
基本信息:
- 专利标题: 瑞香狼毒有效成分的集成化提取分离方法
- 专利标题(英):Integrated extracting and separating method for active ingredients of Chinese stellera roots
- 申请号:CN201510414030.1 申请日:2015-07-10
- 公开(公告)号:CN105315118A 公开(公告)日:2016-02-10
- 发明人: 李玉山
- 申请人: 李玉山
- 申请人地址: 陕西省西安市高新路25号瑞欣大厦16D
- 专利权人: 李玉山
- 当前专利权人: 李玉山
- 当前专利权人地址: 陕西省西安市高新路25号瑞欣大厦16D
- 主分类号: C07B63/00
- IPC分类号: C07B63/00 ; C07D311/16 ; C07D311/32 ; C07D311/40 ; C07D405/14 ; C07D307/33 ; C07D493/04 ; C07J63/00 ; C07D311/22 ; C07H15/26 ; C07H1/08 ; C07D311/18 ; C07D493/22
The invention relates to an integrated extracting and separating method for active ingredients of Chinese stellera roots. The method comprises the following steps that firstly, Chinese stellera roots are extracted, concentrated and added with water for dispersion; secondly, a concentrated solution is subjected to petroleum ether extraction, and chromatographic separation is carried out; thirdly, residual liquid obtained after petroleum ether extraction is subjected to diethyl ether extraction, and chromatographic separation is carried out; fourthly, residual liquid obtained after diethyl ether extraction is subjected to chloroform extraction, and chromatographic separation is carried out; fifthly, residual liquid obtained after chloroform extraction is subjected to ethyl acetate extraction, and chromatographic separation is carried out; sixthly, residual liquid obtained after ethyl acetate extraction is subjected to acetone extraction, and chromatographic separation is carried out. According to the method, one or more kinds of high-polarity mixed solvents are adopted for extracting and concentrating the active ingredients of Chinese stellera roots synchronously, extract of a mixture of all the ingredients is obtained, then the corresponding ingredients are extracted through solvents of different polarities according to the similarity and intermiscibility principle, and all monomer ingredients are obtained with the combination of different chromatographic separation methods. The technology is novel, unique and suitable for industrial production.
IPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07B | 有机化学的一般方法;所用的装置 |
------C07B63/00 | 纯化;分离;稳定化;添加剂的使用 |