 , C07K2317/34 , C07K2317/732 , C07K2317/734 , C07K2317/92 , C07K2319/00 , C07K2319/30
摘要： In accordance with the present invention, we have discovered that the molecule CD147 as expressed on certain cells, such as T-cells, B-cells, and/or monocytes, can be utilized for the treatment of a variety of diseases. In particular, we have demonstrated that antibodies that bind to CD147 and that result in the killing of such cells, for example, through the binding of complement, is efficacious in the treatment of diseases. Diseases in which such treatment appears efficacious include, without limitation: graft versus host disease (GVHD), organ transplant rejection diseases (including, without limitation, renal transplant, ocular transplant, and others), cancers (including, without limitation, cancers of the blood (i.e., leukemias and lymphomas), pancreatic, and others), autoimmune diseases, inflammatory diseases, and others.
摘要翻译：根据本发明，我们发现在某些细胞如T细胞，B细胞和/或单核细胞上表达的分子CD147可用于治疗各种疾病。特别是，我们已经证明结合CD147并导致这些细胞例如通过结合补体而杀死这些细胞的抗体在治疗疾病中是有效的。这种治疗看起来有效的疾病包括但不限于：移植物抗宿主病（GVHD），器官移植排斥疾病（包括但不限于肾移植，眼移植等），癌症（包括但不限于癌症血液（即白血病和淋巴瘤），胰腺癌等），自身免疫性疾病，炎症性疾病等。

36. 发明申请

WO2021196157A1 GEAR TRAINS 审中-公开
公开(公告)号：WO2021196157A1
公开(公告)日：2021-10-07
申请号：PCT/CN2020/083185
申请日：2020-04-03
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY,L.P. , XING, Zhi-Wen , ZHU, Xu-ri , ZHAO, Zhi-Yuan , ZHU, Shuang-Kun , JING, Yue , YANG, Xiao-Li
发明人： XING, Zhi-Wen , ZHU, Xu-ri , ZHAO, Zhi-Yuan , ZHU, Shuang-Kun , JING, Yue , YANG, Xiao-Li
IPC分类号： B41J23/02
摘要： A gear train that includes: a drive gear, a slave gear (102-1, 102-2) to directly interact with the drive gear, a shaft rotation gear (110-1, 110-2) to directly interact with the slave gear (102-1, 102-2), wherein a direction of the slave gear (102-1, 102-2) alters a position of the shaft rotation gear (110-1, 110-2) between a first position and a second position, a torque gear (126-1, 126-2) to interact with the shaft rotation gear (110-1, 110-2) when the shaft rotation gear (110-1, 110-2) is in the first position, and a locking device (120-1, 120-2) to interact with the shaft rotation gear (110-1, 110-2) when the shaft rotation gear (110-1, 110-2) is in the second position.

37. 发明申请

WO2021173691A1 EAS DEVICE WITH ELASTIC BAND 审中-公开
公开(公告)号：WO2021173691A1
公开(公告)日：2021-09-02
申请号：PCT/US2021/019440
申请日：2021-02-24
申请人： YANG, Xiao, Hui
发明人： YANG, Xiao, Hui
IPC分类号： E05B45/00 , E05B73/00 , G08B13/14 , G08B13/24
摘要： An electronic article surveillance (EAS) device for monitoring items comprises an electronics housing and an elastic band. The band is attached to the housing and is used to install the EAS device onto an item. A tension monitoring apparatus monitors the band and generates a signal based on the band's state of tension. Electronics within the housing receive this signal and use it to determine the status of the EAS device, i.e. installed, armed, tampered with, etc. Loss of tension may indicate a cut band or removed EAS device. Other sensors may also generate inputs for the electronics to evaluate. These include an installation sensor to monitor contact between the housing and an item and an arming switch to arm the EAS device before installation. The EAS device may have wireless communication capabilities, and external devices may arm and disarm the device with wireless communication.

38. 发明申请

WO2014138718A2 ELECTRONIC ARTICLE SURVEILLANCE RELAY DEVICE 审中-公开
标题翻译：电子文件监控继电器
公开(公告)号：WO2014138718A2
公开(公告)日：2014-09-12
申请号：PCT/US2014022198
申请日：2014-03-08
申请人： YANG XIAO HUI
发明人： YANG XIAO HUI
IPC分类号： G06K7/10
CPC分类号： G06K7/10188 , E05B73/0029 , E05B73/0058 , G08B13/1463 , G08B13/2417 , G08B13/2434 , G08B13/2448
摘要： An electronic article surveillance device attaches to an object having an electronic article surveillance RFID label in it. The EAS device interrogates the label for information and associates itself with the label. The device retransmits the information from the label to the broader system and over a longer range than the label can by itself. The device has a motion detector and periodically interrogates the label to insure the presence of the label, especially when motion is detected. The unexpected absence of the label is considered an alarm condition and the device will alarm in those circumstances. External devices arm and disarm the device and detach the device as well.
摘要翻译：电子物品监视装置附着在其中具有电子物品监视RFID标签的物体上。 EAS设备询问标签以获取信息，并将其与标签相关联。设备将信息从标签重新传输到更广泛的系统，并且在标签可以自身的范围之外。该装置具有运动检测器，并周期性地询问标签以确保标签的存在，特别是当检测到运动时。标签的意外缺少被认为是报警状态，并且在这种情况下设备将报警。外部设备也会对设备进行手动和撤防操作，同时拆卸设备。

39. 发明申请

WO2013041397A1 ARTIFICIAL LEATHER WITH IMPROVED FLEXING ENDURANCE PROPERTIES 审中-公开
标题翻译：具有改进的弯曲性能的人造革
公开(公告)号：WO2013041397A1
公开(公告)日：2013-03-28
申请号：PCT/EP2012/067635
申请日：2012-09-10
申请人： BASF SE , REDL, Franz Xaver , EMGE, Andreas , FENG, YueXia , CHEN, Cheun-Gwo , YANG, Xiao-Kun , REESE, Oliver
发明人： REDL, Franz Xaver , EMGE, Andreas , FENG, YueXia , CHEN, Cheun-Gwo , YANG, Xiao-Kun , REESE, Oliver
IPC分类号： D06N3/00 , D06N3/14
CPC分类号： B29C39/146 , A43B23/0235 , B32B37/24 , B32B37/26 , B32B2037/243 , B32B2037/268 , D06N3/0097 , D06N3/14 , D06N3/145 , D06N3/183 , D06N2211/106 , D06N2211/28 , Y10T428/24967
摘要： The present invention relates to a process for production of artificial leather comprising top coat, polyurethane layer and optional substrate layer, said process comprising i)providing a release layer,ii)applying one or more than one layer of a top coat to the release layer to an overall top coat layer thickness in the range from 1 to 500 µm,iii)applying first polyurethane system components comprising an isocyanate component (A) and a polyol component (B) to the top coat to form a first polyurethane layer, wherein the isocyanate index of the first polyurethane system components is in the range from 101 to 140, iv) optionally applying further polyurethane system components to the first polyurethane layer to form further polyurethane layers,v)optionally applying a substrate layer to the polyurethane system components, vi)curing the polyurethane system components to form a polyurethane layer, and vii)separating the release layer from the top coat, wherein the overall thickness of the first and optionally further polyurethane layers is in the range from 0.01 to 20 mm and the polyurethane system components are solvent-free. The present invention further relates to an artificial leather obtainable by such a process and to the use of the artificial leather as upper materials for footwear.
摘要翻译：本发明涉及一种生产人造革的方法，其包括面漆，聚氨酯层和任选的基底层，所述方法包括i）提供剥离层，ii）将一层或多层顶涂层施加到剥离层至1至500μm范围内的整体顶涂层厚度，iii）将包含异氰酸酯组分（A）和多元醇组分（B）的第一聚氨酯体系组分施加到顶涂层以形成第一聚氨酯层，其中第一聚氨酯体系组分的异氰酸酯指数在101至140的范围内，iv）任选地将另外的聚氨酯体系组分施加到第一聚氨酯层以形成其它聚氨酯层，v）任选地将基材层施加到聚氨酯体系组分，vi ）固化聚氨酯体系组分以形成聚氨酯层，以及vii）将脱模层与顶涂层分离，其中整个薄膜的厚度第一和任选地，其它聚氨酯层的范围为0.01至20mm，并且聚氨酯体系组分是无溶剂的。本发明还涉及通过这种方法获得的人造革，以及人造革作为鞋类的上部材料的用途。

40. 发明申请

WO2012015493A1 MULTI-PATH RADIO SYSTEM 审中-公开
标题翻译：多路无线电系统
公开(公告)号：WO2012015493A1
公开(公告)日：2012-02-02
申请号：PCT/US2011/030580
申请日：2011-03-30
申请人： AIRGAIN, INC. , YANG, Xiao, Ping , VISURI, Pertti
发明人： YANG, Xiao, Ping , VISURI, Pertti
IPC分类号： H04B7/04 , H04W88/08
CPC分类号： H04B7/0413 , H04B7/0837 , H04B7/0868 , H04L27/06
摘要： Systems and methods for a MIMO radio with antenna signal combiners are presented. In one embodiment, a (MIMO) radio system for use in a multi-path environment is described. The system includes a plurality of antenna subsystems, each subsystem comprising two or more antennas and a combiner configured to combine signals received via the two or more antennas in a ratio. The system further includes a radio for each of the plurality of antenna subsystems configured to demodulate the combined signal and a MIMO processor configured to produce a single data stream from the demodulated signals.
摘要翻译：提出了一种具有天线信号组合器的MIMO无线电的系统和方法。在一个实施例中，描述了在多路径环境中使用的（MIMO）无线电系统。该系统包括多个天线子系统，每个子系统包括两个或多个天线，以及组合器，其被配置为组合经由两个或多个天线以一定比例接收的信号。该系统还包括用于解调组合信号的多个天线子系统中的每一个的无线电装置，以及被配置为从解调信号产生单个数据流的MIMO处理器。

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