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    • 61. 发明专利
    • Short coherence length doppler velocimetry system
    • SG50358A1
    • 1998-07-20
    • SG1995001530
    • 1995-10-11
    • ZEISS STIFTUNG
    • HELLMUTH THOMASPETERSEN CHRISTOPHER
    • A61B3/12A61B5/0285G01AA61B5/26A61B5/265
    • Apparatus for measuring the speed of blood in blood vessels in biological samples, for example, in retinal blood vessels, which apparatus includes: (a) a source (510) of a beam of radiation having a principal wavelength, which radiation is substantially spatially coherent and has a temporal coherence length which is less than 1 picosecond; (b) a beam splitter (530) for splitting the beam into a sample beam (550) and reference beam (549); (c) optical apparatus (570) for directing the sample beam to an area within the biological sample (588); (d) a reflector (560) for reflecting the reference beam; (e) a detector (580) for detecting an interference between the sample beam reflected from the area and the reflected reference beam and for generating an interference signal; (f) apparatus for altering an optical path length of the reference beam from the beam splitter to the detector at an alteration velocity; and (g) an analyzer (590) for analyzing the interference signal to determine the speed of the blood in the area from a shift of a central frequency of a frequency spectrum of the interference signal from a frequency determined from the alteration velocity and the principal wavelength.