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81. 发明授权

US08785660B2 Polyoxyalkylene-modified lipid and method for producing the same 有权
标题翻译：聚氧化烯改性脂质及其制备方法
公开(公告)号：US08785660B2
公开(公告)日：2014-07-22
申请号：US13431590
申请日：2012-03-27
申请人： Satoshi Matsuo , Yuji Yamamoto , Chika Itoh
发明人： Satoshi Matsuo , Yuji Yamamoto , Chika Itoh
IPC分类号： C07D207/456
CPC分类号： C07D207/456 , C07C269/04 , C07C271/16 , C07D207/452
摘要： Provided are a thiol-reactive polyoxyalkylene-modified lipid which can be used to chemically modify bioactive substances and which can be used for drug delivery systems such as liposomes and a method for producing the same. The polyoxyalkylene-modified lipid is represented by the following formula (1): (wherein, R1 and R2 are hydrocarbon groups which are the same as or different from each other and which contain 4 to 24 carbon atoms, R3 is a divalent hydrocarbon group containing 1 to 6 carbon atoms, OA is oxyalkylene groups containing 2 to 4 carbon atoms, n is the average addition mole number of the oxyalkylene groups and is 5 to 1,000, and Z is a group containing either maleimide or iodoacetamide.)
摘要翻译：提供了可用于化学修饰生物活性物质并且可用于药物递送系统如脂质体的硫醇反应性聚氧化烯修饰的脂质及其制备方法。聚氧化烯修饰的脂质由下式（1）表示：（其中，R 1和R 2为彼此相同或不同且含有4〜24个碳原子的烃基，R 3为含有 1〜6个碳原子，OA为含有2〜4个碳原子的氧化烯基，n为氧化烯基的平均加成摩尔数，为5〜1000，Z为含有马来酰亚胺或碘乙酰胺的基团。

82. 发明申请

US20140048041A1 IN-CYLINDER PRESSURE DETECTING DEVICE OF DIRECT INJECTION TYPE INTERNAL COMBUSTION ENGINE 有权
标题翻译：直列式内燃机缸内压力检测装置
公开(公告)号：US20140048041A1
公开(公告)日：2014-02-20
申请号：US13985143
申请日：2012-02-20
申请人： Shusuke Akazaki , Yuji Yamamoto , Toshitaka Hachiro , Gaku Sato
发明人： Shusuke Akazaki , Yuji Yamamoto , Toshitaka Hachiro , Gaku Sato
IPC分类号： F02M69/00
CPC分类号： F02M69/00 , F02B23/104 , F02B2075/125 , F02D35/023 , F02M57/005 , F02M61/14 , F02M2200/247 , G01L23/10 , Y02T10/123 , Y02T10/125
摘要： An in-cylinder pressure detecting device of a direct injection type internal combustion engine is provided in which a ring-shaped pressure detection element (34) surrounding a fuel injection hole (33b) is provided in the vicinity of an extremity of an injector (20) that injects fuel into a combustion chamber. Since the pressure detection element is provided on the injector, not only is it unnecessary to change the shape or structure of the cylinder head or the combustion chamber in order to provide the pressure detection element, but it is also possible to cool the pressure detection element (34) by fuel passing through the inside of the injector to thus enhance the precision of pressure detection and the durability. Further, since the ring-shaped pressure detection element (34) surrounds the periphery of the fuel injection hole (33b), it is possible to maximize the dimensions of the pressure detection element (34) to thus further enhance the precision of pressure detection while avoiding interference between the pressure detection element (34) and fuel injected via the fuel injection hole (33b).
摘要翻译：提供一种直喷式内燃机的缸内压力检测装置，其中，在喷射器（20）的末端附近设置围绕燃料喷射孔（33b）的环状压力检测元件（34））将燃料喷射到燃烧室中。由于压力检测元件设置在喷射器上，为了提供压力检测元件，不仅不需要改变气缸盖或燃烧室的形状或结构，而且还可以将压力检测元件（34）通过喷射器内部的燃料，从而提高压力检测的精度和耐久性。此外，由于环状压力检测元件34围绕燃料喷射孔33b的周围，所以能够使压力检测元件34的尺寸最大化，能够进一步提高压力检测的精度，避免压力检测元件（34）与经由燃料喷射孔（33b）喷射的燃料之间的干扰。

83. 发明申请

US20130161869A1 METHOD OF MANUFACTURING FINE STRUCTURE BODY AND FINE STRUCTURE MOLD 有权
标题翻译：制造精细结构体和精细结构模具的方法
公开(公告)号：US20130161869A1
公开(公告)日：2013-06-27
申请号：US13821379
申请日：2012-04-26
申请人： Yuji Yamamoto , Toshihiko Wada , Yoshifumi Takasu , Akihisa Yamada
发明人： Yuji Yamamoto , Toshihiko Wada , Yoshifumi Takasu , Akihisa Yamada
IPC分类号： B29C59/02
CPC分类号： G03F7/0002 , B29C33/42 , B29C59/02 , B82Y10/00 , B82Y40/00
摘要： The present invention is a method of manufacturing a fine structure body which manufactures the fine structure body by repeating a basic fine structure body forming step that forms a basic fine structure body by pressing a fine structure mold against a curable resin (photocurable resin film) on a surface of a base material and a release and moving step that releases the fine structure mold from the base material and moves the fine structure mold, wherein the fine structure mold includes at least a first mold depression pattern which is disposed at center area of it, and a second mold depression pattern which is disposed in at least one side part in circumference area of it, and a size of the second mold depression pattern is smaller than a size of the first mold depression pattern.
摘要翻译：本发明是一种制造精细结构体的方法，该精细结构体通过重复通过将精细结构模具压在固化树脂（光固化树脂膜）上而形成基本精细结构体的基本细微结构体形成步骤基材的表面和释放和移动步骤，从基材释放精细结构模具并移动精细结构模具，其中精细结构模具至少包括设置在其中心区域的第一凹陷图案以及设置在其圆周区域中的至少一个侧部中的第二凹陷图案，并且第二凹陷图案的尺寸小于第一凹陷图案的尺寸。

84. 发明申请

US20130113995A1 DIGITAL BROADCAST RECEIVER UNIT 有权
公开(公告)号：US20130113995A1
公开(公告)日：2013-05-09
申请号：US13731215
申请日：2012-12-31
申请人： Satoru TAKASHIMIZU , Kenji KATSUMATA , Yuji YAMAMOTO , Satoshi IIMURO , Takanori EDA , Shuko SEI
发明人： Satoru TAKASHIMIZU , Kenji KATSUMATA , Yuji YAMAMOTO , Satoshi IIMURO , Takanori EDA , Shuko SEI
IPC分类号： H04N5/44
CPC分类号： H04N21/4347 , H04N5/4401 , H04N5/46 , H04N21/42638 , H04N21/43637 , H04N21/4382 , H04N21/4385
摘要： Digital broadcast receiving apparatus including: a receiver receiving at least three different video programs in one transport stream, including a plurality of different video signal formats having different combination of scan lines and scan method; an isolator to isolate a video signal; a decoder to decode the video signal; a processor to execute a plurality of video processing sub software programs, providing video processing according to a different combination of the number of scan lines and a scan method; a controller using information obtained from the digital multiplexed signal to determine a combination of the number of scan lines and a scan method, and selecting one video processing of the video processing sub software programs to perform video processing according to the determined combination of the number of scan lines and the scan method; and a display to display the video signal processed by the processor.

85. 发明申请

US20130085152A1 Method For Assay On The Effect Of Vascularization Inhibitor 有权
标题翻译：血管化抑制剂作用的方法
公开(公告)号：US20130085152A1
公开(公告)日：2013-04-04
申请号：US13624278
申请日：2012-09-21
申请人： Junji Matsui , Yuji Yamamoto , Toshimitsu Uenaka
发明人： Junji Matsui , Yuji Yamamoto , Toshimitsu Uenaka
IPC分类号： A61K31/517 , A61K31/47
CPC分类号： A61K31/517 , A61K31/47 , G01N33/5011 , G01N33/574 , G01N2333/485 , G01N2333/515
摘要： The present invention provides a method of predicting the antitumor effect of an angiogenesis inhibitor. It is possible to predict the antitumor effect of an angiogenesis inhibitor by evaluating the EOF dependency of a tumor cell for proliferation and/or survival and using the EGF dependency as an indicator. Since the antitumor effect of an angiogenesis inhibitor correlates with the EGF dependency of a tumor cell for proliferation and/or survival, the angiogenesis inhibitors is capable of producing excellent antitumor effect when combined with a substance having EGF inhibitory activity.
摘要翻译：本发明提供一种预测血管生成抑制剂的抗肿瘤作用的方法。通过评估肿瘤细胞的增殖和/或存活的EGF依赖性并使用EGF依赖性作为指标，可以预测血管发生抑制剂的抗肿瘤作用。由于血管生成抑制剂的抗肿瘤作用与肿瘤细胞对增殖和/或存活的依赖性相关，所以当与具有EGF抑制活性的物质组合时，血管生成抑制剂能够产生优异的抗肿瘤作用。

86. 发明授权

US08345168B2 Digital broadcast receiver unit 有权
标题翻译：数字广播接收机单元
公开(公告)号：US08345168B2
公开(公告)日：2013-01-01
申请号：US13022971
申请日：2011-02-08
申请人： Satoru Takashimizu , Kenji Katsumata , Yuji Yamamoto , Satoshi Iimuro , Takanori Eda , Shuko Sei
发明人： Satoru Takashimizu , Kenji Katsumata , Yuji Yamamoto , Satoshi Iimuro , Takanori Eda , Shuko Sei
IPC分类号： H04N7/01
CPC分类号： H04N21/4347 , H04N5/4401 , H04N5/46 , H04N21/42638 , H04N21/43637 , H04N21/4382 , H04N21/4385
摘要： A display apparatus coupled with a video processing apparatus including: an input unit which inputs a video signal scanned by one of the plurality of scanning methods and a scanning method data detected based on said video signal from said video processing apparatus, a display which displays said video signal inputted by said input unit, a controller which controls as said display displays said video signal based on said scanning method data inputted by said input unit.
摘要翻译：一种与视频处理装置耦合的显示装置，包括：输入单元，其输入通过所述多个扫描方法之一扫描的视频信号和基于来自所述视频处理装置的所述视频信号检测的扫描方法数据;显示器，其显示所述由所述输入单元输入的视频信号，控制器，其基于由所述输入单元输入的所述扫描方法数据，控制所述显示器显示所述视频信号。

87. 发明申请

US20120297350A1 CHIP SIZE ESTIMATING APPARATUS FOR SEMICONDUCTOR INTEGRATED CIRCUIT AND CHIP SIZE ESTIMATING METHOD FOR SEMICONDUCTOR INTEGRATED CIRCUIT 审中-公开
标题翻译：用于半导体集成电路的半导体集成电路和芯片尺寸估算方法的芯片尺寸估计装置
公开(公告)号：US20120297350A1
公开(公告)日：2012-11-22
申请号：US13365063
申请日：2012-02-02
申请人： Yuji Yamamoto
发明人： Yuji Yamamoto
IPC分类号： G06F17/50
CPC分类号： G06F17/504
摘要： A chip size estimating apparatus for a semiconductor integrated circuit of an embodiment has an input section configured to input a minimum number of functional gates that is a minimum number of gates necessary for realization of a function of a circuit, a set value holding section in which a performance-considered number-of-gates coefficient that is a ratio of a number of gates to be necessary for achievement of a predetermined operation speed to the minimum number of functional gates is set in advance for each cell library, and a calculating section configured to estimate a total area of the circuit by using a number of gates that is calculated from the minimum number of functional gates and the performance-considered number-of-gates coefficient.
摘要翻译：实施例的半导体集成电路的芯片尺寸估计装置具有：输入部，被配置为输入作为实现电路的功能所需的最小门数的功能门的最小数量;设定值保持部，其中，预先为每个单元库预先设定作为对实现预定操作速度所需的门数与最小功能门数的比值的性能考虑的门数系数，以及计算部件通过使用从功能门的最小数量和性能考虑的门数系数计算的多个门来估计电路的总面积。

88. 外观设计

USD658023S1 Portable electric sander 有权
标题翻译：便携式电动砂光机
公开(公告)号：USD658023S1
公开(公告)日：2012-04-24
申请号：US29403953
申请日：2011-10-13
申请人： Yuji Yamamoto , Fumihide Sugita
设计人： Yuji Yamamoto , Fumihide Sugita

89. 外观设计

USD655991S1 Engine hedge trimmer 有权
标题翻译：发动机树篱修剪机
公开(公告)号：USD655991S1
公开(公告)日：2012-03-20
申请号：US29365670
申请日：2010-07-13
申请人： Yuji Yamamoto , Koji Watanabe , Tomoaki Sato
设计人： Yuji Yamamoto , Koji Watanabe , Tomoaki Sato

90. 发明授权

US08003117B2 Polyalkylene glycol derivative and modified bio-related substance 有权
标题翻译：聚亚烷基二醇衍生物和改性生物相关物质
公开(公告)号：US08003117B2
公开(公告)日：2011-08-23
申请号：US11142678
申请日：2005-06-02
申请人： Ken-ichiro Nakamoto , Syunsuke Ohashi , Yuji Yamamoto , Kenji Sakanoue , Chika Itoh , Tohru Yasukohchi
发明人： Ken-ichiro Nakamoto , Syunsuke Ohashi , Yuji Yamamoto , Kenji Sakanoue , Chika Itoh , Tohru Yasukohchi
IPC分类号： C07C41/00 , C07C43/00
CPC分类号： C08G65/333 , C08G65/2609 , C08G65/329
摘要： A polyalkylene glycol derivative containing a compound of the formula (1): wherein R is a hydrocarbon group having 1 to 24 carbon atoms, OA2 is an oxyalkylene group having 2 to 4 carbon atoms, the groups represented by R are the same or different from each other in one molecule, the groups represented by OA2 are the same or different from each other in one molecule, m is an average number of moles of the oxyalkylene group added, m represents 10 to 1000, and X represents a functional group capable of chemically reactive with a bio-related substance, polydispersity Mw/Mn of the above polyalkylene glycol derivative in gel permeation chromatography satisfying the following relationship: Mw/Mn≦1.07 wherein Mw represents a weight average molecular weight and Mn represents a number average molecular weight.
摘要翻译：含有式（1）化合物的聚亚烷基二醇衍生物：其中R为碳原子数1〜24的烃基，OA2为碳原子数2〜4的氧化烯基，由R表示的基团相同或不同，在一个分子中，由一个分子表示的基团彼此相同或不同，m是加成的氧化烯基的平均摩尔数，m表示10〜1000，X表示能够与生物相关物质化学反应，上述聚亚烷基二醇衍生物的多分散性Mw / Mn在凝胶渗透色谱中满足以下关系式：Mw / Mn＆nlE 1.07其中Mw表示重均分子量，Mn表示数均分子量。

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