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51. 发明授权

US11097097B2 System amd method for individualizing neuromodulation 有权
公开(公告)号：US11097097B2
公开(公告)日：2021-08-24
申请号：US16667463
申请日：2019-10-29
申请人： Halo Neuro, Inc.
发明人： Brett Wingeier , Randall Lin , Daniel Toker
IPC分类号： A61N1/08 , A61N1/20 , A61N1/04 , A61N1/36 , A61B5/00 , A61B5/16 , A61B5/369
摘要： A system for individualizing neuromodulation includes a neurostimulation device having a set of electrodes, and an application executing on a user device. Additionally or alternatively, the system can include any or all of: a sensor system, a head-securing mechanism, a remote server, storage, an accessory device, and any other suitable component. A method for individualizing neuromodulation includes determining a task of interest to a user; determining a user skill level associated with the task; determining a set of goals; determining an individualized neuromodulation program comprising a neurostimulation pattern; and delivering the neurostimulation pattern to the user. Additionally or alternatively, the method can include any or all of: determining user progress; displaying user progress; receiving user feedback; determining and/or adapting neuromodulation program based on user progress and/or user feedback; and any other suitable process.

52. 发明授权

US11077305B2 Identification of compromised components in a medical system 有权
公开(公告)号：US11077305B2
公开(公告)日：2021-08-03
申请号：US15699873
申请日：2017-09-08
申请人： MEDTRONIC, INC.
发明人： Jonathon E. Giftakis , Timothy J. Denison , Paul H. Stypulkowski , Scott R. Stanslaski , Robert S. Raike , Mae Eng , David E. Linde , Thomas Adamski
IPC分类号： A61N1/36 , A61N1/05 , A61N1/08
摘要： In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.

53. 发明申请

US20210228878A1 Systems and Methods for Detecting Electrode Lead Proximity to Cochlear Tissue 有权
公开(公告)号：US20210228878A1
公开(公告)日：2021-07-29
申请号：US16972407
申请日：2018-06-19
申请人： Advanced Bionics AG
发明人： Kanthaiah Koka , Leonid M. Litvak
IPC分类号： A61N1/36 , A61N1/05 , A61N1/08 , A61N1/02
摘要： An exemplary sound processor within a cochlear implant system directs a cochlear implant to concurrently apply first and second pulses by way of first and second electrodes disposed on an electrode lead configured to be inserted into a cochlea of a patient. The first and second pulses have substantially equal magnitudes and opposite phases such that the application of the first and second pulses forms a dipole that generates a field. The sound processor further directs the cochlear implant to detect, by way of a third electrode disposed on the electrode lead, an energy magnitude of the field that reflects from cochlear tissue located within the field. Based on a difference between the detected energy magnitude of the field and a baseline energy magnitude of the field, the sound processor determines a proximity of the electrode lead to the cochlear tissue. Corresponding systems and methods are also disclosed.

54. 发明授权

US11071856B2 Advanced electrode array location evaluation 有权
公开(公告)号：US11071856B2
公开(公告)日：2021-07-27
申请号：US15936282
申请日：2018-03-26
申请人： Cochlear Limited
发明人： Ryan Orin Melman
IPC分类号： A61N1/36 , A61N1/05 , A61N1/08 , H04R25/00
摘要： A method, including sequentially activating a plurality of respective electrode pairs of an implanted cochlear implant, at least one of the electrodes of the respective electrode pairs being a respective electrode of an electrode array implanted in a cochlea, thereby generating respective localized electric fields, concurrently respectively measuring, for the plurality of activated respective electrode pairs, an electrical characteristic between the respective electrodes of the respective electrode pairs resulting from the respective localized electric fields, thereby obtaining a measurement set, determining, from the measurement set, a distance between the electrode array and a wall of the cochlea.

55. 发明授权

US11065442B2 Implantable medical device which may be controlled from central station 有权
公开(公告)号：US11065442B2
公开(公告)日：2021-07-20
申请号：US14816382
申请日：2015-08-03
申请人： Jeffrey A. Matos
发明人： Jeffrey A. Matos
IPC分类号： A61N1/08 , A61B5/08 , G16H40/67 , A61N1/372 , A61B5/00 , A61B5/0402 , G16H20/40 , A61N1/39 , A61N1/375 , A61B5/1172 , A61B5/021 , A61N1/362 , A61N1/37 , A61B5/1455
摘要： An implantable electrical stimulating device and system provides for a remote determination of the identity of the person in whom the stimulating device is implanted. The stimulating device may be a pacemaker, a defibrillator, another medical device or a non-medical device. The bases for the remote identification are (1) the comingling of (A) biologic identification information of the person linked to the stimulating device, and (B) information pertaining to a physiologic parameter (e.g. heart rate information) of that person, and (2) the modulation of the physiologic parameter by external information. Embodiments of the invention in which the stimulating device is external to the person are possible. By utilizing the apparatus providing for the remote identification of a person plus stimulating device, one aspect of secure communication—that based on reliable mutual identification of each participant in a communication—is achieved.

56. 发明授权

US11052242B1 MRI compatible lead 有权
公开(公告)号：US11052242B1
公开(公告)日：2021-07-06
申请号：US16404451
申请日：2019-05-06
申请人： Avery Biomedical Devices, Inc.
发明人： Dilys Gore
IPC分类号： A61N1/05 , A61N1/08
摘要： A lead wire assembly apparatus for an implantable medical device (IMD), the apparatus including a lead having first and second ends and a plurality of separate conductive segments serially located therebetween; a cover defining at least one cavity situated about ends of adjacent conductive segments; and a fluid located in the at least one cavity and coupling the adjacent conductive segments to each other. The fluid electrically couples adjacent conductive segments to pass driving signals of the implantable medical device. The fluid may further attenuate induced signals generated by radiofrequency (RF) signals of a magnetic resonance (MR) system.

57. 发明申请

US20210186866A1 SYSTEMS AND METHODS FOR DELIVERY OF A THERAPEUTIC AGENT 有权
公开(公告)号：US20210186866A1
公开(公告)日：2021-06-24
申请号：US17151938
申请日：2021-01-19
申请人： The Foundry, LLC
发明人： Mark E. Deem , Hanson Gifford
IPC分类号： A61K9/00 , A61K38/16 , A61K38/48 , A61K41/00 , A61N1/32 , A61N1/08 , A61N1/30 , A61N7/00 , A61B18/14 , A61B18/18 , A61N5/10 , A61M37/00
摘要： Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.

58. 发明申请

US20210178162A1 NEUROSTIMULATION METHOD AND SYSTEM FOR ACTIVE EMULATION OF PASSIVE DISCHARGE IN PRESENCE OF MRI/EMI INTERFERENCE 有权
公开(公告)号：US20210178162A1
公开(公告)日：2021-06-17
申请号：US17186630
申请日：2021-02-26
申请人： ADVANCED NEUROMODULATION SYSTEMS, INC.
发明人： Steven Boor , Daran DeShazo
IPC分类号： A61N1/36 , A61N1/08
摘要： A neurostimulation (NS) system and method are provided. The NS system includes an array of electrodes positioned within a patient. The array of electrodes includes an active electrode. The active electrode is configured to be a cathode electrode located proximate to neural tissue of interest that is associated with a target region. The NS system includes an anode electrode and an electromagnetic interference (EMI) antenna. A control circuit is configured to control delivery of a NS therapy during a therapy delivery interval. The NS therapy is to be delivered between the anode electrode and the active electrode. The NS system develops a residual voltage between the anode electrode and the active electrode over the therapy delivery interval. A current regulator (CR) circuit is connected to the cathode electrode. The CR circuit is configured to control current flow through the cathode electrodes. During a discharge operation, the control circuit is configured to manage the CR circuit to control a discharge current flow over the discharge operation to discharge the residual voltage after therapy delivery in a manner that follows an actively emulated passive discharge (AEPD) profile. During the discharge operation, the CR circuit is connected to the inactive electrode. The CR circuit receives, as a first input, an EMI feedback signal from the EMI antenna. The CR circuit is configured to regulate the discharge current flow through the active electrode based on the EMI feedback signal, to maintain the AEPD profile over the discharge operation while in a presence of an EMI event.

59. 发明申请

US20210169428A1 MOBILE APPLICATION TO PROMPT PHYSICAL ACTION TO MEASURE PHYSIOLOGIC RESPONSE IN IMPLANTABLE DEVICE 有权
公开(公告)号：US20210169428A1
公开(公告)日：2021-06-10
申请号：US17181199
申请日：2021-02-22
申请人： Medtronic, Inc.
发明人： Bruce D. Gunderson , Eduardo N. Warman
IPC分类号： A61B5/00 , A61B5/11 , A61N1/08 , A61N1/372 , A61B5/287 , A61B5/0205 , A61B5/0538 , A61B5/0215 , G08B1/08 , A61B5/08 , A61N1/36
摘要： A user equipment that includes a touchscreen, and at least one processor configured to generate first timestamp data based upon detection of a first touch event on the touchscreen, and second timestamp data based upon detection of a second touch event on the touchscreen, for calculation by a medical device system of a patient-specific functional status parameter associated with a Sit-To-Stand performance test over a time segment inclusively bounded by a first time defined by the first timestamp data and a second time defined by the second timestamp data.

60. 发明申请

US20210137578A1 CONTINUOUS WOUND DRESSING WITH PLASMA ELECTRODE 有权
公开(公告)号：US20210137578A1
公开(公告)日：2021-05-13
申请号：US16475814
申请日：2017-12-20
申请人： CINOGY GMBH
发明人： Mirko HAHNL , Karl-Otto STORCK , Leonhard TRUTWIG , Dirk WANDKE
IPC分类号： A61B18/04 , H05H1/24 , A61N1/04 , A61N1/44 , A61N1/08 , A61N1/32
摘要： The invention relates to a treatment device for dielectric harrier discharge plasma treatment of a wound surface or skin surface, having: a flexible, planar electrode assembly with at least one planar electrode (6, 6′) and a dielectric layer (5) which at least partially embeds the at least one electrode (6, 6′), has a contact side (7) facing the wound surface or skin surface and electrically shields the planar electrode (6, 6′) from the wound surface or skin surface such that only a dielectric barrier current can flow from the electrode (6, 6′) to the wound surface or skin surface; and a control device (2) which has a separate housing (25) and via which the electrode (6, 6′) can he connected to an operating voltage. The treatment device allows simpler wound treatment in that the assembly of electrode (6, 6′) and dielectric layer (5) is designed for uninterrupted contact with the wound surface or skin surface and that the housing (25) of the control device (2) can be fastened with a fastening device (3, 3′) to the body having the wound surface or skin surface.

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