基本信息:
- 专利标题： 美洲短吻鳄Cathelicidin-AM抗菌肽及其编码序列和用途
- 专利标题（英）：Alligator mississrppinsis Cathelicidin-AM antibacterial peptide as well as coded sequence and application thereof
- 申请号：CN201310553924.X 申请日：2013-11-08
- 公开(公告)号：CN103665137B 公开(公告)日：2015-07-01
- 发明人： 汪猜 , 皮灿辉 , 陈荣
- 申请人： 广州和仕康生物技术有限公司
- 申请人地址： 广东省广州市高新技术产业开发区科学城科学大道182号创新大厦C2区第三层304单元
- 专利权人： 广州和仕康生物技术有限公司
- 当前专利权人： 长沙巨龙生物科技有限公司
- 当前专利权人地址： 广东省广州市高新技术产业开发区科学城科学大道182号创新大厦C2区第三层304单元
- 代理机构： 广州三环专利代理有限公司
- 代理人： 郝传鑫
- 主分类号： C07K14/46
- IPC分类号： C07K14/46 ; C12N15/75 ; C12N1/21 ; A23K1/16 ; A01N47/44 ; A61K38/17 ; A61P31/00 ; A23L3/3526
The invention provides an alligator mississrppinsis Cathelicidin-AM antibacterial peptide, a polynucleotide for coding the antibacterial peptide and an application of the antibacterial peptide. The antibacterial peptide has an amino acid sequence as shown in SEQ ID NO: 2. The polynucleotide for coding the antibacterial peptide has a nucleotide sequence containing the coded amino acid sequence as shown in SEQ ID NO: 2 or a complementary sequence of the nucleotide sequence. The antibacterial peptide has a remarkable inhibiting effect on various bacteria and has the minimal inhibitory concentration (MIC) of 62.5mug/mL for Echerichia coli (CMCC44102), Escherichia coli (ATCC25922) and Salmonella typhi (CMCC50115). The antibacterial peptide can be used for preparing feed additives, preservatives, agricultural biocontrol agents, therapeutic drug compositions for controlling microorganism infection and the like.
公开/授权文献:
- CN103665137A 美洲短吻鳄Cathelicidin-AM抗菌肽及其编码序列和用途 公开/授权日：2014-03-26