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1. 发明申请

US20230073386A1 APPARATUS AND METHOD 有权
公开(公告)号：US20230073386A1
公开(公告)日：2023-03-09
申请号：US17798960
申请日：2021-02-12
申请人： UNIVERSITY OF NEWCASTLE UPON TYNE
发明人： William Earl SCOTT, III , Stuart Brian William KAY
IPC分类号： A01N1/02 , A61B46/10
摘要： A container unit (6) is provided for storing an organ or body tissue, wherein the container unit is configured as an insert for a storage apparatus and wherein the container unit comprises: a container body (602) defining a storage region; an inlet port (632) for connection to a fluid supply system to receive persufflation fluid; an outlet port (634) for connection to a said organ or body tissue stored in the container body; and a fluid processing device (604) comprising an internal passageway (636) connecting the inlet port to the outlet port, wherein the fluid processing device is configured to process, e.g. cool and humidify, persufflation fluid flowing through the internal passageway from the inlet port to the outlet port. The present disclosure also relates to a storage apparatus, a kit of parts, and a method of preparing an apparatus to store and preserve an organ or body tissue.

2. 发明授权

US10598051B2 Energy storage system 有权
公开(公告)号：US10598051B2
公开(公告)日：2020-03-24
申请号：US16067163
申请日：2017-01-04
申请人： University of Newcastle Upon Tyne
发明人： Huashan Bao , Anthony Paul Roskilly
IPC分类号： F01K25/08 , F01K3/12 , F01K25/00 , F25B15/16 , F25B17/08 , F25B27/02
摘要： There is disclosed an energy storage system. In particular, there is disclosed a chemisorption based energy storage system, able to provide electricity, heating or cooling depending on the desired energy output. The energy storage system includes a first chemical reactor containing a first sorbent material and a second chemical reactor containing a second sorbent material. The first and second chemical reactors are in mutual fluid connection such that a refrigerant fluid can flow from the first chemical reactor to the second chemical reactor, and from the second chemical reactor to the first chemical reactor. The first and second chemical reactors are further provided with means for putting heat in to, or taking heat out of, the first and/or the second chemical reactors. A heat exchanger module is also provided. The heat exchanger module is configured to select from a plurality of available heat sources, a heat source having the highest temperature and an expander module selectively connected to the first chemical reactor and the second chemical reactor via the heat exchanger module. The heat source is arranged to heat the refrigerant fluid prior to the refrigerant fluid passing through the expander module, and the heat exchanger is configured to recover a surplus heat from the highest temperature heat source. The expander module is configured to expand the refrigerant fluid. The means for putting heat in to, or taking heat out of, the first and/or the second chemical reactors provides a flow of refrigerant fluid between the expander module and the first and second chemical reactors, and wherein the expander module is operable to expand the refrigerant fluid to provide a variable work output depending on energy storage requirements.

3. 发明申请

US20190342102A1 AUTHENITICATION OF PHYSICAL OBJECT USING INTERNAL STRUCTURE 审中-公开
公开(公告)号：US20190342102A1
公开(公告)日：2019-11-07
申请号：US15972922
申请日：2018-05-07
申请人： University of Newcastle Upon Tyne
发明人： Feng Hao , Ehsan Toreini , Siamak F. Shahandashti
IPC分类号： H04L9/32 , G06K9/00 , H04L9/08 , G09C5/00
摘要： A method for preventing counterfeiting of an object (e.g. paper) is described. The method comprises capturing an image of at least a portion of the object, wherein the portion of the object whose image is captured is at least partially transparent, and wherein the captured image includes features of the internal structure of the object (e.g. the texture of the paper resulting from the arrangement of fibres from which the paper is made). The method further comprises generating, based on the image, a code that encodes features of the internal structure of the object, and recording the code. Generating the code may comprise applying a filter to the image to obtain a filtered image, and processing the filtered image to obtain a binary code. The filter may be a Gabor filter, and processing the filtered image may comprise applying a Gray code to the filtered image. The method may further comprise encrypting the binary code, and recording the code may comprise recording the encrypted binary code. A method for authenticating an object is also described. The method comprises capturing an image of at least a portion of the object, wherein the portion of the object whose image is captured is at least partially transparent, and wherein the captured image includes features of the internal structure of the object. The method further comprises generating, based on the image, a code that encodes features of the internal structure of the object, reading one or more reference values comprising at least a reference code, and authenticating the object based on the code and the reference code.

4. 发明申请

US20190168021A1 Optogenetic System and Method 审中-公开
公开(公告)号：US20190168021A1
公开(公告)日：2019-06-06
申请号：US16321389
申请日：2017-07-28
申请人： University of Newcastle Upon Tyne
发明人： Andrew Jackson , Mark Cunningham , Stuart Baker , Patrick Degenaar
IPC分类号： A61N5/06 , A61B5/0478 , A61B5/00
摘要： An optogenetic system and method for preventing or halting seizures. The system and method use a sensor for monitoring the activity of a neural network containing a group of target neurons, and generating an input signal indicative of said activity, the target neurons being excitatory neurons. Excitatory stimulation is delivered in the form of an optical signal by an optical stimulator to the target neurons, the optical signal being determined based on the input signal, to reduce the overall activity of the target neurons.

5. 发明授权

US10191062B2 Model gut system 有权
公开(公告)号：US10191062B2
公开(公告)日：2019-01-29
申请号：US15039172
申请日：2014-11-21
申请人： University of Newcastle Upon Tyne
发明人： Jeff Pearson , Iain Brownlee , Matt Wilcox , Peter Chater , David Houghton
IPC分类号： G09B23/30 , G01N33/66 , C12N9/94 , C12Q1/37 , G01N33/68 , G01N33/92 , C12Q1/40 , C12Q1/44 , G09B9/00
摘要： The invention relates to a Model Gut System (MGS) comprising a pancreatic phase consisting essentially of synthetic pancreatic juice comprising pancreatin and one or more suitable pancreatic diluent(s) at a pH from about 7 to about 9, preferably about 7.9 to about 8.2, and porcine bile.

6. 发明申请

US20190002809A1 CELL CULTURE 审中-公开
公开(公告)号：US20190002809A1
公开(公告)日：2019-01-03
申请号：US15770106
申请日：2016-10-21
申请人： University of Newcastle Upon Tyne
发明人： Fiona OAKLEY , Lee BORTHWICK , Clive GRIFFITHS , Michael DRINNAN
IPC分类号： C12M1/32 , C12M3/06 , C12N5/071 , G01N33/50
摘要： Aspects of the present invention relate to apparatus for use in cell and tissue culture techniques. Particularly, although not exclusively, embodiments of the present invention relate to apparatus which contribute to providing a dynamic cell culture environment. Also disclosed herein are methods for culturing cells and/or tissues, together with in vitro methods of testing drug efficacy as well as other subject matter.

7. 发明授权

US09999632B2 Inhibition of pancreatic lipase 有权
公开(公告)号：US09999632B2
公开(公告)日：2018-06-19
申请号：US15221144
申请日：2016-07-27
申请人： RD Biomed Limited , University of Newcastle upon Tyne
发明人： Johnathan Craig Richardson , Peter William Dettmar , Matthew David Wilcox , Iain Andrew Brownlee , Jeffrey Peter Pearson
IPC分类号： A61K31/734
CPC分类号： A61K31/734
摘要： The present invention provides the use of an alginate Io inhibit pancreatic lipase. The use may be directed to the control of weight in animals including human beings. Preferably the fraction of guluronate dimers in the alginate is at least 0.5.

8. 发明申请

US20180029893A1 AEROGELS 审中-公开
公开(公告)号：US20180029893A1
公开(公告)日：2018-02-01
申请号：US15548189
申请日：2016-02-16
申请人： UNIVERSITY OF NEWCASTLE UPON TYNE
发明人： LIDIJA SILLER , XIAO HAN
IPC分类号： C01B33/158 , B01J20/10 , B01J20/08 , B01J20/30 , B01J37/00 , C09K3/32 , B01J21/08 , B01J21/04 , B01J35/00 , C01F7/02 , B01J20/28
CPC分类号： C01B33/1585 , B01J20/08 , B01J20/103 , B01J20/28047 , B01J20/3064 , B01J21/04 , B01J21/08 , B01J35/0013 , B01J37/0018 , C01F7/02 , C09K3/32
摘要： This invention relates to methods of producing aerogels and composites thereof. In particular, the invention relates to methods of producing silica aerogels and composites thereof. The invention also relates to doped aerogels and doped silica aerogels. The method involves the use of alkaline solutions, and particularly aqueous alkaline solutions, during the aerogel drying process. The method is more energy efficient and cheaper than prior art methods.

9. 发明授权

US09862750B2 Recombinant polypeptide 有权
公开(公告)号：US09862750B2
公开(公告)日：2018-01-09
申请号：US14407424
申请日：2013-06-11
申请人： University of Newcastle Upon Tyne
发明人： Jeremy Lakey
IPC分类号： C07K14/00 , C07K14/24 , A61L27/22 , A61L27/52 , A61L15/32 , A61L15/60 , C12N15/70
CPC分类号： C07K14/24 , A61L15/32 , A61L15/60 , A61L27/227 , A61L27/52 , A61L2300/424 , C07K2319/00 , C12N15/70
摘要： The invention provides a chaperone/usher family polymer comprising at least one chaperone/usher family polypeptide monomer, wherein said at least one chaperone/usher family polypeptide monomer comprises an exogenous bioactive sequence.

10. 发明授权

US09068107B2 Process for stimulating production of methane from petroleum in subterranean formations 有权
公开(公告)号：US09068107B2
公开(公告)日：2015-06-30
申请号：US11569706
申请日：2005-05-27
申请人： Stephen Richard Larter , Ian McCutcheon Head , David Martin Jones , Michael Erdmann , Arnd Wilhelms
发明人： Stephen Richard Larter , Ian McCutcheon Head , David Martin Jones , Michael Erdmann , Arnd Wilhelms
IPC分类号： C12P5/02 , C09K8/582
CPC分类号： C09K8/582 , C12P5/023 , Y02E50/343 , Y02E60/324
摘要： A process for stimulating microbial methane production in a petroleum-bearing subterranean formation, comprising: (a) analyzing one or more components of the formation to determine characteristics of the formation environment; (b) detecting the presence of a microbial consortium, comprising at least one methanogenic microorganism, within the formation; (c) assessing whether the formation microorganisms are currently active; (d) determining whether the microbial consortium comprises one or more methanotrophic microorganism; (e) characterization of one or more microorganisms of the consortium, at least one of the members of the consortium being a methanogenic microorganism, and comparing the members of the consortium with at least one known microorganism having one or more known physiological and ecological characteristics; (f) characterization of one or more methanotrophic microorganisms of the consortium (if present), and comparing the members of the consortium with at least one known microorganism having one or more known physiological and ecological characteristics; (g) using information obtained from steps (a) through (e) for determining an ecological environment that promotes in situ microbial degradation of petroleum and promotes microbial generation of methane by at least one methanogenic microorganism of the consortium; (h) using information obtained from steps (a) and (f), if methanotrophic microorganisms are present, for determining an ecological environment that demotes in situ microbial degradation of methane by at least one methanotrophic microorganism of the consortium; and (i) modifying the formation environment based on the determinations of steps (g) and (h), if methanotrophic microorganisms are present, to stimulate microbial conversion of petroleums to methane while minimising methane destruction by adverse processes.

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