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41. 发明授权

US06737523B1 Nucleic acids comprising regions of the rat PEG-3 promoter that display elevated expression in human cancer cells and uses thereof 有权
标题翻译：包含显示人癌细胞中升高的表达的大鼠PEG-3启动子区域的核酸及其用途
公开(公告)号：US06737523B1
公开(公告)日：2004-05-18
申请号：US09621781
申请日：2000-07-21
申请人： Paul B. Fisher , Zao-Zhong Su
发明人： Paul B. Fisher , Zao-Zhong Su
IPC分类号： C07H2104
CPC分类号： G01N33/57496 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , A61K48/0058 , A61K2035/126 , A61K2035/128 , C07K14/47 , C12N15/85 , C12N2799/022 , C12N2830/002 , C12N2830/008 , C12N2830/85 , C40B30/04 , G01N33/68
摘要： This invention provides an isolated nucleic acid comprising a PEG-3 promoter comprising the nucleotide sequence of −270 to +194 of FIG. 2. The invention also provides a method for identifying an agent that modulates PEG-3 promoter activity using a cell which comprises a PEG-3 promoter operatively linked to a reporter gene, wherein reduced reporter gene expression in the presence of the agent is indicative of an agent that inhibits PEG-3 promoter activity and wherein increased reporter gene expression in the presence of the agent is indicative of an agent that enhances PEG-3 promoter activity. The invention provides a method for treating cancer in a subject which comprises administering a nucleic acid comprising a PEG-3 promoter operatively linked to a gene-of-interest, wherein the gene-of-interest is selectively expressed in cancerous cells in the subject and such expression results in growth suppression or death of the cancerous cells.
摘要翻译：本发明提供了包含PEG-3启动子的分离的核酸，其包含图17的-270至+ 194的核苷酸序列。本发明还提供了一种用于鉴定使用包含与报道基因可操作地连接的PEG-3启动子的细胞来调节PEG-3启动子活性的试剂的方法，其中在试剂存在下，报告基因表达降低表明抑制PEG-3启动子活性的试剂，并且其中在试剂存在下增加的报告基因表达指示增强PEG-3启动子活性的试剂。本发明提供了一种用于治疗受试者的癌症的方法，其包括施用包含可操作地连接到感兴趣的基因的PEG-3启动子的核酸，其中感兴趣的基因在受试者的癌细胞中选择性表达，这种表达导致癌细胞的生长抑制或死亡。

42. 发明授权

US06204001B1 Methods for determining compounds capable of inhibiting the activities of the Ha-Ras oncongene 失效
标题翻译：用于测定能够抑制Ha-Ras oncongene活性的化合物的方法
公开(公告)号：US06204001B1
公开(公告)日：2001-03-20
申请号：US08749737
申请日：1996-11-15
申请人： Paul B. Fisher , Zao-Zhong Su
发明人： Paul B. Fisher , Zao-Zhong Su
IPC分类号： G01N33574
CPC分类号： C07K14/82 , A61K38/00 , C07K14/4703
摘要： This invention provides a method for determining whether a compound is capable of suppressing ras functions comprising: (a) contacting an effective amount of the compound with Ha-ras transformed cloned rat embryo fibroblast cells under conditions permitting the compound to suppress ras functions in the cells; and (b) determining the expression or inhibition of certain indicator gene or genes, thereby determining whether the compound is capable of suppressing ras function. This invention further provides the determined compound and a pharmaceutical composition comprising the compound and a pharmaceutically acceptable carrier. This invention also provides methods for generating transcriptional switched Ha-ras transformed cloned rat embryo fibroblast cells. This invention also provides the generated cells and different uses of the cells.
摘要翻译：本发明提供了一种用于确定化合物是否能够抑制ras功能的方法，包括：（a）在允许化合物抑制细胞中的ras功能的条件下，使有效量的化合物与Ha-ras转化的克隆的大鼠胚胎成纤维细胞接触 ; 和（b）确定某些指示基因或基因的表达或抑制，从而确定该化合物是否能够抑制ras功能。本发明进一步提供所确定的化合物和包含该化合物和药学上可接受的载体的药物组合物。本发明还提供用于产生转录转录的Ha-ras转化的克隆的大鼠胚胎成纤维细胞的方法。本发明还提供所生成的细胞和细胞的不同用途。

43. 发明授权

US09575957B2 Recognizing chemical names in a chinese document 有权
标题翻译：在中文文件中认可化学名称
公开(公告)号：US09575957B2
公开(公告)日：2017-02-21
申请号：US13598692
申请日：2012-08-30
申请人： Ying Chen , Zhong Su , Xian Wu , Li Zhang
发明人： Ying Chen , Zhong Su , Xian Wu , Li Zhang
IPC分类号： G06F17/27
CPC分类号： G06F17/2765
摘要： A method and system for recognizing chemical names in a Chinese document. The method includes: receiving a Chinese document including chemical names; recognizing chemical name segments in the document; recognizing non-chemical name segments in the document; and combining the chemical name segments to get chemical names based on the recognized chemical name segments and non-chemical name segments. Specific embodiments of the present invention can effectively recognize chemical names from a chemical document.
摘要翻译：一种用于识别中文文献中化学名称的方法和系统。该方法包括：接收包含化学名称的中文文件; 识别文件中的化学名称部分; 识别文件中的非化学名称部分; 并结合化学名称段，根据公认的化学名称段和非化学名称段获得化学名称。本发明的具体实施方案可以有效地识别来自化学文献的化学名称。

44. 发明授权

US09058383B2 Document processing method and system 有权
标题翻译：文件处理方法和系统
公开(公告)号：US09058383B2
公开(公告)日：2015-06-16
申请号：US13608438
申请日：2012-09-10
申请人： Sheng Hua Bao , Jie Cui , Hui Su , Zhong Su , Li Zhang
发明人： Sheng Hua Bao , Jie Cui , Hui Su , Zhong Su , Li Zhang
IPC分类号： G06F7/00 , G06F17/30
CPC分类号： G06F17/30716 , G06F17/30011
摘要： A method and system for filtering a candidate document in a candidate document set are provided. The method includes receiving one or more entity word—topic word pairs and identifying one or more entity words of the candidate document and topic words. The method also includes determining whether to add the candidate document into a filtered document set using the entity words and topic words in the given entity word—topic word pairs and the identified entity words and topic words in the candidate document. The method further includes adding the candidate document into a filtered document set in response to determining that the candidate document should be added into the filtered document set.
摘要翻译：提供了一种用于过滤候选文档集中候选文档的方法和系统。该方法包括接收一个或多个实体字主题词对并识别候选文档和主题词的一个或多个实体单词。该方法还包括使用给定实体字主题词对中的实体单词和主题词以及候选文档中所识别的实体单词和主题词来确定是否将候选文档添加到过滤文档集中。该方法还包括响应于确定候选文档应该被添加到经过滤的文档集中而将候选文档添加到经过过滤的文档集中。

45. 发明授权

US08924491B2 Tracking message topics in an interactive messaging environment 有权
标题翻译：在交互式邮件环境中跟踪邮件主题
公开(公告)号：US08924491B2
公开(公告)日：2014-12-30
申请号：US13403472
申请日：2012-02-23
申请人： Keke Cai , HongLei Guo , Zhong Su , Hui Jia Zhu
发明人： Keke Cai , HongLei Guo , Zhong Su , Hui Jia Zhu
IPC分类号： G06F15/16 , H04L12/58
CPC分类号： H04L12/586 , H04L12/588 , H04L51/16 , H04L51/32
摘要： A method and apparatus for tracking a topic involved in a message in an interactive messaging environment containing a plurality of messages by combining with context messages associated with the message. The method includes the steps of: selecting a message from the plurality of messages contained in the interactive messaging environment; identifying context messages associated with the selected message from the plurality of messages contained in the interactive messaging environment; and grouping the selected message into one or more topic groups based on the identified context messages. The topic tracking method and apparatus of the invention can accurately determine similarities between messages in an interactive messaging environment such as microblog to perform topic tracking.
摘要翻译：一种用于通过与与所述消息相关联的上下文消息组合来跟踪包含多个消息的交互式消息收发环境中涉及到的主题的方法和装置。该方法包括以下步骤：从包含在交互消息环境中的多个消息中选择消息; 从所述交互式消息收发环境中包含的所述多个消息中识别与所选择的消息相关联的上下文消息; 以及基于所识别的上下文消息将所选择的消息分组为一个或多个主题组。本发明的主题跟踪方法和装置可以准确地确定诸如微博的交互式消息传递环境中的消息之间的相似性，以执行主题跟踪。

46. 发明授权

US08874604B2 Method and system for searching an electronic map 有权
标题翻译：搜索电子地图的方法和系统
公开(公告)号：US08874604B2
公开(公告)日：2014-10-28
申请号：US12871181
申请日：2010-08-30
申请人： Keke Cai , Rui Ma , Zhong Su , Xiao Xun Zhang , Hui Jia Zhu
发明人： Keke Cai , Rui Ma , Zhong Su , Xiao Xun Zhang , Hui Jia Zhu
IPC分类号： G06F17/30
CPC分类号： G06F17/3087
摘要： A method and system for searching an electronic map. The method includes the steps of: receiving a query entered by a user for searching the electronic map; extracting place names in the query; extracting in web pages searched on a computer network co-occurrence place names that co-occurred with the place names; selecting extension place names from the co-occurrence place names, thereby obtaining a set of extension place names; generating a set of queries, wherein the set of queries includes the query entered by the user, and includes a query obtained by replacing the place names in the query entered by the user with each extension place name in the set of extension place names respectively; and sending the set of queries to a map search engine.
摘要翻译：一种用于搜索电子地图的方法和系统。该方法包括以下步骤：接收用户输入的用于搜索电子地图的查询; 在查询中提取地名; 在与计算机网络上搜索的网页中提取与地名同时发生的同现地名; 从合并地名选择扩展名，从而获得一组扩展名; 生成一组查询，其中所述查询集合包括由用户输入的查询，并且包括通过分别在所述一组分机地名中替换由用户输入的查询中的每个分机地名的所述地名所获得的查询; 并将该组查询发送到地图搜索引擎。

47. 发明授权

US08838650B2 Method and apparatus for preprocessing a plurality of documents for search and for presenting search result 有权
标题翻译：用于预处理多个用于搜索的文档和用于呈现搜索结果的方法和装置
公开(公告)号：US08838650B2
公开(公告)日：2014-09-16
申请号：US11847285
申请日：2007-08-29
申请人： Ben Fei , Zhong Su , Qing Bo Wang , Li Zhang
发明人： Ben Fei , Zhong Su , Qing Bo Wang , Li Zhang
IPC分类号： G06F7/00
CPC分类号： G06F17/30864
摘要： A method and apparatus for preprocessing a plurality of documents for search and presenting search result and a system for searching documents that comprises these apparatuses. The search result, for example, includes at least one candidate document. The candidate document is assigned a tree structure representing its content. The tree structure includes at least one node. The method may include presenting at least a portion of the tree structure corresponded to the candidate document in the search result.
摘要翻译：一种用于预处理用于搜索和呈现搜索结果的多个文档的方法和装置，以及用于搜索包括这些装置的文档的系统。搜索结果例如包括至少一个候选文档。候选文件被分配一个表示其内容的树结构。树结构包括至少一个节点。该方法可以包括在搜索结果中呈现对应于候选文档的树结构的至少一部分。

48. 发明授权

US08768936B2 Method and apparatus for recommending information to users within a social network 有权
标题翻译：用于向社交网络内的用户推荐信息的方法和装置
公开(公告)号：US08768936B2
公开(公告)日：2014-07-01
申请号：US13160593
申请日：2011-06-15
申请人： Shenghua Bao , Jian Chen , Cheng En Lu , Rui Ma , Zhong Su
发明人： Shenghua Bao , Jian Chen , Cheng En Lu , Rui Ma , Zhong Su
IPC分类号： G06F17/30
CPC分类号： G06F17/30867 , H04L51/32
摘要： A method and an apparatus for recommending information to users within a social network. The method builds a recommendation list with at least one two-tuple, where each two-tuple comprises a target user name and an information item and ranks the recommendation list by using two-tuples in the recommendation list as a basic unit. By selecting a two-tuple in the recommendation list, the user can recommend a corresponding information item to a user represented by a target user name. An apparatus is also provided by using a builder for building for a user a recommendation list comprising at least one two-tuple and a sorter for ranking the recommendation list by using two-tuples in the recommendation list as a basic unit, such that, by selecting a two-tuple in the recommendation list.
摘要翻译：一种用于向社交网络内的用户推荐信息的方法和装置。该方法构建具有至少一个二元组的推荐列表，其中每个二元组包括目标用户名和信息项，并且通过使用推荐列表中的两元组作为基本单元对推荐列表进行排序。通过在推荐列表中选择二元组，用户可以向由目标用户名表示的用户推荐相应的信息项。还通过使用构建器来提供装置，用于为用户构建包括至少一个二元组和分类器的推荐列表，以通过使用推荐列表中的两元组作为基本单元来对推荐列表进行排名，使得通过在推荐列表中选择一个二元组。

49. 发明申请

US20140129220A1 SPEAKER AND CALL CHARACTERISTIC SENSITIVE OPEN VOICE SEARCH 有权
标题翻译：扬声器和呼叫特征敏感开放语音搜索
公开(公告)号：US20140129220A1
公开(公告)日：2014-05-08
申请号：US14152136
申请日：2014-01-10
申请人： Shilei Zhang , Shenghua Bao , Wen Liu , Yong Qin , Zhiwei Shuang , Jian Chen , Zhong Su , Qin Shi , William F. Ganong, III
发明人： Shilei Zhang , Shenghua Bao , Wen Liu , Yong Qin , Zhiwei Shuang , Jian Chen , Zhong Su , Qin Shi , William F. Ganong, III
IPC分类号： G10L15/26
CPC分类号： G10L15/26 , G06F17/30026 , G06F17/3053 , G06F17/30705 , G06F17/30867 , G10L15/18 , G10L15/1807 , G10L15/183 , G10L15/22
摘要： Techniques disclosed herein include systems and methods for open-domain voice-enabled searching that is speaker sensitive. Techniques include using speech information, speaker information, and information associated with a spoken query to enhance open voice search results. This includes integrating a textual index with a voice index to support the entire search cycle. Given a voice query, the system can execute two matching processes simultaneously. This can include a text matching process based on the output of speech recognition, as well as a voice matching process based on characteristics of a caller or user voicing a query. Characteristics of the caller can include output of voice feature extraction and metadata about the call. The system clusters callers according to these characteristics. The system can use specific voice and text clusters to modify speech recognition results, as well as modifying search results.
摘要翻译：本文公开的技术包括用于开放式语音启用搜索的扬声器敏感的系统和方法。技术包括使用语音信息，说话者信息和与口语查询相关联的信息来增强开放语音搜索结果。这包括将文本索引与语音索引集成以支持整个搜索周期。给定语音查询，系统可以同时执行两个匹配过程。这可以包括基于语音识别输出的文本匹配过程，以及基于呼叫者或用户发出查询的特征的语音匹配过程。呼叫者的特征可以包括语音特征提取的输出和关于呼叫的元数据。根据这些特点，系统集群呼叫者。系统可以使用特定的语音和文本集群来修改语音识别结果，以及修改搜索结果。

50. 发明授权

US08644605B2 Mapping colors of an image 失效
标题翻译：映射图像的颜色
公开(公告)号：US08644605B2
公开(公告)日：2014-02-04
申请号：US13572901
申请日：2012-08-13
申请人： Sheng Hua Bao , Jian Chen , Zhong Su , Xin Ying Yang
发明人： Sheng Hua Bao , Jian Chen , Zhong Su , Xin Ying Yang
IPC分类号： G06K9/34
CPC分类号： G06T7/0079 , H04N1/60 , H04N1/62
摘要： A method and system for mapping colors of an image. The method including the steps of: segmenting an image into a plurality of regions, so that pixels in each of the plurality of regions have a characteristic that meets a predetermined similarity; determining an initial contrast between adjacent regions in the plurality of regions; and transforming an initial color of each of the plurality of regions into a target color; where a target contrast between the adjacent regions in the plurality of regions is equal to or greater than the initial contrast or a difference between the target contrast and corresponding initial contrast is less than a predetermined threshold; and where at least one of the steps is carried out by a computer device.
摘要翻译：用于映射图像的颜色的方法和系统。该方法包括以下步骤：将图像分割成多个区域，使得多个区域中的每个区域中的像素具有满足预定相似度的特征; 确定所述多个区域中的相邻区域之间的初始对比度; 以及将所述多个区域中的每一个的初始颜色变换成目标颜色; 其中所述多个区域中的相邻区域之间的目标对比度等于或大于所述初始对比度，或者所述目标对比度和对应的初始对比度之间的差小于预定阈值; 并且其中至少一个步骤由计算机设备执行。

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