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61. 发明申请

US20110137279A1 Fastening System 有权
标题翻译：紧固系统
公开(公告)号：US20110137279A1
公开(公告)日：2011-06-09
申请号：US13009879
申请日：2011-01-20
申请人： Thomas Alexander Horn , Mark James Kline , Kazuhiko Masuda , Hisashi Morimoto
发明人： Thomas Alexander Horn , Mark James Kline , Kazuhiko Masuda , Hisashi Morimoto
IPC分类号： A61F13/62
CPC分类号： A44B18/0003 , A44B18/0046 , A44B18/0073 , A44B18/008 , A61F13/62 , A61F13/622 , A61F13/627 , Y10T24/27 , Y10T24/2725 , Y10T24/275 , Y10T428/24017
摘要： A mechanical fastening system having an engaging component and a receiving component. The receiving component has a first bond line, a second bond line, a bond zone, and a plurality of consecutive sweep regions. The second bond line is disposed adjacent to the first bond line such that a portion of the second bond line overlaps a portion of the first bond line. The bond zone circumscribes the first bond line and the second bond line. The plurality of consecutive sweep regions are disposed within the bond zone. At least one sweep region includes a portion of both the first bond line and the second bond line, and the remaining sweep regions include at least a portion of the first or the second bond lines. The receiving component has a bond ratio greater than or equal to about 1 and less than or equal to about 20.
摘要翻译：一种具有接合部件和接收部件的机械紧固系统。接收部件具有第一接合线，第二接合线，接合区和多个连续的扫掠区。第二结合线设置成与第一结合线相邻，使得第二结合线的一部分与第一结合线的一部分重叠。粘结区围绕第一粘结线和第二粘合线。多个连续的扫描区域设置在粘结区域内。至少一个扫描区域包括第一结合线和第二结合线的一部分，并且剩余的扫掠区域包括第一或第二结合线的至少一部分。接收组分具有大于或等于约1且小于或等于约20的键合比。

62. 发明申请

US20110136244A1 METHODS AND KITS FOR A COLOR CHANGING SAMPLE DILUENT 审中-公开
标题翻译：颜色变化稀释液的方法和工具
公开(公告)号：US20110136244A1
公开(公告)日：2011-06-09
申请号：US12811906
申请日：2009-01-28
申请人： Mark James Kopnitsky
发明人： Mark James Kopnitsky
IPC分类号： G01N33/50 , G01N21/00
CPC分类号： G01N21/78
摘要： The present invention provides methods and kits in assessing color change in a series of reaction mixes while providing significant improvement in the amount of non-specific binding. The method provides for a dramatic color change when incorporated into a series of assays or used in an individual reaction. The color change enables quick visual tracking and verification of the addition of reaction components. Further, the color change allows for verification that an instrument is performing correctly in reagent addition during an automated assay. In one embodiment, the reaction mix is initially a yellowish color. Upon adding serum or plasma, the resulting solution undergoes a dramatic color change to blue-purple, allowing for easy visual verification. Color change depends upon pH shifts in the sample preparation upon addition of serum or plasma. The method is useful whenever two or more reagents are combined and confirmation of the combination is required.
摘要翻译：本发明提供了评估一系列反应混合物中的颜色变化的方法和试剂盒，同时提供非特异性结合量的显着改善。该方法当并入一系列测定中或在单个反应中使用时提供显着的颜色变化。颜色变化可以快速的视觉跟踪和验证反应组分的添加。此外，颜色变化允许验证仪器在自动测定期间在试剂添加中正确地执行。在一个实施方案中，反应混合物最初是淡黄色的。加入血清或血浆后，所得溶液经蓝色紫色显着变色，容易进行目视验证。颜色变化取决于添加血清或血浆时样品制剂中的pH变化。当组合两种或多种试剂并需要确认组合时，该方法是有用的。

63. 发明申请

US20110111399A1 Methods And Compositions Including Diagnostic Kits For The Detection of Staphylococcus Aureus 审中-公开
标题翻译：包括用于检测金黄色葡萄球菌的诊断试剂盒的方法和组合物
公开(公告)号：US20110111399A1
公开(公告)日：2011-05-12
申请号：US12809086
申请日：2008-12-23
申请人： Shawn Mark O'Hara , Mark James Kopnitsky
发明人： Shawn Mark O'Hara , Mark James Kopnitsky
IPC分类号： C12Q1/68
CPC分类号： C12Q1/689 , C12Q1/686
摘要： Methods and compositions, including diagnostic kits, for the detection of Staphylococcus Aureus (SA) and clinically important antibiotic resistant forms thereof, such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Staphylococcus aureus (VRSA), mupirocin-resistant Staphylococcus aureus (mupSA), and the like, from individuals in a sample population are disclosed Also disclosed are cost effective methods and kits for bacterial sampling and analysis via inherent and expeditious SA cell disruption methods followed by Direct PCR, circumventing the need, expense and contamination πsks associated with DNA isolation methods These improved methods in conjunction with SA prevalence analysis are applied so as to eliminate the approximately 70% of samples in the human population which do not carry SA (SA negative), followed by a second more costly test for antibiotic resistant forms thereof, such as amplification to confirm for presence of MRSA or other target disease
摘要翻译：用于检测金黄色葡萄球菌（SA）和其临床重要的抗生素抗性形式的方法和组合物，包括耐甲氧西林金黄色葡萄球菌（MRSA），耐万古霉素金黄色葡萄球菌（VRSA），金霉素耐金黄葡萄球菌（Staphylococcus aureus）（mupSA）等来自样本群体中的个体披露还公开了经由固有和快速的SA细胞破碎方法进行细菌抽样和分析的成本有效的方法和试剂盒，其后为直接PCR，绕过需要，费用和污染＆pgr ;与DNA分离方法相关的sks应用这些与SA流行率分析相结合的改进方法，以消除人体中不携带SA（SA阴性）的大约70％的样品，然后进行第二次更昂贵的测试抗生素抗性形式，例如扩增以证实存在MRSA或其他目标疾病 se

64. 发明申请

US20110092947A1 Wearable Article with Extensible Fastening Member Having Stress Distribution Features and/or Fastening Combination Performance Characteristics, and Method of Testing and Selecting Fastening Combination Performance Characteristics 有权
标题翻译：具有应力分布特征和/或紧固组合性能特征的可伸缩紧固件的可穿戴物品以及紧固组合性能特性的测试和选择方法
公开(公告)号：US20110092947A1
公开(公告)日：2011-04-21
申请号：US12904220
申请日：2010-10-14
申请人： Mark James Kline , Oliver Edwin Clarke Mason
发明人： Mark James Kline , Oliver Edwin Clarke Mason
IPC分类号： A61F13/62
CPC分类号： G01N19/04 , A61F13/49015 , A61F13/62 , A61F13/627 , G01N2203/0016 , G01N2203/0025 , G01N2203/0091
摘要： A wearable article with an extensible fastening member having a fastener proximate its end is disclosed. The fastening member may be highly extensible, and may have construction features and shape characteristics that affect distribution of force components when the fastener is in use, and reduce the chances of buckling or flipping of the fastening member along its edges, and the chances that the edges of the fastener will be lifted away from a surface to which it is attached. The fastener and material forming an accompanying landing zone on the article may be selected to form a fastening combination having performance attributes that provide further resistance to unintended pop-off under wearing conditions.
摘要翻译：公开了一种具有靠近其端部的紧固件的可伸展紧固构件的可穿戴物品。紧固构件可以是高度可延伸的，并且可以具有影响紧固件在使用时影响力分量分布的结构特征和形状特征，并且减小紧固构件沿其边缘的弯曲或翻转的机会，以及紧固件的边缘将从其附接的表面提升离开。可以选择在制品上形成附着的着陆区的紧固件和材料以形成具有性能属性的紧固组合，其在穿着条件下提供进一步抵抗意外弹出的进一步阻力。

65. 发明授权

US07895718B2 Fastening system 有权
标题翻译：紧固系统
公开(公告)号：US07895718B2
公开(公告)日：2011-03-01
申请号：US11710216
申请日：2007-02-23
申请人： Thomas Alexander Horn , Mark James Kline , Kazuhiko Masuda , Hisashi Morimoto
发明人： Thomas Alexander Horn , Mark James Kline , Kazuhiko Masuda , Hisashi Morimoto
IPC分类号： A44B21/00 , B32B3/06
CPC分类号： A44B18/0003 , A44B18/0046 , A44B18/0073 , A44B18/008 , A61F13/62 , A61F13/622 , A61F13/627 , Y10T24/27 , Y10T24/2725 , Y10T24/275 , Y10T428/24017
摘要： A mechanical fastening system having an engaging component and a receiving component. The receiving component has a first bond line, a second bond line, a bond zone, and a plurality of consecutive sweep regions. The second bond line is disposed adjacent to the first bond line such that a portion of the second bond line overlaps a portion of the first bond line. The bond zone circumscribes the first bond line and the second bond line. The plurality of consecutive sweep regions are disposed within the bond zone. At least one sweep region includes a portion of both the first bond line and the second bond line, and the remaining sweep regions include at least a portion of the first or the second bond lines. The receiving component has a bond ratio greater than or equal to about 1 and less than or equal to about 20.
摘要翻译：一种具有接合部件和接收部件的机械紧固系统。接收部件具有第一接合线，第二接合线，接合区和多个连续的扫掠区。第二结合线设置成与第一结合线相邻，使得第二结合线的一部分与第一结合线的一部分重叠。粘结区围绕第一粘结线和第二粘合线。多个连续的扫描区域设置在粘结区域内。至少一个扫描区域包括第一结合线和第二结合线的一部分，并且剩余的扫掠区域包括第一或第二结合线的至少一部分。接收组分具有大于或等于约1且小于或等于约20的键合比。

66. 发明授权

US07888347B2 Pyrazolo [3,4-D]azepine derivatives as histamine H3 antagonists 失效
标题翻译：吡唑并[3,4-D]吖庚因衍生物作为组胺H3拮抗剂
公开(公告)号：US07888347B2
公开(公告)日：2011-02-15
申请号：US11994689
申请日：2006-07-04
申请人： Mark James Bamford , David Matthew Wilson
发明人： Mark James Bamford , David Matthew Wilson
IPC分类号： A61P25/28 , A61K31/55 , C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates to novel pyrazole derivatives of formula I having pharmacological activity as H3 antagonists processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
摘要翻译：本发明涉及具有药理学活性的式I的吡唑衍生物，其具有作为其制备的H3拮抗剂的方法，含有它们的组合物及其在治疗神经和精神疾病中的用途。

67. 发明授权

US07888344B2 Fused thiazole derivatives as kinase inhibitors 有权
标题翻译：融合噻唑衍生物作为激酶抑制剂
公开(公告)号：US07888344B2
公开(公告)日：2011-02-15
申请号：US11912801
申请日：2006-04-25
申请人： Rikki Peter Alexander , Pavandeep Aujla , Mark James Batchelor , Daniel Christopher Brookings , George Martin Buckley , Karen Viviane Lucile Crepy , Claire Louise Kulisa , James Petrie Turner
发明人： Rikki Peter Alexander , Pavandeep Aujla , Mark James Batchelor , Daniel Christopher Brookings , George Martin Buckley , Karen Viviane Lucile Crepy , Claire Louise Kulisa , James Petrie Turner
IPC分类号： A61K31/55 , A61K31/535 , C07D498/04 , C07D413/14
CPC分类号： C07D277/82 , A61K31/4184 , A61K31/4188 , A61K31/55 , C07D417/04 , C07D417/14 , C07D471/04 , C07D513/04
摘要： A series of 5,6-dihydro-1,3-benzothiazol-7(4H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PD kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
摘要翻译：通过任选取代的吗啉-4-基部分在2位被取代的一系列5,6-二氢-1,3-苯并噻唑-7（4H） - 酮衍生物及其类似物是选择性抑制剂因此PD激酶在医学上有益，例如在治疗炎症，自身免疫，心血管，神经变性，代谢，肿瘤，伤害性或眼科疾病中。

68. 发明授权

US07868813B2 Multi-use bearing and range line 有权
标题翻译：多用途轴承和量程线
公开(公告)号：US07868813B2
公开(公告)日：2011-01-11
申请号：US12381011
申请日：2009-03-05
申请人： Mark James O'Flynn , Lillian Chang , Virginie Bernard Blond
发明人： Mark James O'Flynn , Lillian Chang , Virginie Bernard Blond
IPC分类号： G01S13/93 , G01S7/22
CPC分类号： G01S7/22 , G08G5/0082
摘要： A method (400), a system and a computer program product are disclosed for graphically displaying air traffic control information in an air traffic control system. Information about objects in an air traffic control environment is compiled and calculated (410). Tokens (e.g., text, icons, images, or other symbols) corresponding to the objects in the air traffic control environment are displayed (420). At least two objects are selectively designated (430) in combination as a source object and a target object connected by a bearing and range line token (210, 220, 230, 240). Air traffic control information (212, 222, 232, 242) about the combination of objects associated with the bearing and range line token dependent upon the combination of objects designated in the combination is displayed (440). The displayed air traffic control information is required decision making information to enable an air traffic controller to manage air traffic. Display of the air traffic management information is dynamically updated (450) upon any change of the designated objects.
摘要翻译：公开了一种用于在空中交通管制系统中图形显示空中交通管制信息的方法（400），系统和计算机程序产品。有关空中交通管制环境中的物体的信息被编译和计算（410）。显示对应于空中交通管制环境中的对象的令牌（例如，文本，图标，图像或其他符号）（420）。选择性地将至少两个对象（430）组合指定为源对象和通过轴承和范围线令牌（210,220,230,240）连接的目标对象。显示关于与组合中指定的对象的组合相关联的与方位和范围行令牌相关联的对象的组合的空中交通管制信息（212,222,232,242）（440）。显示的空中交通管制信息是需要的决策信息，使得空中交通管制员能够管理空中交通。任何更改指定对象后，空中交通管理信息的显示将被动态更新（450）。

69. 发明申请

US20110002111A1 PROTECTION APPARATUS, METHOD OF LOCATING A SUPERCONDUCTIVE MAGNET UNIT AND SUPERCONDUCTIVE MAGNET UNIT APPARATUS 有权
标题翻译：保护装置，定位磁铁单元和超导磁体装置的定位方法
公开(公告)号：US20110002111A1
公开(公告)日：2011-01-06
申请号：US12498060
申请日：2009-07-06
申请人： Matthew Hobbs , Mark James Le Feuvre , Nicholas Mann , Philip Smith , Neil Charles Tigwell , Frank Zeuch
发明人： Matthew Hobbs , Mark James Le Feuvre , Nicholas Mann , Philip Smith , Neil Charles Tigwell , Frank Zeuch
IPC分类号： H05K7/18 , A47B96/00 , B66F13/00 , F16M13/00 , A47B97/00 , B65G61/00
CPC分类号： B66C1/62 , B66F13/00
摘要： A protection apparatus for a superconductive magnet unit has a support frame for location relative to a portion of the superconductive magnet unit. The support frame is arranged to carry a buffer for protecting the superconductive magnet unit from a shock load.
摘要翻译：用于超导磁体单元的保护装置具有用于相对于超导磁体单元的一部分定位的支撑框架。支撑框架布置成承载用于保护超导磁体单元免受冲击负荷的缓冲器。

70. 发明申请

US20100298802A1 Attachment Areas for Wearable Absorbent Articles 有权
标题翻译：可穿戴吸收制品的附件区域
公开(公告)号：US20100298802A1
公开(公告)日：2010-11-25
申请号：US12468633
申请日：2009-05-19
申请人： Mark James Kline , Nezam Malakouti , John Glasgow Burns, JR.
发明人： Mark James Kline , Nezam Malakouti , John Glasgow Burns, JR.
IPC分类号： A61F13/45 , A61F13/56
CPC分类号： A61F13/539 , A61F13/51464 , A61F2013/49063
摘要： A wearable absorbent article comprises an outer cover and an absorbent core assembly. At least a portion of the outer cover is joined to the absorbent core assembly over at least a first attachment area and a second attachment area. The overall lateral width of the second attachment area is less than the overall lateral width of the first attachment area. At least a portion of the second attachment area is disposed in a hip region of the article. The first attachment area is disposed longitudinally outboard from the second attachment area.
摘要翻译：一种可穿戴的吸收制品包括外盖和吸收芯组件。外盖的至少一部分在至少第一附接区域和第二附接区域上连接到吸收芯组件。第二附接区域的总横向宽度小于第一附接区域的整个横向宽度。第二附接区域的至少一部分设置在物品的臀部区域中。第一附接区域从第二附接区域纵向设置在外侧。

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