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11. 发明申请

US20060030833A1 Catheter with sensor tip and method of use of same 有权
标题翻译：带传感器端头的导管及其使用方法
公开(公告)号：US20060030833A1
公开(公告)日：2006-02-09
申请号：US11037154
申请日：2005-01-19
申请人： Chad Harris , Matthew Hawk , Timothy Mickley , Dorin Panescu , Maria Palasis , Jacob Rooney
发明人： Chad Harris , Matthew Hawk , Timothy Mickley , Dorin Panescu , Maria Palasis , Jacob Rooney
IPC分类号： A61M31/00 , A61B5/02
CPC分类号： A61B5/0422 , A61B5/6852 , A61B2018/00875 , A61B2018/1425 , A61B2218/002 , A61M25/0084 , A61M25/0136 , A61M2025/0096 , A61N1/0568
摘要： An apparatus and method for catheter-based sensing and injection at a target site within a patient's body. An injection catheter is equipped with electrodes at its distal end which contact the surface of a target site, such as an AV node of the heart. Electrical signals detected at the target site by the electrodes are fed via leads to the proximal end of the catheter, where they are received by a monitor, such as an EKG monitor. If the electrical signals satisfy predetermined criteria, a needle within the catheter is extended into the target site, and a therapeutic agent is injected into the target site.
摘要翻译：一种用于在患者体内的目标部位进行基于导管的感测和注射的装置和方法。注射导管在其远端配备有电极，其接触目标部位的表面，例如心脏的AV节点。通过电极在目标部位检测到的电信号通过引线馈送到导管的近端，在那里它们被诸如EKG监视器的监视器接收。如果电信号满足预定标准，则导管内的针头延伸到目标部位，并将治疗剂注射到目标部位。

12. 发明申请

US20050197657A1 Thermokeratoplasty system with a regulated power generator 审中-公开
标题翻译：具有稳压发电机的热机器人成形系统
公开(公告)号：US20050197657A1
公开(公告)日：2005-09-08
申请号：US10792152
申请日：2004-03-02
申请人： Paul Goth , William Bowers , Dorin Panescu
发明人： Paul Goth , William Bowers , Dorin Panescu
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B18/1815 , A61B2018/00678 , A61B2018/00708 , A61B2018/00791 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/1425 , A61F9/0079 , A61F2009/00872
摘要： An apparatus that provides energy to a probe in contact with a cornea to perform a medical procedure. The apparatus includes a circuit that supplies energy to the probe and a regulator that regulates the delivery of energy during the medical procedure. The apparatus may include a sensing circuit that senses a change in a physiology of the cornea. The regulator can vary the energy delivered to the cornea in accordance with changes in the cornea physiology. For example, a waveform of tissue impedance may be determined and compared to a desired waveform. Deviations from the desired waveform may cause the regulator to increase or decrease the power applied to the cornea.
摘要翻译：向与角膜接触的探针提供能量以执行医疗程序的装置。该装置包括向探针供应能量的电路和调节在医疗过程期间能量输送的调节器。该装置可以包括感测角膜生理变化的感测电路。调节器可以根据角膜生理学的变化改变传递给角膜的能量。例如，可以确定组织阻抗的波形并将其与期望的波形进行比较。与期望波形的偏差可能导致调节器增加或减少施加到角膜的功率。

13. 发明授权

US06824515B2 Ultrasound-guided ablation catheter and methods of use 有权
标题翻译：超声引导消融导管及使用方法
公开(公告)号：US06824515B2
公开(公告)日：2004-11-30
申请号：US10305256
申请日：2002-11-25
申请人： Veijo T. Suorsa , David K. Swanson , Dorin Panescu , Harm TenHoff , James G. Whayne
发明人： Veijo T. Suorsa , David K. Swanson , Dorin Panescu , Harm TenHoff , James G. Whayne
IPC分类号： A61B812
CPC分类号： A61B18/1492 , A61B2017/00106 , A61B2018/0016 , A61B2018/00351 , A61B2018/00577 , A61B2018/00654 , A61B2018/124 , A61B2090/065 , A61B2090/3784 , A61N7/02 , A61N2007/0078
摘要： The present invention provides ultrasound-guided ablation catheters and methods for their use. In one embodiment, a tissue ablation apparatus (2) includes a flexible elongate body (12) having proximal (14) and distal (12) ends. A plurality of spaced-apart electrodes (24) are operably attached to the flexible body near the distal end. A plurality of transducer elements (28) are disposed between at least some of the electrodes. Transducers assist the physician in determining whether or not the ablation elements are in contact with the tissue to be ablated.
摘要翻译：本发明提供超声引导消融导管及其使用方法。在一个实施例中，组织消融装置（2）包括具有近端（14）和远端（12）端部的柔性细长体（12）。多个间隔开的电极（24）在远端附近可操作地附接到柔性体。多个换能器元件（28）设置在至少一些电极之间。传感器帮助医师确定消融元件是否与要消融的组织接触。

14. 发明授权

US06790206B2 Compensation for power variation along patient cables 有权
标题翻译：患者电缆功率变化补偿
公开(公告)号：US06790206B2
公开(公告)日：2004-09-14
申请号：US10066054
申请日：2002-01-31
申请人： Dorin Panescu
发明人： Dorin Panescu
IPC分类号： A61B1818
CPC分类号： A61B18/1206 , A61B2018/00702 , A61B2018/00892
摘要： A method and system for delivering power over a patient cable to a therapeutic device, in which a variable that depends on the delivered power is sensed or measured near a distal end of the patient cable, and a feedback signal is generated based on the sensed or measured value. The delivered power is adjusted based at least in part on the feedback signal to compensate for power variance along the patient cable.
摘要翻译：一种用于将病人电缆上的电力输送到治疗装置的方法和系统，其中在患者电缆的远端附近感测或测量取决于所输送的功率的变量，并且基于感测或测量值。至少部分地基于反馈信号调整输送功率，以补偿患者电缆的功率变化。

15. 发明授权

US06542773B2 Interactive systems and methods for controlling the use of diagnostic or therapeutic instruments in interior body regions 有权
标题翻译：用于控制在内部身体区域使用诊断或治疗仪器的交互式系统和方法
公开(公告)号：US06542773B2
公开(公告)日：2003-04-01
申请号：US09848182
申请日：2001-05-02
申请人： Daniel A. Dupree , Tuan Nguyen , Dorin Panescu , James G. Whayne , David McGee , David K. Swanson
发明人： Daniel A. Dupree , Tuan Nguyen , Dorin Panescu , James G. Whayne , David McGee , David K. Swanson
IPC分类号： A61B50402
CPC分类号： A61B5/0422 , A61B5/0464 , A61B5/06 , A61B5/063 , A61B5/6858 , A61B5/7435 , A61B5/7445 , A61B5/7475 , A61B18/1492 , A61B2018/00214 , A61B2018/00898 , G06F19/00 , G06F19/3481 , G16H10/60 , G16H40/63
摘要： An interface is associated with a structure which, in use, is deployed in an interior body region of a patient. The structure includes an operative element coupled to a controller, which establishes an operating condition for the operative element to perform a diagnostic or therapeutic procedure in the interior body region. The interface generates a first display comprising an image of the structure at least partially while the operative element performs the procedure. The interface also generates a second display comprising one or more data fields reflecting the operating condition of the controller. The interface enables selection of the first display or the second display for viewing on a display screen.
摘要翻译：界面与在使用中部署在患者的内部身体区域中的结构相关联。该结构包括耦合到控制器的操作元件，其建立操作元件在内部身体区域中执行诊断或治疗过程的操作条件。该接口在操作元件执行该过程时至少部分地生成包括该结构的图像的第一显示器。接口还产生包括反映控制器的操作条件的一个或多个数据字段的第二显示器。该接口使得能够选择第一显示器或第二显示器以在显示屏幕上观看。

16. 发明授权

US06471699B1 Systems and methods for forming elongated lesion patterns in body tissue using straight or curvilinear electrode elements 失效
标题翻译：使用直线或曲线电极元件在身体组织中形成细长病变图案的系统和方法
公开(公告)号：US06471699B1
公开(公告)日：2002-10-29
申请号：US09579730
申请日：2000-05-26
申请人： Sidney D. Fleischman , Thomas Bourne , Dorin Panescu , David K. Swanson , James G. Whayne
发明人： Sidney D. Fleischman , Thomas Bourne , Dorin Panescu , David K. Swanson , James G. Whayne
IPC分类号： A61B1818
CPC分类号： A61B5/0422 , A61B5/6855 , A61B5/6857 , A61B5/6858 , A61B18/1402 , A61B18/1492 , A61B18/1815 , A61B2017/00084 , A61B2017/00088 , A61B2017/00092 , A61B2017/00292 , A61B2017/003 , A61B2018/00083 , A61B2018/00107 , A61B2018/00148 , A61B2018/0016 , A61B2018/00196 , A61B2018/00214 , A61B2018/00267 , A61B2018/00357 , A61B2018/00577 , A61B2018/00755 , A61B2018/00791 , A61B2018/00839 , A61B2018/00869 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1435 , A61B2018/1497 , A61B2018/1861 , A61B2562/0209 , A61B2562/043 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61M25/0041 , A61M2025/09141 , A61N1/056 , A61N1/06 , A61N1/40 , A61N1/403 , G01K1/026 , G01K3/14 , C08L1/02
摘要： Systems and associated methods position arrays of multiple emitters of ablating energy in straight or curvilinear positions in contact with tissue to form elongated lesion patterns. The elongated lesion patterns can continuous or interrupted, depending upon the orientation of the energy emitters.
摘要翻译：系统和相关方法将多个发射器的阵列放置在与组织接触的直线或曲线位置中，以形成细长的病变图案。取决于能量发射器的取向，细长的损伤图案可以连续或中断。

17. 发明授权

US06289239B1 Interactive systems and methods for controlling the use of diagnostic or therapeutic instruments in interior body regions 有权
标题翻译：用于控制在内部身体区域使用诊断或治疗仪器的交互式系统和方法
公开(公告)号：US06289239B1
公开(公告)日：2001-09-11
申请号：US09538133
申请日：2000-03-29
申请人： Dorin Panescu , David McGee , James G. Whayne , Robert R. Burnside , David K. Swanson , Daniel A. Dupree
发明人： Dorin Panescu , David McGee , James G. Whayne , Robert R. Burnside , David K. Swanson , Daniel A. Dupree
IPC分类号： A61B5044
CPC分类号： A61B5/0422 , A61B5/0464 , A61B5/06 , A61B5/063 , A61B5/6858 , A61B5/7435 , A61B5/7445 , A61B5/7475 , A61B18/1492 , A61B2018/00214 , A61B2018/00898 , G06F19/00 , G06F19/3481 , G16H10/60 , G16H40/63
摘要： An interface is associated with a structure which, in use, is deployed in an interior body region of a patient. The structure includes an operative element coupled to a controller, which establishes an operating condition for the operative element to perform a diagnostic or therapeutic procedure in the interior body region. The interface generates a first display comprising an image of the structure at least partially while the operative element performs the procedure. The interface also generates a second display comprising one or more data fields reflecting the operating condition of the controller. The interface enables selection of the first display or the second display for viewing on a display screen.
摘要翻译：界面与在使用中部署在患者的内部身体区域中的结构相关联。该结构包括耦合到控制器的操作元件，其建立操作元件在内部身体区域中执行诊断或治疗过程的操作条件。该接口在操作元件执行该过程时至少部分地生成包括该结构的图像的第一显示器。接口还产生包括反映控制器的操作条件的一个或多个数据字段的第二显示器。该接口使得能够选择第一显示器或第二显示器以在显示屏幕上观看。

18. 发明授权

US06188924B1 Systems and methods for acquiring making time-sequential measurements of biopotentials sensed in myocardial tissue 有权
标题翻译：用于获取在心肌组织中感测的生物电位的时间顺序测量的系统和方法
公开(公告)号：US06188924B1
公开(公告)日：2001-02-13
申请号：US09247442
申请日：1999-02-10
申请人： David K. Swanson , James G. Whayne , Dorin Panescu
发明人： David K. Swanson , James G. Whayne , Dorin Panescu
IPC分类号： A61B50402
CPC分类号： A61B5/6855 , A61B1/0051 , A61B5/0422 , A61B5/04525 , A61B5/6858 , A61B18/1492 , A61N1/056 , G06F19/00 , G16H15/00 , G16H40/63
摘要： Systems and methods for generating a composite signal derived from biopotentials sensed in myocardial tissue are disclosed and described. One such method includes inputting a first set of signals comprising biopotentials sensed at a first group of tissue sites during a first time interval; inputting a second set of signals comprising biopotentials sensed at a second group of tissue sites during a second time interval sequentially after the first time interval, wherein at least one of the biopotentials sensed as part of the first set of signals is not sensed as part of the second set of signals, and at least one of the biopotentials sensed as part of the second set of signals is not sensed as part of the first set of signals; and time aligning the first and second sets of signals using biopotentials sensed at the same site as part of both the first and second sets of signals, thereby generating the composite signal arranged for analysis as if all biopotentials were sensed during a common time interval, whereby the composite signal provides a diagnostic indicator.
摘要翻译：公开和描述了用于产生从心肌组织中感测的生物电位得到的复合信号的系统和方法。一种这样的方法包括在第一时间间隔期间输入包括在第一组组织位点处感测的生物电位的第一组信号; 在所述第一时间间隔之后，在第二时间间隔期间输入包括在第二组组织位置处感测的生物电位的第二组信号，其中作为所述第一组信号的一部分感测到的所述生物电位中的至少一个未被感测为所述第二组信号以及作为所述第二组信号的一部分感测到的所述生物电位中的至少一个未被感测为所述第一组信号的一部分; 以及使用在同一位点处感测的生物电位作为第一组信号和第二组信号的一部分的时间对齐第一组信号和第二组信号，从而生成布置成用于分析的复合信号，好像在公共时间间隔期间感测到所有生物电位一样，由此复合信号提供诊断指示器。

19. 发明授权

US06179835B2 Expandable-collapsible electrode structures made of electrically conductive material 失效
标题翻译：由导电材料制成的可膨胀 - 可折叠电极结构
公开(公告)号：US06179835B2
公开(公告)日：2001-01-30
申请号：US09300936
申请日：1999-04-27
申请人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
发明人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
IPC分类号： A61B1814
CPC分类号： A61N1/06 , A61B18/1492 , A61B2017/00053 , A61B2017/00243 , A61B2017/22051 , A61B2017/22061 , A61B2018/00065 , A61B2018/00083 , A61B2018/00095 , A61B2018/00107 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00839 , A61B2018/1253 , A61B2018/1472 , A61B2218/002 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , C08L1/02
摘要： Electrode assemblies and associated systems employ a nonporous wall having an exterior for contacting tissue. The exterior peripherally surrounds an interior area. The wall is essentially free of electrically conductive material. The wall is adapted to assume an expanded geometry having a first maximum diameter and a collapsed geometry having a second maximum diameter less than the first maximum diameter. The assemblies and systems include a lumen that conveys a medium containing ions into the interior area. An element free of physical contact with the wall couples the medium within the interior area to a source of electrical energy to enable ionic transport of electrical energy from the source through the medium to the wall for capacitive coupling to tissue contacting the exterior of the wall.
摘要翻译：电极组件和相关系统采用具有用于接触组织的外部的无孔壁。外部外围围绕着内部区域。该壁基本上不含导电材料。壁适于呈现具有第一最大直径和具有小于第一最大直径的第二最大直径的折叠几何形状的扩展几何形状。组件和系统包括将含有离子的介质输送到内部区域的内腔。与壁物理接触的元件将内部区域内的介质耦合到电能源，以使电能从源通过介质到壁的电能离子传输，用于电容耦合到与壁的外部接触的组织。

20. 发明授权

US6129669A Systems and methods for assessing stability of an ablation electrode in contact with heart tissue 失效
标题翻译：用于评估与心脏组织接触的消融电极的稳定性的系统和方法
公开(公告)号：US6129669A
公开(公告)日：2000-10-10
申请号：US83712
申请日：1998-05-22
申请人： Dorin Panescu , Arnold J. Greenspon
发明人： Dorin Panescu , Arnold J. Greenspon
IPC分类号： A61B5/06 , A61B19/00 , A61B5/05
CPC分类号： A61B18/1492 , A61B5/06 , A61B5/7203 , A61B34/20
摘要： Systems and methods sense stability of an ablation instrument inside a body region. The systems and methods position a tracking element in a fixed location spaced from the ablation instrument. The systems and methods generate an output, which varies according to movement of the ablation instrument relative to the tracking element over time.
摘要翻译：系统和方法检测身体区域内消融器械的稳定性。系统和方法将跟踪元件定位在与消融器具隔开的固定位置。系统和方法产生输出，其根据消融器具相对于跟踪元件随时间的移动而变化。

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