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31. 发明申请

US20190251713A1 SYSTEM AND METHOD FOR MULTI-ARCHITECTURE COMPUTED TOMOGRAPHY PIPELINE 审中-公开
公开(公告)号：US20190251713A1
公开(公告)日：2019-08-15
申请号：US16275129
申请日：2019-02-13
申请人： Wisconsin Alumni Research Foundation
发明人： Guang-Hong Chen , Yinsheng Li
IPC分类号： G06T11/00 , A61B6/00 , G06N3/08 , G06N7/00 , G06N20/20
CPC分类号： G06T11/006 , A61B6/5205 , G06N3/084 , G06N7/005 , G06N20/20 , G06T2210/41
摘要： A system and method for reconstructing an image of a subject acquired using a tomographic imaging system includes at least one computer processor configured to form an image reconstruction pipeline. The reconstruction pipeline at least includes an automated correction module configured to receive imaging data acquired from a subject using ionizing radiation generated by the tomographic imaging system and generate corrected data using a first learning network. The reconstruction pipeline also includes an intelligent reconstruction module configured to receive at least one of the imaging data and the corrected data and reconstruct an image of the subject using a second learning network.

32. 发明授权

US10147207B2 System and method for high-temporal resolution, time-resolved cone beam CT angiography 有权
公开(公告)号：US10147207B2
公开(公告)日：2018-12-04
申请号：US15211448
申请日：2016-07-15
申请人： Wisconsin Alumni Research Foundation
发明人： Guang-Hong Chen , Charles Strother
IPC分类号： G06T11/00 , A61B6/00 , A61B6/03
摘要： A system and method for reconstructing an image using a cone-beam computed tomography (CT) imaging system includes acquiring data from a subject with the CT imaging system using a limited scan range that is less than 360 degrees. The process also includes reconstructing at least one image of the subject having a first temporal resolution from the data acquired, performing a temporal deconvolution of the at least one image using a finite temporal window to generate at least one image of the subject with a second temporal resolution that is greater than the first temporal resolution, and subtracting the at least one image of the subject with the second temporal resolution and a mask image of the subject to generate a time-resolved CT angiogram of the subject.

33. 发明申请

US20180276852A1 SYSTEM AND METHOD FOR DATA-CONSISTENCY PREPARATION AND IMAGE RECONSTRUCTION 审中-公开
公开(公告)号：US20180276852A1
公开(公告)日：2018-09-27
申请号：US15467574
申请日：2017-03-23
申请人： Wisconsin Alumni Research Foundation
发明人： Guang-Hong Chen
IPC分类号： G06T11/00 , G06T7/10 , G06T7/00
CPC分类号： G01N23/046 , G01N2223/401 , G01R33/565 , G06T11/005 , G06T2211/412
摘要： A system and method for reconstructing an image of a subject includes acquiring a reference dataset and reconstructing a prior image of the subject from the reference dataset and selecting at least a portion of the prior image that corresponds to a portion of the prior image of the subject that is free of artifacts. The method also includes acquiring a medical imaging dataset of the subject, performing a vertical comparison of the medical imaging dataset and the reference dataset to create a data inconsistency metric, and repeating the preceding steps to create a plurality of data inconsistency metrics. The method further includes performing a horizontal comparison of the data inconsistency metrics to identify inconsistent data, compensating for the inconsistent data, and reconstructing an image of the subject with reduced artifacts compared to the prior image.

34. 发明授权

US09384566B2 System and method for simulataneous image artifact reduction and tomographic reconstruction 有权
标题翻译：用于模拟图像伪像减少和断层重建的系统和方法
公开(公告)号：US09384566B2
公开(公告)日：2016-07-05
申请号：US13828103
申请日：2013-03-14
申请人： Wisconsin Alumni Research Foundation
发明人： Guang-Hong Chen
IPC分类号： G06K9/00 , G06T11/00
CPC分类号： G06T11/003 , G06T11/006 , G06T2211/412 , G06T2211/424
摘要： Described here is a system and method for image reconstruction that can automatically and iteratively produce multiple images from one set of acquired data, in which each of these multiple images corresponds to a subset of the acquired data that is self-consistent, but inconsistent with other subsets of the acquired data. The image reconstruction includes iteratively minimizing the rank of an image matrix whose columns each correspond to a different image. The rank minimization is constrained subject to a consistency condition that enforces consistency between the forward projection of each column in the image matrix and a respective subset of the acquired data that contains data that is consistent with data in the subset, but inconsistent with data not in the subset.
摘要翻译：这里描述了一种用于图像重构的系统和方法，其可以从一组采集的数据自动和迭代地产生多个图像，其中这些多个图像中的每一个对应于所获取的数据的子集，其是自相矛盾的，但与其他的不一致获取的数据的子集。图像重建包括迭代地最小化其列各自对应于不同图像的图像矩阵的等级。排序最小化受制于一致性条件，强制图像矩阵中每列的前向投影与包含与该子集中的数据一致的数据的所获取数据的相应子集之间的一致性一致，但与不在子集。

35. 发明授权

US09208588B2 Fast statistical imaging reconstruction via denoised ordered-subset statistically-penalized algebraic reconstruction technique 有权
标题翻译：通过去噪有序子集统计学惩罚的代数重建技术快速统计成像重建
公开(公告)号：US09208588B2
公开(公告)日：2015-12-08
申请号：US14036599
申请日：2013-09-25
申请人： Wisconsin Alumni Research Foundation
发明人： Guang-Hong Chen , Jie Tang
IPC分类号： G06T11/00 , G06T5/00
CPC分类号： G06T11/008 , G06T5/002 , G06T11/006 , G06T2211/424 , G06T2211/428
摘要： Described here are systems and methods for iteratively reconstructing images from data acquired using a medical imaging system. The image reconstruction is decomposed into separate linear sub-problems that can be more efficiently solved. A statistical image reconstruction process is decomposed into a statistically-weighted algebraic reconstruction update sequence. After this step, the reconstructed image is denoised using a regularization function.
摘要翻译：这里描述了用于从使用医学成像系统获取的数据迭代重建图像的系统和方法。图像重建被分解成可以更有效地解决的单独的线性子问题。统计图像重建过程被分解为统计加权代数重构更新序列。在该步骤之后，使用正则化函数对重建的图像进行去噪。

36. 发明授权

US09076237B2 System and method for estimating a statistical noise map in x-ray imaging applications 有权
标题翻译：用于估计x射线成像应用中的统计噪声图的系统和方法
公开(公告)号：US09076237B2
公开(公告)日：2015-07-07
申请号：US13796783
申请日：2013-03-12
申请人： Wisconsin Alumni Research Foundation
发明人： Guang-Hong Chen , Jie Tang
IPC分类号： G06T5/00 , G06T5/50 , A61B6/03 , A61B6/00
CPC分类号： G06T5/50 , A61B6/032 , A61B6/508 , A61B6/5205 , A61B6/5258 , G06T5/002 , G06T11/005 , G06T2207/10081 , G06T2207/10112 , G06T2207/10116 , G06T2207/20216
摘要： Described here are a system and method for producing a statistical noise map that indicates the noise present in data acquired with an x-ray imaging system, such as an x-ray computed tomography system, an x-ray tomosynthesis system, a C-arm x-ray imaging system, and so on. In general, an image is reconstructed from the acquired data using, for example, any standard filtered back projection (“FBP”) image reconstruction algorithm. This image is used as a base line to estimate a noise standard distribution map. The raw projection data represents a typical measurement among many repeated measurements under the same experimental conditions; therefore, the measured projection data can be used to numerically generate an ensemble of many (e.g., twenty or more) noisy projection data sets. These noisy projection data sets are then used to reconstruct noisy images and from these noisy images and the original image, the statistical noise map can be computed.
摘要翻译：这里描述了一种用于产生统计噪声图的系统和方法，该统计噪声图指示了使用x射线成像系统（例如x射线计算机断层摄影系统，x射线断层合成系统，C臂）获得的数据中存在的噪声 x射线成像系统等。一般来说，使用例如任何标准滤波反投影（“FBP”）图像重建算法从所获取的数据重建图像。该图像用作基线以估计噪声标准分布图。原始投影数据表示在相同实验条件下的许多重复测量中的典型测量; 因此，测量的投影数据可以用于数字地生成许多（例如，二十个或更多）噪声投影数据集合的集合。然后，这些噪声投影数据集用于重建噪声图像，并且从这些噪声图像和原始图像中可以计算统计噪声图。

37. 发明申请

US20140270454A1 SYSTEM AND METHOD FOR ESTIMATING A STATISTICAL NOISE MAP IN X-RAY IMAGING APPLICATIONS 有权
标题翻译：用于估计X射线成像应用中的统计噪声图的系统和方法
公开(公告)号：US20140270454A1
公开(公告)日：2014-09-18
申请号：US13796783
申请日：2013-03-12
申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION
发明人： Guang-Hong Chen , Jie Tang
IPC分类号： G06T7/00
CPC分类号： G06T5/50 , A61B6/032 , A61B6/508 , A61B6/5205 , A61B6/5258 , G06T5/002 , G06T11/005 , G06T2207/10081 , G06T2207/10112 , G06T2207/10116 , G06T2207/20216
摘要： Described here are a system and method for producing a statistical noise map that indicates the noise present in data acquired with an x-ray imaging system, such as an x-ray computed tomography system, an x-ray tomosynthesis system, a C-arm x-ray imaging system, and so on. In general, an image is reconstructed from the acquired data using, for example, any standard filtered back projection (“FBP”) image reconstruction algorithm. This image is used as a base line to estimate a noise standard distribution map. The raw projection data represents a typical measurement among many repeated measurements under the same experimental conditions; therefore, the measured projection data can be used to numerically generate an ensemble of many (e.g., twenty or more) noisy projection data sets. These noisy projection data sets are then used to reconstruct noisy images and from these noisy images and the original image, the statistical noise map can be computed.
摘要翻译：这里描述了一种用于产生统计噪声图的系统和方法，该统计噪声图指示了使用x射线成像系统（例如x射线计算机断层摄影系统，x射线断层合成系统，C臂）获得的数据中存在的噪声 x射线成像系统等。一般来说，使用例如任何标准滤波反投影（“FBP”）图像重建算法从所获取的数据重建图像。该图像用作基线以估计噪声标准分布图。原始投影数据表示在相同实验条件下的许多重复测量中的典型测量; 因此，测量的投影数据可以用于数字地生成许多（例如，二十个或更多）噪声投影数据集合的集合。然后，这些噪声投影数据集用于重建噪声图像，并且从这些噪声图像和原始图像中可以计算统计噪声图。

38. 发明申请

US20140270439A1 SYSTEM AND METHOD FOR SIMULATANEOUS IMAGE ARTIFACT REDUCTION AND TOMOGRAPHIC RECONSTRUCTION 有权
标题翻译：用于模拟图像减少和图像重建的系统和方法
公开(公告)号：US20140270439A1
公开(公告)日：2014-09-18
申请号：US13828103
申请日：2013-03-14
申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION
发明人： Guang-Hong Chen
IPC分类号： G06T11/00
CPC分类号： G06T11/003 , G06T11/006 , G06T2211/412 , G06T2211/424
摘要： Described here is a system and method for image reconstruction that can automatically and iteratively produce multiple images from one set of acquired data, in which each of these multiple images corresponds to a subset of the acquired data that is self-consistent, but inconsistent with other subsets of the acquired data. The image reconstruction includes iteratively minimizing the rank of an image matrix whose columns each correspond to a different image. The rank minimization is constrained subject to a consistency condition that enforces consistency between the forward projection of each column in the image matrix and a respective subset of the acquired data that contains data that is consistent with data in the subset, but inconsistent with data not in the subset.
摘要翻译：这里描述了一种用于图像重构的系统和方法，其可以从一组采集的数据自动和迭代地产生多个图像，其中这些多个图像中的每一个对应于所获取的数据的子集，其是自相矛盾的，但与其他的不一致获取的数据的子集。图像重建包括迭代地最小化其列各自对应于不同图像的图像矩阵的等级。排序最小化受制于一致性条件，强制图像矩阵中每列的前向投影与包含与该子集中的数据一致的数据的所获取数据的相应子集之间的一致性一致，但与不在子集。

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