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1. 发明申请

WO2023031325A1 A DEVICE FOR SIMULATING A BRAKE 审中-公开
公开(公告)号：WO2023031325A1
公开(公告)日：2023-03-09
申请号：PCT/EP2022/074308
申请日：2022-09-01
申请人： SIMTAG
发明人： ZSINOR, Janos
IPC分类号： B60T7/04 , B60T8/40
摘要： The invention provides a device (100) for simulating a brake. The device (100) comprises a hydraulic cylinder (110). The hydraulic cylinder (110) comprises an inlet port (113) for being connected to a hydraulic fluid source (194), a piston (120) which is moveable inside the hydraulic cylinder (110) in response to hydraulic fluid flowing in and out of the hydraulic cylinder (110) via the inlet port (113), and a piston rod (121) connected to the piston (120). The piston rod (121) extends out of the hydraulic cylinder (110) at a first end (111) of the hydraulic cylinder (110). The hydraulic cylinder (110) is configured for moving the piston rod (121) respectively in an outwards and inwards direction in response to hydraulic fluid flowing in and out the hydraulic cylinder (110) via the inlet port (113). The device (100) comprises a first seating surface (141) opposite of the first end (111) of the hydraulic cylinder (110). The device (100) comprises a resilient element (150) arranged between an external end (123) of the piston rod (121) and the first seating surface (141).

2. 发明申请

WO2023280791A1 PROCEDE DE PRODUCTION DE BACTERIOPHAGES 审中-公开
公开(公告)号：WO2023280791A1
公开(公告)日：2023-01-12
申请号：PCT/EP2022/068487
申请日：2022-07-04
申请人： VESALE BIOSCIENCE
发明人： QUINTENS, Johan , PIRNAY, Jean-Paul , BLASDEL, Bob , LIENART VAN LIDTH DE JEUDE, Jehan
IPC分类号： C12N7/00 , A61K35/76
摘要： Procédé de production de bactériophages comprenant: fournir au moins une chambre de culture cellulaire; fournir un premier réservoir contenant un milieu de culture étant en première connexion en circuit fermé avec ladite au moins une chambre de culture cellulaire, le milieu de culture comprenant au moins une souche de phages et au moins une souche de bactéries; transférer le milieu de culture du premier réservoir via la première connexion en circuit fermé dans ladite au moins une chambre de culture cellulaire pour déposer le milieu de culture sous la forme d'une couche de culture dans ladite au moins une chambre de culture, incuber le milieu de culture pour propager des phages; fournir un récipient qui est en deuxième connexion en circuit fermé avec ladite au moins une chambre de culture cellulaire, la deuxième connexion en circuit fermé comprenant un système de filtration entre ladite au moins une chambre de culture cellulaire et le récipient; et transférer le milieu de culture comprenant les phages propagés depuis ladite au moins une chambre de culture vers la deuxième connexion en circuit fermé et purifier lesdits phages propagés via le système de filtration, le milieu de culture étant sous forme liquide lors du transfert depuis ladite au moins une chambre de culture vers la deuxième connexion en circuit fermé et de la purification.

3. 发明申请

WO2022263281A1 MONITORING THE ELECTRICAL SIGNAL BETWEEN AN ETCS LINESIDE ELECTRICAL UNIT AND ITS TRACKSIDE BALISE IN A RAILWAY ENVIRONMENT 审中-公开
公开(公告)号：WO2022263281A1
公开(公告)日：2022-12-22
申请号：PCT/EP2022/065672
申请日：2022-06-09
申请人： ERTMS SOLUTIONS
发明人： FERNANDES, Emmanuel
IPC分类号： B61L3/12 , B61L27/53 , B61L27/20
摘要： The present invention relates the monitoring an electrical signal (10) in a cable (90) between an electric unit (91) and a balise (92) in a railway installation (9). The first part (11) and the second part (12) of the electrical signal (10) are copied, and their copies (21, 22) are analyzed to determine a process output (55) based on the telegram signal (111) of the first part (11), and/or the sinusoidal signal (116) of the first part (11), and/or, the telegram signal (121) of the second part (12), and/or the sinusoidal signal (126) of the second part (12).

4. 发明申请

WO2022228682A1 TUNNEL TYPE DISINFECTION SYSTEM 审中-公开
公开(公告)号：WO2022228682A1
公开(公告)日：2022-11-03
申请号：PCT/EP2021/061285
申请日：2021-04-29
申请人： AGOP HAVLUCIYAN X-RAY GUVENLIK SISTEMLERI MERK. SAN. TIC. LTD. STI.
发明人： OZDEMIR, Murat
IPC分类号： A61L2/10 , A61L2/24 , B65B55/08
摘要： A baggage disinfection system (100) forming a tunnel (101) with at least twelve UVC emitting light bulbs is provided. The system (100) has a roller assembly (140) operated by a motor that causes the roller assembly (140) to convey objects at a rate of between about 0.10 m/second and about 0.50 m/second from an entry end of the system (100) to an exit end of the system (100), such that the travel time between the entry end of the system (100) and the exit end of the system (100) is less than or equal to about 30 seconds. In one embodiment, the system (100) is capable of inactivating at least 99.9% of Sars-Cov-2 viruses passing through the tunnel (101) within the travel time. In another embodiment, the system (100) is capable of inactivating at least 99.99% of Sars-Cov-2 or mutations thereof. In other embodiments, the travel time is less than about 10 seconds or less than about 8 seconds, and the system (100) is capable of inactivating at least 99.9% of Sars-Cov-2 or mutations thereof passing through the tunnel (101) within those travel times, or 99.99% of Sars-Cov-2 or mutations thereof passing through the tunnel (101) within those travel times. The system (100) is capable of inactivating 99.9% or 99.99% of viruses, including influenza viruses and coronaviruses, including without limitations, SARS, MERS and Sars-Cov-2 or mutations thereof.

5. 发明申请

WO2022200264A1 DISPOSITIF MICROFLUIDIQUE ROTATIF 审中-公开
公开(公告)号：WO2022200264A1
公开(公告)日：2022-09-29
申请号：PCT/EP2022/057335
申请日：2022-03-21
申请人： UNISENSOR
发明人： GRANIER, Benoît , NIVARLET, Noan , DAUBE, Simon , STRAAT, Julien
IPC分类号： B01L3/00 , B01L9/00
摘要： La présente invention concerne un dispositif microfluidique (100) rotatif comprenant deux valves (312, 322) séparées par une localisation intermédiaire (320) configurée pour une première fonction qui nécessite d'y maintenir le liquide pendant une première durée. Le dispositif microfluidique (100) est tel que la valve amont (312) s'ouvre à une première vitesse et la valve aval (322) s'ouvre à une deuxième vitesse, supérieure ou égale à la première vitesse. Ainsi, il est possible de maintenir le liquide dans la localisation intermédiaire (320) pendant une première durée en contrôlant la vitesse de rotation du dispositif microfluidique (100) rotatif.

6. 发明申请

WO2022200186A1 LIGHTING FOR UNDERWATER USE 审中-公开
公开(公告)号：WO2022200186A1
公开(公告)日：2022-09-29
申请号：PCT/EP2022/057073
申请日：2022-03-17
申请人： PROPULSION SYSTEMS
发明人： LAMBERTS, Marc
IPC分类号： F21V23/00 , F21V29/56 , F21V29/83 , F21V31/00 , F21V31/04 , H05K3/28 , F21W121/02 , F21W131/401
摘要： Lighting for underwater use The invention provides a pool lighting (100) comprising a housing (200) with front and back portion (210, 220) enclosing an internal volume (230). At least part of the front portion (210) is optically transparent. The lighting (100) comprises a PCB (300) with substrate layer (310), and at least one light source (320) on a substrate layer (310) front side (311). The PCB (300) is arranged in the internal volume (230) with the front and back side (312) facing towards the front and back portion (210, 220). The housing (200) is provided with at least one first opening (221) allowing water to enter the internal volume (230) and have contact with the PCB (300). The at least one light source (320) is sealed off from contact with water. The lighting (100) comprises an optically transparent electrically insulating waterproof first seal (400) covering at least the at least one light source (320) for sealing it off from contact with water. The front portion (210) of the housing is glued against the PCB (300) by means of the first seal (400).

7. 发明申请

WO2022175557A1 TREATMENT OF AQUATIC ANIMALS 审中-公开
公开(公告)号：WO2022175557A1
公开(公告)日：2022-08-25
申请号：PCT/EP2022/054439
申请日：2022-02-22
申请人： RIMFROST TECHNOLOGIES AS
发明人： BRUHEIM, Inge , SLINNING, Karl-Erik
IPC分类号： A23J1/04 , A23K10/22 , A23K50/80 , A23J3/34 , A23K40/20 , A23K40/25 , A23K40/30
摘要： The present invention relates to a method for the treatment of aquatic animals, such as fish or prawns, in particular for the purpose of improving the bodyweight gain of the animals or for the purpose of reducing the conversion ratio of the feed used to feed the aquatic animals without reducing their bodyweight gain. The present invention further relates to feed compositions, methods for their production and uses thereof.

8. 发明申请

WO2022122817A1 METHOD FOR PRODUCING A FERMENTATION PRODUCT 审中-公开
公开(公告)号：WO2022122817A1
公开(公告)日：2022-06-16
申请号：PCT/EP2021/084781
申请日：2021-12-08
申请人： CALIDRIS BIO [BE]/[BE]
发明人： VANLERBERGHE, Brecht, Marcel , DE BRUYN, Frederik, Benoit, Alphonsine , HOFLACK, Lieve, Monique, Cornelia , GHEERAERT, Johan, Hilaire, Corneel
IPC分类号： C12N1/00 , C12N1/16 , C12N1/20 , C12M1/107 , C12M1/00
摘要： The present invention relates to a method for producing a fermentation product, which method comprises (i) reducing carbon dioxide to a C1 compound, (ii) contacting at least a portion of said C1 compound with a culture comprising a methylotrophic microorganism, (iii) fermenting said C1 compound with said methylotrophic microorganism to produce said fermentation product, wherein the fermentation of the C1 compound with said methylotrophic microorganism further produces carbon dioxide, which is at least partially recycled to the reducing step.

9. 发明申请

WO2022117572A2 AN LTBR AGONIST IN COMBINATION THERAPY AGAINST CANCER 审中-公开
公开(公告)号：WO2022117572A2
公开(公告)日：2022-06-09
申请号：PCT/EP2021/083595
申请日：2021-11-30
申请人： ONCURIOUS NV
发明人： BERGERS, Gabriele , ALLEN, Elizabeth , DOMBRECHT, Bruno , MERCHIERS, Pascal
IPC分类号： C07K16/28 , A61P35/00 , A61K39/00 , A61K2039/505 , A61K2039/507 , C07K16/2866 , C07K16/2878 , C07K2317/22 , C07K2317/31 , C07K2317/35 , C07K2317/52 , C07K2317/569 , C07K2317/64 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to a combination comprising a Treg depletor and an LTBR agonist. Such a combination is particularly useful for use in the treatment of a cancer. Exemplified is the generation of mouse antagonist CCR8 VHH and of CCR8 VHH-Fc fusions as well as the generations of LTBR agonistic single domain antibodies. One anti-CCR8 antibody VHH-Fc and one LTBR agonist VHH have been tested in an MC38 syngeneic mouse model and shown to allow 100% of the tested mice to survive after 25 days, versus 60% with the VHH binding LTBR and 70% with the VHH- Fc binding CCR8. Also exemplified is the effect of a combination of an anti-CTLA4 antibody and a LTBR agonist (VHH-16) on tumor growth im an MC38 syngeneic mouse model resulting in synergism in reducing tumor burden.

10. 发明申请

WO2022029185A1 PROCESS FOR CRACKING A POLYOLEFIN CONTAINING MATERIAL 审中-公开
公开(公告)号：WO2022029185A1
公开(公告)日：2022-02-10
申请号：PCT/EP2021/071786
申请日：2021-08-04
申请人： INDAVER
发明人： ALDERWEIRELDT, Nick , KRESOVIC, Uros
IPC分类号： C10G1/10 , C10B53/07 , B01J19/00 , C10B57/02
摘要： The polyolefin containing waste material is thermally cracked to be converted into gaseous cracking products and into a solid residue (50). The material is cracked stepwise in a series of at least two successive cracking reactors (12, 35, 36) which each contain a liquid phase (13, 37, 46) and a gaseous phase (15, 39, 48). The first cracking reactor (12) is fed with the polyolefin containing material whilst the next cracking reactors are each fed with liquid phase from a previous cracking reactor. The temperature in the final cracking reactor (36) is higher than in the first cracking reactor (12) to crack also the thermally more stable polymers present in the waste material in the final reactor. By the lower temperature in the first reactor (12) production of non-condensable gases, which are of less value than the naphtha or wax fraction, can be minimized. The amount of more valuable wax in the gaseous product can be increased by applying a higher pressure in the first reactor. To be able to achieve a residue (50) which is completely solid, feeding of liquid phase (37) into the final cracking reactor (36) is interrupted at predetermined points in time until the liquid phase (46) contained in said final cracking reactor (36) is converted into a solid residue (50).

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