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    • 76. 发明申请
    • RADIOTHERAPY UTILIZING THE ENTIRE 4PI SOLID ANGLE
    • 使用整个4PI固体角的放射治疗
    • WO2016140955A1
    • 2016-09-09
    • PCT/US2016/020234
    • 2016-03-01
    • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    • SHENG, KeRUAN, DanLOW, Dan A.
    • A61N5/10A61N5/00
    • A61N5/103A61N5/1047A61N5/1082A61N2005/1087A61N2005/1089A61N2005/109
    • In various embodiments, methods and devices are provided for generating a radiotherapy treatment plan for a subject to be implemented on a radiotherapy device. In certain embodiments the methods involve determining all feasible radiotherapy beam orientations free of collision for said radiotherapy device and said subject to provide a set of radiotherapy beam orientations; selecting from the set of all feasible radiotherapy beam orientations a subset of beams that meet treatment goals to be used in treatment of the subject to provide a selected beam set; calculating a navigation trajectory for the radiotherapy device to delivery said subset of beams to the subject where the trajectory is free of collision; and generating and writing instruction files to a tangible medium that can be executed by said radiotherapy device.
    • 在各种实施例中,提供了用于产生用于在放射治疗装置上实现的受试者的放射治疗计划的方法和装置。 在某些实施方案中,所述方法包括确定所有放射治疗装置和所述受试者的所有可行的放射治疗束取向不存在碰撞,以提供一组放射治疗束取向; 从所述可行放射治疗束定向的一组中选择满足待治疗目标以用于对象以提供所选择的束组的治疗目标的束子集; 计算放射治疗装置的导航轨迹,以将所述射束子集输送到所述对象,其中所述轨迹不存在碰撞; 以及向可由所述放射治疗装置执行的有形介质生成和写入指令文件。
    • 77. 发明申请
    • METHOD AND SYSTEM FOR STEREOTACTIC INTENSITY-MODULATED ARC THERAPY
    • 用于立体强度调制电弧疗法的方法和系统
    • WO2015103564A1
    • 2015-07-09
    • PCT/US2015/010197
    • 2015-01-05
    • YU, Xinsheng Cedric
    • YU, Xinsheng Cedric
    • A61N5/10A61B6/00
    • A61N5/1047A61B6/032A61B6/035A61B6/4429A61B6/4435A61B6/4441A61B6/4452A61N5/10A61N5/1036A61N5/1039A61N5/1048A61N5/1049A61N5/1067A61N5/107A61N5/1082A61N2005/1052A61N2005/1054A61N2005/1055A61N2005/1061
    • A method of irradiating a target in a patient comprising directing a beam of radiation from an external source of radiation 24 at the target in the patient from numerous directions in a broad solid angle by longitudinally rotating the external source of radiation 24 around a central axis and simultaneously or sequentially, in either order, latitudinally rotating the external source of radiation 24; a globe gantry 21 comprising (i) a front opening ring 22 with its origin on the central axis of the globe gantry 21, (ii) at least one arc-shaped, gantry support arm 23, which has a front end and a rear end and is part of a circle, (iii) an external source of radiation 24, which is mounted on at least one arc-shaped, gantry support arm 23 and is movable along the gantry support arm to vary the latitude of the beam angle, (iv) a rear rotational axle 25 with an axis along the central axis of the globe gantry 21, (v) a support base 27, and (vi) a rear housing 26 comprising a source of power, mechanisms for moving components of the globe gantry 21, and controllers for controlling the movement of the components of the globe gantry 21 and the irradiation of the target in the patient; a system 20 comprising the globe gantry 21; and a method of irradiating a target in a patient using the system.
    • 一种照射患者中的靶的方法,包括通过围绕中心轴线纵向旋转外部辐射源24,以宽广立体角度从多个方向将来自外部辐射源24的辐射束定向在患者的目标上,以及 同时或顺序地以任何顺序,横向旋转外部辐射源24; 地球台架21包括(i)其前端开口环22,其原点在球形台架21的中心轴线上,(ii)至少一个弧形的龙门架支撑臂23,其具有前端和后端 并且是圆的一部分,(iii)外部辐射源24,其安装在至少一个弧形的龙门架支撑臂23上,并且可沿着机架支撑臂移动以改变光束角的纬度( iv)具有沿着球形台架21的中心轴的轴线的后旋转轴25,(v)支撑基座27,以及(vi)包括动力源的后壳体26,用于移动地球台架的部件的机构 21,以及用于控制地球台架21的部件的移动和患者体内的靶的照射的控制器; 包括地球台架21的系统20; 以及使用该系统照射患者中的靶的方法。
    • 78. 发明申请
    • MEDICAL APPARATUS WITH A RADIATION THERAPY DEVICE AND A RADIATION DETECTION SYSTEM
    • 具有放射治疗装置和辐射检测系统的医疗装置
    • WO2015055473A1
    • 2015-04-23
    • PCT/EP2014/071485
    • 2014-10-08
    • KONINKLIJKE PHILIPS N.V.
    • VAHALA, Erkki TapaniAMTHOR, Thomas ErikFORTHMANN, Peter
    • A61N5/10
    • A61N5/1049A61B2090/374A61B2090/3954A61N5/1038A61N5/1039A61N5/1047A61N5/1067A61N5/1075A61N5/1081A61N2005/1052A61N2005/1054A61N2005/1055A61N2005/1059
    • The invention provides for a medical apparatus (100, 300, 400, 800) comprising a magnetic resonance imaging system (104), a radiation therapy device (102) comprising a gantry (106) and a radiation source (110), and a radiation detection system (102) operable for measuring radiation detection data (174) descriptive of the path and intensity of the radiation beam at the intersection of the radiation beam with at least one surface (144, 144', 144") surrounding the subject using at least one radiation detector (144, 144', 144"). Execution of machine readable instructions causes a processor controlling the medical apparatus to: receive (200) a treatment plan (168), acquire (202) magnetic resonance data (164) from the imaging zone using the magnetic resonance imaging system, generate (204) radiation therapy device control commands (172) using the magnetic resonance data and the treatment plan, irradiate (206) the target zone by controlling the radiation therapy device using the radiation therapy device control commands, measure (208) the radiation detection data during irradiation, and determine a time dependent radiation beam path (176) and a time dependent radiation beam intensity (178) using the radiation detection data.
    • 本发明提供一种包括磁共振成像系统(104)的医疗设备(100,300,400,800),包括台架(106)和辐射源(110)的辐射治疗设备(102)和辐射源 检测系统(102),其可操作用于测量辐射检测数据(174),所述辐射检测数据描述辐射束与所述对象周围的至少一个表面(144,144',144“)的相交处的辐射束的路径和强度, 至少一个辐射检测器(144,144',144“)。 机器可读指令的执行使得控制医疗设备的处理器:使用磁共振成像系统从处理计划(168)接收(200)磁共振数据(164),从成像区获取(202)磁共振数据(164),生成(204) 使用磁共振数据和治疗方案的放射治疗装置控制命令(172)通过使用放射线治疗装置控制指令控制放射线治疗装置照射(206)目标区域,在照射期间测量(208)放射线检测数据, 并且使用辐射检测数据确定时间相关的辐射束路径(176)和时间相关的辐射束强度(178)。
    • 79. 发明申请
    • AUTOMATIC OPTIMAL IMRT/VMAT TREATMENT PLAN GENERATION.
    • 自动优化IMRT / VMAT治疗计划生成。
    • WO2014068435A2
    • 2014-05-08
    • PCT/IB2013059440
    • 2013-10-18
    • KONINKL PHILIPS NV
    • KUMAR PRASHANTBZDUSEK KARL ANTONINPALMER MATTHEWKANTOR MICHAEL
    • G06F19/00
    • A61N5/1039A61N5/1031A61N5/1038A61N5/1042A61N5/1045A61N5/1047G06F19/3481
    • A therapy planning system (18) and method generate an optimal treatment plan. A plurality of objectives are automatically formulated (154) based on a plurality of clinical goals including dose profiles and priorities. The dose profiles and the priorities correspond to a plurality of structures including a plurality of target and/or critical structures identified within a planning image. Further, a plurality of treatment plan parameters are optimized (156) based on the plurality of objectives to generate a treatment plan. The plurality of objectives are reformulated (162) and the plurality of treatment plan parameters are reoptimized (156) based on the reformulated plurality of objectives to generate a reoptimized treatment plan. The optimizing (156) is repeated based on the reformulated plurality of objectives to generate a reformulated treatment plan.
    • 治疗计划系统(18)和方法产生最佳治疗计划。 基于多个临床目标(包括剂量简档和优先级)自动制定(154)多个目标。 剂量分布图和优先级对应于包括在计划图像内识别的多个目标和/或关键结构的多个结构。 此外,基于多个目标来优化(156)多个治疗计划参数以生成治疗计划。 重新制定多个目标(162),并基于重新制定的多个目标重新优化(156)多个治疗计划参数以生成重新优化的治疗计划。 基于重新制定的多个目标重复优化(156)以生成重新制定的治疗计划。