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61. 发明申请

US20080210856A1 Fingerprinting of Complex Hydrocarbon Containing Mixtures 失效
标题翻译：含复合烃混合物的指纹图谱
公开(公告)号：US20080210856A1
公开(公告)日：2008-09-04
申请号：US10587805
申请日：2005-02-07
申请人： Ingvar Eide , Kolbjorn Zahlsen
发明人： Ingvar Eide , Kolbjorn Zahlsen
IPC分类号： B01D59/44
CPC分类号： H01J49/0431 , G01N30/724 , G01N30/7266 , G01N33/2823
摘要： The invention provides a method of analysing a complex hydrocarbon-containing mixture, the method comprising the steps of: obtaining a liquid sample of the complex hydrocarbon-containing mixture; injecting the sample into a liquid carrier flowing to a mass spectrometer, wherein the mass spectrometer is set so as to ionise molecules in the sample without causing fragmentation thereof; recording a mass spectrum for ions obtained from the sample; and using the mass spectrum to obtain fingerprint of the mixture. {dot over (a)}In one embodiment, two or more mass spectra are recorded and are combined to obtain a fingerprint of the mixture.
摘要翻译：本发明提供一种分析复合含烃混合物的方法，所述方法包括以下步骤：获得所述复合烃混合物的液体样品; 将样品注入流向质谱仪的液体载体中，其中设置质谱仪以使样品中的分子离子化而不引起其分裂; 记录从样品获得的离子的质谱; 并使用质谱获得混合物的指纹。 {dot over（a）在一个实施方案中，记录两个或更多个质谱，并将其组合以获得该混合物的指纹。

62. 发明授权

US4383171A Particle analyzing method and apparatus 失效
标题翻译：粒子分析方法和装置
公开(公告)号：US4383171A
公开(公告)日：1983-05-10
申请号：US207135
申请日：1980-11-17
申请人： Mahadeva P. Sinha , Charles E. Giffin , David D. Norris , Sheldon K. Friedlander
发明人： Mahadeva P. Sinha , Charles E. Giffin , David D. Norris , Sheldon K. Friedlander
IPC分类号： G01N1/22 , G01N15/14 , G01N30/72 , H01J49/16 , B01D59/44
CPC分类号： H01J49/164 , G01N30/72 , H01J49/0445 , G01N1/2208 , G01N2001/2223 , G01N2030/7226 , G01N30/724 , G01N30/7293
摘要： A system is provided for analyzing the particles in aerosols, as in making air pollution studies, which enables the making of rapid chemical analyses of particles. The system includes an apparatus for producing a controlled stream of individual particles to be analyzed from an environment, and an apparatus for vaporizing and ionizing the particles while they move in free flight, for analysis by a mass spectrometer. The apparatus for producing a stream of particles includes a capillary tube through which the air with suspended particles moves, a skimmer device having a small opening spaced from an end of the capillary tube to receive particles passing through the tube, and a vacuum pump for pumping air out of the space between the tube and skimmer. The vacuum pump serves to remove much of the gas from around the particles, while also creating an inflow of air and particles through the capillary tube. The particles passing through the skimmer opening can be simultaneously vaporized and ionized while in free flight, by a laser beam of sufficient intensity that is directed across the path of the free flying particles.
摘要翻译：提供了一种用于分析气溶胶中的颗粒的系统，如进行空气污染研究，其能够进行颗粒的快速化学分析。该系统包括用于从环境产生待分析的单个颗粒的受控流的装置，以及用于在颗粒自由飞行中移动并使其离子化并使其离子化的装置，用于通过质谱仪进行分析。用于生产颗粒物流的装置包括：毛细管，悬浮颗粒的空气通过该毛细管移动，具有与毛细管的端部间隔开的小开口的分离器装置，以接收穿过该管的颗粒;以及抽真空泵空气从管和撇渣器之间的空间排出。真空泵用于从颗粒周围除去大部分气体，同时还产生空气和颗粒通过毛细管的流入。通过分离器开口的颗粒可以在自由飞行中同时被蒸发并离子化，并通过被引导穿过自由飞行颗粒的路径的足够强度的激光束进行离子化。

63. 发明公开

KR1020170130454A 기체성 샘플의 개선된 이온화 방법 审中-实审
标题翻译：气体样品改进的电离方法
公开(公告)号：KR1020170130454A
公开(公告)日：2017-11-28
申请号：KR1020177028157
申请日：2016-03-07
申请人： 마이크로매스 유케이 리미티드
发明人： 존스,엠리스 , 카란시,타마스 , 프린글,스티븐데레크 , 발로그,줄리아 , 시몬,다니엘 , 고도르하지,라조스 , 스잘레이,다니엘 , 타카츠,졸탄
IPC分类号： G01N27/62 , H01J49/00 , H01J49/04 , H01J49/06 , H01J49/16 , G01N33/92 , A61B10/00 , A61B10/02
CPC分类号： H01J49/049 , A61B1/00013 , A61B1/041 , A61B1/31 , A61B5/0066 , A61B5/0075 , A61B5/015 , A61B5/0507 , A61B5/055 , A61B5/14542 , A61B6/032 , A61B6/037 , A61B8/13 , A61B10/00 , A61B10/0041 , A61B10/0233 , A61B10/0283 , A61B17/00 , A61B17/320068 , A61B18/00 , A61B18/042 , A61B18/14 , A61B18/1445 , A61B18/1815 , A61B18/20 , A61B90/13 , A61B2010/0083 , A61B2017/320069 , A61B2018/00577 , A61B2218/008 , A61F13/38 , C12Q1/025 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/2202 , G01N3/00 , G01N9/00 , G01N27/622 , G01N27/624 , G01N30/724 , G01N33/487 , G01N33/48735 , G01N33/6848 , G01N33/6851 , G01N33/92 , G01N2001/2223 , G01N2333/195 , G01N2405/00 , G01N2405/04 , G01N2405/08 , G01N2570/00 , G01N2800/26 , G06F19/18 , G06F19/324 , G06F19/3481 , G16H50/20 , H01J49/0004 , H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/0404 , H01J49/0422 , H01J49/0445 , H01J49/0459 , H01J49/0463 , H01J49/0468 , H01J49/061 , H01J49/068 , H01J49/10 , H01J49/14 , H01J49/16 , H01J49/164 , H01J49/24 , H01J49/26
摘要： 하기단계를포함하는질량분광분석또는이온이동도분광분석방법이개시된다: 분석물(201)의제공단계; 상기분석물(201)이상기매트릭스(204)에서용해하도록상기분석물(201)에매트릭스(204) 화합물의공급단계; 용해된분석물(205)의제1 액적의형성단계; 및충돌표면(209)과상기제1 액적(205)의충돌단계. 매트릭스의이용은분석물이온신호를개선한다.
摘要翻译：一种质谱或离子迁移谱分析方法，包括以下步骤：提供分析物（201）; 将基质（204）化合物馈送到分析物（201）以溶解在分析物（201）移相器基质（204）中; 形成溶解分析物205的液滴的步骤; 碰撞碰撞表面（209）和叠加的液滴（205）的步骤。使用矩阵可以改善分析物离子信号。

64. 发明公开

KR1020140041642A 질량 분광법에 기반한 페니실륨 종들의 화학적 분류용 키트 有权
标题翻译：基于质谱法的基于化学分类的化学品
公开(公告)号：KR1020140041642A
公开(公告)日：2014-04-04
申请号：KR1020140023660
申请日：2014-02-27
申请人： 건국대학교 산학협력단
发明人： 이충환 , 김향연
IPC分类号： G01N30/72 , C12Q1/04
CPC分类号： G01N30/7206 , C12Q1/04 , G01N30/724 , G01N2030/8813 , G01N2030/884 , G01N2333/385
摘要： The present invention relates to a kit for the mass spectrometry based chemotaxonomy of penicillium species. The kit is a kit for identifying Penicillium oxalicum which contains compounds including vermiculidiol, meleagrin, oxaline, glandicolin, glandicolin B, and secalonic acid D.
摘要翻译：本发明涉及一种用于基于质谱法的青霉菌化学化学方法的试剂盒。该试剂盒是一种用于鉴定草酸青霉菌的试剂盒，其中含有ermiculidiol，meleagrin，oxaline，glandicolin，glandicolin B和secalonic acid D等化合物。

65. 发明授权

US11710627B2 Cell population analysis 有权
公开(公告)号：US11710627B2
公开(公告)日：2023-07-25
申请号：US17558925
申请日：2021-12-22
申请人： Micromass UK Limited
发明人： Emrys Jones , Steven Derek Pringle , Keith Richardson , James Ian Langridge , Zoltan Takats
IPC分类号： G01N30/72 , H01J49/04 , A61B10/02 , A61B18/00 , A61B18/14 , A61B18/20 , G01N3/00 , G01N9/00 , G01N33/68 , H01J49/00 , H01J49/06 , H01J49/16 , G16B20/50 , G01N27/623 , A61B90/13 , A61B1/04 , A61B1/273 , A61B5/00 , A61B5/01 , A61B5/0507 , A61B5/055 , A61B6/03 , A61B8/13 , A61B10/00 , A61B17/00 , A61B18/04 , A61B18/18 , A61F13/38 , C12Q1/02 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/22 , G01N27/624 , G01N33/487 , G01N33/92 , H01J49/02 , H01J49/10 , H01J49/14 , H01J49/24 , H01J49/26 , G16B20/00 , A61B17/32 , G16H10/40 , G16H15/00 , G16H50/20 , A61B1/00 , A61B1/31 , A61B5/145
CPC分类号： H01J49/049 , A61B1/041 , A61B1/2736 , A61B5/0066 , A61B5/0075 , A61B5/015 , A61B5/055 , A61B5/0507 , A61B6/032 , A61B6/037 , A61B8/13 , A61B10/00 , A61B10/0041 , A61B10/0233 , A61B10/0283 , A61B17/00 , A61B18/00 , A61B18/04 , A61B18/042 , A61B18/14 , A61B18/1445 , A61B18/1815 , A61B18/20 , A61B90/13 , A61F13/38 , C12Q1/025 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/2202 , G01N3/00 , G01N9/00 , G01N27/623 , G01N27/624 , G01N30/724 , G01N33/487 , G01N33/6848 , G01N33/6851 , G01N33/92 , G16B20/50 , H01J49/0004 , H01J49/0027 , H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/044 , H01J49/0404 , H01J49/0409 , H01J49/0422 , H01J49/0445 , H01J49/0459 , H01J49/0463 , H01J49/0468 , H01J49/061 , H01J49/068 , H01J49/10 , H01J49/14 , H01J49/16 , H01J49/164 , H01J49/24 , H01J49/26 , A61B1/00013 , A61B1/31 , A61B5/14542 , A61B17/320068 , A61B2010/0083 , A61B2017/320069 , A61B2018/00577 , A61B2018/00589 , A61B2018/00994 , A61B2218/002 , A61B2218/008 , G01N33/48735 , G01N2001/2223 , G01N2333/195 , G01N2405/00 , G01N2405/04 , G01N2405/08 , G01N2570/00 , G01N2800/26 , G16B20/00 , G16H10/40 , G16H15/00 , G16H50/20
摘要： A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

66. 发明授权

US10840076B2 Ionisation of gaseous samples 有权
公开(公告)号：US10840076B2
公开(公告)日：2020-11-17
申请号：US15555758
申请日：2016-03-07
申请人： Micromass UK Limited
发明人： Emrys Jones , Tamas Karancsi , Steven Derek Pringle , Julia Balog , Daniel Simon , Lajos Godorhazy , Daniel Szalay , Zoltan Takats
IPC分类号： H01J49/00 , H01J49/04 , A61B10/02 , A61B17/32 , A61B18/00 , A61B18/14 , A61B18/20 , G01N3/00 , G01N9/00 , G01N33/68 , H01J49/06 , H01J49/16 , A61B90/13 , A61B1/04 , A61B1/273 , A61B5/00 , A61B5/01 , A61B5/05 , A61B5/055 , A61B6/03 , A61B8/13 , A61B10/00 , A61B17/00 , A61B18/04 , A61B18/18 , A61F13/38 , C12Q1/02 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/22 , G01N27/62 , G01N30/72 , G01N33/487 , G01N33/92 , H01J49/02 , H01J49/10 , H01J49/14 , H01J49/24 , H01J49/26 , G16B20/00 , G16H10/40 , G16H15/00 , G16H50/20 , A61B1/00 , A61B1/31 , A61B5/145 , G06F19/00
CPC分类号： H01J49/049 , A61B1/041 , A61B1/2736 , A61B5/0066 , A61B5/0075 , A61B5/015 , A61B5/055 , A61B5/0507 , A61B6/032 , A61B6/037 , A61B8/13 , A61B10/00 , A61B10/0041 , A61B10/0233 , A61B10/0283 , A61B17/00 , A61B17/320068 , A61B18/00 , A61B18/04 , A61B18/042 , A61B18/14 , A61B18/1445 , A61B18/1815 , A61B18/20 , A61B90/13 , A61F13/38 , C12Q1/025 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/2202 , G01N3/00 , G01N9/00 , G01N27/622 , G01N27/624 , G01N30/724 , G01N33/487 , G01N33/6848 , G01N33/6851 , G01N33/92 , H01J49/0004 , H01J49/0027 , H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/044 , H01J49/0404 , H01J49/0409 , H01J49/0422 , H01J49/0445 , H01J49/0459 , H01J49/0463 , H01J49/0468 , H01J49/061 , H01J49/068 , H01J49/10 , H01J49/14 , H01J49/16 , H01J49/164 , H01J49/24 , H01J49/26 , A61B1/00013 , A61B1/31 , A61B5/14542 , A61B2010/0083 , A61B2017/320069 , A61B2018/00577 , A61B2018/00589 , A61B2018/00994 , A61B2218/002 , A61B2218/008 , G01N33/48735 , G01N2001/2223 , G01N2333/195 , G01N2405/00 , G01N2405/04 , G01N2405/08 , G01N2570/00 , G01N2800/26 , G06F19/324 , G06F19/3481 , G16B20/00 , G16H10/40 , G16H15/00 , G16H50/20
摘要： A method of mass spectrometry or ion mobility spectrometry is disclosed comprising: providing an analyte; supplying a matrix compound to said analyte such that said analyte dissolves in said matrix; forming first droplets of the dissolved analyte; and colliding said first droplets with a collision surface. The use of matrix improves the analyte ion signal.

67. 发明申请

US20180059126A1 Cell Population Analysis 审中-公开
公开(公告)号：US20180059126A1
公开(公告)日：2018-03-01
申请号：US15555694
申请日：2016-03-07
申请人： Micromass UK Limited
发明人： Emrys JONES , Steven Derek PRINGLE , Keith RICHARDSON , James Ian LANGRIDGE , Zoltan TAKATS
IPC分类号： G01N33/92 , A61B10/00 , G01N9/00 , A61B18/14 , H01J49/00 , H01J49/04 , A61B17/00 , H01J49/16 , H01J49/06
CPC分类号： H01J49/049 , A61B1/00013 , A61B1/041 , A61B1/2736 , A61B1/31 , A61B5/0066 , A61B5/0075 , A61B5/015 , A61B5/0507 , A61B5/055 , A61B5/14542 , A61B6/032 , A61B6/037 , A61B8/13 , A61B10/00 , A61B10/0041 , A61B10/0233 , A61B10/0283 , A61B17/00 , A61B17/320068 , A61B18/00 , A61B18/04 , A61B18/042 , A61B18/14 , A61B18/1445 , A61B18/1815 , A61B18/20 , A61B90/13 , A61B2010/0083 , A61B2017/320069 , A61B2018/00577 , A61B2018/00589 , A61B2018/00994 , A61B2218/002 , A61B2218/008 , A61F13/38 , C12Q1/025 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/2202 , G01N3/00 , G01N9/00 , G01N27/622 , G01N27/624 , G01N30/724 , G01N33/487 , G01N33/48735 , G01N33/6848 , G01N33/6851 , G01N33/92 , G01N2001/2223 , G01N2333/195 , G01N2405/00 , G01N2405/04 , G01N2405/08 , G01N2570/00 , G01N2800/26 , G06F19/324 , G06F19/3481 , G16B20/00 , G16H10/40 , G16H15/00 , G16H50/20 , H01J49/0004 , H01J49/0027 , H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/0404 , H01J49/0409 , H01J49/0422 , H01J49/044 , H01J49/0445 , H01J49/0459 , H01J49/0463 , H01J49/0468 , H01J49/061 , H01J49/068 , H01J49/10 , H01J49/14 , H01J49/16 , H01J49/164 , H01J49/24 , H01J49/26
摘要： A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

68. 发明申请

US20180057852A1 Spectrometric Analysis of Microbes 审中-公开
公开(公告)号：US20180057852A1
公开(公告)日：2018-03-01
申请号：US15556022
申请日：2016-03-07
申请人： Micromass UK Limited
发明人： Zoltan TAKATS , Frances BOLT , Tamas KARANCSI , Emrys JONES , Keith RICHARDSON , Lajos GODORHAZY , Daniel SZALAY , Julia BALOG , Steven Derek PRINGLE , Daniel SIMON
IPC分类号： C12Q1/04 , G01N33/92 , G01N1/22 , C12Q1/18 , C12Q1/02 , C12Q1/24 , G01N27/62 , H01J49/00 , H01J49/16
CPC分类号： H01J49/049 , A61B1/00013 , A61B1/041 , A61B1/2736 , A61B1/31 , A61B5/0066 , A61B5/0075 , A61B5/015 , A61B5/0507 , A61B5/055 , A61B5/14542 , A61B6/032 , A61B6/037 , A61B8/13 , A61B10/00 , A61B10/0041 , A61B10/0233 , A61B10/0283 , A61B17/00 , A61B17/320068 , A61B18/00 , A61B18/04 , A61B18/042 , A61B18/14 , A61B18/1445 , A61B18/1815 , A61B18/20 , A61B90/13 , A61B2010/0083 , A61B2017/320069 , A61B2018/00577 , A61B2018/00589 , A61B2018/00994 , A61B2218/002 , A61B2218/008 , A61F13/38 , C12Q1/025 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/2202 , G01N3/00 , G01N9/00 , G01N27/622 , G01N27/624 , G01N30/724 , G01N33/487 , G01N33/48735 , G01N33/6848 , G01N33/6851 , G01N33/92 , G01N2001/2223 , G01N2333/195 , G01N2405/00 , G01N2405/04 , G01N2405/08 , G01N2570/00 , G01N2800/26 , G06F19/324 , G06F19/3481 , G16B20/00 , G16H10/40 , G16H15/00 , G16H50/20 , H01J49/0004 , H01J49/0027 , H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/0404 , H01J49/0409 , H01J49/0422 , H01J49/044 , H01J49/0445 , H01J49/0459 , H01J49/0463 , H01J49/0468 , H01J49/061 , H01J49/068 , H01J49/10 , H01J49/14 , H01J49/16 , H01J49/164 , H01J49/24 , H01J49/26
摘要： A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed. The method comprises: using a first device to generate smoke, aerosol or vapour from a target comprising or consisting of a microbial population; mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and analysing said spectrometric data in order to analyse said microbial population.

70. 发明申请

US20180038838A1 Collision Surface for Improved Ionisation 审中-公开
公开(公告)号：US20180038838A1
公开(公告)日：2018-02-08
申请号：US15555845
申请日：2016-03-07
申请人： Micromass UK Limited
发明人： Tamás KARANCSI , Dániel SIMON , Lajos GÖDÖRHÁZY , Dániel SZALAY , Steven Derek PRINGLE , Emrys JONES , Ian TRIVETT , Stephen O'BRIEN , Anthony HESSE , Matt HENDERSON , Alvin CHUA , Zoltan TAKÁTS
IPC分类号： G01N30/72 , G01N3/00 , G01N33/92 , A61B18/14 , H01J49/00 , H01J49/04 , H01J49/06 , H01J49/16 , G01N33/68 , G01N9/00
CPC分类号： H01J49/049 , A61B1/2736 , A61B5/00 , A61B5/0507 , A61B5/14546 , A61B5/7264 , A61B10/00 , A61B10/0041 , A61B10/0233 , A61B10/0283 , A61B17/320068 , A61B18/04 , A61B18/042 , A61B18/14 , A61B18/1815 , A61B18/20 , A61B2010/0083 , A61B2017/32007 , A61B2018/00577 , A61B2018/00589 , A61B2018/00994 , A61B2218/002 , A61B2218/008 , A61B2505/05 , C12Q1/025 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/2202 , G01N3/00 , G01N9/00 , G01N27/622 , G01N27/624 , G01N27/626 , G01N30/724 , G01N33/6848 , G01N33/6851 , G01N33/92 , G01N2001/2223 , G01N2333/195 , G01N2405/00 , G01N2405/04 , G01N2405/08 , G01N2570/00 , G01N2800/26 , G16H10/40 , G16H20/00 , G16H50/20 , H01J49/0027 , H01J49/0404 , H01J49/0459 , H01J49/0463 , H01J49/0468 , H01J49/068 , H01J49/16
摘要： An apparatus for performing ambient ionisation mass and/or ion mobility spectrometry is disclosed. The apparatus comprises a substantially cylindrical, tubular, rod-shaped, coil-shaped, helical or spiral-shaped collision assembly; and a first device arranged and adapted to direct analyte, smoke, fumes, liquid, gas, surgical smoke, aerosol or vapour onto said collision assembly.

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