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1. 发明授权

US09168091B2 Ablation apparatus and system to limit nerve conduction 有权
标题翻译：消融装置和系统来限制神经传导
公开(公告)号：US09168091B2
公开(公告)日：2015-10-27
申请号：US13570138
申请日：2012-08-08
申请人： William Michael Janssen , James Paul Newman , Ammon Balaster , Jeffrey Michael Buske
发明人： William Michael Janssen , James Paul Newman , Ammon Balaster , Jeffrey Michael Buske
IPC分类号： A61B18/12 , A61B18/14 , A61B19/00 , A61B17/00 , A61B18/00
CPC分类号： A61B18/1477 , A61B18/1206 , A61B18/16 , A61B34/20 , A61B90/30 , A61B2017/00482 , A61B2018/00434 , A61B2018/00577 , A61B2018/00702 , A61B2018/0072 , A61B2018/00732 , A61B2018/00761 , A61B2018/00988 , A61B2018/1467 , A61B2018/162 , A61B2090/0803 , A61B2090/0814 , A61B2090/3937 , G06F19/00
摘要： A method of managing a system of minimally invasive surgery. The management method includes providing a practitioner with a minimally invasive surgery system including a controller. One or more use parameters is stored to memory associated with the controller. In addition, an electrosurgical probe having its own memory is provided to mate with the remaining elements of the system. Complementary use parameters are stored in the memory of the probe. The management method also includes communicating and comparing the use parameters of the controller with the complementary use parameters of the probe and managing the use of the electrosurgical probe according to the use parameters.
摘要翻译：一种管理微创手术系统的方法。管理方法包括向从业者提供包括控制器的微创手术系统。将一个或多个使用参数存储到与控制器相关联的存储器中。此外，提供具有其自身存储器的电外科探头以与系统的其余元件配合。互补使用参数存储在探头的存储器中。管理方法还包括将控制器的使用参数与探针的补充使用参数进行通信和比较，并根据使用参数管理电外科探头的使用。

2. 发明授权

US09119628B1 Systems and devices to identify and limit nerve conduction 有权
标题翻译：识别和限制神经传导的系统和设备
公开(公告)号：US09119628B1
公开(公告)日：2015-09-01
申请号：US14602196
申请日：2015-01-21
申请人： Serene Medical, Inc.
发明人： Bankim H. Mehta , Scott A. McGill
IPC分类号： A61B18/14 , A61B18/12 , A61B18/00
CPC分类号： A61B18/1233 , A61B18/1206 , A61B18/1477 , A61B2018/00434 , A61B2018/00577 , A61B2018/00714 , A61B2018/0072 , A61B2018/00839 , A61B2018/00958 , A61B2018/1425
摘要： Methods and devices for improved precision in finding one or more nerves and then interrupting the transmission of neural signals through the target nerve. The treated nerve can be rendered incapable of transmitting neural signals for a select duration of time, where such a duration can be on a temporary basis (e.g., hours, days or weeks) or a longer term/permanent basis (e.g., months or years). One embodiment of the apparatus includes a precise energy source system which features energy transfer elements that are capable of creating areas of nerve destruction, inhibition and ablation with precision.
摘要翻译：用于提高精确度的一种或多种神经的方法和装置，然后中断通过目标神经传递神经信号。经治疗的神经可以使其不能在选定的持续时间内传输神经信号，其中这样的持续时间可以是临时的（例如，几小时，几天或几周）或更长期/永久的基础（例如，几个月或几年））。该装置的一个实施例包括精确的能源系统，其特征在于能够产生神经破坏区域，抑制和精确消融的能量传递元件。

3. 发明申请

US20160206362A1 SYSTEMS AND DEVICES TO IDENTIFY AND LIMIT NERVE CONDUCTION 审中-公开
标题翻译：系统和设备识别和限制神经传导
公开(公告)号：US20160206362A1
公开(公告)日：2016-07-21
申请号：US14602180
申请日：2015-01-21
申请人： Serene Medical, Inc.
发明人： Bankim H. MEHTA , James P. NEWMAN , Scott A. McGILL
IPC分类号： A61B18/08 , A61N1/18
CPC分类号： A61N1/18 , A61B18/1402 , A61B18/1477 , A61B2018/00005 , A61B2018/00434 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61B2018/00875 , A61B2218/002 , A61N1/0551 , A61N1/36014
摘要： Methods and devices for improved precision in finding one or more nerves and then interrupting the transmission of neural signals through the target nerve. The treated nerve can be rendered incapable of transmitting neural signals for a select duration of time, where such a duration can be on a temporarily basis (e.g., hours, days or weeks) or a longer term/permanent basis (e.g., months or years). One embodiment of the apparatus includes a precise energy source system which features energy transfer elements that are capable of creating areas of nerve destruction, inhibition and ablation with precision.
摘要翻译：用于提高精确度的一种或多种神经的方法和装置，然后中断通过目标神经传递神经信号。经治疗的神经可以使其不能在选择的持续时间内传递神经信号，其中这种持续时间可以暂时地（例如，小时，数天或数周）或长期/永久基础（例如，几个月或几年））。该装置的一个实施例包括精确的能源系统，其特征在于能够产生神经破坏区域，抑制和精确消融的能量传递元件。

4. 发明授权

US08938302B2 Treatment of headache 有权
标题翻译：治疗头痛
公开(公告)号：US08938302B2
公开(公告)日：2015-01-20
申请号：US14156033
申请日：2014-01-15
申请人： Serene Medical, Inc.
发明人： James P. Newman
IPC分类号： A61N1/00 , A61N1/36 , A61N5/06
CPC分类号： A61B18/02 , A61B18/1477 , A61B18/1492 , A61B18/20 , A61B18/24 , A61B2018/00321 , A61B2018/00434 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00839 , A61F7/0085 , A61F2007/0002 , A61M5/00 , A61M19/00 , A61N1/36017 , A61N1/36021 , A61N1/36075 , A61N5/022 , A61N5/0622 , A61N5/10 , A61N7/00 , A61N2005/0659 , A61N2005/0661 , A61N2005/0663 , A61N2005/067 , A61N2007/0004
摘要： Headache treatment methods are described and include providing an energy delivery device; locating a secondary or higher-order branch of a postganglionic nerve that provides innervation for a patient's head, by identifying a target region of the patient's head that includes the nerve branch; positioning, within the target region, a portion of the energy delivery device; and applying, from the positioned portion of the energy delivery device to the target region, an amount of energy effective to result in a stimulation activity of the nerve branch; and, after observing the stimulated nerve branch activity, delivering, from the energy delivery device to the nerve branch, energy in an amount effective to reduce a headache severity in the patient.
摘要翻译：描述头痛治疗方法，包括提供能量输送装置; 通过识别包括神经分支的患者头部的目标区域来定位节后神经的次级或更高级分支，为患者的头部提供神经支配; 在目标区域内定位能量输送装置的一部分; 以及从所述能量输送装置的所述定位部分向所述目标区域施加有效地导致所述神经分支的刺激活动的能量的量; 并且在观察刺激的神经分支活动后，从能量输送装置向神经分支输送能量以有效减少患者头痛严重程度的量。

5. 发明申请

US20140180360A1 TREATMENT OF HEADACHE 有权
标题翻译： HEADACHE治疗
公开(公告)号：US20140180360A1
公开(公告)日：2014-06-26
申请号：US14156033
申请日：2014-01-15
申请人： Serene Medical, Inc.
发明人： James P. NEWMAN
IPC分类号： A61N1/36 , A61N5/06
CPC分类号： A61B18/02 , A61B18/1477 , A61B18/1492 , A61B18/20 , A61B18/24 , A61B2018/00321 , A61B2018/00434 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00839 , A61F7/0085 , A61F2007/0002 , A61M5/00 , A61M19/00 , A61N1/36017 , A61N1/36021 , A61N1/36075 , A61N5/022 , A61N5/0622 , A61N5/10 , A61N7/00 , A61N2005/0659 , A61N2005/0661 , A61N2005/0663 , A61N2005/067 , A61N2007/0004
摘要： Headache treatment methods are described and include providing an energy delivery device; locating a secondary or higher-order branch of a postganglionic nerve that provides innervation for a patient's head, by identifying a target region of the patient's head that includes the nerve branch; positioning, within the target region, a portion of the energy delivery device; and applying, from the positioned portion of the energy delivery device to the target region, an amount of energy effective to result in a stimulation activity of the nerve branch; and, after observing the stimulated nerve branch activity, delivering, from the energy delivery device to the nerve branch, energy in an amount effective to reduce a headache severity in the patient.
摘要翻译：描述头痛治疗方法，包括提供能量输送装置; 通过识别包括神经分支的患者头部的目标区域来定位节后神经的次级或更高级分支，为患者的头部提供神经支配; 在目标区域内定位能量输送装置的一部分; 以及从所述能量输送装置的所述定位部分向所述目标区域施加有效地导致所述神经分支的刺激活动的能量的量; 并且在观察刺激的神经分支活动后，从能量输送装置向神经分支输送能量以有效减少患者头痛严重程度的量。

6. 发明申请

US20080221518A1 SYSTEM AND METHOD USING THE RECTAL MUCOSAL MEMBRANE FOR INDUCING HYPOTHERMIA AND WARMING 失效
标题翻译：使用角膜膜诱导假性皮炎和变暖的系统和方法
公开(公告)号：US20080221518A1
公开(公告)日：2008-09-11
申请号：US12116257
申请日：2008-05-07
申请人： Gilbert R. Gonzales
发明人： Gilbert R. Gonzales
IPC分类号： A61F7/12
CPC分类号： A61F7/123 , A61F2007/0028 , A61F2007/0054
摘要： A system and method for cooling and warming the central nervous system of a patient comprises a delivery tube with one of the ends couplable to a supply of fluid. A head structure is coupled to the other end of the delivery tube and cooling or warming fluid is directed through the tube to the head structure. The head structure is configured to be placed within the rectal cavity of a patient such that either a contact surface on the head structure or the fluid itself directly contacts a portion of the rectal mucosal membrane. A means for reversing the vertebral venous flow of blood through Batson's plexus supplies cooled or warmed blood directly to the vertebral structures. Unique methods of utilizing the system to selectively cool and warm the central nervous system structures of a patient are set forth herein.
摘要翻译：用于冷却和加热患者的中枢神经系统的系统和方法包括一个输送管，其中一个端部可连接到流体供应。头部结构联接到输送管的另一端，并且冷却或加温流体通过管被引导到头部结构。头部结构被配置为放置在患者的直肠腔内，使得头部结构上的接触表面或流体本身直接接触直肠粘膜的一部分。通过Batson's丛将血液的脊椎静脉血流逆转，将冷却或加热的血液直接供给脊椎结构的手段。本文阐述了利用系统选择性地冷却和温暖患者的中枢神经系统结构的独特方法。

7. 发明授权

US07387638B2 System and method using the rectal mucosal membrane for inducing hypothermia and warming 失效
标题翻译：使用直肠粘膜诱导低温和升温的系统和方法
公开(公告)号：US07387638B2
公开(公告)日：2008-06-17
申请号：US11224363
申请日：2005-09-12
申请人： Gilbert R. Gonzales
发明人： Gilbert R. Gonzales
IPC分类号： A61F7/00
CPC分类号： A61F7/123 , A61F2007/0028 , A61F2007/0054
摘要： A system and method for cooling and warming the central nervous system of a patient comprises a delivery tube with one of the ends couplable to a supply of fluid. A head structure is coupled to the other end of the delivery tube and cooling or warming fluid is directed through the tube to the head structure. The head structure is configured to be placed within the rectal cavity of a patient such that either a contact surface on the head structure or the fluid itself directly contacts a portion of the rectal mucosal membrane. A means for reversing the vertebral venous flow of blood through Batson's plexus supplies cooled or warmed blood directly to the vertebral structures. Unique methods of utilizing the system to selectively cool and warm the central nervous system structures of a patient are set forth herein.
摘要翻译：用于冷却和加热患者的中枢神经系统的系统和方法包括一个输送管，其中一个端部可连接到流体供应。头部结构联接到输送管的另一端，并且冷却或加温流体通过管被引导到头部结构。头部结构构造成放置在患者的直肠腔内，使得头部结构上的接触表面或流体本身直接接触直肠粘膜的一部分。通过Batson's丛将血液的脊椎静脉血流逆转，将冷却或加热的血液直接供给脊椎结构的手段。本文阐述了利用系统选择性地冷却和温暖患者的中枢神经系统结构的独特方法。

8. 发明授权

US10548660B2 Ablation apparatus and system to limit nerve conduction 有权
公开(公告)号：US10548660B2
公开(公告)日：2020-02-04
申请号：US14852983
申请日：2015-09-14
申请人： Serene Medical, Inc.
发明人： William M. Janssen , James P. Newman , Ammon B. Balaster , Jeffrey M. Buske
IPC分类号： A61B18/12 , A61B18/14 , A61B90/30 , A61B18/16 , A61B90/00 , A61B18/00 , A61B17/00
摘要： A method of managing a system of minimally invasive surgery. The management method includes providing a practitioner with a minimally invasive surgery system including a controller. One or more use parameters is stored to memory associated with the controller. In addition, an electrosurgical probe having its own memory is provided to mate with the remaining elements of the system. Complementary use parameters are stored in the memory of the probe. The management method also includes communicating and comparing the use parameters of the controller with the complementary use parameters of the probe and managing the use of the electrosurgical probe according to the use parameters.

9. 发明申请

US20180161084A1 TREATMENT OF HEADACHE 审中-公开
公开(公告)号：US20180161084A1
公开(公告)日：2018-06-14
申请号：US15800996
申请日：2017-11-01
申请人： Serene Medical, Inc.
发明人： James P. NEWMAN
IPC分类号： A61B18/02 , A61M19/00 , A61B18/14 , A61B18/20 , A61B18/24 , A61F7/00 , A61M5/00 , A61N1/36 , A61N5/02 , A61N5/06 , A61N7/00 , A61N5/10 , A61B18/00 , A61N5/067
CPC分类号： A61B18/02 , A61B18/1477 , A61B18/1492 , A61B18/20 , A61B18/24 , A61B2018/00321 , A61B2018/00434 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00839 , A61F7/0085 , A61F2007/0002 , A61M5/00 , A61M19/00 , A61N1/36017 , A61N1/36021 , A61N1/36075 , A61N5/022 , A61N5/0622 , A61N5/10 , A61N7/00 , A61N2005/0659 , A61N2005/0661 , A61N2005/0663 , A61N2005/067 , A61N2007/0004
摘要： Headache treatment methods are described and include providing an energy delivery device; locating a secondary or higher-order branch of a postganglionic nerve that provides innervation for a patient's head, by identifying a target region of the patient's head that includes the nerve branch; positioning, within the target region, a portion of the energy delivery device; and applying, from the positioned portion of the energy delivery device to the target region, an amount of energy effective to result in a stimulation activity of the nerve branch; and, after observing the stimulated nerve branch activity, delivering, from the energy delivery device to the nerve branch, energy in an amount effective to reduce a headache severity in the patient.

10. 发明授权

US09833276B2 Treatment of headache 有权
公开(公告)号：US09833276B2
公开(公告)日：2017-12-05
申请号：US15201059
申请日：2016-07-01
申请人： Serene Medical, Inc.
发明人： James P. Newman
IPC分类号： A61N1/00 , A61B18/02 , A61N1/36 , A61N5/06 , A61B18/14 , A61B18/24 , A61M5/00 , A61B18/20 , A61F7/00 , A61M19/00 , A61N5/02 , A61N5/10 , A61N7/00 , A61B18/00 , A61N5/067
CPC分类号： A61B18/02 , A61B18/1477 , A61B18/1492 , A61B18/20 , A61B18/24 , A61B2018/00321 , A61B2018/00434 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00839 , A61F7/0085 , A61F2007/0002 , A61M5/00 , A61M19/00 , A61N1/36017 , A61N1/36021 , A61N1/36075 , A61N5/022 , A61N5/0622 , A61N5/10 , A61N7/00 , A61N2005/0659 , A61N2005/0661 , A61N2005/0663 , A61N2005/067 , A61N2007/0004
摘要： Headache treatment methods are described and include providing, an energy delivery device; locating a secondary or higher-order branch of a postganglionic nerve that provides innervation for a patient's head, by identifying a target region of the patient's head that includes the nerve branch; positioning, within the target region, a portion of the energy delivery device; and applying, from the positioned portion of the energy delivery device to the target region, an amount of energy effective to result in a stimulation activity of the nerve branch; and, after observing the stimulated nerve branch activity, delivering, from the energy delivery device to the nerve branch, energy in an amount effective to reduce a headache severity in the patient.

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