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1. 发明授权

US3928642A Process for lysing mycelial waste 失效
标题翻译：裂解菌丝体废物的过程
公开(公告)号：US3928642A
公开(公告)日：1975-12-23
申请号：US54299075
申请日：1975-01-22
申请人： LILLY CO ELI
发明人： HUBERT ALFRED W , RUSSELL RALPH T
IPC分类号： C12N1/14 , A23K1/00 , A23K1/16 , C12F3/00 , C12N1/06
CPC分类号： C12N1/066 , A23K10/10 , C12F3/00
摘要： Mycelial waste is lysed by subjecting the waste to a temperature of from about 140* to about 200*C. at a pressure of from the equilibrium pressure to about 2,000 p.s.i.g., and at a pH of from about 2 to about 10. The lysed mycelial waste is useful as an animal feed supplement.
摘要翻译：通过使废物在平衡压力至约2000psig的压力和约2至约10的pH下经受约140至约200℃的温度而裂解菌丝体废物。裂解的菌丝体废物作为动物饲料补充剂是有用的。

2. 发明授权

US3928604A Arylacetylene compounds as antithrombotic agents 失效
标题翻译：芳基乙炔化合物作为抗血栓形成剂
公开(公告)号：US3928604A
公开(公告)日：1975-12-23
申请号：US48587774
申请日：1974-07-05
申请人： LILLY CO ELI
发明人： LACEFIELD WILLIAM B , MARSHALL WINSTON S
IPC分类号： A61K31/03 , C07C17/00 , C07C45/00 , C07C45/46 , C07C49/782 , C07C49/813 , A61K31/38
CPC分类号： C07C17/18 , A61K31/03 , C07C17/25 , C07C45/004 , C07C45/46 , C07C49/782 , C07C49/813 , C07C25/24
摘要： A method of treating vascular thrombosis in warmblooded animals, employing an arylacetylene as the active antithrombotic agent.
摘要翻译：一种在温血动物中治疗血管性血栓形成的方法，其中使用芳基乙炔作为活性抗血栓形成剂。

3. 发明授权

US3928571A Ruminant feed utilization improvement 失效
标题翻译：反刍动物饲料利用率的提高
公开(公告)号：US3928571A
公开(公告)日：1975-12-23
申请号：US44254174
申请日：1974-02-14
申请人： LILLY CO ELI
发明人： RAUN ARTHUR P
IPC分类号： A23K20/195 , A61K35/70
CPC分类号： A23K20/195
摘要： Ruminant animals having a developed rumen function and animals which ferment fibrous vegetable matter in the cecum convert their feed more efficiently to energy when orally treated with an antibiotic chosen from among A477, A-4696, vancomycin, and ristocetin and their physiologically-acceptable salts and esters.
摘要翻译：具有发育的瘤胃功能的反刍动物和在盲肠中发酵纤维性植物物质的动物将它们的饲料更有效地转化为能量，当用选自A477，A-4696，万古霉素和瑞斯他汀的抗生素及其生理学上可接受的盐进行口服治疗时，酯类。

4. 发明授权

US3920696A 2s-carboxyalkylthio-3r-imidoazetidin-4-ones and compounds useful in their preparation 失效
标题翻译： 2S-羧基甲基-L-咪唑并[4-ON]和其制备中有用的化合物
公开(公告)号：US3920696A
公开(公告)日：1975-11-18
申请号：US34727673
申请日：1973-04-02
申请人： LILLY CO ELI
发明人： KUKOLJA STJEPAN P , LAMMERT STEVEN R
IPC分类号： C07D403/04 , C07D205/08 , C07D209/48
CPC分类号： C07D403/04
摘要： 2S-Carboxyalkylthio-3R-imidoazetidin-4-ones can be prepared by the sequential conversion of 2-halo-1(1''-(protected)carboxy-2''methylprop-1''-enyl)-3R-imidoazetidin-4-ones to 2-halo-1(protected)carboxyoxalyl-3R-imidoazetidin-4-ones, which are converted to 2-halo-3R-imidoazetidin-4-ones, which are converted to 2S-(protected)carboxyalkylthio-3R-imidoazetidin-4-ones, which are converted to the title compounds. The title compounds exhibit antibacterial activity.

5. 发明授权

US3918913A Sampler-injector for liquid chromatography 失效
标题翻译：液相色谱采样器
公开(公告)号：US3918913A
公开(公告)日：1975-11-11
申请号：US52860774
申请日：1974-12-02
申请人： LILLY CO ELI
发明人： STEVENSON CHARLES E , COFFEY HENRY F
IPC分类号： G01N35/10 , G01N1/00 , G01N30/24 , G01N1/14
CPC分类号： G01N35/1097 , G01N30/24 , Y10T436/11
摘要： An automatic sampler-injector for use in liquid chromatographic analytical procedures is described which comprises in combination, A: (1) a cylinder closed on one end, and (2) a stopper for said cylinder, said stopper having an outside diameter slightly greater than the inside diameter of said cylinder and adapted for insertion in the open end thereof; and B: (1) a means for positioning said cylinder with said stopper in place therein beneath the point of a hollow needle, (2) an annular collar disposed around said needle at a sufficient distance from the point thereof to permit said point to penetrate said stopper, said collar having an outside diameter less than the inside diameter of said cylinder, (3) means for reciprocally moving said needle down and up in a vertical plane, (4) a conduit leading from said needle to a multiple inlet port valving means having a core with passageways communicating with said ports, (5) a closed sampling loop connected to two ports of said valving means, (6) means adapted to automatically position said valving means so that said sampling loop can first receive a sample for injection into a liquid chromatographic column and second to discharge such a sample into said chromatograph, and (7) means to effect the discharge of the contents of said sampling loop into said liquid chromatographic column.
摘要翻译：描述了一种用于液相色谱分析程序的自动进样器 - 注射器，其组合包括：（1）一端闭合的气缸，和（2）用于所述气缸的止动器，所述止动件的外径略大于所述气缸的内径适于在其开口端插入; 和B：（1）一种用于将所述气缸与所述止动器定位在中空针的点下方的装置，（2）围绕所述针头设置的环形套圈，距离其点足够的距离，以允许所述点穿透所述止动件，所述轴环的外径小于所述气缸的内径，（3）用于使所述针在垂直平面中往复运动的装置，（4）从所述针导向多个入口阀门的导管具有通道与所述端口连通的芯的装置，（5）连接到所述阀装置的两个端口的闭合采样回路，（6）适于自动定位所述阀装置的装置，使得所述采样回路可以首先接收用于注入的样品进入液相色谱柱，其次将这样的样品排放到所述色谱仪中，和（7）意味着将所述取样环的内容物排放到所述液相色谱柱中。

6. 发明授权

US3909235A Substituted sulfanilyl sulfilimine compounds as herbicides 失效
标题翻译：取代的磺胺基亚硫酰亚胺化合物作为除草剂
公开(公告)号：US3909235A
公开(公告)日：1975-09-30
申请号：US37903573
申请日：1973-07-13
申请人： LILLY CO ELI
发明人： BECK JAMES R
IPC分类号： C07D333/46 , A01N9/12
CPC分类号： C07D333/46
摘要： The present invention is directed to novel compounds of the formula

which compounds are useful as herbicides. In the above and succeeding formulae herein, R1 represents hydrogen or R2, and each R2 independently represents loweralkyl of C1-C4, loweralkenyl of C3-C4, loweralkynyl of C3-C4, or radical of the formula -CH2-CH2-CH2-nY wherein n represents 0 or 1, and Y represents methoxy, cyano, bromo, or chloro, subject to the limitation that the groups represented by R1 and R2 together contain from 2 to 8, both inclusive, carbon atoms; and each R3 is taken separately and independently represents loweralkyl of C1-C3 or phenyl, subject to the limitation that both R3 groups together, do not contain more than 8 carbon atoms, or both R3 groups are taken together, and represent a divalent radical selected from the group consisting of -CH2-2-0 -CH2-2 and -CH2-q wherein q represents 4, 5, or 6.
摘要翻译：本发明涉及式NO2 | R1R3 ANGLEN-SO2-N = S ANGLE R2R3 | NO2的新化合物，该化合物可用作除草剂。在上述和后面的公式中，R 1表示氢或R 2，每个R 2独立地表示C 1 -C 4的低级烷基，C 3 -C 4的低级链烯基，C 3 -C 4的低级炔基或式-CH 2 -CH 2 -CH 2 -YY的基团其中n表示0或1，Y表示甲氧基，氰基，溴或氯，但受限于由R1和R2表示的基团一起含有2至8个碳原子; 并且每个R 3独立地并且独立地代表C 1 -C 3或苯基的低级烷基，但受限于两个R 3基团一起不包含多于8个碳原子，或两个R 3基团一起并且表示选自二价基团由-CH2-2-0 -CH2-2和-CH2-q组成的组，其中q表示4,5或6。

7. 发明授权

US3907988A Antibiotic complex A 21101 and process for producing same 失效
标题翻译：抗生素复合物A 21101及其生产方法
公开(公告)号：US3907988A
公开(公告)日：1975-09-23
申请号：US31805672
申请日：1972-12-26
申请人： LILLY CO ELI
发明人： DELONG DONALD C , LIVELY DAVID H , NEUSS NORBERT
IPC分类号： C07D491/22 , C07G11/00 , A61K35/00
CPC分类号： C07D491/22 , C07G11/00 , Y10S435/911
摘要： Antibiotic complex comprising at least four factors produced by the cultivation of Arachniotus aureus.
摘要翻译：包含由Arachniotus aureus培养产生的至少四种因素的抗生素复合物。

8. 发明授权

US3906085A Determination of hypertension associated with elevated renin levels 失效
标题翻译：测定与肾素水平升高相关的高血压
公开(公告)号：US3906085A
公开(公告)日：1975-09-16
申请号：US52967574
申请日：1974-12-04
申请人： LILLY CO ELI
发明人： MILLER RICHARD P
IPC分类号： A61B5/021 , A61K38/57 , C12Q1/34 , A61B5/02 , A61K29/00 , A61K37/48
CPC分类号： A61K38/57 , A61B5/021 , C12Q1/34 , G01N2333/8142 , G01N2333/96472 , Y10S530/86
摘要： Method of inhibiting the action of renin by pepstatin both in vivo and in vitro, useful in determining presence of reninassociated hypertension.
摘要翻译：抑制胃蛋白酶抑制剂在体内和体外的作用的方法，可用于确定肾素相关性高血压的存在。

9. 发明授权

US3905987A M-dioxane-5-methylamine analgesics 失效
标题翻译： M-二恶烷-5-甲胺镇痛药
公开(公告)号：US3905987A
公开(公告)日：1975-09-16
申请号：US42794473
申请日：1973-12-26
申请人： LILLY CO ELI
发明人： BOOHER RICHARD N
IPC分类号： C07D213/38 , C07D213/55 , C07D319/06 , C07D213/46 , C07D319/04
CPC分类号： C07D213/38 , C07D213/55 , C07D319/06
摘要： Certain m-dioxane-5-methylamines are useful analgesic agents and intermediate 2-substituted-1,3-propanediols are useful in the preparation of such compounds.
摘要翻译：某些间二氧杂环己烷-5-甲胺是有用的止痛剂，中间体2-取代-1,3-丙二醇可用于制备这些化合物。

10. 发明授权

US3904618A 7-substituted cephalosporin compounds 失效
标题翻译： 7-取代的CEPHOROSPORIN化合物
公开(公告)号：US3904618A
公开(公告)日：1975-09-09
申请号：US42794973
申请日：1973-12-26
申请人： LILLY CO ELI
发明人： PIOCH RICHARD P
IPC分类号： A61K31/545 , C07D501/20 , C07D501/34
CPC分类号： C07D501/20
摘要： A new class of cephalosporin compounds having benzopyran, benzothiopyran, and derivatives thereof, in the side chain portion of the cephalosporin molecule.

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