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91. 发明授权

US07839967B2 Electron computer tomography method and electron computer tomograph 失效
标题翻译：电子计算机断层扫描法和电子计算机断层扫描仪
公开(公告)号：US07839967B2
公开(公告)日：2010-11-23
申请号：US11721165
申请日：2005-12-08
申请人： Michael Grass , Thomas Koehler
发明人： Michael Grass , Thomas Koehler
IPC分类号： G01N23/00
CPC分类号： G01N23/046 , A61B6/027 , A61B6/032 , A61B6/4028 , A61B6/4488 , G01N2223/419
摘要： There is provided an electron computer tomography method for recording a moving object (27), in which an electron beam is deflected onto an anode arc (14) in order to generate X-ray radiation which passes through an object (27) and is picked up by a detector device (28), wherein the X-ray radiation leaves the anode arc (14) in the form of a fan-shaped beam having a source trajectory (40) in the form of a circle segment around the object (27) and the starting point (41) of the source trajectory (40) can be changed. Also provided is an electron computer tomograph for recording a moving object (27), comprising an electron gun (8), a focusing coil (12), a curvature coil (16), an anode arc (14) for generating an X-ray beam by being struck by an electron beam of the electron gun (8), and a detector device (28) for detecting the X-ray radiation transmitted through a volume (26), said X-ray radiation having a source trajectory (40) in the form of a circle segment at the anode arc (14) and a variable starting point (41) of the source trajectory (40).
摘要翻译：提供了一种用于记录运动物体（27）的电子计算机断层摄影方法，其中电子束偏转到阳极弧（14）上，以便产生穿过物体（27）并被拾取的X射线辐射（28），其中X射线辐射以具有围绕物体（27）的圆弧形式的源轨迹（40）的扇形梁的形式离开阳极弧（14））和源轨迹（40）的起点（41）可以改变。还提供了一种用于记录运动物体（27）的电子计算机断层摄影机，包括电子枪（8），聚焦线圈（12），曲率线圈（16），用于产生X射线的阳极弧通过被电子枪（8）的电子束撞击的光束;以及用于检测透过体积（26）的X射线辐射的检测器装置（28），所述X射线辐射具有源轨迹（40）在阳极弧（14）处的圆形段和源轨迹（40）的可变起点（41）的形式。

92. 发明授权

US07778383B2 Effective dual-energy x-ray attenuation measurement 失效
标题翻译：有效的双能X射线衰减测量
公开(公告)号：US07778383B2
公开(公告)日：2010-08-17
申请号：US12293564
申请日：2007-03-14
申请人： Thomas Koehler , Jens-Peter Schlomka
发明人： Thomas Koehler , Jens-Peter Schlomka
IPC分类号： A61B6/00
CPC分类号： G01T1/2985 , A61B6/032 , A61B6/037 , A61B6/4021 , A61B6/4028 , A61B6/482 , G01V5/0041 , G01V5/005 , Y10S378/901
摘要： It is described a method and a CT system for measuring dual-energy X- ray attenuation data of an object. The CT system comprises a rotatable holder, an X-ray source comprising two different X-ray focus points, and an X-ray detection device comprising a plurality of detector elements exhibiting different spectral sensitivities. The method comprises the steps of (a) adjusting the X-ray source such that it emits X-rays originating a first focus point, (b) acquiring first attenuation data separately with first detector elements and with second detector elements, (c) moving the X-ray focus discretely to a second focus point, and (d) acquiring second attenuation data separately with both types of detector elements. Thereby the two focus points are spatially separated from each such that a first beam path originating from the first focus point penetrates a certain voxel within the object and impinges on a first detector element and a second beam path originating from the second X-ray focus point penetrates the same voxel and impinges on a second detector element.
摘要翻译：描述了用于测量物体的双能X射线衰减数据的方法和CT系统。 CT系统包括可旋转保持器，包括两个不同X射线焦点的X射线源和包括表现出不同光谱灵敏度的多个检测器元件的X射线检测装置。该方法包括以下步骤：（a）调整X射线源，使其发射源自第一焦点的X射线，（b）分别用第一检测器元件和第二检测器元件获取第一衰减数据，（c）移动所述X射线焦点离散地到达第二焦点，以及（d）分别用两种类型的检测器元件获取第二衰减数据。从而两个聚焦点在空间上分离开，使得源自第一聚焦点的第一光束路径穿透物体内的某个体素并撞击在第一X射线焦点上的第一检测器元件和第二光束路径穿透相同的体素并撞击在第二检测器元件上。

93. 发明申请

US20100166139A1 EFFECTIVE DUAL-ENERGY X-RAY ATTENUATION MEASUREMENT 失效
标题翻译：有效的双能量X射线衰减测量
公开(公告)号：US20100166139A1
公开(公告)日：2010-07-01
申请号：US12293564
申请日：2007-03-14
申请人： Thomas Koehler , Jens-Peter Schlomka
发明人： Thomas Koehler , Jens-Peter Schlomka
IPC分类号： H05G1/60 , G01T1/29
CPC分类号： G01T1/2985 , A61B6/032 , A61B6/037 , A61B6/4021 , A61B6/4028 , A61B6/482 , G01V5/0041 , G01V5/005 , Y10S378/901
摘要： It is described a method and a CT system for measuring dual-energy X- ray attenuation data of an object. The CT system comprises a rotatable holder, an X-ray source comprising two different X-ray focus points, and an X-ray detection device comprising a plurality of detector elements exhibiting different spectral sensitivities. The method comprises the steps of (a) adjusting the X-ray source such that it emits X-rays originating a first focus point, (b) acquiring first attenuation data separately with first detector elements and with second detector elements, (c) moving the X-ray focus discretely to a second focus point, and (d) acquiring second attenuation data separately with both types of detector elements. Thereby the two focus points are spatially separated from each such that a first beam path originating from the first focus point penetrates a certain voxel within the object and impinges on a first detector element and a second beam path originating from the second X-ray focus point penetrates the same voxel and impinges on a second detector element.
摘要翻译：描述了用于测量物体的双能X射线衰减数据的方法和CT系统。 CT系统包括可旋转保持器，包括两个不同X射线焦点的X射线源和包括表现出不同光谱灵敏度的多个检测器元件的X射线检测装置。该方法包括以下步骤：（a）调整X射线源，使其发射源自第一焦点的X射线，（b）分别用第一检测器元件和第二检测器元件获取第一衰减数据，（c）移动所述X射线焦点离散地到达第二焦点，以及（d）分别用两种类型的检测器元件获取第二衰减数据。从而两个聚焦点在空间上分离开，使得源自第一聚焦点的第一光束路径穿透物体内的某个体素并撞击在第一X射线焦点上的第一检测器元件和第二光束路径穿透相同的体素并撞击在第二检测器元件上。

94. 发明申请

US20090326382A1 OPTICAL IMAGING SYSTEM AND METHOD 有权
标题翻译：光学成像系统和方法
公开(公告)号：US20090326382A1
公开(公告)日：2009-12-31
申请号：US12307777
申请日：2007-06-25
申请人： Tim Nielsen , Thomas Koehler
发明人： Tim Nielsen , Thomas Koehler
IPC分类号： A61B6/00
CPC分类号： A61B5/4312 , A61B5/0091
摘要： A device for determining a concentration-related quantity of a fluorescent contrast agent applied to an object (2), in particular a turbid medium. Said device generally comprises a source (4) of electromagnetic radiation for irradiating the object (2) at an excitation wavelength and at least one first detecting means (6, 7.1, 7.2, . . . , 8) for detecting fluorescent electromagnetic radiation emitted by the contrast agent at a fluorescence wavelength, said first detecting means producing fluorescence intensity data (F). The proposed device further comprises at least one second detecting means (6, 7.1, 7.2, . . . ) for detecting electromagnetic radiation transmitted by the object (2) at the excitation wavelength, said second detecting means producing transmission intensity data (T), and evaluating means (10) adapted to receive the transmission intensity data and the fluorescence intensity data and to determine said concentration-related quantity of the contrast agent from a ratio (R) of fluorescence intensity data and transmission intensity data.
摘要翻译：一种用于确定应用于物体（2）的荧光对比剂的浓度相关量的装置，特别是混浊介质。所述装置通常包括用于以激发波长照射物体（2）的电磁辐射源（4）和至少一个第一检测装置（6,7.1,7.2，...，8），用于检测由所述造影剂处于荧光波长，所述第一检测装置产生荧光强度数据（F）。所提出的装置还包括用于检测由激光波长发射的物体（2）的电磁辐射的至少一个第二检测装置（6,7.1,7.2 ...），所述第二检测装置产生发射强度数据（T）以及评估装置（10），其适于从荧光强度数据和透射强度数据的比率（R）接收透射强度数据和荧光强度数据并确定造影剂的浓度相关量。

95. 发明申请

US20090310737A1 METHOD FOR COMPUTER TOMOGRAPHY, AND COMPUTER TOMOGRAPH 审中-公开
标题翻译：计算机图形学和计算机图形学的方法
公开(公告)号：US20090310737A1
公开(公告)日：2009-12-17
申请号：US11721543
申请日：2005-12-13
申请人： Peter Forthmann , Thomas Koehler , Robert Manzke , Michael Grass , Andy Ziegler
发明人： Peter Forthmann , Thomas Koehler , Robert Manzke , Michael Grass , Andy Ziegler
IPC分类号： A61B6/00
CPC分类号： A61B6/541 , A61B6/027 , A61B6/032 , A61B6/4085 , A61B6/503
摘要： According to the invention, there is provided a method of recording images of the heart in computer tomography, in which, in order to prevent movement artifacts, the images are reconstructed on the basis of similar movement states of the heart and different radiation intensities are used for different movement states. Also provided is a computer tomograph for recording images of the heart in computer tomography by means of time windows which exhibit similar movement states of the heart in order to prevent movement artifacts, said computer tomograph comprising a control device which controls a radiation source with different radiation intensities for different movement states. Furthermore provided is a computer program for a computer tomograph for recording images of the heart in computer tomography by means of time windows which exhibit similar movement states of the heart in order to prevent movement artifacts, and for controlling a radiation source with different radiation intensities for different movement states.
摘要翻译：根据本发明，提供了一种在计算机断层摄影中记录心脏图像的方法，其中为了防止运动伪像，基于心脏的相似运动状态重建图像，并且使用不同的辐射强度对于不同的运动状态。还提供了一种用于在计算机断层摄影中记录心脏图像的计算机断层摄影装置，其通过显示相似的心脏运动状态以防止运动伪像的时间窗口，所述计算机断层摄影机包括控制具有不同辐射的辐射源的控制装置不同运动状态的强度。此外还提供了一种计算机断层摄影机的计算机程序，用于通过时间窗口在计算机断层摄影中记录心脏的图像，所述时间窗口表现出相似的心脏运动状态以便防止运动伪像，并且用于控制具有不同辐射强度的辐射源不同的运动状态。

96. 发明申请

US20090228667A1 Performing a Least Recently Used (LRU) Algorithm for a Co-Processor 失效
标题翻译：执行协处理器的最近最少使用（LRU）算法
公开(公告)号：US20090228667A1
公开(公告)日：2009-09-10
申请号：US12399416
申请日：2009-03-06
申请人： Thomas Koehler , Siegmund Schlechter
发明人： Thomas Koehler , Siegmund Schlechter
IPC分类号： G06F12/12 , G06F12/08 , G06F12/00
CPC分类号： G06F12/123 , G06F12/1027
摘要： A method to perform a least recently used (LRU) algorithm for a co-processor is described, which co-processor in order to directly use instructions of a core processor and to directly access a main storage by virtual addresses of said core processor comprises a TLB for virtual to absolute address translations plus a dedicated memory storage also including said TLB, wherein said TLB consists of at least two zones which can be assigned in a flexible manner more than one at a time. Said method to perform a LRU algorithm is characterized in that one or more zones are replaced dependent on an actual compression service call (CMPSC) instruction.
摘要翻译：描述了为协处理器执行最近最少使用（LRU）算法的方法，其中为了直接使用核心处理器的指令并且通过所述核心处理器的虚拟地址直接访问主存储器的协处理器包括用于虚拟到绝对地址转换的TLB以及还包括所述TLB的专用存储器存储器，其中所述TLB由至少两个可以以多于一个的灵活方式分配的区域组成。所述执行LRU算法的方法的特征在于，取决于实际压缩服务呼叫（CMPSC）指令来替换一个或多个区域。

97. 发明申请

US20090153850A1 OPTICAL FLUORESCENCE TOMOGRAPHY CALIBRATION 审中-公开
标题翻译：光学荧光标定校正
公开(公告)号：US20090153850A1
公开(公告)日：2009-06-18
申请号：US12304276
申请日：2007-06-13
申请人： Tim Nielsen , Thomas Koehler
发明人： Tim Nielsen , Thomas Koehler
IPC分类号： G01J1/10 , G01J1/58
CPC分类号： A61B5/4312 , A61B5/0091 , A61B2560/0233 , G01N21/278 , G01N21/4795 , G01N21/64
摘要： The invention relates to a device for imaging an interior of a turbid medium and a medical image acquisition device comprising: a) a measurement volume (15) for accommodating the turbid medium (45); b) a light source (5) for irradiating the turbid medium (45); c) a photodetector unit 10 for detecting light emanating from the measurement volume (15). The device for imaging an interior of the turbid medium and the medical image acquisition device are adapted such that the devices further comprise a calibration device (55, 60) arranged to be optically coupled to the measurement volume (15) and comprising a calibration light source (65) arranged to simultaneously generate the excitation light and further light corresponding to the fluorescence light. The invention also relates to a calibration device (60) arranged to be inserted into a receptacle (20) that comprises a measurement volume (15) for receiving a turbid medium (45) in a device for imaging an interior of a turbid medium (45), having a contact part (70) comprising a contact surface (75) that fits at least a part of the surface of the receptacle (20) facing the measurement volume (15), and having a calibration light source (65) arranged to simultaneously generate light that causes fluorescent emission in a fluorescent agent present in the turbid medium and further light corresponding to the fluorescence light. The contact part (70) may be removable.
摘要翻译：本发明涉及一种用于对浑浊介质内部进行成像的装置和医用图像采集装置，包括：a）用于容纳混浊介质的测量体积（15）; b）用于照射混浊介质（45）的光源（5）; c）用于检测从测量体积（15）发出的光的光电检测器单元10。用于对浑浊介质和医学图像采集装置的内部进行成像的装置适于使得装置还包括校准装置（55,60），该校准装置被布置成光学耦合到测量体积（15），并且包括校准光源（65），其被布置成同时产生对应于所述荧光的激发光和另外的光。本发明还涉及一种被布置成插入到容器（20）中的校准装置（60），该容器包括用于在混浊介质（45）的内部成像的装置中接收混浊介质（45）的测量体积），其具有接触部分（70），所述接触部分（70）包括接合表面（75），所述接触表面（75）适合面向所述测量体积（15）的所述容器（20）的表面的至少一部分，并且具有校准光源（65）同时产生在混浊介质中存在的荧光剂中引起荧光发射的光，并且产生对应于荧光的另外的光。接触部分（70）可以是可移除的。

98. 发明授权

US07514518B2 Process for continuously preparing low-alkoxy silicone resins 失效
标题翻译：连续制备低烷氧基硅氧烷树脂的方法
公开(公告)号：US07514518B2
公开(公告)日：2009-04-07
申请号：US11333713
申请日：2006-01-17
申请人： Wolfgang Schattenmann , Georg Loher , Thomas Koehler
发明人： Wolfgang Schattenmann , Georg Loher , Thomas Koehler
IPC分类号： C08G77/06 , C08G77/24 , C08G77/00
CPC分类号： C08G77/06 , C08G77/18 , C08G77/34
摘要： The present invention relates to a process for preparing organopolysiloxanes by reacting halosilane with alcohol and water in the presence of the desired organopolysiloxane in a reaction unit comprising a distillation column, optionally a reflux condenser, and a vessel already containing desired organopolysiloxane, by heating the vessel contents to boiling under reflux, introducing halosilane into the column above the lower column end, removing hydrogen halide from the distillation column and continuously removing organopolysiloxane from the vessel at the same rate in which it is formed, by constantly adding halosilane, alcohol and water to the reaction unit in such amounts that more water is always present in the reaction unit than is consumed by the added Si-halogen units of the halosilanes.
摘要翻译：本发明涉及一种通过使卤代硅烷与醇和水在所需的有机聚硅氧烷存在下反应来制备有机聚硅氧烷的方法，反应单元包括蒸馏塔，任选的回流冷凝器和已经含有所需的有机聚硅氧烷的容器，通过加热容器内容物在回流下沸腾，将卤代硅烷引入下段末端的塔中，从蒸馏塔中除去卤化氢，并以与其形成的相同速率从容器中连续除去有机聚硅氧烷，通过不断加入卤代硅烷，醇和水反应单元的量使得反应单元中总是存在比卤代硅烷的加入的Si-卤素单元消耗更多的水。

99. 发明申请

US20080019473A1 Computer Tomography Method and Computer Tomograph 审中-公开
标题翻译：计算机断层扫描法和计算机断层图
公开(公告)号：US20080019473A1
公开(公告)日：2008-01-24
申请号：US11720107
申请日：2005-11-17
申请人： Thomas Koehler
发明人： Thomas Koehler
IPC分类号： G01N23/00
CPC分类号： A61B6/583
摘要： The invention describes a computer tomography method, in which a provided marker is reconstructed in order to determine the image resolution during the image reconstruction. The invention furthermore discloses a computer tomograph comprising a patient table for supporting a patient in order to expose said patient to X-ray radiation, wherein at least one marker for determining the image resolution during the image reconstruction is arranged on the patient table.
摘要翻译：本发明描述了一种计算机断层摄影方法，其中重建所提供的标记以便在图像重建期间确定图像分辨率。本发明还公开了一种计算机断层摄影机，其包括用于支撑患者以便将所述患者暴露于X射线辐射的患者台，其中用于在图像重建期间确定图像分辨率的至少一个标记被布置在患者台上。

100. 发明申请

US20070248253A1 Artifact Reduction 有权
标题翻译：人工减少
公开(公告)号：US20070248253A1
公开(公告)日：2007-10-25
申请号：US11570512
申请日：2005-06-14
申请人： Robert Manzke , Michael Grass , Thomas Koehler
发明人： Robert Manzke , Michael Grass , Thomas Koehler
IPC分类号： G06T11/00
CPC分类号： G06T11/005 , G06T2211/412
摘要： Minimizing the temporal width of the gating window during calculation of the gating function in cardiac CT may not result in best image quality with a maximum of signal-to-noise ratio and minimal artifacts. According to an exemplary embodiment of the present invention, the widths of the gating windows in cardiac CT are selected on the basis of a motion model describing the motion of the heart. According to an aspect of the present invention, the widths of the gating windows are determined by considering the duration of stationary cardiac phases. Thus, artifacts, such as motion artifacts or noise, are minimized.
摘要翻译：在计算心脏CT中门控功能时，最小化选通窗口的时间宽度可能无法以最大的信噪比和最小的人为因素产生最佳图像质量。根据本发明的示例性实施例，基于描述心脏运动的运动模型来选择心脏CT中门控窗口的宽度。根据本发明的一个方面，门控窗口的宽度通过考虑静止心脏相位的持续时间来确定。因此，最小化诸如运动伪像或噪声的伪影。

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