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1. 发明授权

US07885770B2 Methods for setting up, monitoring and performing analysis using capillary gel arrays 有权
标题翻译：使用毛细管凝胶阵列建立，监测和执行分析的方法
公开(公告)号：US07885770B2
公开(公告)日：2011-02-08
申请号：US10486870
申请日：2002-08-15
申请人： Peter Gill , Peter Koumi , Kam Tsang
发明人： Peter Gill , Peter Koumi , Kam Tsang
IPC分类号： G06F19/00
CPC分类号： G01N27/447 , C12Q1/6869 , Y10T436/144444 , C12Q2565/125
摘要： Set up methods, analysis methods and monitoring methods for capillary gel arrays are provided which rigorously determine the number of capillaries for which standards should be used and/or the capillaries in which standards should not be considered and/or for which performance is impaired. The invention includes methods for monitoring capillary gel array performance in which the capillary gel array performs, on a plurality of occasions, a size based separation on an unknown sample in one or more capillaries, a size based separation on a second standard in those one or more capillaries, and a size based separation on a standard in one or more other capillaries, comprising comparing the results of the sample to the results of the standards in which variation in a characteristic of the results from the capillaries provided with the standard are considered with time and variation of the characteristic outside a predetermined position to determine if one or more of the capillaries of the array are providing reduced performance. The invention provides rigour to the results obtained from capillary gel array analysis and prevents analysis being carried out on arrays which have developed problems or broken down.
摘要翻译：提供了设置毛细管凝胶阵列的方法，分析方法和监测方法，严格确定应使用标准品的毛细血管数量和/或不应考虑标准和/或损害性能的毛细血管。本发明包括用于监测毛细管凝胶阵列性能的方法，其中毛细管凝胶阵列在多个场合下在一个或多个毛细管中对未知样品进行基于尺寸的分离，在那些中的第二标准上执行基于尺寸的分离更多的毛细血管和基于一个或多个其他毛细血管标准的基于大小的分离，包括将样品的结果与标准结果进行比较，其中标准提供的毛细血管结果的特征变化被考虑与时间和特性在预定位置之外的变化，以确定阵列中的一个或多个毛细管是否提供降低的性能。本发明对从毛细管凝胶阵列分析获得的结果提供严格性，并且防止在已经出现问题或分解的阵列上进行分析。

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