The invention relates to a medicine for treating sciatica. The medicine is prepared from, by weight, 9 parts of fructus corni, 8 parts of semen cuscutae, 8 parts of fructus psoraleae, 8 parts of prepared rehmannia roots, 9 parts of radix angelica sinensis, 6 parts of rhizoma corydalis, 6 parts of pseudo-ginseng, 6 parts of herba taxilli and 4 parts of licorice roots. According to the medicine for treating sciatica, fructus corni is used for tonifying the liver and the kidneys, semen cuscutae is used for tonifying the kidneys and nourishing the liver, fructus psoraleae is used for warming the spleen and tonifying the kidneys, prepared rehmannia roots are used for enriching the blood, replenishing the essence and nourishing marrow, radix angelica sinensis is used for replenishing blood and promoting blood circulation to arrest pain, rhizoma corydalis is used for activating blood and promoting qi circulation to relieve pain, pseudo-ginseng is used for invigorating the circulation of blood to settle pain, herba taxilli is used for expelling wind-damp and strengthening the bones and muscles, and licorice roots are used for coordinating the medicine actions of all the medicine materials. All the medicine materials jointly perform the effects of nourishing the liver and the kidneys, expelling damp and dispelling cold, nourishing the blood and promoting blood circulation, and dispelling wind to relieve pain, and the purpose of treating sciatica is achieved.