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1. 发明申请

US20230137342A1 DRUG DETECTION USING COBALT THIOCYANATE AND EOSIN Y 有权
公开(公告)号：US20230137342A1
公开(公告)日：2023-05-04
申请号：US17910926
申请日：2021-03-11
申请人： Bowling Green State University , Vuronyx Technologies LLC
发明人： Jeremy Canfield , Jon Sprague , Sandip Agarwal , Kateland Herault , Mark Benjamin Volkin
IPC分类号： G01N21/29
摘要： Materials and methods for testing unknown substances for the presence of an opioid are described.

2. 发明申请

US20200216824A1 REGULATING PROTEIN SPONTANEOUS RUPTURES 审中-公开
公开(公告)号：US20200216824A1
公开(公告)日：2020-07-09
申请号：US16731648
申请日：2019-12-31
申请人： Bowling Green State University
发明人： H. Peter Lu
IPC分类号： C12N9/02 , C12N9/12 , C07K14/47
摘要： Protein rupture under compressive forces can be regulated by cations. More specifically, pico-Newton forces can cause rupture of protein molecules, as shown in examples with calmodulin (CaM) and tau proteins, among others. However, rupture does not occur in the presence of various concentrations of cation(s), thus elucidating new targets for disease therapy and providing therapies for neurodegenerative diseases or other conditions involving protein misfolding, dysfunction, or aggregation.

3. 发明授权

US10517997B1 Materials and methods using Fe3+ coordination to carboxylates 有权
公开(公告)号：US10517997B1
公开(公告)日：2019-12-31
申请号：US15212233
申请日：2016-07-16
申请人： Bowling Green State University
发明人： Alexis Ostrowski , Giuseppe Giammanco
IPC分类号： A61L27/52 , A61L27/04 , A61L27/26 , C12N5/00
摘要： Uronate-containing polysaccharide hydrogels that can be photo-patterned are described. The method involves forming a hydrogel and imetal-coordinating it with a reducible metallic cation and exposing the hydrogel to light in a desired pattern. The exposure to light reduces the metallic cation and results in an irreversible change in the elastic moduli and pore size of the irradiated portions of the patterned hydrogel. The method aha the benefit of allowing the user to produce such a hydrogel in any pattern desired. Patterned hydrogels and cell substrates formed by this method are also described.

4. 发明授权

US09453795B1 Method and related systems for mapping high ranges of total phosphate content in water using measurements of reflected light of off surface water 有权
标题翻译：使用测量离地表水反射光测量水中总磷酸盐含量的方法和相关系统
公开(公告)号：US09453795B1
公开(公告)日：2016-09-27
申请号：US13773574
申请日：2013-02-21
申请人： BOWLING GREEN STATE UNIVERSITY
发明人： Teagan Loew , Robert K. Vincent
IPC分类号： G01N21/55 , G01N21/27
CPC分类号： G01N21/55 , G01N21/31 , G01N33/182 , G01N2021/0118 , G01N2021/1793 , G01N2201/0616
摘要： The present invention relates to a method for determining the amount of total phosphate in a body of water from reflected light, and also includes systems for the measurement, calculation and transmission of data relating to or carrying out that method. In addition, the invention relates to methods and systems for determining other parameters of water quality from reflected light, for example, turbidity, dissolved oxygen and/or nitrogen.
摘要翻译：本发明涉及一种用于从反射光中测定水体中总磷酸盐的量的方法，还包括用于测量，计算和传输与该方法相关或执行的数据的系统。此外，本发明涉及用于从反射光（例如浊度，溶解氧和/或氮）确定水质的其它参数的方法和系统。

5. 发明授权

US09080154B1 Cancer stem cell survivor lines 有权
标题翻译：癌症干细胞幸存者系
公开(公告)号：US09080154B1
公开(公告)日：2015-07-14
申请号：US13855694
申请日：2013-04-02
申请人： BOWLING GREEN STATE UNIVERSITY
发明人： Roudabeh J. Jamasbi , Taghreed N. Almanaa , Michael E. Geusz
IPC分类号： C12N5/09
CPC分类号： C12N5/0693 , C12N5/0695
摘要： A method of determining the relative effectiveness of potential chemotherapeutic agents designed to inhibit neoplasm, growth or metastasis is described. The chemotherapeutic agent may be curcumin. The invention also relates to kits designed to aid in determining the relative effectiveness of potential chemotherapeutic agents. The invention also relates to cancer stem cell survivor lines that can be included in the kits and used in the method.
摘要翻译：描述了确定设计用于抑制肿瘤，生长或转移的潜在化学治疗剂的相对有效性的方法。化疗剂可以是姜黄素。本发明还涉及旨在帮助确定潜在化学治疗剂的相对有效性的试剂盒。本发明还涉及可以包含在试剂盒中并用于该方法的癌症干细胞幸存者系。

6. 发明授权

US08855940B2 Method of detecting coliform bacteria from reflected light 有权
标题翻译：从反射光中检测大肠菌群的方法
公开(公告)号：US08855940B2
公开(公告)日：2014-10-07
申请号：US13787785
申请日：2013-03-06
申请人： Bowling Green State University
发明人： Robert K. Vincent
IPC分类号： G01N33/48 , G01N31/00 , G06G7/48 , G06G7/58 , G01N21/31 , G01N33/18 , C12Q1/10 , G06F19/10
CPC分类号： C12Q1/10 , G01N21/31 , G01N33/18 , G01N2201/1293 , G06F19/10
摘要： The present invention relates to a method of detecting coliform bacteria in water from reflected light, and also includes devices for the measurement, calculation and transmission of data relating to that method.
摘要翻译：本发明涉及从反射光中检测水中大肠菌群的方法，还包括用于测量，计算和传输与该方法有关的数据的装置。

7. 发明授权

US08828279B1 Colloids of lead chalcogenide titanium dioxide and their synthesis 有权
标题翻译：铅硫族化物二氧化钛的胶体及其合成
公开(公告)号：US08828279B1
公开(公告)日：2014-09-09
申请号：US13082620
申请日：2011-04-08
申请人： Mikhail Zamkov , Krishna P. Acharya
发明人： Mikhail Zamkov , Krishna P. Acharya
IPC分类号： H01B1/06
CPC分类号： B01J13/0047 , B01J13/0026 , C01B3/02 , C01B19/007 , C01G21/21 , C01G23/07 , C01P2002/01 , C01P2002/72 , C01P2002/85 , C01P2004/04 , C01P2004/16 , C01P2004/32 , C01P2004/64 , C01P2004/90
摘要： The invention comprises the method of growing lead chalcogenide nanocrystals from the surface of titanium dioxide in organic solvents, lead chalcogenide/TiO2 nanocomposites colloids produced by the claimed method, and the application of lead chalcogenide/TiO2 nanostructures as an active absorbing element in nanocrystal-sensitized solar cells.
摘要翻译：本发明包括从有机溶剂中的二氧化钛表面生长铅硫族化物纳米晶体的方法，通过要求保护的方法制备的硫化氢/二氧化钛纳米复合物胶体，以及在硫化物/ TiO 2纳米结构中作为纳米晶体敏化的主要吸收元素的应用太阳能电池。

8. 发明授权

US08809512B2 RNA complexes, methods of their production and sensors and analytical methods involving same 有权
标题翻译： RNA复合物，其生产方法和传感器以及涉及其的分析方法
公开(公告)号：US08809512B2
公开(公告)日：2014-08-19
申请号：US13585225
申请日：2012-08-14
申请人： Neocles Leontis
发明人： Neocles Leontis
IPC分类号： C07H21/02
CPC分类号： C12Q1/6813 , Y10S977/728 , Y10S977/773 , C12Q2525/307 , C12Q2525/205
摘要： The invention includes RNA complexes comprising at least three monomeric units of an RNA molecule, each monomeric unit comprising an RNA polymer having first and second helical domains that have respective first and second binding sites, wherein the first binding sites are adapted to binding to one another and are not adapted to bind to the second binding sites, and the second binding sites are adapted to binding to one another and are not adapted to bind to the first binding sites; such that the at least three monomeric units are adapted to self-assemble by forming pairs of cognate interactions and so as to form the RNA complex in a circular closed complex. The invention also includes derivatives of these complexes including aptamers, and analytical methods and devices using same.
摘要翻译：本发明包括包含RNA分子的至少三个单体单元的RNA复合物，每个单体单元包含具有第一和第二螺旋结构域的RNA聚合物，其具有相应的第一和第二结合位点，其中第一结合位点适于彼此结合并且不适于结合第二结合位点，并且第二结合位点适于彼此结合并且不适于结合第一结合位点; 使得所述至少三个单体单元适于通过形成一对同源相互作用而自组装，从而在环状闭合复合物中形成RNA复合物。本发明还包括这些复合物的衍生物，包括适体，以及使用其的分析方法和装置。

9. 发明授权

US08785002B1 High-energy triplet host materials, luminescent layer comprising the same, and organic electroluminescent device comprising the luminescent layer 失效
标题翻译：高能三重态主体材料，包含该发光层的发光层和包含发光层的有机电致发光器件
公开(公告)号：US08785002B1
公开(公告)日：2014-07-22
申请号：US12381247
申请日：2009-03-10
申请人： Pavel Anzenbacher, Jr. , Shin-ya Takizawa
发明人： Pavel Anzenbacher, Jr. , Shin-ya Takizawa
IPC分类号： H01L51/00 , C07D235/18
CPC分类号： C07D235/18 , C07D401/14 , C07D403/10 , C07D403/14 , C07D409/14 , C07D413/14 , H01L51/0072 , H01L51/5016
摘要： The present invention includes high triplet energy compositions of matter, methods of their manufacture, devices incorporating the compositions of matter, and methods of using those compositions of matter and devices. The devices incorporating the high triplet energy compositions of matter include electroluminescence devices including organic light-emitting diodes (OLEDs). The present invention also includes methods of using the compositions of matter, such as by operating the devices of the present invention incorporating them, to provide light through electroluminescence, as well as obtaining and/or operating devices of the present invention through the application of electrical energy or potential, as well as methods of providing light through electroluminescence through their operation.
摘要翻译：本发明包括物质的高三重态能量组成，其制造方法，结合物质组成的装置，以及使用这些物质和装置组合物的方法。包含物质的高三重态能量组成的装置包括包括有机发光二极管（OLED）的电致发光器件。本发明还包括使用物质组合物的方法，例如通过操作包含本发明的装置的装置，通过电致发光提供光，以及通过应用电气获得和/或操作本发明的装置能量或电位，以及通过其操作通过电致发光提供光的方法。

10. 发明授权

US08367369B2 Method and apparatus for detecting phycocyanin-pigmented algae and bacteria from reflected light 有权
标题翻译：用于从反射光中检测藻蓝蛋白色素藻类和细菌的方法和装置
公开(公告)号：US08367369B2
公开(公告)日：2013-02-05
申请号：US11499288
申请日：2006-08-04
申请人： Robert Vincent
发明人： Robert Vincent
IPC分类号： C12Q1/02
CPC分类号： G01N21/31 , G01N33/18 , G01N2201/1293
摘要： The present invention relates to a method of detecting phycocyanin algae or bacteria in water from reflected light, and also includes devices for the measurement, calculation and transmission of data relating to that method.
摘要翻译：本发明涉及从反射光中检测水中的藻蓝蛋白藻类或细菌的方法，还包括用于测量，计算和传输与该方法有关的数据的装置。

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