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11. 发明申请

US20170020551A1 MINIMALLY INVASIVE METHOD TO IMPLANT A SUBCUTANEOUS ELECTRODE 审中-公开
标题翻译：微小的入侵方法来植入一个不足的电极
公开(公告)号：US20170020551A1
公开(公告)日：2017-01-26
申请号：US15208707
申请日：2016-07-13
申请人： CAMERON HEALTH INC
发明人： G. Shantanu Reddy , Bruce A. Tockman
IPC分类号： A61B17/32 , A61B17/00 , A61B17/02 , A61N1/05
CPC分类号： A61B17/00234 , A61B17/0218 , A61B17/3201 , A61B17/32053 , A61B17/3468 , A61B2017/003 , A61B2017/0212 , A61B2017/320044 , A61B2017/320056 , A61B2017/3454 , A61N1/0504 , A61N1/3956
摘要： Methods and tool kits for implanting a lead subcutaneously. Examples include tool kits and methods for establishing first and second subcutaneous tunnels at an angle relative to one another to facilitate introduction of a lead to the subcutaneous space. In an example, a first insertion tool is used to establish a first subcutaneous tunnel, and a second insertion tool, with or without the use of a blunt dissector, sheath, guidewire, or steering mechanism, is used to initiate or form the second subcutaneous tunnel. Such methods and tool kits may reduce the number of incisions needed to implant a subcutaneous lead along a subcutaneous path having a curve therein.
摘要翻译：皮下注射铅的方法和工具包。实例包括用于以相对于彼此成一定角度建立第一和第二皮下隧道的工具包和方法，以便于将引线引入皮下空间。在一个示例中，第一插入工具用于建立第一皮下隧道，并且使用或不使用钝性解剖器，护套，导丝或转向机构的第二插入工具用于启动或形成第二皮下隧道。这样的方法和工具包可以减少沿着其中具有曲线的皮下路径植入皮下引线所需的切口数量。

12. 发明申请

US20160367829A1 CARDIAC RATE TRACKING IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可移植医疗设备中的心脏率跟踪
公开(公告)号：US20160367829A1
公开(公告)日：2016-12-22
申请号：US15254883
申请日：2016-09-01
申请人： CAMERON HEALTH, INC.
发明人： Krzysztof Z. Siejko
IPC分类号： A61N1/39
CPC分类号： A61B5/04012 , A61B5/0245 , A61B5/04011 , A61B5/04014 , A61B5/0422 , A61B5/04525 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/4836 , A61B5/686 , A61B5/7246 , A61N1/3704 , A61N1/3925 , A61N1/3956 , A61N1/3987 , G06F17/11 , G06F17/16 , G06F19/3418 , G16H10/60 , G16H40/67
摘要： Self-correlation enhancements and implementations are described. In particular, certain examples demonstrate the use of a tracking mechanism to identify and/or confirm cardiac rate using data from iterative self-correlation performed at intervals over time. This may enable the interpolation of cardiac rate in an implantable medical device when data is insufficient, and may provide confidence in cardiac rate analyses.
摘要翻译：描述了自相关增强和实现。特别地，某些实施例证明使用跟踪机制来使用随时间间隔执行的来自迭代自相关的数据来识别和/或确认心率。当数据不足时，这可以使得在可植入医疗装置中插入心率，并且可以提供对心率分析的置信度。

13. 发明授权

US09451892B2 Cardiac rate tracking in an implantable medical device 有权
标题翻译：可植入医疗器械中的心率跟踪
公开(公告)号：US09451892B2
公开(公告)日：2016-09-27
申请号：US14819817
申请日：2015-08-06
申请人： CAMERON HEALTH, INC.
发明人： Krzysztof Z. Siejko
IPC分类号： A61B5/0456 , A61B5/04 , A61N1/39 , A61B5/042 , A61B5/00 , A61B5/0452 , G06F17/16 , A61N1/37 , A61B5/0245 , A61B5/046 , A61B5/0464
CPC分类号： A61B5/04012 , A61B5/0245 , A61B5/04011 , A61B5/04014 , A61B5/0422 , A61B5/04525 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/4836 , A61B5/686 , A61B5/7246 , A61N1/3704 , A61N1/3925 , A61N1/3956 , A61N1/3987 , G06F17/11 , G06F17/16 , G06F19/3418 , G16H10/60 , G16H40/67
摘要： Self-correlation enhancements and implementations are described. In particular, certain examples demonstrate the use of a tracking mechanism to identify and/or confirm cardiac rate using data from iterative self-correlation performed at intervals over time. This may enable the interpolation of cardiac rate in an implantable medical device when data is insufficient, and may provide confidence in cardiac rate analyzes.
摘要翻译：描述了自相关增强和实现。特别地，某些实施例证明使用跟踪机制来使用随时间间隔执行的来自迭代自相关的数据来识别和/或确认心率。当数据不足时，这可以使得在可植入医疗装置中插入心率，并且可以提供对心率分析的置信度。

14. 发明申请

US20160235998A1 MULTIPLE ELECTRODE VECTORS FOR IMPLANTABLE CARDIAC TREATMENT DEVICES 有权
标题翻译：用于可植入心脏治疗装置的多极电极矢量
公开(公告)号：US20160235998A1
公开(公告)日：2016-08-18
申请号：US15138674
申请日：2016-04-26
申请人： CAMERON HEALTH INC
发明人： Jay A. Warren , Gust H. Bardy
IPC分类号： A61N1/39 , A61B5/04 , A61N1/37 , A61B5/042
CPC分类号： A61N1/3925 , A61B5/04011 , A61B5/042 , A61B5/0424 , A61B5/7203 , A61B5/7207 , A61N1/3622 , A61N1/3706 , A61N1/3987
摘要： The implantable cardiac treatment system of the present invention is capable of choosing the most appropriate electrode vector to sense within a particular patient. In certain embodiments, the implantable cardiac treatment system determines the most appropriate electrode vector for continuous sensing based on which electrode vector results in the greatest signal amplitude, or some other useful metric such as signal-to-noise ratio (SNR). The electrode vector possessing the highest quality as measured using the metric is then set as the default electrode vector for sensing. Additionally, in certain embodiments of the present invention, a next alternative electrode vector is selected based on being generally orthogonal to the default electrode vector. In yet other embodiments of the present invention, the next alternative electrode vector is selected based on possessing the next highest quality metric after the default electrode vector. In some embodiments, if analysis of the default vector is ambiguous, the next alternative electrode vector is analyzed to reduce ambiguity.
摘要翻译：本发明的可植入心脏治疗系统能够选择最合适的电极载体以在特定患者体内感测。在某些实施例中，可植入心脏治疗系统基于哪个电极向量导致最大的信号幅度或诸如信噪比（SNR）的一些其他有用的度量来确定用于连续感测的最合适的电极向量。使用度量测量的具有最高质量的电极矢量然后被设置为用于感测的默认电极矢量。另外，在本发明的某些实施例中，基于大致正交于默认电极向量来选择下一个备选电极矢量。在本发明的其它实施例中，基于在默认电极向量之后拥有下一个最高质量度量来选择下一个备选电极矢量。在一些实施例中，如果默认矢量的分析是不明确的，则分析下一个替代电极矢量以减少模糊度。

15. 发明授权

US09364677B2 Systems and methods for sensing vector selection in an implantable medical device 有权
标题翻译：用于在可植入医疗装置中感测矢量选择的系统和方法
公开(公告)号：US09364677B2
公开(公告)日：2016-06-14
申请号：US14304084
申请日：2014-06-13
申请人： Cameron Health, Inc.
发明人： Rick Sanghera , Venugopal Allavatam
IPC分类号： A61N1/368 , A61B5/04 , A61B5/0452 , A61N1/37 , A61N1/372 , A61N1/39 , A61B5/00
CPC分类号： A61B5/04011 , A61B5/0031 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/686 , A61N1/368 , A61N1/3704 , A61N1/37211 , A61N1/3918 , A61N1/3956
摘要： Methods and devices for sensing vector analysis in an implantable cardiac stimulus system. In an illustrative example, a first sensing vector is analyzed to determine whether it is suitable, within given threshold conditions, for use in cardiac event detection and analysis. If so, the first vector may be selected for detection and analysis. Otherwise, one or more additional vectors are analyzed. A detailed example illustrates methods for analyzing sensing vectors by the use of a scoring system. Devices adapted to perform these methods are also discussed, including implantable medical devices adapted to perform these methods, and systems comprising implantable medical devices and programmers adapted to communicate with implantable medical devices, the systems also being adapted to perform these methods. Another example includes a programmer configured to perform these methods including certain steps of directing operation of an associated implanted or implantable medical device.
摘要翻译：用于在可植入心脏刺激系统中感测矢量分析的方法和装置。在说明性示例中，分析第一感测向量以确定在给定阈值条件内是否适合用于心脏事件检测和分析。如果是这样，可以选择第一个载体进行检测和分析。否则，分析一个或多个附加向量。详细的例子说明了通过使用评分系统来分析感测矢量的方法。还讨论了适于执行这些方法的装置，包括适于执行这些方法的可植入医疗装置，以及包括适于与可植入医疗装置通信的可植入医疗装置和程序员的系统，该系统还适于执行这些方法。另一示例包括被配置为执行这些方法的程序员，包括指导相关联的植入式或可植入医疗设备的操作的某些步骤。

16. 发明申请

US20160045136A1 CALCULATION OF SELF-CORRELATION IN AN IMPLANTABLE CARDIAC DEVICE 有权
标题翻译：在可植入心脏装置中计算自相关
公开(公告)号：US20160045136A1
公开(公告)日：2016-02-18
申请号：US14819889
申请日：2015-08-06
申请人： CAMERON HEALTH, INC.
发明人： Krzysztof Z. Siejko , Paul Huelskamp
IPC分类号： A61B5/0452 , A61B5/042 , A61N1/39 , A61B5/04 , A61B5/00 , A61B5/0456 , G06F17/16 , A61B5/0245
CPC分类号： A61B5/04012 , A61B5/0245 , A61B5/04011 , A61B5/04014 , A61B5/0422 , A61B5/04525 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/4836 , A61B5/686 , A61B5/7246 , A61N1/3704 , A61N1/3925 , A61N1/3956 , A61N1/3987 , G06F17/11 , G06F17/16 , G06F19/3418 , G16H10/60 , G16H40/67
摘要： Self-correlation enhancements and implementations are described. In particular, certain examples demonstrate the analytical tools to reduce the computational burden of generating a self-correlation function within an implantable medical device. Peak selector and tracking analysis are also included as secondary elements for identifying and generating confidence in rate estimates based on the self-correlation function. The approach may enable an alternative calculation of cardiac rate in an implantable medical device as a stand-alone rate detector or as a double-check of other rate calculations.
摘要翻译：描述了自相关增强和实现。特别地，某些实例展示了降低在可植入医疗设备内产生自相关功能的计算负担的分析工具。峰值选择器和跟踪分析也被包括作为辅助元件，用于基于自相关函数识别和产生速率估计的置信度。该方法可以使得在可植入医疗装置中作为独立速率检测器或作为其他速率计算的双重检查来替代地计算心率。

17. 发明申请

US20150375004A1 ADAPTIVE CONFIRMATION OF TREATABLE ARRHYTHMIA IN IMPLANTABLE CARDIAC STIMULUS DEVICES 审中-公开
标题翻译：可植入性牙周炎手术中的可治疗性脑膜炎的自适应确定
公开(公告)号：US20150375004A1
公开(公告)日：2015-12-31
申请号：US14852701
申请日：2015-09-14
申请人： CAMERON HEALTH, INC.
发明人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam
IPC分类号： A61N1/39
CPC分类号： A61N1/3987 , A61B5/0464 , A61N1/3622 , A61N1/3925 , A61N1/3943 , A61N1/3956
摘要： Methods and devices for adjusting therapy delivery decisions in an implantable cardiac stimulus device by observing cardiac activity following an initial identification of a treatable condition. In some examples, cardiac activity that appears benign is quantified and a therapy confirmation threshold is adjusted according to how much apparently benign cardiac activity is seen after an initial identification of a treatable condition. In other examples, a new threshold is applied following the initial identification of treatable condition, removing historical data preceding the initial identification from subsequent therapy delivery decisions.
摘要翻译：用于通过在初始识别可治疗病症后观察心脏活动来调整可植入心脏刺激装置中的治疗递送决定的方法和装置。在一些实例中，显示良性的心脏活动被定量，并且根据在可治疗病症的初始鉴定之后看到多少明显良性的心脏活动来调整治疗确认阈值。在其他示例中，在可治疗条件的初始识别之后应用新阈值，从随后的治疗递送决定中移除初始识别之前的历史数据。

18. 发明申请

US20150251000A1 IMPLANTABLE MEDICAL DEVICE HAVING A CONDUCTIVE COATING 审中-公开
标题翻译：具有导电涂层的可植入医疗装置
公开(公告)号：US20150251000A1
公开(公告)日：2015-09-10
申请号：US14637535
申请日：2015-03-04
申请人： CAMERON HEALTH, INC.
发明人： Michael J. Kane , Matthew P. Jones , Sverre Gropen
IPC分类号： A61N1/05 , C23C14/06 , C23C14/34 , C23C14/14 , C23C16/44 , C25D13/02
CPC分类号： A61N1/0504 , A61N1/375 , A61N1/3756 , C23C14/00 , C23C14/0641 , C23C14/165 , C25D13/02
摘要： An implantable medical device including a coating and associated method are disclosed. The implantable medical device can include a metallic housing. An adhesion layer formed on at least a portion of the metallic housing. A titanium nitride base layer formed on at least a portion of the adhesion layer. An intermediate layer formed on at least a portion of the titanium nitride base layer, and a titanium nitride top layer formed on at least a portion of the intermediate layer.
摘要翻译：公开了一种包括涂层和相关方法的可植入医疗装置。可植入医疗装置可以包括金属外壳。形成在金属外壳的至少一部分上的粘附层。形成在粘合层的至少一部分上的氮化钛基层。形成在氮化钛基层的至少一部分上的中间层和形成在中间层的至少一部分上的氮化钛顶层。

19. 发明申请

US20150182171A1 SENSING VECTOR SELECTION IN A CARDIAC STIMULUS DEVICE WITH POSTURAL ASSESSMENT 审中-公开
标题翻译：感觉矢量选择在具有后期评估的心脏刺激装置中
公开(公告)号：US20150182171A1
公开(公告)日：2015-07-02
申请号：US14601315
申请日：2015-01-21
申请人： CAMERON HEALTH, INC.
发明人： Rick Sanghera , Venugopal Allavatam
IPC分类号： A61B5/00 , A61B5/04 , A61N1/39
CPC分类号： A61N1/37247 , A61B5/04011 , A61B5/042 , A61B5/1116 , A61B5/7221 , A61N1/36535 , A61N1/368 , A61N1/37 , A61N1/3702 , A61N1/3704 , A61N1/3925 , A61N1/3956
摘要： Methods, implantable medical devices and systems configured to perform analysis of captured signals from implanted electrodes to identify cardiac arrhythmias. In an illustrative embodiment, signals captured from two or more sensing vectors are analyzed, where the signals are captured with a patient in at least first and second body positions. Analysis is performed to identify primary or default sensing vectors and/or templates for event detection.
摘要翻译：方法，植入式医疗装置和系统被配置为执行从植入电极捕获的信号的分析以识别心律失常。在说明性实施例中，分析从两个或更多个感测向量捕获的信号，其中在至少第一和第二身体位置中与患者一起捕获信号。执行分析以识别用于事件检测的主要或默认感测向量和/或模板。

20. 发明申请

US20150115900A1 SELECTABLE UPPER VOLTAGE RANGE MONITORING CIRCUIT 有权
标题翻译：可选择上电压范围监控电路
公开(公告)号：US20150115900A1
公开(公告)日：2015-04-30
申请号：US14067266
申请日：2013-10-30
申请人： Cameron Health, Inc.
发明人： Ravi S. Ananth
IPC分类号： G01R31/36 , H02J7/34
CPC分类号： G01R31/362 , A61N1/3975 , G01R15/08 , H02J7/345
摘要： A battery voltage measuring circuit for an implantable cardiac device is presented. Since the usable battery voltage for the device is limited to an upper range of voltages, the need for measuring lower voltages at which the battery is approaching end of life is of no use. The disclosed invention allows for the measurement of a selectable upper range of battery levels that can be chosen without using a level shifting device such as a zener diode. Multiple voltage ranges with associated measurement resolutions can be achieved without using high current zener diode implementations. This allows for a trade-off between measurement range and resolution while resulting in a lower power and more accurate measurement circuit. Conventional zener diode implementations only allow for a single measurement range and are prone to non-linear error as the voltage measurement range increases.
摘要翻译：提出了一种用于植入式心脏装置的电池电压测量电路。由于器件的可用电池电压被限制在较高的电压范围内，所以对电池正在接近寿命结束的较低电压进行测量的需求是没有用的。所公开的发明允许测量可以在不使用诸如齐纳二极管的电平转换装置的情况下选择的可选择的电池电平的上限范围。可以在不使用高电流齐纳二极管实现的情况下实现具有相关测量分辨率的多个电压范围。这允许在测量范围和分辨率之间进行权衡，同时导致更低的功率和更精确的测量电路。传统的齐纳二极管实现仅允许单个测量范围，并且随着电压测量范围的增加而容易发生非线性误差。

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