The invention belongs to the technical field of traditional Chinese medicine, and relates to a pharmaceutical composition for treating hyperostosis. The pharmaceutical composition is mainly prepared from, by weight, 15-25 parts of radix ophiopogonis, 10-20 parts of notopterygium, 10-20 parts of sabia japonica, 10-20 parts of vervain, 5-10 parts of cyperus alternifolius, 10-20 parts of schisandra propinqua, 5-12 parts of chickpeas, 5-12 parts of roots of kudzu vine, 5-12 parts of Chinese yam, 8-12 parts of allium macrostemon and 5-12 parts of liquorice. The pharmaceutical composition can promote blood circulation to remove blood stasis, soothe the channels and vessels, dispel cold and damp, strengthen tendons and bones and the like and has the advantages of being high in permeability, capable of becoming effective quickly, high in targeting property, capable of avoiding reoccurrence, easy and convenient to use, mild in side effect and the like.