专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

51. 发明申请

US20120276017A1 Methods and Compositions for Treatment of Attention Deficit Disorder 有权
标题翻译：治疗注意力缺陷障碍的方法和组成
公开(公告)号：US20120276017A1
公开(公告)日：2012-11-01
申请号：US13429292
申请日：2012-03-23
申请人： David Lickrish , Feng Zhang
发明人： David Lickrish , Feng Zhang
IPC分类号： A61K9/54 , A61K31/137 , A61K31/4458 , A61K9/58 , A61P25/00 , A61P25/24 , A61P25/18 , A61K9/62 , A61K9/14 , A61K31/165
CPC分类号： A61K9/5073 , A61K9/5026 , A61K9/5047 , A61K31/137 , A61K31/4458
摘要： Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms that deliver a therapeutic amount of active drug in a delayed and controlled release formulation. The dosage form can be administered at night and drug release is delayed for from 3 to 8 hours, followed by an ascending release rate.
摘要翻译：用于治疗注意力缺陷障碍（ADD）或注意缺陷多动障碍（ADHD）的治疗组合物和方法包括在延迟和控制释放制剂中递送治疗量的活性药物的剂型。剂型可以在晚上施用，药物释放延迟3至8小时，然后延长释放速率。

52. 发明申请

US20120219620A1 SCF Extract Containing Cardiac Glycoside 有权
标题翻译：含有心脏糖苷的SCF提取物
公开(公告)号：US20120219620A1
公开(公告)日：2012-08-30
申请号：US13417686
申请日：2012-03-12
申请人： O.Cradell Addington , Feng Zhang , John J. Koleng
发明人： O.Cradell Addington , Feng Zhang , John J. Koleng
IPC分类号： A61K36/24 , A61P31/12 , A61P35/00 , A61K9/48 , A61K31/704
CPC分类号： A61K36/24
摘要： A supercritical fluid (SCF) extract of a cardiac glycoside-containing plant mass is provided. The extract can be included in a pharmaceutical composition containing an extract-solubilizing amount of solubilizer. Oleandrin is included within the extract when a cardiac glycoside-containing plant, such as Nerium oleander, is extracted by SCF extraction. The extract can also contain one or more other SCF extractable pharmacologically active agents. The composition can be used to treat a wide range of disorders that are therapeutically responsive to a cardiac glycoside.
摘要翻译：提供了含有强心苷的植物体的超临界流体（SCF）提取物。提取物可以包含在含有提取物增溶量的增溶剂的药物组合物中。当通过SCF提取提取含有含有强心苷的植物，例如夹心夹心素时，包含在提取物中。提取物还可以含有一种或多种其它SCF可提取的药理学活性剂。该组合物可用于治疗对心脏糖苷治疗响应的各种各样的疾病。

53. 发明授权

US08237055B2 Circuit board 失效
标题翻译：电路板
公开(公告)号：US08237055B2
公开(公告)日：2012-08-07
申请号：US12564734
申请日：2009-09-22
申请人： Wang-Jia Chen , Wei Zhou , Yu-Hsu Lin , Feng Zhang
发明人： Wang-Jia Chen , Wei Zhou , Yu-Hsu Lin , Feng Zhang
IPC分类号： H05K1/00
CPC分类号： H05K1/025 , H05K1/0245 , H05K2201/09236 , H05K2201/09318 , H05K2201/09345 , H05K2201/09727
摘要： A circuit board includes an insulation layer, a signal layer disposed on one side of the insulation layer, and a ground plane and a power plane disposed on the insulation layer at a side opposite to the signal layer. The insulation layer forms a separating area arranged between the ground plane and the power plane. At least two signal traces parallel to each other are arranged on the signal layer at one side corresponding to one of the ground plane and the power plane. A width of the signal trace close to the separating area is wider than that of the signal trace away from the separating area.
摘要翻译：电路板包括绝缘层，设置在绝缘层的一侧的信号层，以及设置在与信号层相对的一侧的绝缘层上的接地面和电源面。绝缘层形成布置在接地平面和电源平面之间的分离区域。彼此平行的至少两条信号迹线在对应于接地平面和电源平面之一的一侧上布置在信号层上。靠近分离区域的信号迹线的宽度比远离分离区域的信号迹线宽。

54. 发明申请

US20120178131A1 TAL EFFECTOR-MEDIATED DNA MODIFICATION 有权
公开(公告)号：US20120178131A1
公开(公告)日：2012-07-12
申请号：US13427040
申请日：2012-03-22
申请人： Daniel F. Voytas , Adam J. Bogdanove , Feng Zhang
发明人： Daniel F. Voytas , Adam J. Bogdanove , Feng Zhang
IPC分类号： C12N15/63 , C12P19/34 , C07H1/08 , C12N15/55
CPC分类号： C12N9/22 , C12N15/01 , C12N15/102 , C12N15/1082 , C12N15/62 , C12N15/63 , C12Y301/21004
摘要： Materials and methods related to gene targeting (e.g., gene targeting with transcription activator-like effector nucleases; “TALENS”) are provided.
摘要翻译：提供了与基因靶向相关的材料和方法（例如，用转录激活子样效应核酸酶进行基因靶向;“TALENS”）。

55. 发明申请

US20110301529A1 SYSTEMS, METHODS AND COMPOSITIONS FOR OPTICAL STIMULATION OF TARGET CELLS 有权
标题翻译：用于目标细胞光刺激的系统，方法和组合物
公开(公告)号：US20110301529A1
公开(公告)日：2011-12-08
申请号：US13208419
申请日：2011-08-12
申请人： Feng Zhang , Karl Deisseroth , Viviana Gradinaru
发明人： Feng Zhang , Karl Deisseroth , Viviana Gradinaru
IPC分类号： A61M37/00 , C12N13/00
CPC分类号： A61N5/062 , A01K67/0333 , A01K2217/052 , A01K2227/703 , A01K2267/0356 , A61K38/00 , A61K48/005 , A61K48/0058 , A61K48/0083 , A61N5/0613 , A61N5/0622 , C07K14/00 , C07K14/195 , C07K14/215 , C12N13/00 , C12N15/86 , C12N2710/10343 , C12N2710/16643 , C12N2740/16043 , C12N2740/16071 , C12N2750/14143 , C12N2830/002
摘要： Stimulation of target cells using light, e.g., in vivo or in vitro, is implemented using a variety of methods and devices. One example involves a vector for delivering a light-activated NpHR-based molecule comprising a nucleic acid sequence that codes for light-activated NpHR-based molecule and a promoter. Either a high expression of the molecule manifests a toxicity level that is less than about 75%, or the light-activated NpHR-based proteins are expressed using at least two NpHR-based molecular variants. Each of the variants characterized in being useful for expressing a light-activated NpHR-based molecule that responds to light by producing an inhibitory current to dissuade depolarization of the neuron. Other aspects and embodiments are directed to systems, methods, kits, compositions of matter and molecules for ion pumps or for controlling inhibitory currents in a cell (e.g., in in vivo and in vitro environments).
摘要翻译：使用光，例如体内或体外，使用各种方法和装置来实施靶细胞的刺激。一个实例涉及用于递送光激活的基于NpHR的分子的载体，其包含编码基于光激活的基于NpHR的分子和启动子的核酸序列。分子的高表达表现出小于约75％的毒性水平，或者使用至少两种基于NpHR的分子变体表达光激活的NpHR基蛋白。每个变体的特征在于可用于表达基于光激活的基于NpHR的分子，其通过产生抑制电流来抑制神经元的去极化来响应光。其他方面和实施方案涉及用于离子泵的物质和分子的组合物，或用于控制细胞中的抑制性电流（例如在体内和体外环境中）的系统，方法，试剂盒，组合物。

56. 发明申请

US20110230502A1 MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH 有权
标题翻译：化学感受器的调节和与之相关的配体
公开(公告)号：US20110230502A1
公开(公告)日：2011-09-22
申请号：US13051586
申请日：2011-03-18
申请人： Catherine TACHDJIAN , Xiao-Qing Tang , Sara Werner , Marketa Rinnova , Qing Chen , Guy Servant , Xiaodong Li , Feng Zhang , Haitian Liu , Albert Zlotnik , Mark Zoller , Boris Klebansky , Richard Fine , Xinshan Kang
发明人： Catherine TACHDJIAN , Xiao-Qing Tang , Sara Werner , Marketa Rinnova , Qing Chen , Guy Servant , Xiaodong Li , Feng Zhang , Haitian Liu , Albert Zlotnik , Mark Zoller , Boris Klebansky , Richard Fine , Xinshan Kang
IPC分类号： A61K31/519 , A61K31/522 , A61K31/437 , A61K31/4355 , A61K31/4365 , A61P27/00
CPC分类号： C07D513/04 , A23L2/39 , A23L2/60 , A23L27/30 , A23L27/31 , A23L27/33 , A23L27/34 , A23L27/88 , C07D215/42 , C07D215/54 , C07D215/56 , C07D239/70 , C07D239/84 , C07D239/94 , C07D239/95 , C07D285/16 , C07D417/04 , C07D417/12 , C07D471/04 , C07D487/04 , C07D491/04 , C07D491/056 , C07D493/04 , C07D495/04 , C07D495/14 , C07D513/20 , G01N33/566
摘要： The present invention provides screening methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors as well as modifiers capable of modulating chemosensory receptors and their ligands.
摘要翻译：本发明提供了用于鉴定化学感受器及其配体的调节剂的筛选方法，例如通过确定测试实体是否适合与化学感应受体的金星蝇捕获结构域内的一个或多个相互作用位点相互作用，以及能调节化学感受器及其配体。

57. 发明授权

US07692155B2 Three-dimensional, position-sensitive radiation detection 有权
标题翻译：三维，位置敏感的辐射检测
公开(公告)号：US07692155B2
公开(公告)日：2010-04-06
申请号：US12190385
申请日：2008-08-12
申请人： Zhong He , Feng Zhang
发明人： Zhong He , Feng Zhang
IPC分类号： G01T1/24
CPC分类号： G01T1/247 , G01T7/005
摘要： Disclosed herein is a method of determining a characteristic of radiation detected by a radiation detector via a multiple-pixel event having a plurality of radiation interactions. The method includes determining a cathode-to-anode signal ratio for a selected interaction of the plurality of radiation interactions based on electron drift time data for the selected interaction, and determining the radiation characteristic for the multiple-pixel event based on both the cathode-to-anode signal ratio and the electron drift time data. In some embodiments, the method further includes determining a correction factor for the radiation characteristic based on an interaction depth of the plurality of radiation interactions, a lateral distance between the selected interaction and a further interaction of the plurality of radiation interactions, and the lateral positioning of the plurality of radiation interactions.
摘要翻译：本文公开了一种通过具有多个辐射相互作用的多像素事件来确定由辐射检测器检测的辐射的特性的方法。该方法包括基于所选择的相互作用的电子漂移时间数据确定多个辐射相互作用的选定相互作用的阴极至阳极信号比，以及基于阴极 - 阴极两者确定多像素事件的辐射特性，阳极信号比和电子漂移时间数据。在一些实施例中，该方法还包括基于多个辐射相互作用的相互作用深度，所选择的相互作用与多个辐射相互作用的进一步相互作用之间的横向距离以及横向定位的多个辐射相互作用。

58. 发明授权

US07592924B2 Intelligent life testing methods and apparatus for leakage current protection 有权
标题翻译：智能寿命测试方法和设备，用于漏电流保护
公开(公告)号：US07592924B2
公开(公告)日：2009-09-22
申请号：US11588048
申请日：2006-10-25
申请人： Feng Zhang , Hongliang Chen , Fu Wang , Wusheng Chen , Yulin Zhang , Huaiyin Song
发明人： Feng Zhang , Hongliang Chen , Fu Wang , Wusheng Chen , Yulin Zhang , Huaiyin Song
IPC分类号： G08B21/00
CPC分类号： H02H3/335 , H02H3/021
摘要： An apparatus for testing the life of a leakage current protection device having a leakage current detection circuit and a trip mechanism having a switch device. In one embodiment, the apparatus a ground fault simulation unit, a fault detector of the leakage current detection circuit and the trip mechanism, and a life testing detection control unit having an MCU for controlling operation of the fault detector. In operation, a first signal (pulse signal) is sent to the gate of the switching device to generate a first voltage at the cathode of the switching device, a second signal is sent to the ground fault simulation unit to generate a simulated ground fault for the leakage current detection circuit to generate a second voltage at the gate of the switching device, and the first and second voltages are measured to determine whether a fault exists in the leakage current detection circuit and the trip mechanism.
摘要翻译：一种用于测试具有泄漏电流检测电路的漏电流保护装置的寿命的装置和具有开关装置的跳闸机构。在一个实施例中，该装置是接地故障模拟单元，泄漏电流检测电路的故障检测器和跳闸机构，以及具有用于控制故障检测器的操作的MCU的寿命测试检测控制单元。在操作中，第一信号（脉冲信号）被发送到开关装置的栅极，以在开关装置的阴极处产生第一电压，第二信号被发送到接地故障模拟单元以产生模拟接地故障测量在开关装置的栅极处产生第二电压的漏电流检测电路以及第一和第二电压，以确定泄漏电流检测电路和跳闸机构中是否存在故障。

59. 发明授权

US07590116B2 Method for forwarding multicast message in network communication 有权
标题翻译：在网络通信中转发多播消息的方法
公开(公告)号：US07590116B2
公开(公告)日：2009-09-15
申请号：US10629376
申请日：2003-07-28
申请人： Qiang He , Feng Zhang
发明人： Qiang He , Feng Zhang
IPC分类号： H04L12/28
CPC分类号： H04L45/00 , H04L12/1836 , H04L45/16
摘要： The invention relates to a method of forwarding multicast message in network communication. In the method: first, establish forwarding match condition at the ingress interface of the network device required to forward multicast message, the forwarding match condition specifies forwarding rule for the multicast message; then, compare the multicast message to be forwarded to network device through the interface with the forwarding match condition, and forward the multicast message according to the comparing result. The invention can configure the sending mode of messages according to requirement and can effectively avoid risks in security that may be caused by the broadcast mode for the multicast messages in the link layer as well as efficiency loss caused by receiving a great deal of invalid multicast messages, and the configuration is simple, and more convenient use and management is realized. In the present invention, forwarding multicast message according to an established multicast message forwarding rule greatly reduces the number of various multicast protocol messages generated in the multicast network and saves bandwidth resource of network.
摘要翻译：本发明涉及一种在网络通信中转发多播消息的方法。在该方法中，首先在转发组播报文所需的网络设备的入口接口上建立转发匹配条件，转发匹配条件指定组播报文的转发规则; 然后通过具有转发匹配条件的接口比较要转发到网络设备的组播报文，并根据比较结果转发组播报文。本发明可以根据需要配置消息的发送方式，有效避免链路层组播消息广播模式引起的安全隐患风险以及接收到大量无效组播报文的效率损失，配置简单，使用和管理更方便实现。在本发明中，根据建立的组播消息转发规则转发组播消息大大减少了组播网络中生成的各种组播协议报文的数量，节省了网络的带宽资源。

60. 发明申请

US20090093403A1 SYSTEMS, METHODS AND COMPOSITIONS FOR OPTICAL STIMULATION OF TARGET CELLS 审中-公开
标题翻译：用于目标细胞光刺激的系统，方法和组合物
公开(公告)号：US20090093403A1
公开(公告)日：2009-04-09
申请号：US12041628
申请日：2008-03-03
申请人： Feng Zhang , Karl Deisseroth , Viviana Gradinaru
发明人： Feng Zhang , Karl Deisseroth , Viviana Gradinaru
IPC分类号： A61K38/17 , C07H21/04 , C07K14/435 , A61P25/00 , C12N15/63
CPC分类号： A61N5/062 , A01K67/0333 , A01K2217/052 , A01K2227/703 , A01K2267/0356 , A61K38/00 , A61K48/005 , A61K48/0058 , A61K48/0083 , A61N5/0613 , A61N5/0622 , C07K14/00 , C07K14/195 , C07K14/215 , C12N13/00 , C12N15/86 , C12N2710/10343 , C12N2710/16643 , C12N2740/16043 , C12N2740/16071 , C12N2750/14143 , C12N2830/002
摘要： Stimulation of target cells using light, e.g., in vivo or in vitro, is implemented using a variety of methods and devices. One example involves a vector for delivering a light-activated NpHR-based molecule comprising a nucleic acid sequence that codes for light-activated NpHR-based molecule and a promoter. Either a high expression of the molecule manifests a toxicity level that is less than about 75%, or the light-activated NpHR-based proteins are expressed using at least two NpHR-based molecular variants. Each of the variants characterized in being useful for expressing a light-activated NpHR-based molecule that responds to light by producing an inhibitory current to dissuade depolarization of the neuron. Other aspects and embodiments are directed to systems, methods, kits, compositions of matter and molecules for ion pumps or for controlling inhibitory currents in a cell (e.g., in in vivo and in vitro environments).
摘要翻译：使用光，例如体内或体外，使用各种方法和装置来实施靶细胞的刺激。一个实例涉及用于递送光激活的基于NpHR的分子的载体，其包含编码基于光激活的基于NpHR的分子和启动子的核酸序列。分子的高表达表现出小于约75％的毒性水平，或者使用至少两种基于NpHR的分子变体表达光激活的NpHR基蛋白。每个变体的特征在于可用于表达基于光激活的基于NpHR的分子，其通过产生抑制电流来抑制神经元的去极化来响应光。其他方面和实施方案涉及用于离子泵的物质和分子的组合物，或用于控制细胞中的抑制性电流（例如在体内和体外环境中）的系统，方法，试剂盒，组合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式