The invention relates to a pharmaceutical composition used for moderating physique. The pharmaceutical composition takes mulberry capable of nourishing and strengthening body, benefiting brain and improving intelligence as a monarch drug, takes honeysuckle capable of clearing heat and detoxifying body as a ministerial drug, and takes licorice capable of strengthening spleen and benefiting vital qi, clearing heat and detoxifying, expelling phlegm to arrest coughing, relaxing spasm and relieving pain, and coordinating the drug actions of a prescription as an adjuvant drug which is a wonderful formula. The prescription has excellent compatibility, in clinical practice, the pharmaceutical composition has good effect on individual health preserving and health caring, the pharmaceutical composition can be directly decocted for drinking, administration method is simple and convenient, pharmacological function is fast, persistence is good, and the pharmaceutical composition is in favor of recovery and maintenance of physique.