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1. 发明授权

US10777724B2 Hybrid solar system 有权
公开(公告)号：US10777724B2
公开(公告)日：2020-09-15
申请号：US16049205
申请日：2018-07-30
申请人： GAS TECHNOLOGY INSTITUTE , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ON BEHALF OF ITS MERCED CAMPUS , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ON BEHALF OF ITS BERKELEY CAMPUS
发明人： David Cygan , Hamid Abbasi , Aleksandr Kozlov , Roland Winston , Eli Yablonovitch
IPC分类号： H01L35/02 , H01L31/046 , H02S40/22 , H02S40/44 , F24S23/70
摘要： A hybrid solar system including a hybrid solar collector using non-imaging optics and photovoltaic components and a heat transfer and storage system in thermal communication with the hybrid solar collector, the heat transfer and storage system using particle laden gas as thermal media to simultaneously generate and store electricity and high temperature dispatchable heat.

2. 发明申请

US20190249172A1 METHODS AND COMPOSITIONS FOR GENE EDITING IN STEM CELLS 审中-公开
公开(公告)号：US20190249172A1
公开(公告)日：2019-08-15
申请号：US16077982
申请日：2017-02-16
申请人： The Regents of the University of California
发明人： Donald B. Kohn , Carmen Flores Bjurstroem
IPC分类号： C12N15/11 , C12N9/22 , C07K14/47
CPC分类号： C12N15/11 , C07K14/4747 , C12N9/22 , C12N15/10 , C12N15/102 , C12N2310/20 , C12N2800/80
摘要： The present disclosure provides methods for gene editing in stem cells. The methods generally involve modifying the stem cells by increasing the level of an apoptosis regulator in the stem cells; and introducing into the modified stem cells a genome editing composition.

3. 发明申请

US20190256824A1 MAMMALIAN CELLS DEVOID OF LACTATE DEHYDROGENASE ACTIVITY 审中-公开
公开(公告)号：US20190256824A1
公开(公告)日：2019-08-22
申请号：US16096784
申请日：2017-05-01
申请人： The Regents of the University of California
发明人： Hooman Hefzi , Nathan E. Lewis
IPC分类号： C12N9/04 , C12N9/12 , C12N15/90 , C12N5/071 , C12P21/00
摘要： Provided are mammalian cells devoid of lactate dehydrogenase activity.

4. 发明申请

US20200269323A1 SYNTHESIS OF ULTRA-THIN METAL NANOWIRES USING ORGANIC FREE RADICALS 审中-公开
公开(公告)号：US20200269323A1
公开(公告)日：2020-08-27
申请号：US16305387
申请日：2017-05-23
申请人： The Regents of the University of California
发明人： Peidong Yang , Fan Cui , Letian Dou , Zhiqiang Niu
IPC分类号： B22F9/24 , B22F1/00 , H01L31/0224 , H01L31/18
摘要： Provided are methods for synthesizing metal nanowires in solution using an organic reducing agent. A reaction mixture can be provided in solution with a metal salt, the organic reducing agent, and a solvent, where the solvent includes a surface ligand or consists of a surface ligand. The organic reducing agent, such as benzoin, can be decomposed in the reaction mixture to form organic free radicals that reduce metal ions of the metal salt into metal. The surface ligand of the solvent can coordinate with the metal in a manner so that metal nanowires are formed in solution. The diameter and morphology of the nanowires, reaction speed, reaction yield, and other features may be tunable by adjusting parameters such as reaction temperature and chemistry of the reducing agent.

5. 发明申请

US20230138861A1 RESUSCITATION AND VENTILATION ASYNCHRONY MONITOR 有权
公开(公告)号：US20230138861A1
公开(公告)日：2023-05-04
申请号：US17898182
申请日：2022-08-29
申请人： The Regents of the University of California
发明人： Michael Austin Johnson , Jason Adams , Jean-Pierre Delplanque , Justin Koos , Gregory Rehm
IPC分类号： A61H31/00 , A61B5/00
摘要： Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user. The device may suggest a corrective action based on the type of off-target ventilation detected. The device may also continuously analyze ventilation to determine changes in lung compliance over time and to identify pathological changes over time. The device may work within a network of devices and user interfaces via wired or wireless communication, and is not restricted to or dependent on the type of ventilatory device with which a patient is being supported.

6. 发明申请

US20230137168A1 Implantable Drug Delivery Devices For Localized Drug Delivery 有权
公开(公告)号：US20230137168A1
公开(公告)日：2023-05-04
申请号：US17911775
申请日：2020-12-18
申请人： The Regents of the University of California , Alessa Therapeutics, Inc.
发明人： Carlos Schuler , Maithill Rairkar , Pujan Desai , Maxime Daud , Maxime D. Rappaport , Pamela Munster , John Maroney , Margaret McLaughlin , Tobias H. Casab , Keith Hall , Scott Thomas
IPC分类号： A61K31/277 , A61K47/34 , A61K9/00 , A61P35/00 , A61P13/08
摘要： Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally, provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

7. 发明申请

US20230134238A1 WELL PLATE AND PETRI DISH FLUID EXCHANGE PLUG 有权
公开(公告)号：US20230134238A1
公开(公告)日：2023-05-04
申请号：US17906087
申请日：2021-03-12
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： Peyton J. Tebon , Darin Williams
IPC分类号： B01L3/00
摘要： The present invention provides fluidic (both air and liquid) exchange systems configured to retrofit standard cell/tissue culture well plates (6, 12, 24, 48, 96, 384, 1536 wells, and the like) and petri dishes by plugging into the openings of each well or dish.

8. 发明授权

US11640014B2 High frequency hybrid phononic metamaterials for optical and electrical devices 有权
公开(公告)号：US11640014B2
公开(公告)日：2023-05-02
申请号：US17034091
申请日：2020-09-28
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： Joshua Hihath , Omeed Momeni , Davide Donadio
IPC分类号： G02B1/00
摘要： Various metamaterials are disclosed. An example metamaterial comprises: a first portion with a plurality of nanoparticles; a second portion with a plurality of molecules configured to interlink with the plurality of nanoparticles; and a signal generator configured to provide a signal to the material. The first portion and the second portion of the material are configured to form a hybrid molecule-nanoparticle super-lattice. In some implementations, the first portion of the material is configured to have a mass configured to achieve, at least in part, a designated resonance frequency. The second portion of the material is, in some implementations, configured to have a molecular stiffness configured to achieve, at least in part, the designated resonance frequency. The signal generator is, in some implementations, configured to generate radio frequency (RF) signals.

9. 发明授权

US11639031B2 Photocurable resins for volumetric additive manufacturing 有权
公开(公告)号：US11639031B2
公开(公告)日：2023-05-02
申请号：US15930822
申请日：2020-05-13
申请人： Lawrence Livermore National Security, LLC , The Regents of the University of California
发明人： Maxim Shusteff , James Oakdale , Robert Matthew Panas , Christopher M. Spadaccini , Hayden K. Taylor , Brett Kelly , Indrasen Bhattacharya , Hossein Heidari
IPC分类号： B29C64/393 , C08F2/50 , B29C64/153 , B29C64/232 , B33Y50/02 , B33Y30/00 , C08F20/18 , B33Y10/00 , B29K33/00 , B33Y70/10 , B33Y40/20 , B29C64/268 , B29C64/282 , B29C64/264 , B29C64/124 , B29C64/277 , B29C64/241 , B29C64/386 , B29C64/106
摘要： Methods and materials for volumetric additive manufacturing, including computed axial lithography (“CAL”), using photosensitive resins comprising a photocurable resin prepolymer; a photoinitiator; and (optionally) a curing inhibitor. In various embodiments, such photosensitive polymers comprise (a) one or more monomer (or prepolymer) molecules, which form the backbone of the polymer network of the polymeric material and define its architecture; and (b) a photoinitiator that captures illumination energy and initiates polymerization.

10. 发明授权

US11639025B2 Methods for photo-induced metal printing 有权
公开(公告)号：US11639025B2
公开(公告)日：2023-05-02
申请号：US17045036
申请日：2019-04-03
申请人： The Regents of the University of California
发明人： Ximin He , Xingyun Yang , Dong Wu , Mutian Hua
IPC分类号： B29C64/124 , B29C64/314 , B29C64/245 , B29C64/255 , B29C64/286 , B29C64/268 , B33Y10/00 , B33Y30/00 , B33Y70/00 , B33Y80/00 , B33Y40/10 , B29K67/00 , B29L31/34
摘要： Methods and apparatus for fabricating high-resolution thin-layer metal patterns and 3D Metal structures are provided. The methods and apparatus operate via photo-(stereo)lithography at room temperature. The printed metal patterns, for example silver patterns, exhibit high electrical conductivity, comparable to or better than the conductivity of the silver printed by current laser sintering or thermal annealing at high temperature.

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