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61. 发明申请

WO1995029352A1 GASKETS 审中-公开
公开(公告)号：WO1995029352A1
公开(公告)日：1995-11-02
申请号：PCT/GB1995000701
申请日：1995-03-29
申请人： T & N TECHNOLOGY LIMITED , PERCIVAL, Paul, Reuben , HARLAND, Christopher, Robin , EASTHAM, David, Raymond , JOHAL, Charan, Preet, Singh
发明人： T & N TECHNOLOGY LIMITED
IPC分类号： F16J15/08
CPC分类号： F16J15/0818 , F16J15/0825 , F16J2015/0837 , F16J2015/085 , F16J2015/0862
摘要： A gasket (10; 50) comprises at least one metal sheet (12; 52) which extends generally parallel to sealing surfaces (11a, 13a) of the gasket. The metal sheet has deposited metal (20; 54) thereon forming a functional projection, e.g. to limit compression of the gasket. The metal is deposited on the surface (12a, 12b; 52a) of the sheet by electroplating.
摘要翻译：垫圈（10; 50）包括至少一个大致平行于垫圈的密封表面（11a，13a）延伸的金属片（12; 52）。金属片在其上沉积金属（20; 54），形成功能突起，例如以限制垫圈的压缩。金属通过电镀沉积在片材的表面（12a，12b; 52a）上。

62. 发明申请

WO1994002152A2 PHOSPHONO DERIVATIVES AS ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS 审中-公开
标题翻译：磷酸衍生物作为抗炎和抗感染药物
公开(公告)号：WO1994002152A2
公开(公告)日：1994-02-03
申请号：PCT/US1993004891
申请日：1993-05-27
申请人： THE UPJOHN COMPANY , WHITE, David, Raymond , FRITZEN, Edward, Lawrence, Jr.
发明人： THE UPJOHN COMPANY
IPC分类号： A61K31/66
CPC分类号： C07F9/655345 , A61K31/66 , A61K31/67 , A61K31/675 , C07F9/2458 , C07F9/247 , C07F9/2475 , C07F9/3821 , C07F9/3882 , C07F9/4012 , C07F9/4015 , C07F9/4056 , C07F9/4081 , C07F9/5728 , C07F9/58 , C07F9/62 , C07F9/6512
摘要： Various novel phosphono derivatives (XII) of amino acid esters such as the "nonphenyl-type" N-phosphono compounds of formula (IX): R6-CH(NR7-PO(OR4)(OR5))COOR3, the "phenyl-type" N-phosphono compounds of formula (X): R8-CH(NR9-PO(OR4)(OR5))COOR3, and the "phenylethylene-type" N-phosphono compounds of formula (XI): R10-CH(NR11-PO(OR4)(OR5))COOR3 are disclosed as being useful as antiinflammatory and antiarthritic agents. Further disclosed is a method of treating inflammatory and arthritic disease with known N-phosphono derivatives of amino acid esters, the "benzyl-type" N-phosphono compounds of formula (III): R1-CH(NR2-PO(OR4)(OR5))COOR3. Additionally disclosed are N,N'-diphosphonodiamine esters of formula (XV) and phosphonophosphinate esters of formula (XVIII): R14-X-(CW)m1-CR15R16-CH2-CM(P(O)(OR4)(OR5))(P(O)(OR4)(R19)) also useful for treating inflammatory and arthritic diseases.
摘要翻译：式（Ⅸ）的“非苯基型”N-膦酰基化合物：R6-CH（NR7-PO（OR4）（OR5））COOR3等氨基酸酯的新型膦酰基衍生物（Ⅻ），“苯基型式（X）的N-膦酰基化合物：R8-CH（NR9-PO（OR4）（OR5））COOR3和式（XI）的“苯基乙烯型”N-膦酰基化合物：R10-CH（NR11- PO（OR4）（OR5））COOR3被公开用作抗炎和抗关节炎药物。还公开了一种使用已知的氨基酸N-膦酰基衍生物（式（III）的“苄基型”N-膦酰基化合物：R1-CH（NR2-PO（OR4）（OR5））来治疗炎性和关节炎疾病的方法））COOR3。另外公开了式（XV）的N，N'-二膦酰二胺酯和式（XVIII）的膦酸膦酯：R14-X-（CW）m1-CR15R16-CH2-CM（P（O）（OR4）（OR5））（P（O）（OR4）（R19））也可用于治疗炎性和关节炎疾病。

63. 发明申请

WO2012007747A2 DAMPING DEVICE 审中-公开
标题翻译：阻尼装置
公开(公告)号：WO2012007747A2
公开(公告)日：2012-01-19
申请号：PCT/GB2011/051304
申请日：2011-07-12
申请人： DAVE HICKS GOLF LIMITED , HICKS, David Raymond
发明人： HICKS, David Raymond
IPC分类号： A63B53/00
CPC分类号： A63B53/10 , A63B53/00 , A63B53/007 , A63B53/12 , A63B57/60 , A63B60/36 , A63B60/54 , F16F7/00 , Y10T29/49826
摘要： A golf club (2) comprising a shaft (20), a head and a damping device (1, 100). The damping device (1, 100) includes an anchor element (3, 103) and a damping element (4, 104) interconnected by a rigid rod (5, 105). The anchor element (3, 103) is anchored within the lower section of the shaft (20) that has a substantially constant diameter such that the damping element (4, 104) is in contact with an internal surface of the shaft (20) to dampen vibrations therein.
摘要翻译：一种包括轴（20），头部和阻尼装置（1,100）的高尔夫球杆（2）。阻尼装置（1,100）包括通过刚性杆（5,105）互连的锚固元件（3,103）和阻尼元件（4,104）。锚固元件（3,103）锚固在轴（20）的下部内，其具有基本上恒定的直径，使得阻尼元件（4,104）与轴（20）的内表面接触到抑制其中的振动。

64. 发明申请

WO2011146172A1 PROGRESSIVE CHARTING 审中-公开
标题翻译：积极进取
公开(公告)号：WO2011146172A1
公开(公告)日：2011-11-24
申请号：PCT/US2011/031937
申请日：2011-04-11
申请人： SOLARWINDS WORLDWIDE LLC , MALTBY, David, Raymond , DOLISY, Joel
发明人： MALTBY, David, Raymond , DOLISY, Joel
IPC分类号： G06F7/00
CPC分类号： H04L43/067 , H04L41/22 , H04L43/026 , H04L43/045 , H04L43/062
摘要： Embodiments of the invention include an apparatus, method, and computer program for progressive charting of network traffic flow data. The method includes, in one example, receiving, at a network traffic analyzer, a query of network traffic flow data over a certain time period. The method further includes modifying the query to produce sub-queries each based on different segments of time within the certain time period, executing at least one of the sub-queries, and incrementally outputting results of each of said executed sub-queries as each of the sub-queries are completed.
摘要翻译：本发明的实施例包括用于逐行图表网络业务流数据的装置，方法和计算机程序。在一个示例中，该方法包括在网络流量分析器处在一定时间段内接收网络业务流数据的查询。所述方法还包括：修改所述查询以产生子查询，每个子查询基于所述特定时间段内的不同时间段，执行所述子查询中的至少一个，并将每个所述执行的子查询的结果递增地输出为子查询完成。

65. 发明申请

WO2008133754A3 SERRATED MEMS RESONATORS 审中-公开
标题翻译： SERRATED MEMS谐振器
公开(公告)号：WO2008133754A3
公开(公告)日：2008-12-31
申请号：PCT/US2007088196
申请日：2007-12-19
申请人： SITIME INC , HAGELIN PAUL MERRITT , PEDERSEN DAVID RAYMOND
发明人： HAGELIN PAUL MERRITT , PEDERSEN DAVID RAYMOND
IPC分类号： H02N2/00 , H01L41/00
CPC分类号： H02N1/008 , H03H9/02275 , H03H9/2468 , H03H2009/02496
摘要： One embodiment of the present invention sets forth a serrated tooth actuator for driving MEMS resonator structures. The actuator includes a fixed drive electrode having a serrated tooth surface opposing a MEMS resonator arm also having a serrated tooth surface, where the MEMS resonator arm is configured to rotate towards the drive electrode when an AC signal is applied to the drive electrode. Such a configuration permits higher amplitude signals to be applied to the drive electrode without the performance of the actuator being compromised by nonlinear effects. In addition, the serrated tooth configuration enables a sufficiently high actuating force to be maintained even though the distance traversed by the MEMS resonator arm during operation is quite small. Further, the serrated configuration allows a MEMS resonator system to withstand larger fluctuations in voltage and larger substrate stresses without experiencing a substantial shift in resonant frequency.
摘要翻译：本发明的一个实施例提出了用于驱动MEMS谐振器结构的锯齿状致动器。致动器包括固定的驱动电极，其具有与具有锯齿状齿表面的MEMS谐振器臂相对的锯齿状齿表面，其中，当将CCP信号施加到驱动电极时，MEMS谐振臂被配置为朝向驱动电极旋转。这种配置允许更高幅度的信号被施加到驱动电极，而不会使致动器的性能受到非线性效应的影响。此外，即使在操作期间由MEMS谐振器臂穿过的距离相当小，锯齿形齿构造也能够保持足够高的致动力。此外，锯齿形配置允许MEMS谐振器系统承受较大的电压波动和较大的衬底应力，而不会发生谐振频率的实质性偏移。

66. 发明申请

WO2008005455A3 PEPTIDE ANTIBODY DEPLETION AND ITS APPLICATION TO MASS SPECTROMETRY SAMPLE PREPARATION 审中-公开
公开(公告)号：WO2008005455A3
公开(公告)日：2008-01-10
申请号：PCT/US2007/015390
申请日：2007-07-03
申请人： THE JOHNS HOPKINS UNIVERSITY , VAN EYK, Jennifer, E. , GRAHAM, David, Raymond , GUNDRY, Rebekah, Lynn
发明人： VAN EYK, Jennifer, E. , GRAHAM, David, Raymond , GUNDRY, Rebekah, Lynn
IPC分类号： G01N33/68 , G01N33/543 , C07K16/00
摘要： The present invention relates, e.g., to a method for pre-processing a sample for mass spectral analysis, comprising cleaving proteins in the sample to peptides and immunodepleting highly abundant and/or well-ionizing and/or proteotypic peptides from the sample. Also described are methods for identifying well-ionizing peptides for use in this and other methods; analytic (diagnostic) methods using antibodies against highly ionizable peptides from a protein target of interest; and compositions, kits and devices comprising antibodies of the invention.

67. 发明申请

WO2007126799A2 COMPOSITIONS AND METHODS OF USE FOR ANTIBODIES OF C-MET 审中-公开
标题翻译：用于C-MET抗体的组合物和方法
公开(公告)号：WO2007126799A2
公开(公告)日：2007-11-08
申请号：PCT/US2007/007543
申请日：2007-03-29
申请人： NOVARTIS AG , NOVARTIS PHARMA GmbH , STOVER, David Raymond , PRASSLER, Josef , BERGER, Catrin , BROCKS, Bodo
发明人： STOVER, David Raymond , PRASSLER, Josef , BERGER, Catrin , BROCKS, Bodo
IPC分类号： C07K16/28
CPC分类号： C07K16/2863 , C07K2317/21 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92 , Y10S435/81
摘要： Antibodies and fragments that bind to the protein target c Met, particularly to epitopes located in the c Met extracellular domain, are provided, as are methods of use of the antibodies and kits, for treating an unwanted cell, in particular, a cell associated with a c Met-related condition such as a cancer, a metastasis, or an inflammatory condition.
摘要翻译：提供了结合蛋白质靶标c Met的抗体和片段，特别是位于c Met细胞外结构域中的表位，以及使用抗体和试剂盒的方法，用于治疗不想要的细胞，特别是与 ac Met相关病症如癌症，转移或炎性病症。

68. 发明申请

US20220099699A1 ACOUSTIC INTENSITY SENSOR USING A MEMS TRIAXIAL ACCELEROMETER AND MEMS MICROPHONES 有权
公开(公告)号：US20220099699A1
公开(公告)日：2022-03-31
申请号：US17332390
申请日：2021-05-27
申请人： James W. Waite , David Raymond Dall'Osto , Peter Hans Dahl
发明人： James W. Waite , David Raymond Dall'Osto , Peter Hans Dahl
IPC分类号： G01P15/18 , H04R29/00 , G10K11/00
摘要： An airborne acoustic vector sensor for simultaneously measuring triaxial particle acceleration in three dimensions and pressure includes a triaxial MEMS accelerometer sensitive to an Earth gravitational field. The airborne acoustic vector sensor includes one or multiple MEMS microphones sensitive to sound pressure and overlapping the accelerometer in frequency. The airborne acoustic vector sensor includes a solid body having a density approximating a density of air. The accelerometer is mounted in or upon the solid body. The airborne acoustic vector sensor includes a suspension system supporting the accelerometer and solid body within a framework.

69. 发明申请

US20200327502A1 Project Management Method 审中-公开
公开(公告)号：US20200327502A1
公开(公告)日：2020-10-15
申请号：US16796916
申请日：2020-02-20
申请人： David & Raymond Patent Firm
发明人： Raymond Y. CHAN , Rihui CHEN , Xueguang DONG , Tiaowan LIU , Wei DU , Xiaoxiao DUAN
IPC分类号： G06Q10/10 , G06Q10/06 , G06Q50/18
摘要： The present invention provides a project management method, which comprises the steps of: (A) analyzing a resource demand of the project according to a project view of at least a project; (B) analyzing an available time of the resources according to a resource view of at least a resource; (C) calling the resources to the project according to the resource demand and the available time of the resources.

70. 发明申请

US20200327479A1 Bidirectional Selecting System and Bidirectional Selecting Method between Service Objects and Service Providers 审中-公开
公开(公告)号：US20200327479A1
公开(公告)日：2020-10-15
申请号：US16796919
申请日：2020-02-20
申请人： David & Raymond Patent Firm
发明人： Raymond Y. CHAN , Rihui CHEN , Xueguang DONG , Tiaowan LIU , Wei DU , Xiaoxiao DUAN
IPC分类号： G06Q10/06 , G06Q30/06
摘要： A bidirectional selecting method, between service objects and service providers, includes the steps of: after acquiring an expression data about a user, acquiring at least intentional object in a corresponding object database based on the expression data and a background information of the user to obtain a processing result; and outputting the processing result, wherein when the user is a service object, the object database is a service provider database, wherein when the user is a service provider, the object database is a service object database.

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