The invention relates to medicinal liquor for treating rheumatism and arthritis. A preparation method for the medicinal liquor comprises the following steps: cleaning 50-70g of caulis spatholobi, 50-70g of red flowers, 50-70g of monkshood, 30-50g of cassia twigs, 60-80g of ephedra and 90-120g of radix angelicae by mineral water respectively; then, soaking the raw materials into 900-1100 ml of 35%-45% sorghum liquor for 25-35 days, filtering residues and getting the liquor, filling the liquor into a container, sterilizing the liquor, and then sealing and storing, thereby obtaining the medicinal liquor. According to the medicinal liquor, the raw materials are easy to collect, the price is low, the raw materials are all natural and free of toxic and side effect, and the preparation method is simple and easy to operate. The medicinal liquor is suitable for various rheumatic diseases, and further can be used for symptoms such as numbness of limbs, ischialgia, cervical spondylosis and hyperostosis.