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1. 发明授权

US12064225B2 Pressure sensor and guide wire with hydrophilic material 有权
公开(公告)号：US12064225B2
公开(公告)日：2024-08-20
申请号：US17124864
申请日：2020-12-17
申请人： ST. JUDE MEDICAL COORDINATION CENTER BVBA
发明人： Shawn Boye , Fredrik Mahlin , Stefan Tiensuu , Niklas Borg , Johan Mattsson , Johan Grundin , Mats Hilmersson , Sara Sundler , Dean Hacker , Ryan Cerepak
IPC分类号： A61M25/00 , A61B5/00 , A61B5/021 , A61B5/0215 , A61B5/03
CPC分类号： A61B5/036 , A61B5/021 , A61B5/0215 , A61B5/6851 , A61B2562/0247 , A61B2562/17 , A61M2025/0002 , A61M2025/0003
摘要： A pressure sensor configured for biological pressure measurement at a distal end portion of an elongated member comprises a dissolvable hydrophilic material coated on a surface of the pressure sensor. A guide wire for biological pressure measurement may include a tube extending along a longitudinal axis of the guide wire; and a pressure sensor for biological pressure measurement, at least a portion of the pressure sensor being mounted within the tube. The pressure sensor comprises a pressure sensor membrane facing a top side of the tube. A circumferential wall of the tube includes at least six openings: a first distal opening, a second distal opening located on a right side of the tube, a third distal opening located on a left side of the tube, a first proximal opening, a second proximal opening located on a right side of the tube, and a third proximal opening located on a left side of the tube. The first distal opening is larger than the second and third distal openings, and the first proximal opening is larger than the second and third proximal openings.

2. 发明授权

US11883138B2 Cardiac cycle-based diagnostic systems and methods 有权
公开(公告)号：US11883138B2
公开(公告)日：2024-01-30
申请号：US17733010
申请日：2022-04-29
申请人： ST. JUDE MEDICAL COORDINATION CENTER BVBA
发明人： Johan Svanerudh
IPC分类号： A61B5/0215 , A61B5/00 , A61B5/026 , A61B5/02 , A61B8/04 , A61B6/00 , A61B90/00
CPC分类号： A61B5/02154 , A61B5/0035 , A61B5/0066 , A61B5/0084 , A61B5/026 , A61B5/0215 , A61B5/7203 , A61B5/7278 , A61B5/742 , A61B5/02007 , A61B6/504 , A61B8/04 , A61B2090/3782 , A61B2576/00
摘要： A method of determining one or more diagnostic metrics to assess a blood vessel using intravascular data includes: sampling a sensor of an intravascular data collection probe disposed in the blood vessel during a pullback of the intravascular data collection probe through the blood vessel to obtain sampled distal pressure (Pd) values; receiving, at an intravascular data processing system, the sampled distal pressure (Pd) values and proximal pressure (Pa) values; determining sets of Pd/Pa ratios, each set including Pd/Pa ratios that are determined through an entirety of one heart cycle; determining minimum Pd/Pa ratios, each of which is a minimum within one of the sets of Pd/Pa ratios over the entirety of the corresponding heart cycle; and controlling a display system to generate a plot of a moving average of the minimum Pd/Pa ratios over time during the pullback.

3. 发明申请

US20220265144A1 DEVICE FOR ACQUIRING PHYSIOLOGICAL VARIABLES MEASURED IN A BODY 有权
公开(公告)号：US20220265144A1
公开(公告)日：2022-08-25
申请号：US17741969
申请日：2022-05-11
申请人： ST. JUDE MEDICAL COORDINATION CENTER BVBA
发明人： Ulrik HÜBINETTE , Magnus SAMUELSSON
IPC分类号： A61B5/00 , A61B5/02 , A61B5/0215 , A61B5/0205 , A61B5/021 , A61B5/026
摘要： A system includes: an aortic pressure sensor configured to measure aortic blood pressure of an individual; a distal sensor configured to measure a parameter in a blood vessel; a receiver configured to receive both (i) a signal representing the measured aortic blood pressure value, and (ii) a signal representing the parameter, the receiver comprising a display configured to display data that is based on at least the measured aortic blood pressure value and the measured parameter; and a communication interface configured to (i) receive a signal representing the measured aortic blood pressure value from the aortic pressure sensor via a wired connection, (ii) provide a signal representing the measured aortic blood pressure value to a monitoring device via a wired connection, and (iii) send a signal representing the measured aortic blood pressure value to the receiver via a wireless connection.

4. 发明申请

US20220257127A1 CARDIAC CYCLE-BASED DIAGNOSTIC SYSTEMS AND METHODS 有权
公开(公告)号：US20220257127A1
公开(公告)日：2022-08-18
申请号：US17733010
申请日：2022-04-29
申请人： ST. JUDE MEDICAL COORDINATION CENTER BVBA
发明人： Johan SVANERUDH
IPC分类号： A61B5/0215 , A61B5/00 , A61B5/026
摘要： A method of determining one or more diagnostic metrics to assess a blood vessel using intravascular data includes: sampling a sensor of an intravascular data collection probe disposed in the blood vessel during a pullback of the intravascular data collection probe through the blood vessel to obtain sampled distal pressure (Pd) values; receiving, at an intravascular data processing system, the sampled distal pressure (Pd) values and proximal pressure (Pa) values; determining sets of Pd/Pa ratios, each set including Pd/Pa ratios that are determined through an entirety of one heart cycle; determining minimum Pd/Pa ratios, each of which is a minimum within one of the sets of Pd/Pa ratios over the entirety of the corresponding heart cycle; and controlling a display system to generate a plot of a moving average of the minimum Pd/Pa ratios over time during the pullback.

5. 发明授权

US11350832B2 Cardiac cycle-based diagnostic systems and methods 有权
公开(公告)号：US11350832B2
公开(公告)日：2022-06-07
申请号：US14837291
申请日：2015-08-27
申请人： ST. JUDE MEDICAL COORDINATION CENTER BVBA
发明人： Johan Svanerudh
IPC分类号： A61B5/0215 , A61B5/00 , A61B5/026 , A61B5/02 , A61B8/04 , A61B6/00 , A61B90/00
摘要： In part, the disclosure relates to computer-based methods, and systems suitable for evaluating a cardiac system using a diagnostic metric such as a pressure value-based ratio. Selection of a subset or portion of a cardiac cycle is avoided in one embodiment to increase reliability and usability of a diagnostic ratio and parameters described herein. In one embodiment, a minimum or a relative extrema of a series of diagnostic metrics plotted on a per cycle basis are used to inform diagnosis of a stenosis or other intravascular event or phenomena.

6. 发明授权

US10792473B2 Core wire having a flattened portion to provide preferential bending 有权
公开(公告)号：US10792473B2
公开(公告)日：2020-10-06
申请号：US15072021
申请日：2016-03-16
申请人： ST. JUDE MEDICAL COORDINATION CENTER BVBA
发明人： Sara Sundler , Michael S. Morrissey
IPC分类号： A61M25/09 , A61B5/00 , A61B5/02 , A61B5/026
摘要： A guide wire configured for intravascular insertion includes a core wire having a flattened portion configured to allow the core wire to preferentially bend in at least one plane that passes through a longitudinal axis of the core wire. A distal most end of the flattened portion is spaced from a distal most end of the core wire. The guide wire may further include a sensor element configured to measure a physiological variable in a living body and a coil surrounding a portion of the core wire.

7. 发明授权

US09566418B2 Sensor guide wire with micro-cable winding 有权
标题翻译：传感器导丝带微电缆绕组
公开(公告)号：US09566418B2
公开(公告)日：2017-02-14
申请号：US12739290
申请日：2008-10-24
申请人： Pär Von Malmborg
发明人： Pär Von Malmborg
IPC分类号： A61B5/04 , A61M25/09 , A61B5/0215 , A61B5/00 , A61B17/22
CPC分类号： A61M25/09 , A61B5/0215 , A61B5/6851 , A61B2017/22038 , A61B2562/028 , A61M2025/09133 , A61M2025/09183
摘要： A sensor guide wire for an intravascular measurement of a physiological variable in a living body includes a sensor region in a distal part of the sensor guide wire, a sensor element arranged in the sensor region, a male connector at a proximal part of the sensor guide wire, a least one electrical micro-cable connecting the male connector to the sensor element, and an elongated guide wire body arranged between the sensor region and the male connector. The at least one electrical micro-cable extends essentially helically around the guide wire body along the length of at least a part of the guide wire.
摘要翻译：用于生物体内生理变量的血管内测量的传感器导丝包括传感器导丝的远端部分的传感器区域，布置在传感器区域中的传感器元件，在传感器引导件的近端部分处的阳连接器电线，将阳连接器连接到传感器元件的至少一个电微电缆，以及布置在传感器区域和阳连接器之间的细长导丝体。所述至少一个电微电缆沿导丝的至少一部分的长度基本上螺旋地围绕导丝体主体延伸。

8. 发明申请

US20160249821A1 PRESSURE SENSOR AND GUIDE WIRE WITH SELF WETTING TUBE 审中-公开
标题翻译：压力传感器和带自动润湿管的导线
公开(公告)号：US20160249821A1
公开(公告)日：2016-09-01
申请号：US15053308
申请日：2016-02-25
申请人： ST. JUDE MEDICAL COORDINATION CENTER BVBA
发明人： Shawn BOYE , Fredrik MAHLIN , Stefan TIENSUU , Niklas BORG , Johan MATTSSON , Johan GRUNDIN , Mats HILMERSSON , Christian SPRINGE , Sara SUNDLER , Dean HACKER , Ryan CEREPAK
IPC分类号： A61B5/03 , A61B5/00 , A61B5/0215
CPC分类号： A61B5/036 , A61B5/021 , A61B5/0215 , A61B5/6851 , A61B2562/0247 , A61B2562/17 , A61M2025/0002 , A61M2025/0003
摘要： A guide wire for biological pressure measurement includes a tube extending along a longitudinal axis of the guide wire; and a pressure sensor for biological pressure measurement, at least a portion of the pressure sensor being mounted within the tube. The pressure sensor comprises a pressure sensor membrane facing a top side of the tube. A circumferential wall of the tube includes at least six openings: a first distal opening, a second distal opening located on a right side of the tube, a third distal opening located on a left side of the tube, a first proximal opening, a second proximal opening located on a right side of the tube, and a third proximal opening located on a left side of the tube. The first distal opening is larger than the second and third distal openings, and the first proximal opening is larger than the second and third proximal openings.
摘要翻译：用于生物压力测量的引导线包括沿着导丝的纵向轴线延伸的管; 以及用于生物压力测量的压力传感器，所述压力传感器的至少一部分安装在所述管内。压力传感器包括面向管的顶侧的压力传感器膜。管的周壁包括至少六个开口：第一远端开口，位于管右侧的第二远端开口，位于管左侧的第三远端开口，第一近端开口，第二远端开口近端开口位于管的右侧，第三近端开口位于管的左侧。第一远端开口大于第二和第三远端开口，第一近端开口大于第二和第三近端开口。

9. 发明申请

US20160218720A1 INTERFACE AND RELATED METHOD FOR CONNECTING SENSOR EQUIPMENT AND A PHYSIOLOGICAL MONITOR 有权
标题翻译：用于连接传感器设备和生理监视器的界面和相关方法
公开(公告)号：US20160218720A1
公开(公告)日：2016-07-28
申请号：US15088631
申请日：2016-04-01
申请人： ST. JUDE MEDICAL COORDINATION CENTER BVBA
发明人： Mattias TULLBERG , Mattias DAHLBERG
IPC分类号： H03L5/00 , A61B5/00 , A61B5/021
CPC分类号： H03L5/00 , A61B5/021 , A61B5/7203 , A61B5/7225 , A61B2560/0204 , A61B2562/22 , A61B2562/222 , A61B2562/225
摘要： An interface to connect sensor equipment and a physiological monitor includes a first connector to receive power from a first channel of the monitor and a second connector to receive power from a second channel of the monitor. The power from each of the first and second channels of the monitor is combined within the interface. The interface further includes a third connector to provide the combined power to the sensor equipment; a voltage converter to rescale the voltage of the combined power that is provided to the sensor equipment; and a scaling circuit to reduce the voltage of a signal representing a measured physiological parameter. The signal representing the measured physiological parameter is sent from the sensor equipment to the monitor. The interface is advantageous to allow sensor equipment to be sufficiently powered by a monitor that would not typically provide enough power.
摘要翻译：连接传感器设备和生理监视器的接口包括从监视器的第一通道接收电力的第一连接器和用于从监视器的第二通道接收电力的第二连接器。来自监视器的第一和第二通道中的每一个的功率在接口内组合。该接口还包括第三连接器以向传感器设备提供组合的功率; 电压转换器，用于重新调整提供给传感器设备的组合功率的电压; 以及缩放电路，以减少表示测量的生理参数的信号的电压。表示测量的生理参数的信号从传感器设备发送到监视器。该接口有利于允许传感器设备由通常不提供足够功率的监视器充分供电。

10. 发明授权

US09325326B2 Interface and related method for connecting sensor equipment and a physiological monitor 有权
标题翻译：连接传感器设备和生理监护仪的接口及相关方法
公开(公告)号：US09325326B2
公开(公告)日：2016-04-26
申请号：US13801870
申请日：2013-03-13
申请人： ST. JUDE MEDICAL SYSTEMS AB
发明人： Mattias Tullberg , Mattias Dahlberg
IPC分类号： H03L5/00 , A61B5/00
CPC分类号： H03L5/00 , A61B5/021 , A61B5/7203 , A61B5/7225 , A61B2560/0204 , A61B2562/22 , A61B2562/222 , A61B2562/225
摘要： An interface to connect sensor equipment and a physiological monitor includes a first connector to receive power from a first channel of the monitor and a second connector to receive power from a second channel of the monitor. The power from each of the first and second channels of the monitor is combined within the interface. The interface further includes a third connector to provide the combined power to the sensor equipment; a voltage converter to rescale the voltage of the combined power that is provided to the sensor equipment; and a scaling circuit to reduce the voltage of a signal representing a measured physiological parameter. The signal representing the measured physiological parameter is sent from the sensor equipment to the monitor. The interface is advantageous to allow sensor equipment to be sufficiently powered by a monitor that would not typically provide enough power.
摘要翻译：连接传感器设备和生理监视器的接口包括从监视器的第一通道接收电力的第一连接器和用于从监视器的第二通道接收电力的第二连接器。来自监视器的第一和第二通道中的每一个的功率在接口内组合。该接口还包括第三连接器以向传感器设备提供组合的功率; 电压转换器，用于重新调整提供给传感器设备的组合功率的电压; 以及缩放电路，以减少表示测量的生理参数的信号的电压。表示测量的生理参数的信号从传感器设备发送到监视器。该接口有利于允许传感器设备由通常不提供足够功率的监视器充分供电。

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