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61. 发明申请

US20140194964A1 LOW IMPEDANCE OXIDE RESISTANT GROUNDED CAPACITOR FOR AN AIMD 有权
标题翻译：用于AIMD的低阻抗氧化物接地电容器
公开(公告)号：US20140194964A1
公开(公告)日：2014-07-10
申请号：US14202653
申请日：2014-03-10
申请人： GREATBATCH LTD.
发明人： Jason Woods , Richard L. Brendel , Robert A. Stevenson , Christopher M. Williams , Robert Naugler , Christine A. Frysz
IPC分类号： A61N1/08
CPC分类号： A61N1/3754 , H01G2/02 , H01G4/228 , H01G4/35 , H01G4/40 , H01R13/7195 , H03H1/0007 , H03H7/1766 , H03H2001/0042 , H03H2001/0085
摘要： A hermetically sealed filtered feedthrough assembly for an AIMD includes an insulator hermetically sealed to a conductive ferrule or housing. A conductor is hermetically sealed and disposed through the insulator in non-conductive relation to the conductive ferrule or housing between a body fluid side and a device side. A feedthrough capacitor is disposed on the device side. A first low impedance electrical connection is between a first end metallization of the capacitor and the conductor. A second low impedance electrical connection is between a second end metallization of the capacitor and the ferrule or housing. The second low impedance electrical connection includes an oxide-resistant metal addition attached directly to the ferrule or housing and an electrical connection coupling the second end metallization electrically and physically directly to the oxide-resistant metal addition.
摘要翻译：用于AIMD的气密密封的过滤馈通组件包括密封到导电套圈或壳体的绝缘体。导体被气密地密封并且通过绝缘体以非导电关系设置在导体套管或壳体之间，在体液侧和器件侧之间。馈通电容器设置在器件侧。第一低阻抗电连接在电容器的第一端金属化和导体之间。第二低阻抗电连接在电容器的第二端金属化和套圈或壳体之间。第二低阻抗电连接包括直接连接到套圈或壳体的耐氧化金属添加剂和将第二端金属化物电和物理直接耦合到耐氧化金属添加物的电连接。

62. 发明授权

US08765113B2 Peptide based antimicrobial coating 有权
标题翻译：基于肽的抗菌涂层
公开(公告)号：US08765113B2
公开(公告)日：2014-07-01
申请号：US13534164
申请日：2012-06-27
申请人： Jan J. Lewandowski , Yubaio Liu
发明人： Jan J. Lewandowski , Yubaio Liu
IPC分类号： A01P1/00 , A01N37/46 , C08F26/02 , C08F8/30 , A61L27/54 , A61L29/16 , A61L31/16 , A61L33/12 , A61L28/00
CPC分类号： A61L33/12 , A61L27/54 , A61L28/0038 , A61L29/16 , A61L31/16 , A61L2300/25 , A61L2300/404
摘要： A comb-like surfactant polymer for changing the surface properties of biomaterials is described. The surfactant polymer comprises a polymeric backbone of repeating monomeric units having functional groups for chemically attaching to side chains, a plurality of hydrophobic side chains attached to the backbone via the functional groups and a plurality of hydrophilic side chains chemically attached via functional groups to the polymeric backbone. The hydrophilic side chains providing anti-thrombogenic properties to the surfactant. An antimicrobial agent selectively attached to some hydrophilic side chains thereby providing additional antimicrobial properties to the surfactant. The surfactant polymer may be applied to the surface of medical devices to reduce the surfaces thrombogenicity and decrease the number of microorganisms on the surface.
摘要翻译：描述了用于改变生物材料的表面性质的梳状表面活性剂聚合物。表面活性剂聚合物包含具有用于化学连接到侧链的具有官能团的重复单体单元的聚合物主链，经由官能团连接到主链上的多个疏水侧链和通过官能团化学连接到聚合物上的多个亲水侧链骨干。亲水侧链为表面活性剂提供抗血栓形成性质。选择性地连接到一些亲水侧链的抗微生物剂，从而为表面活性剂提供额外的抗微生物性质。可以将表面活性剂聚合物施加到医疗装置的表面以降低表面血栓形成并减少表面上的微生物数量。

63. 发明申请

US20140137403A1 TEMPORARY STIMULATION LEAD WITH POLYMER ELECTRODES AND METHOD OF MANUFACTURE 有权
标题翻译：具有聚合物电极的临时刺激引线和制造方法
公开(公告)号：US20140137403A1
公开(公告)日：2014-05-22
申请号：US14166161
申请日：2014-01-28
申请人： Greatbatch Ltd.
发明人： JOHN M. SWOYER
IPC分类号： A61N1/05 , A61M5/00
CPC分类号： A61N1/05 , A61M5/00 , A61N1/0529 , A61N1/056 , A61N1/306 , A61N1/375
摘要： A temporary medical lead in which stimulating electrical energy is transmitted to body tissue through the lead electrodes via ionic conduction within the hydrogel material is described. The hydrophilic hydrogel material consists of a porous structure into which conductive salt ions are diffused. In addition the structure of the hydrogel material can be loaded with a single or combination of therapeutic drugs which is elutable from the electrode.
摘要翻译：描述了临时医疗用铅，其中通过水凝胶材料内的离子传导，刺激电能通过引线电极传递到身体组织。亲水性水凝胶材料由导电盐离子扩散到其中的多孔结构组成。此外，水凝胶材料的结构可以加载可从电极中洗脱的单一或组合的治疗药物。

64. 发明授权

US08714056B2 Torque limiting mechanism with lock bushing 有权
标题翻译：带锁紧套的转矩限制机构
公开(公告)号：US08714056B2
公开(公告)日：2014-05-06
申请号：US13224659
申请日：2011-09-02
申请人： Steve Landowski
发明人： Steve Landowski
IPC分类号： B25B23/143
CPC分类号： B25B23/1427 , A61B17/8875 , A61B2090/031 , B25B23/141 , F16D1/112 , F16D7/08 , F16D43/206
摘要： A torque limiting mechanism used for securing fasteners is described. The torque limiting mechanism consists of a shaft, a torque gear having a plurality of ball bearings, a threshold bearing and a variable force applying subassembly. The torque limiting mechanism further consisting of a lock bushing and retaining ring placed circumferentially around the proximal end of the shaft. The lock bushing and retaining ring reduce structural misalignments and increase the accuracy of the device.
摘要翻译：描述了用于固定紧固件的扭矩限制机构。转矩限制机构包括轴，具有多个球轴承的转矩齿轮，阈值轴承和可变力施加子组件。转矩限制机构还包括围绕轴的近端周向放置的锁定衬套和保持环。锁紧套管和固定环可减少结构不对准，提高设备的精度。

65. 发明申请

US20140094871A1 DIGITAL CONTROL FOR PULSE GENERATORS 有权
标题翻译：脉冲发生器数字控制
公开(公告)号：US20140094871A1
公开(公告)日：2014-04-03
申请号：US14041082
申请日：2013-09-30
申请人： Greatbatch Ltd.
发明人： Stephen C. Trier , Jeffrey A. Weisgarber , Richard J. Polefko , David J. Howard
IPC分类号： A61N1/36
CPC分类号： A61N1/36125 , A61N1/36 , A61N1/36071 , A61N1/36128
摘要： A controller for implementing a method, device and/or system for generating arbitrary waveforms of a desired shape that can be used for generating a stimulation pulse for medical purposes such as for spinal cord stimulation therapy, where such arbitrary waveforms can also be used for charge balancing purposes.
摘要翻译：一种用于实现用于产生可用于医疗目的的刺激脉冲（例如用于脊髓刺激治疗）的期望形状的任意波形的方法，装置和/或系统的控制器，其中这种任意波形也可用于充电平衡目的。

66. 发明授权

US08685568B2 Lithium/fluorinated carbon cell for high-rate pulsatlie applications 有权
标题翻译：用于高速脉冲应用的锂/氟化碳电池
公开(公告)号：US08685568B2
公开(公告)日：2014-04-01
申请号：US11668500
申请日：2007-01-30
申请人： Paul Krehl , Steven Davis , Robert Rubino , Hong Gan , Esther S. Takeuchi
发明人： Paul Krehl , Steven Davis , Robert Rubino , Hong Gan , Esther S. Takeuchi
IPC分类号： H01M4/13 , H01M4/82
CPC分类号： H01M10/0569 , H01M4/133 , H01M4/583 , H01M4/5835 , H01M4/622 , H01M4/625 , H01M4/626 , H01M10/052 , H01M10/0568 , H01M2004/028 , Y10T29/49108
摘要： The current invention describes a lithium/carbon monofluoride (Li/CFx) cell capable of delivering sufficient power to supply an ICD or similar demanding device. The cell exhibits the typical excellent long-term stability and predictability of the CFx system, as well as its high energy density (greater than about 300 Ah/cc, greater than about 600 Wh/cc). Additionally, the cell is capable of delivering about 0.5 W/cc of cathode volume for greater than 5 seconds with a voltage above 1.70 V (FIG. 1). The following invention embodiments can be applied individually or in conjunction with each other.
摘要翻译：本发明描述了一种锂/碳一氟化物（Li / CFx）电池，其能够提供足够的电力来提供ICD或类似苛刻的装置。该电池表现出CFx系统典型的优异的长期稳定性和可预测性，以及其高能量密度（大于约300Ah / cc，大于约600Wh / cc）。另外，电池能够以高于1.70V的电压输送大约0.5W / cc的阴极体积大于5秒（图1）。以下发明实施例可以单独地或彼此结合使用。

67. 发明申请

US20140046414A1 LEAD WITH BRAIDED REINFORCEMENT 有权
公开(公告)号：US20140046414A1
公开(公告)日：2014-02-13
申请号：US13572081
申请日：2012-08-10
申请人： JAMES FINLEY , John Swoyer
发明人： JAMES FINLEY , John Swoyer
IPC分类号： A61N1/05 , H01R43/20
CPC分类号： A61N1/0551 , A61N1/05 , Y10T29/49208 , Y10T29/4921
摘要： A therapy delivery element configured for at least partial insertion in a living body. A braided structure surrounds the conductor assembly. A distal end of the braided structure is attached to an electrode assembly and a free floating proximal end is located near a connector assembly. An outer tubing surrounds the braided structure. The outer tubing includes a proximal end attached to the connector assembly and a distal end attached to the braided structure near the electrode assembly. A proximal tension force applied to the connector assembly acts substantially on the outer tubing and the conductor assembly and a proximal tension force applied to the free floating proximal end acts substantially on the braided structure.

68. 发明授权

US08649878B2 Temporary stimulation lead with polymer electrodes and method of manufacture 有权
标题翻译：临时刺激铅与聚合物电极和制造方法
公开(公告)号：US08649878B2
公开(公告)日：2014-02-11
申请号：US12818207
申请日：2010-06-18
申请人： John Swoyer
发明人： John Swoyer
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61M5/00 , A61N1/0529 , A61N1/056 , A61N1/306 , A61N1/375
摘要： A temporary medical lead in which stimulating electrical energy is transmitted to body tissue through the lead electrodes via ionic conduction within the hydrogel material. The structure of the hydrophilic hydrogel material consists of a porous structure into which conductive salt ions are diffused. In addition the structure of the hydrogel material can be loaded with a single or combination of therapeutic drugs from which is eluted from the electrode's surface.
摘要翻译：一种临时医疗用铅，其中通过水凝胶材料内的离子传导，刺激电能通过引线电极传递到身体组织。亲水性水凝胶材料的结构由导电盐离子扩散到其中的多孔结构组成。此外，水凝胶材料的结构可以装载有从电极表面洗脱的单一或组合的治疗药物。

69. 发明授权

US08648265B2 Full perimeter laser beam button weld of dissimilar materials 有权
标题翻译：不同材料的全周期激光束按钮焊接
公开(公告)号：US08648265B2
公开(公告)日：2014-02-11
申请号：US13155497
申请日：2011-06-08
申请人： Ken Talamine , Keith Seitz , Tim Weiskopff , Donald Anthony Bonitati
发明人： Ken Talamine , Keith Seitz , Tim Weiskopff , Donald Anthony Bonitati
IPC分类号： H02G3/18
CPC分类号： A61N1/3754 , H01G4/35
摘要： Terminal pins that include a refractory metal forming a full perimeter weld connected to a terminal block including a dissimilar metal incorporated into feedthrough filter capacitor assemblies are discussed. The feedthrough filter capacitor assemblies are particularly useful for incorporation into implantable medical devices such as cardiac pacemakers, cardioverter defibrillators, and the like, to decouple and shield internal electronic components of the medical device from undesirable electromagnetic interference (EMI) signals.
摘要翻译：讨论了包括连接到包括并入馈通滤波电容器组件中的不同金属的端子块的完整周边焊接的难熔金属的端子引脚。馈通滤波电容器组件特别可用于结合到诸如心脏起搏器，心律转复除颤器等的可植入医疗装置中，以将医疗装置的内部电子部件分离和屏蔽以免受不良电磁干扰（EMI）信号的影响。

70. 发明申请

US20140031909A1 MINIMALLY INVASIVE METHODS FOR IMPLANTING A SACRAL STIMULATION LEAD 有权
标题翻译：最小的入侵方法，用于植入SACRAL刺激引线
公开(公告)号：US20140031909A1
公开(公告)日：2014-01-30
申请号：US14033592
申请日：2013-09-23
申请人： Greatbatch Ltd.
发明人： Qingshan Ye , John M. Swoyer
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61N1/00 , A61N1/0558 , A61N1/36057
摘要： Methods and apparatus for implanting a neural stimulation lead in a patient's body are described. A lead assembly comprises a pointed-tip stylet, a stimulation lead, and an optional tube to deploy a fixation element attached to the lead. One embodiment of the implant methods starts with inserting the pointed-tip lead assembly directly into tissue. After the desired implant position is determined, the pointed-tip component is separated from the stimulation lead and removed from the tissue, leaving the stimulation lead implanted. After confirmation that the stimulation lead is in the right, tissue location, the pointed-tip component is removed from the body, leaving the stimulation lead in place. The stimulation lead can be connected to a neurostimulator to delivery therapies to treat neural disorders, such as urinary control disorders, fecal control disorders, sexual, dysfunction, and pelvic pain, etc.
摘要翻译：描述了将神经刺激引线植入患者体内的方法和装置。引线组件包括尖尖探针，刺激引线和用于展开附接到引线的固定元件的可选管。植入方法的一个实施方案是将尖尖引线组件直接插入组织中。在确定期望的植入位置之后，将尖端部件与刺激引线分离并从组织中移出，留下刺激引线。在确认刺激引线在右侧，组织位置之后，将尖端部件从身体移除，使刺激引线保持原位。刺激引线可以连接到神经刺激器以进行递送疗法以治疗神经障碍，例如尿控制障碍，粪便控制障碍，性功能障碍和骨盆疼痛等。

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