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61. 发明授权

US10485995B2 Compact lightweight high-performance proton therapy beamline 有权
公开(公告)号：US10485995B2
公开(公告)日：2019-11-26
申请号：US15392999
申请日：2016-12-28
申请人： Varian Medical Systems, Inc. , Varian Medical Systems Particle Therapy GmbH
发明人： Vladimir Anferov , Alexander Winnebeck
IPC分类号： A61N5/00 , A61N5/10 , H05H7/00 , H05H7/04
CPC分类号： A61N5/1077 , A61N5/00 , H05H7/001 , H05H7/04 , A61N5/1081 , A61N2005/1087 , H05H2007/002 , H05H2007/007 , H05H2007/048
摘要： A compact lightweight gantry for a proton therapy system that has a source-to-axis distance (SAD) of less than 2 m and can deliver a proton beam of superior quality. The reduced SAD leads to reduced requirements on the maximum magnetic fields that can be generated by the bend magnets in the gantry beamline. Correspondingly, lightweight bend magnets can be used. The various components in the gantry beamline are optimized to achieve a beam spot size of approximately 4 mm sigma or less through a pencil beam scanning nozzle disposed downstream of the final bending magnet. In addition, the proton therapy system is configured to operate at a maximum beam energy in the range of 220-230 MeV.

62. 发明申请

US20180326226A1 PARTICLE THERAPY SYSTEM 审中-公开
公开(公告)号：US20180326226A1
公开(公告)日：2018-11-15
申请号：US15963281
申请日：2018-04-26
申请人： Hitachi, Ltd.
发明人： Fuutarou EBINA , Takamichi AOKI
IPC分类号： A61N5/10 , H05H13/04 , H05H7/00 , H05H7/04
CPC分类号： A61N5/1081 , A61N5/1049 , A61N2005/1087 , H05H7/001 , H05H7/04 , H05H13/04 , H05H2007/002 , H05H2007/008 , H05H2007/043 , H05H2007/048 , H05H2277/11
摘要： [Problem]A particle therapy system capable of reducing the installation area and also suppressing a variation in the irradiation beam position is provided. A synchrotron generates a charged particle beam, and a beam delivery system irradiates an irradiation target with a charged particle beam extracted from the synchrotron thereby forming a radiation field. A rotating gantry is provided with the beam delivery system and is rotatable around the irradiation target. Dispersion measuring devices, each of which measures the dispersion of the charged particle beam at the position of the irradiation target at a plurality of rotation angles of the rotating gantry, are also provided. The orbit center of the charged particle beam extracted from the synchrotron and the rotation axis of the rotating gantry are located on substantially the same straight line.

63. 发明授权

US09661736B2 Scanning system for a particle therapy system 有权
公开(公告)号：US09661736B2
公开(公告)日：2017-05-23
申请号：US14184990
申请日：2014-02-20
申请人： Mevion Medical Systems, Inc.
发明人： Charles D. O'Neal, III , Adam C. Molzahn
IPC分类号： A61N5/10 , H05H13/02 , H05H7/00 , H05H7/04
CPC分类号： A61N5/103 , A61N5/1043 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1067 , A61N5/1071 , A61N5/1081 , A61N2005/1085 , A61N2005/1087 , H05H7/04 , H05H13/02 , H05H13/04 , H05H2007/002 , H05H2007/004 , H05H2007/048
摘要： An example particle therapy system includes: a particle accelerator to output a beam of charged particles; and a scanning system to scan the beam across at least part of an irradiation target. An example scanning system includes: a scanning magnet to move the beam during scanning; and a control system (i) to control the scanning magnet to produce uninterrupted movement of the beam over at least part of a depth-wise layer of the irradiation target so as to deliver doses of charged particles to the irradiation target; and (ii) to determine, in synchronism with delivery of a dose, information identifying the dose actually delivered at different positions along the depth-wise layer.

64. 发明授权

US09630027B2 Beam transport system and particle beam therapy system 有权
公开(公告)号：US09630027B2
公开(公告)日：2017-04-25
申请号：US14891922
申请日：2013-07-11
申请人： MITSUBISHI ELECTRIC CORPORATION
发明人： Kazushi Hanakawa , Kengo Sugahara , Shuhei Odawara
IPC分类号： A61N5/10 , H05H7/04 , H05H7/00
CPC分类号： A61N5/1064 , A61N5/1077 , A61N2005/1087 , H05H7/001 , H05H7/04 , H05H2007/002 , H05H2007/048
摘要： In a beam transport system, based on a beam temporal-variation related amount that has been calculated by a beam analyzer and that is a beam-position temporal variation amount or a beam diameter at a beam profile monitor, an optical parameter calculator calculates a start-point momentum dispersion function that is a momentum dispersion function (η, η′) of a charged particle beam at a start point in design of the beam transport system that is set on a beam trajectory of the accelerator; and calculates optical parameters using, as an initial condition, the start-point momentum dispersion function and a beginning condition at an irradiation position at the time of detecting profile data.

65. 发明申请

US20150328483A1 PARTICLE THERAPY APPARATUS 审中-公开
标题翻译：颗粒治疗装置
公开(公告)号：US20150328483A1
公开(公告)日：2015-11-19
申请号：US14653185
申请日：2013-02-22
申请人： MITSUBISHI ELECTRIC CORPORATION
发明人： Shuhei ODAWARA , Hisashi HARADA , Masahiro IKEDA , Kengo SUGAHARA
IPC分类号： A61N5/10
CPC分类号： A61N5/1081 , A61N2005/1087 , H05H7/04 , H05H2007/008 , H05H2007/046 , H05H2007/048
摘要： A particle therapy apparatus has a rotating gantry configured in such a way that an irradiation device is rotated around a rotation axis and a particle beam is irradiated onto an irradiation subject; the rotating gantry is provided with an entrance-side deflection electromagnet having a deflection path for radially deflecting the particle beam supplied along the rotation axis so as to guide the particle beam to the irradiation device and a straight path that is switchable with the deflection path and is for making the supplied particle beam travel in a straight manner; there are provided trajectory correcting devices having two position sensors that are arranged along the rotation axis so as to flank the entrance-side deflection electromagnet.
摘要翻译：粒子治疗装置具有旋转台架，其构造为使得照射装置绕旋转轴线旋转，并且将粒子束照射到照射对象上; 旋转机架设置有入射侧偏转电磁体，该入射侧偏转电磁体具有用于使沿着旋转轴线供应的粒子束径向偏转的偏转路径，以将粒子束引导到照射装置，以及可与偏转路径切换的直线路径，用于使供应的粒子束以直线方式行进; 提供了具有两个位置传感器的轨迹校正装置，该位置传感器沿旋转轴线布置，以便在入口侧偏转电磁体的侧面。

66. 发明申请

US20140235922A1 PARTICLE BEAM TREATMENT SYSTEM AND BEAM POSITION CORRECTING METHOD THEREOF 有权
标题翻译：粒子束处理系统和光束位置校正方法
公开(公告)号：US20140235922A1
公开(公告)日：2014-08-21
申请号：US14346908
申请日：2012-09-21
申请人： Mitsubishi Electric Corporation
发明人： Kazushi Hanakawa , Kengo Sugahara , Shuhei Odawara , Hisashi Harada , Masahiro Ikeda , Toshihiro Otani , Taizo Honda , Katsuhisa Yoshida
IPC分类号： A61N5/10
CPC分类号： A61N5/1042 , A61N5/1043 , A61N5/1067 , A61N2005/1087 , H05H7/04 , H05H2007/048 , H05H2277/11
摘要： A particle beam treatment system includes an accelerator system that accelerates a charged particle beam and a beam transport system that transports a high-energy beam emitted from the accelerator to an irradiation location, wherein the beam transport system is provided with at least one steering electromagnet and at least one beam position monitor corresponding to the at least one steering electromagnet, and wherein the at least one beam position monitor supplies an excitation current for correcting a beam position, which periodically varies, to the at least one steering electromagnet.
摘要翻译：粒子束处理系统包括加速带电粒子束的加速器系统和将从加速器发射的高能束传送到照射位置的射束输送系统，其中光束输送系统设置有至少一个转向电磁铁，至少一个光束位置监视器，其对应于所述至少一个转向电磁体，并且其中所述至少一个光束位置监视器向所述至少一个转向电磁体提供用于校正周期性变化的光束位置的激励电流。

67. 发明授权

US08546769B2 Charged particle beam irradiation apparatus, charged particle beam irradiating method, and method of attaching and detaching transport line 失效
标题翻译：带电粒子束照射装置，带电粒子束照射方法以及安装和拆卸运输线的方法
公开(公告)号：US08546769B2
公开(公告)日：2013-10-01
申请号：US13293171
申请日：2011-11-10
申请人： Kouichi Uno
发明人： Kouichi Uno
IPC分类号： H01J3/26
CPC分类号： G21K5/04 , A61N5/1077 , A61N5/1079 , A61N2005/1087 , H05H7/04 , H05H2007/048
摘要： A charged particle beam irradiation apparatus includes an accelerator that accelerates the charged particle beam; a first transport line that transports the charged particle beam which is delivered from the accelerator; a plurality of second transport lines that may be provided for each of plurality of irradiation chambers and further transports the charged particle beam to be transported by the first transport line to the respective irradiation chambers; and a line switching unit that may be provided between the first transport line and the second transport lines, wherein the plurality of irradiation chambers may be radially disposed around the line switching unit, the line switching unit has an electromagnet that induces the charged particle beam, and a rotating mechanism that rotates the electromagnet, and the second transport lines of the induction place may be switched by rotating the electromagnet.
摘要翻译：带电粒子束照射装置包括加速带电粒子束的加速器; 输送从加速器输送的带电粒子束的第一输送线; 可以为多个照射室中的每一个设置多个第二输送线，并且将通过第一输送线输送的带电粒子束进一步输送到各个照射室; 以及可以设置在第一输送线和第二输送线之间的线切换单元，其中多个照射室可以围绕线切换单元径向地布置，线切换单元具有引起带电粒子束的电磁体，以及旋转电磁体的旋转机构，并且可以通过旋转电磁体来切换感应位置的第二输送线。

68. 发明申请

US20120119106A1 CHARGED PARTICLE BEAM IRRADIATION APPARATUS, CHARGED PARTICLE BEAM IRRADIATING METHOD, AND METHOD OF ATTACHING AND DETACHING TRANSPORT LINE 失效
标题翻译：充电颗粒光束辐射装置，充电颗粒光束辐射方法及连接和拆卸运输线的方法
公开(公告)号：US20120119106A1
公开(公告)日：2012-05-17
申请号：US13293171
申请日：2011-11-10
申请人： Kouichi UNO
发明人： Kouichi UNO
IPC分类号： H01J3/26
CPC分类号： G21K5/04 , A61N5/1077 , A61N5/1079 , A61N2005/1087 , H05H7/04 , H05H2007/048
摘要： A charged particle beam irradiation apparatus includes an accelerator that accelerates the charged particle beam; a first transport line that transports the charged particle beam which is delivered from the accelerator; a plurality of second transport lines that may be provided for each of plurality of irradiation chambers and further transports the charged particle beam to be transported by the first transport line to the respective irradiation chambers; and a line switching unit that may be provided between the first transport line and the second transport lines, wherein the plurality of irradiation chambers may be radially disposed around the line switching unit, the line switching unit has an electromagnet that induces the charged particle beam, and a rotating mechanism that rotates the electromagnet, and the second transport lines of the induction place may be switched by rotating the electromagnet.
摘要翻译：带电粒子束照射装置包括加速带电粒子束的加速器; 输送从加速器输送的带电粒子束的第一输送线; 可以为多个照射室中的每一个设置多个第二输送线，并且将通过第一输送线输送的带电粒子束进一步输送到各个照射室; 以及可以设置在第一输送线和第二输送线之间的线切换单元，其中多个照射室可以围绕线切换单元径向地布置，线切换单元具有引起带电粒子束的电磁体，以及旋转电磁体的旋转机构，并且可以通过旋转电磁体来切换感应位置的第二输送线。

69. 发明申请

US20190166681A1 METHOD FOR ADJUSTING PARTICLE ORBIT ALIGNMENT BY USING FIRST HARMONIC IN CYCLOTRON 审中-公开
公开(公告)号：US20190166681A1
公开(公告)日：2019-05-30
申请号：US16207216
申请日：2018-12-03
申请人： HEFEI CAS ION MEDICAL AND TECHNICAL DEVICES CO., LTD.
发明人： Yuntao SONG , Kaizhong DING , Jian GE , Kai ZHOU , Yonghua CHEN , Junjun LI , Hansheng FENG , Kun PEI , Jian ZHOU , Zhong WANG , Xinyu CHEN
IPC分类号： H05H7/04 , H05H13/00
CPC分类号： H05H7/04 , H05H13/005 , H05H2007/048
摘要： The invention discloses a method for adjusting particle orbit alignment by using a first harmonic in a cyclotron, including the following steps: generating a correcting magnetic field through eight coils symmetrically about the middle plane; arranging the positions of the coils and the currents applied, so that they can generate a first harmonic of which the amplitude and phase are arbitrarily adjustable; according to the actual eccentricity of the particle orbit, adjusting the magnitude and direction of the currents applied to the coils, and optimizing the alignment of the particle trajectory. By controlling an external DC power source of the accelerator and combining the real-time feedback of the beam detection of the accelerator, the invention may perform real-time adjustment during the debugging and operation of the accelerator, with high feasibility and operability; compared with traditional methods, the invention may achieve real-time adjustment during the debugging and operation of the accelerator.

70. 发明授权

US10016623B2 Particle therapy system and method with parallel control of energy variation and beam position variation 有权
公开(公告)号：US10016623B2
公开(公告)日：2018-07-10
申请号：US15375259
申请日：2016-12-12
申请人： Ion Beam Applications
发明人： Yves Claereboudt , Damien Prieels
IPC分类号： A61N5/10 , G21K5/04 , H05H7/04 , H05H13/00 , H05H13/02 , H05H13/04
CPC分类号： A61N5/1043 , A61N5/103 , A61N5/107 , A61N5/1081 , A61N2005/1076 , A61N2005/1087 , H05H7/04 , H05H13/005 , H05H13/02 , H05H13/04 , H05H2007/048 , H05H2245/122
摘要： The present disclosure relates to a particle therapy system for irradiating a target with a scanning beam technique. In one implementation, the system includes an irradiation planning device with a planning algorithm configured to associate a particle beam energy E(i) to each spot of the irradiation plan and organize the spots in a sequence of spots according to energy. The system may further include a control system configured for controlling in parallel, from spot to spot, a variation of an output energy of a beam generator, a variation of a magnetic field of one or more electromagnets of a beam transport system and a variation of a magnetic field of the scanning magnet.

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