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1. 发明授权

US07889912B2 Method for real-time tracking of cardiac structures in 3D echocardiography 有权
标题翻译： 3D超声心动图心脏结构实时跟踪方法
公开(公告)号：US07889912B2
公开(公告)日：2011-02-15
申请号：US11775903
申请日：2007-07-11
申请人： Fredrik Orderud
发明人： Fredrik Orderud
IPC分类号： G06K9/00
CPC分类号： G06T7/20 , G06T2207/10136 , G06T2207/20116 , G06T2207/30048
摘要： A method for tracking motion and shape changes of a deformable model in a volumetric image sequence. The method is operable to predict the surface of a space from a 3D image, such as cardiac structures from a 3D ultrasound. The shape and position of a deformable model is predicted for each frame of an ultrasound image. Edge detection is then performed for each predicted point on the deformable model perpendicular to the model surface. The distances between the predicted and measured edges for the deformable model are measurements for a Kalman filter. The measurements are coupled with noise values that specify the spatial uncertainty of the edge detection. The measurement data are subsequently summed together in information space and combined with the prediction in the Kalman filter to estimate the position and deformation for the deformable model. The deformable model is then updated to generate an updated surface model.
摘要翻译：用于跟踪体积图像序列中的可变形模型的运动和形状变化的方法。该方法可操作以从3D图像预测空间的表面，例如来自3D超声的心脏结构。针对超声图像的每个帧预测可变形模型的形状和位置。然后对垂直于模型表面的可变形模型上的每个预测点执行边缘检测。可变形模型的预测边和测量边之间的距离是卡尔曼滤波器的测量。测量值与指定边缘检测的空间不确定度的噪声值相结合。随后将测量数据相加在信息空间中并结合卡尔曼滤波器中的预测来估计可变形模型的位置和变形。然后更新可变形模型以生成更新的表面模型。

2. 发明申请

US20100317931A1 Method, Device and Computer Program Product for Monitoring a Subject 有权
标题翻译：方法，设备和计算机程序用于监控主题的产品
公开(公告)号：US20100317931A1
公开(公告)日：2010-12-16
申请号：US12483404
申请日：2009-06-12
申请人： Mika Sarkela
发明人： Mika Sarkela
IPC分类号： A61B5/00
CPC分类号： G06F19/30 , A61B5/0476 , A61B5/72 , A61B5/7221 , A61B5/7235 , A61B5/743 , A61B2505/01 , A61B2505/03 , A61B2505/05 , G06F19/00 , G06F19/34 , G16H15/00 , G16H40/63 , G16H50/20 , G16H50/30 , Y10S128/923 , Y10S128/925
摘要： A method, device, and computer program product for monitoring the physiological state of a subject is disclosed. A first plurality of physiological signals are acquired from the subject and a second plurality of signal parameters are determined based on the first plurality of physiological signals. Relevant signal information is selected from among the signal information produced and at least one screen page is displayed at a time, thereby to make at least part of the signal information visible to a user. The signal information visible to the user on the at least one screen page may then be revised based on the selection and without user interaction, thereby to accelerate clinical decision-making and to diminish the possibility of undetected changes in the state of the subject.
摘要翻译：公开了一种用于监测受试者的生理状态的方法，装置和计算机程序产品。从对象获取第一多个生理信号，并且基于第一多个生理信号来确定第二多个信号参数。从所生成的信号信息中选择相关的信号信息，并且一次显示至少一个屏幕页面，从而使信号信息的至少一部分对用户可见。然后可以基于选择和没有用户交互来修改用户在至少一个屏幕页面上可见的信号信息，从而加速临床决策并减少未检测到的对象状态变化的可能性。

3. 发明申请

US20100249539A1 METHOD AND APPARATUS FOR DETERMINING AN INDICATOR OF AUTONOMIC NERVOUS SYSTEM STATE 审中-公开
标题翻译：用于确定自主神经系统状态指示器的方法和装置
公开(公告)号：US20100249539A1
公开(公告)日：2010-09-30
申请号：US12411775
申请日：2009-03-26
申请人： Markku Paloheimo
发明人： Markku Paloheimo
IPC分类号： A61B5/02 , A61B5/0402
CPC分类号： A61B5/6826 , A61B5/14551 , A61B5/4035 , A61B5/4821 , A61B5/4824 , A61B5/6838
摘要： A method and apparatus for determining an indicator of the level of nociception of a subject are disclosed. A parameter indicative of sympathetical activation in a subject is generated. To tackle inter-subject variability and to maintain low measurement delay with the help of reduced computational effort, changes in the parameter are monitored to detect a stable state of the parameter. Upon detection the stable state, a subject-specific scaling transformation intended to transform the parameter to an index on a predetermined index scale is determined. The scaling transformation is made dependent on at least one value detected for the parameter in connection with detection of the stable state. The scaling transformation is then applied to subsequent values of the parameter, thereby to transform the subsequent values to index values indicative of the level of nociception.
摘要翻译：公开了一种用于确定受试者的伤害感水平的指标的方法和装置。产生指示受试者中的交感激活的参数。为了解决受试者间的差异性并通过减少计算量来维持低的测量延迟，监测参数的变化以检测参数的稳定状态。在检测到稳定状态时，确定旨在将参数变换到预定索引量表上的索引的对象专用缩放变换。缩放变换取决于与检测稳定状态相关的参数检测到的至少一个值。然后将缩放变换应用于参数的后续值，从而将后续值转换为指示伤害感受程度的索引值。

4. 发明申请

US20100191117A1 Method and Device for Controlling Transmission Power of an Active Transducer 有权
标题翻译：控制有源传感器传输功率的方法和装置
公开(公告)号：US20100191117A1
公开(公告)日：2010-07-29
申请号：US12361901
申请日：2009-01-29
申请人： Serguei Kabakov
发明人： Serguei Kabakov
IPC分类号： A61B8/02 , H04L27/00
CPC分类号： A61B8/0866 , A61B8/02 , A61B8/4427 , A61B8/488 , A61B8/5269 , A61B2560/0209
摘要： A method of operating an ultrasound signal generator includes generating a stimulus signal and receiving a returned signal. The Signal to Noise Ratio (SNR) of the returned signal is computed. The SNR is compared to an optimal SNR range. A control signal is generated to control the transmission power of the stimulus signal. A new stimulus signal is generated at the new transmission power. A device for collecting and analyzing a quasi-periodic signal includes a SNR calculator that computes the SNR of a returned signal. A signal analysis selector selects between a first and a second signal analysis technique. A transmission power controller compares the computed SNR with an optimal SNR range for the selected technique and modifies the transmission power as a result of this comparison.
摘要翻译：操作超声信号发生器的方法包括产生刺激信号并接收返回的信号。计算返回信号的信噪比（SNR）。将SNR与最佳SNR范围进行比较。生成控制信号以控制刺激信号的发送功率。在新的传输功率下产生新的激励信号。用于收集和分析准周期信号的装置包括计算返回信号的SNR的SNR计算器。信号分析选择器在第一和第二信号分析技术之间进行选择。传输功率控制器将所计算的SNR与所选择的技术的最佳SNR范围进行比较，并且作为该比较的结果来修改发射功率。

5. 发明申请

US20100174202A1 METHOD AND SYSTEM FOR COMBINING OSCILLOMETRIC BLOOD PRESSURE ENVELOPE DATA OBTAINED FROM DIFFERENT SIGNAL PROCESSING PATHS 审中-公开
标题翻译：用于组合来自不同信号处理程序的OSCILOMETRIC BLOOD压力包数据的方法和系统
公开(公告)号：US20100174202A1
公开(公告)日：2010-07-08
申请号：US12350412
申请日：2009-01-08
申请人： Lawrence T. Hersh , Sai Kolluri , Bruce A. Friedman , Richard Medero
发明人： Lawrence T. Hersh , Sai Kolluri , Bruce A. Friedman , Richard Medero
IPC分类号： A61B5/0225
CPC分类号： A61B5/0225 , A61B5/02225 , A61B5/0402 , A61B5/1455
摘要： A blood pressure measurement system that utilizes a non-invasive blood pressure (NIBP) monitor having a blood pressure cuff and pressure transducer. The measurement system provides a plurality of separate processing techniques that each receive a plurality of oscillometric waveform sample values generated using the pressure transducer. Each of the processing techniques separately generates a set of envelope points based upon the oscillometric data values. The sets of envelope points are appropriately scaled such that the sets of scaled envelope points are combined with each other to create a set of combined, scaled envelope points. Various different methods can be used to scale the sets of envelope points prior to the combination of the scaled envelope points. Based upon the combination of scaled envelope points, the blood pressure is calculated and displayed by the NIBP monitor.
摘要翻译：一种血压测量系统，其利用具有血压袖带和压力换能器的非侵入性血压（NIBP）监测器。测量系统提供多个单独的处理技术，每个处理技术接收使用压力传感器产生的多个示波波形采样值。每个处理技术基于示波器数据值分别产生一组包络点。适当地缩放包络点集合，使得缩放包络点的集合彼此组合以创建一组组合的，缩放的包络点。可以使用各种不同的方法在缩放的包络点的组合之前缩放包络点集合。根据缩放的包络点的组合，由NIBP监视器计算和显示血压。

6. 发明授权

US07749164B2 System and method for the processing of alarm and communication information in centralized patient monitoring 有权
标题翻译：在集中式病人监护中处理报警和通讯信息的系统和方法
公开(公告)号：US07749164B2
公开(公告)日：2010-07-06
申请号：US11426992
申请日：2006-06-28
申请人： Carl C. Davis
发明人： Carl C. Davis
IPC分类号： A61B5/00
CPC分类号： G06F19/3418 , G06F19/00 , G06Q50/22 , G16H40/20 , Y10S128/92
摘要： A system and a method allowing a technician to monitor the condition of a plurality of patients and communicate their condition to an attending clinician. A centralized receiving station receives signals from each of the patients being monitored. A graphical user interface simultaneously displays an indication of patient condition for each of a plurality of patients. A technician utilizes this information to efficiently communicate the conditions of the patients to an attending clinician.
摘要翻译：一种允许技术人员监测多个患者的状况并将其状况传达给主治临床医生的系统和方法。集中式接收站接收来自被监测患者的信号。图形用户界面同时显示多个患者中的每一个的患者状况的指示。技术人员利用该信息来有效地将患者的状况传达给主治临床医师。

7. 发明申请

US20100169063A1 System and Method of Modeling the Pharmacodynamic Effect to Drugs Delivered to a Patient 审中-公开
标题翻译：对药物药效学建模的系统和方法
公开(公告)号：US20100169063A1
公开(公告)日：2010-07-01
申请号：US12347139
申请日：2008-12-31
申请人： Laurence M. Yudkovitch , Ronald P. Makin , Rene Coffeng , Michael D. Krajnak
发明人： Laurence M. Yudkovitch , Ronald P. Makin , Rene Coffeng , Michael D. Krajnak
IPC分类号： G06G7/48
CPC分类号： G06F19/3468 , A61M16/01 , A61M16/021 , A61M16/0833 , A61M16/085 , A61M16/18 , A61M2202/0208 , A61M2202/0283 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/502 , A61M2230/43 , A61M2230/437 , G16C20/30 , G16C20/80 , G16H50/50
摘要： A system and method of modeling the pharmacodynamic effect of drugs delivered to a patient. The system includes a model database comprising a first drug interaction model and a second drug interaction model. A processing unit determines a first pharmacodynamic effect and a second pharmacodynamic effect and using a dominance rule to compare the first pharmacodynamic effect and a second pharmacodynamic effect to determine a dominant interaction model. A graphical display connected to the processing unit presents the determined dominant interaction model. The method includes the steps of obtaining first, second, and third drug concentrations, applying a first model that models a first pharmacodynamic effect, applying a second model that models a second pharmacodynamic effect and comparing the first pharmacodynamic effect to the second pharmacodynamic effect to determine which of the first model and the second model is the dominant pharmacodynamic model, and presenting the determined dominant pharmacodynamic model on a graphic display.
摘要翻译：对递送给患者的药物的药效学建模的系统和方法。该系统包括包含第一药物相互作用模型和第二药物相互作用模型的模型数据库。处理单元确定第一药效动力学效应和第二药效学效应，并使用优势规则来比较第一药效学效应和第二药效学效应以确定显性相互作用模型。连接到处理单元的图形显示呈现确定的主导交互模型。该方法包括以下步骤：获得第一，第二和第三药物浓度，应用建模第一药效动力学效应的第一模型，应用建模第二药效动力学效应的第二模型，并将第一药效动力学效应与第二药效学效应比较以确定第一模型和第二模型中的哪一种是显性药效学模型，并且在图形显示上呈现确定的显性药效学模型。

8. 发明申请

US20100042429A1 SYSTEM AND METHOD FOR PROVIDING LOCALLY ADAPTIVE DECISION SUPPORT 审中-公开
标题翻译：用于提供局部自适应决策支持的系统和方法
公开(公告)号：US20100042429A1
公开(公告)日：2010-02-18
申请号：US12190693
申请日：2008-08-13
申请人： Shailja Dixit
发明人： Shailja Dixit
IPC分类号： G06Q50/00
CPC分类号： G06Q50/22 , G16H10/60 , G16H50/20 , G16H50/70 , Y02A90/22 , Y02A90/26
摘要： A system and method for providing adaptive decision support is disclosed in further detail herein. An embodiment of this system includes a local outcome report that documents a medical outcome, a difference engine that compares the local outcome report to a national outcome report and generates a localized rule, and a rule engine that receives patient data and applies the localized rule from the difference engine to the patient data to produce a prescribed treatment. An embodiment of the method disclosed herein begins with receiving local patient data and outcome data. The outcome data is compared to national outcome data and a local rule is generated from the comparison. Next, the local patient and the outcome data is analyzed and a standard rule is generated based upon this analysis. The standard rule and the local rule are then applied to the local patient data to generate a prescribed treatment.
摘要翻译：本文进一步详细公开了一种用于提供自适应决策支持的系统和方法。该系统的实施例包括记录医疗结果的局部结果报告，将本地结果报告与国家结果报告进行比较并产生本地化规则的差异引擎，以及接收患者数据并将本地化规则从差异引擎与患者数据产生规定的治疗。本文公开的方法的实施例开始于接收本地患者数据和结果数据。将结果数据与国家成果数据进行比较，并从比较生成本地规则。接下来，分析本地患者和结果数据，并基于该分析生成标准规则。然后将标准规则和局部规则应用于本地患者数据以产生规定的治疗。

9. 发明申请

US20090326342A1 METHOD, ARRANGEMENT AND SENSOR FOR NON-INVASIVELY MONITORING BLOOD VOLUME OF A SUBJECT 审中-公开
标题翻译：方法，安排和传感器非主动监测血液体积
公开(公告)号：US20090326342A1
公开(公告)日：2009-12-31
申请号：US12163305
申请日：2008-06-27
申请人： Matti Huiku
发明人： Matti Huiku
IPC分类号： A61B5/1455
CPC分类号： A61B5/14551
摘要： A method, arrangement and sensor for monitoring blood status of a subject are disclosed. In-vivo measurement signals indicative of absorption caused by blood are acquired at a plurality of measurement wavelengths. Based on the in-vivo measurement signals, successive values are determined for a hemoglobin parameter indicative of the concentration of hemoglobin in the blood of the subject and the blood volume status of the subject is monitored based on the successive values. The monitoring may involve determining the absolute value of the blood volume or relative changes in the blood volume. In one embodiment, the absolute value of the blood volume is indicated continuously together with hemoglobin concentration and composition.
摘要翻译：公开了一种用于监测受试者的血液状态的方法，装置和传感器。在多个测量波长下获取指示由血液引起的吸收的体内测量信号。基于体内测量信号，确定指示受试者血液中血红蛋白浓度的血红蛋白参数的连续值，并且基于连续值监测受试者的血液体积状态。监测可以涉及确定血液体积的绝对值或血液体积的相对变化。在一个实施方案中，血容量的绝对值与血红蛋白浓度和组成一起连续表示。

10. 发明授权

US07638897B2 Method and system for powering a patient monitoring system 有权
标题翻译：为病人监护系统供电的方法和系统
公开(公告)号：US07638897B2
公开(公告)日：2009-12-29
申请号：US11232502
申请日：2005-09-22
申请人： Roy D. Koski, II , David L. Schieble , James M. Gray , Alan E. Clapp , Paul D. Lindquist
发明人： Roy D. Koski, II , David L. Schieble , James M. Gray , Alan E. Clapp , Paul D. Lindquist
IPC分类号： H02J1/06 , A61B5/00
CPC分类号： H02J1/10 , H02J7/0024 , H02J7/0026 , H02J13/0003 , Y10T307/25 , Y10T307/50 , Y10T307/505
摘要： The present invention is a method and system for powering a patient monitoring system. The present invention is a modular patient monitoring system utilizing a bi-directional power bus to efficiently couple a multi-parameter acquisition device, a display and any number of expansion modules. Each coupled device includes a battery, enabling each device to send or receive power through the bi-directional bus. The method and system of the present invention utilizes power from any single battery or from any number of the batteries in the system, as charge is not transferred from one battery to another. The present invention allows for the batteries to charge when it is operated from AC mains derived power.
摘要翻译：本发明是一种为病人监护系统供电的方法和系统。本发明是利用双向电力总线来有效耦合多参数采集装置，显示器和任意数量的扩展模块的模块化患者监视系统。每个耦合设备包括一个电池，使每个设备能够通过双向总线发送或接收电力。本发明的方法和系统利用来自任何单个电池或系统中任何数量的电池的电力，因为电荷不从一个电池转移到另一个电池。本发明允许电池在从AC电源获得的电力下操作时进行充电。

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