The invention relates to medicine used for treating primary osteoporosis. The medicine is prepared from the following raw herbal materials by weight: 12 parts of fructus psoraleae, 8 parts of eucommiaulmoides, 8 parts of achyranthesbidentata, 3 parts of lotus leaf, 6 parts of alpiniakatsumadai, 8 parts ofeupatorium fortunei, 9 parts of cattail pollen and 12 parts of honeycomb. As fructus psoraleae can be used for warming and nourishing spleen and kidney, eucommiaulmoides can be used for nourishing liver and kidney, and strengthening muscles and bones, achyranthesbidentata can be used for nourishing liver and kidney, strengthening muscles and bones, removing stasis and clearing channels, lotus leaf can be used for sending up the lucid yang, alpiniakatsumadai can be used for strengthening the spleen and promoting appetite, eupatorium fortuneican be used for enlivening the spleen and promoting appetite, cattail pollen can be used for hemostasis and dispersing blood stasis, and honeycomb can be used for dispelling wind-evil and relieving pain, the medicine integrating the raw herbal materials has the efficacies of warming and invigorating kidney yang, strengthening muscles and bones, replenishing qi to invigorate the spleen, activating blood circulation and dredging collaterals, so as to treat primary osteoporosis. Clinical trials show that primary osteoporosis can be treated safely and effectively.