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    • 55. 发明申请
    • AIR ADMITTANCE VALVE
    • 空气阀门
    • WO2015166402A1
    • 2015-11-05
    • PCT/IB2015/053061
    • 2015-04-27
    • IPS CORPORATION
    • COLE, Steven R.
    • E03C1/122
    • E03C1/1225F16K17/12Y10T137/7897
    • An air admittance valve which when subjected to a negative pressure condition vents a pipe system to an ambient environment. Generally, the air admittance valve includes a housing (102), a cartridge (120), and a sealing member (110). The housing includes one or more vents (104, 106) disposed in its wall and may be engaged with the pipe system at one end. The cartridge may have one or more inlets (122, 124) defining one or more inlet openings, where the one or more inlets is connected to a central chamber (170) that has an opening with a sealing structure. The sealing member (110) interacts with the sealing structure of the cartridge to allow one-way airflow from the central chamber to the pipe system. The cartridge and sealing member may be inserted into the housing such that the one or more inlet openings substantially align with the one or more vents in the housing.
    • 空气导纳阀,当经受负压条件时,将管道系统排放到周围环境。 通常,空气导纳阀包括壳体(102),盒(120)和密封构件(110)。 壳体包括设置在其壁中的一个或多个通气口(104,106),并且可以在一端与管道系统接合。 盒可以具有限定一个或多个入口开口的一个或多个入口(122,124),其中一个或多个入口连接到具有带有密封结构的开口的中心室(170)。 密封构件(110)与筒的密封结构相互作用以允许从中心室到管道系统的单向气流。 盒和密封构件可以插入到壳体中,使得一个或多个入口开口基本上与壳体中的一个或多个通气口对准。
    • 57. 发明申请
    • METHODS AND COMPOSITIONS FOR PREDICTING MINIMAL RESIDUAL DISEASE IN ACUTE LYMPHOBLASTIC LEUKEMIA
    • 急性淋巴细胞白血病预防最小残疾病的方法与组合
    • WO2015112442A1
    • 2015-07-30
    • PCT/US2015/011736
    • 2015-01-16
    • ST. JUDE CHILDREN'S RESEARCH HOSPITAL
    • LEUNG, WingBARTHEL, Erin
    • C12Q1/68
    • C12Q1/6886C12Q1/6804C12Q2600/118C12Q2600/156C12Q2600/158
    • Methods and compositions are provided for predicting minimal residual disease (MRD) before induction chemotherapy in a subject having acute lymphoblastic leukemia (ALL). Compositions comprising a plurality of probes for determining the expression levels of a panel of markers in a biological sample, wherein a first probe specifically binds to PI-9, a second probe specifically binds to FasL, a third probe specifically binds to Granzyme B, and a fourth probe specifically binds to NKp46; at least one probe capable of detecting a KIR2DL5A genotype. Various methods of employing such compositions to predict MRD before induction chemotherapy in a subject having ALL are also provided, as are methods for generating a prognostic test to predict a MRD positive probability before induction chemotherapy in a subject having ALL.
    • 提供了方法和组合物,用于预测急性淋巴细胞性白血病(ALL)患者的诱导化疗前的最小残留病(MRD)。 包含用于确定生物样品中一组标志物的表达水平的多个探针的组合物,其中第一探针特异性结合PI-9,第二探针特异性结合FasL,第三探针特异性结合颗粒酶B,以及 第四个探针特异性结合NKp46; 至少一种能够检测KIR2DL5A基因型的探针。 还提供了使用这样的组合物在具有ALL的受试者中诱导化疗之前预测MRD的各种方法,以及用于产生用于预测具有ALL的受试者中的诱导化学疗法之前的MRD阳性概率的预后测试的方法。
    • 59. 发明申请
    • SURGICAL DRAPE FOR COLLECTING DISCHARGED FLUID
    • 用于收集排出的流体的外科皮肤
    • WO2014197306A1
    • 2014-12-11
    • PCT/US2014/040193
    • 2014-05-30
    • THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY D/B/A CAROLINAS HEALTHCARE SYSTEM
    • MARSHBURN, Paul B.
    • A61B19/08A61B17/42A61B19/10A61B19/00
    • A61B46/30A61B2046/205A61B2046/236A61B2090/063
    • A surgical drape (100) is described that is aimed at providing a way to direct a maximum amount of fluid (e.g., distention fluid) discharged from the patient's uterine cavity to a collection point, such as a fluid management system, during a hysteroscopic procedure. The surgical drape may include a cover portion (105) and a collection portion (110) that is attached to the cover portion (105). The cover portion (105) may define an opening (115) that provides a surgeon with surgical access to the patient for performing a medical procedure. The collection portion (110) may include a main panel (120) that can be attached to the patient's back distally of the gluteal cleft (e.g., via an adhesive strip). The main panel (110) may include a pocket (170), via which the surgeon may insert his hands to position the main panel (110) under the patient without disturbing the sterile field.
    • 描述了一种手术罩(100),其旨在提供一种在宫腔镜手术期间将从患者子宫腔排出的最大量的流体(例如膨胀液)引导到收集点(例如流体管理系统)的方法 。 手术罩可以包括盖部分(105)和附接到盖部分(105)的收集部分(110)。 盖部分(105)可以限定一个开口(115),该开口(115)为外科医生提供对病人的手术进入以执行医疗程序。 收集部分(110)可以包括主面板(120),该主面板可以连接到患者的背部的臀裂口(例如经由粘合剂条)。 主面板(110)可以包括口袋(170),外科医生可以通过该口袋插入他的手以将主面板(110)定位在患者身下,而不干扰无菌区域。
    • 60. 发明申请
    • APPARATUS AND METHOD FOR REPRESENTING AND MANIPULATING METADATA
    • 装置和方法代表和处理元数据
    • WO2014195851A1
    • 2014-12-11
    • PCT/IB2014/061894
    • 2014-06-02
    • NOKIA CORPORATIONNOKIA USA INC.
    • LEHTINIEMI, Arto JuhaniERONEN, Antti JohannesARRASVUORI, Juha HenrikHOLM, Jukka Antero
    • G06F3/048G06F17/30
    • G06F17/30265G06F17/30038
    • Mechanisms are described for providing visual representations of metadata so as to allow for an easier, more intuitive, and more entertaining way for a user to manage metadata by allowing a user to execute operations relating to the metadata through interactions with the visual representations of that metadata. A user can further define visual objects and use such objects for searching media content items, such as by using a visual representation of metadata as a filter and displaying graphical depictions of associations between the visual representations of metadata and the associated media content item. Moreover, operations executed on the visual representations, such as copying, pasting, and modifying the visual representations, are translated to actions on the metadata itself and can be applied across different devices, as well as different media content items and groups of media content items.
    • 描述用于提供元数据的视觉表示的机制,以便允许用户通过与该元数据的视觉表示的交互来执行与元数据相关的操作来管理元数据的更简单,更直观和更有趣的方式 。 用户可以进一步定义可视对象并使用这样的对象来搜索媒体内容项,例如通过使用元数据的可视表示作为过滤器,并且显示元数据的可视表示与相关联的媒体内容项之间的关联的图形描绘。 此外,对诸如复制,粘贴和修改视觉表示的视觉表示执行的操作被转换为元数据本身上的动作,并且可以应用于不同的设备以及不同的媒体内容项目和媒体内容项目组 。