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    • 5. 发明专利
    • Irritation mitigating polymers and uses therefor
    • 激励缓和聚合物及其用途
    • JP2014156610A
    • 2014-08-28
    • JP2014096074
    • 2014-05-07
    • Lubrizol Advanced Materials Incルブリゾル アドバンスド マテリアルズ, インコーポレイテッド
    • KRISHNAN TAMARESELVYWILLIAM F MASLER IIIDEBORAH S FILLAGARY GRAY
    • C11D3/37A61K8/06A61K8/81C08F8/00C08F220/04
    • C11D3/3765C08F8/44C08F265/04C08F290/062C08L51/003C08F22/02C08F20/06C08L2666/02
    • PROBLEM TO BE SOLVED: To provide a non-crosslinked, linear acrylic copolymer that mitigates the ocular and dermal irritation typically associated with surfactant containing compositions without substantially affecting the rheological properties of such surfactant containing compositions.SOLUTION: A method for increasing the efficacy of hydrophobically modified (meth)acrylic based polymers to increase the critical micelle concentration of a surfactant composition by attenuating the degree of neutralization (DN) of the polymer is disclosed. Exemplary embodiments in accordance with the present invention are directed to a non-crosslinked, linear acrylic copolymer that mitigates the ocular and dermal irritation typically associated with surfactant containing compositions without substantially affecting the rheological properties of such surfactant containing compositions. The non-crosslinked, linear polymers are low molecular weight polymers having a number average molecular weight (M) of 100,000 or less as measured by gel permeation chromatography calibrated with a poly(methyl methacrylate) standard.
    • 要解决的问题:提供一种非交联的线型丙烯酸共聚物,其减轻通常与含表面活性剂的组合物相关的眼部和皮肤刺激,而基本上不影响这种含表面活性剂的组合物的流变性能。解决方案:提高疏水性功效的方法 公开了改性(甲基)丙烯酸系聚合物,以通过减弱聚合物的中和度(DN)来增加表面活性剂组合物的临界胶束浓度。 根据本发明的示例性实施方案涉及非交联的线型丙烯酸共聚物,其减轻通常与含表面活性剂的组合物相关的眼部和皮肤刺激,而基本上不影响这种含表面活性剂的组合物的流变性能。 非交联的线性聚合物是通过用聚(甲基丙烯酸甲酯)标准品校准的凝胶渗透色谱测量的数均分子量(M)为100,000或更小的低分子量聚合物。